Click here to switch to the map view.

The map label for this gene is gamP [H]

Identifier: 56963845

GI number: 56963845

Start: 2200905

End: 2202302

Strand: Direct

Name: gamP [H]

Synonym: ABC2080

Alternate gene names: 56963845

Gene position: 2200905-2202302 (Clockwise)

Preceding gene: 56963844

Following gene: 56963846

Centisome position: 51.14

GC content: 44.35

Gene sequence:

>1398_bases
ATGAAAAGCTTTTTGCAGAAGTTTGGAAAATCGCTGCTGATACCAATTGTTGCTTTGCCAATTGCCGGACTGCTCCTTCG
ATTAAGTGCCGAGGATTTGCTGGACATCCCTCTATTCCAAGCATCCGGTGTCATTTTGGCTCAGATGGATGCGCTGATTG
CGATCGGAATTGCGATGGGGCTTGCAAAAACAAAGGATAAAGGAATACCGGCACTCACAGGTTTTCTGGCCATTCTTGTC
TTAAAAGAAGGATTAACAATTATGGACCCAGAGCTCAATATGAGCGTATTCGGAGGCGTATTGGCTGGTTTAATCGCAGC
CTTCATCTATAATAAGTTTAAAGATACAAAGCTACCAAGTATGCTGGCCTTTTTCAGCGGAGAAAAATTCCCTATTACGG
TTATTATCTTTACGATGATTCCAGTAGCTGGACTGATGTCATTAATTTGGCCATACGCACAGTCCGGTATTGATACGTTC
AGTAAAACGTTGATGGGGCTTGGCGCGCTAGGCGTGTTCATATTTGGATTCTTAAACCGCTTCTTACTGCCATTTGGTTT
GCACCATGTTGTAAATACGTACGTCTATTTTGGCTTGGGGGAATATGAGACGCCTTCTGGAGAAATTGTGAATGGTGAAA
TCACCCGCTTTTTAAGCGGCGACCCTACAGCCGGATACTTTATCGGCGGATTTTTTATCACGATGATGTTCGGTGTACCG
GCCATCGCTCTCGCCATTACCCGGGCTGCGAAGAAAAAGAAAGAAGAAACGAAGTCTTTAATGGCTTCAGGTGCCGGAAC
CTCTTTTATTACAGGGATTACAGAACCAGTGGAATTTACATTCTTGTTTACATCTCCGCTGTTGTACTTTATGCATGCGG
TATACACTGGGCTGGCAGGAGCTGTGCTTTATCTGTTGCAAATCAGGCACGGATTTTCATGGGGAGCCGGTGTCATTGAC
TTCGTCTTAAACTTGAACCTCGCAGATCGAGGGTTGCTCATCATTCCAGTTGGCCTTGCCTTTTTTGCACTGTACTATTT
CACGTTTTATTTTATGATTGTTAAAAAGGACATCCCCCTTATTGGCCGAGAAAAAGAGCTGGACTTTGGCGAACAATCTT
CAGAGGACGAGAAAGAGTTGAAGTTGTCCCATTCCAATCACGAGTACATGGCCAAGAAAGTATTGCAATTTATCGGCGGA
AAAGAAAACGTTATCACGAATGATAACTGCATGACGCGCCTTCGTCTCGAACTCCATGATACAGAAGTCGTAGACGTCGA
TCGCATTAAGCAAACAGGTGCCCACGGCGTCATCAAAATCGACAAAAACAACGTACAAATCGTCCTAGGCTCCGAGGCCA
CCATCGTCAAAAAAGAACTAGACAAATTATTGGAGTAA

Upstream 100 bases:

>100_bases
CTGATGAGGAAATCGTTACACGTGTTCGGTCACGTAAAGATATTCAACTGGTCACGTATCAATCGATCTAAATACTATGG
ACGATAGGGAGGCTTCTATG

Downstream 100 bases:

>100_bases
TGTCTCCAGTTAAATAACTTTTCGTATAATAAAAAGCCCGCGCCTGTAAAAAAACAAGGGACGGGCTTTGCTTTTTCAAT
GTTTCGAACTCATATTTATT

Product: PTS system, N-acetylglucosamine-specific enzyme II, ABC component

Products: NA

Alternate protein names: Glucosamine permease IIC component; PTS system glucosamine-specific EIIC component; Glucosamine-specific phosphotransferase enzyme IIB component; PTS system glucosamine-specific EIIB component; Glucosamine-specific phosphotransferase enzyme IIA component; PTS system glucosamine-specific EIIA component [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MKSFLQKFGKSLLIPIVALPIAGLLLRLSAEDLLDIPLFQASGVILAQMDALIAIGIAMGLAKTKDKGIPALTGFLAILV
LKEGLTIMDPELNMSVFGGVLAGLIAAFIYNKFKDTKLPSMLAFFSGEKFPITVIIFTMIPVAGLMSLIWPYAQSGIDTF
SKTLMGLGALGVFIFGFLNRFLLPFGLHHVVNTYVYFGLGEYETPSGEIVNGEITRFLSGDPTAGYFIGGFFITMMFGVP
AIALAITRAAKKKKEETKSLMASGAGTSFITGITEPVEFTFLFTSPLLYFMHAVYTGLAGAVLYLLQIRHGFSWGAGVID
FVLNLNLADRGLLIIPVGLAFFALYYFTFYFMIVKKDIPLIGREKELDFGEQSSEDEKELKLSHSNHEYMAKKVLQFIGG
KENVITNDNCMTRLRLELHDTEVVDVDRIKQTGAHGVIKIDKNNVQIVLGSEATIVKKELDKLLE

Sequences:

>Translated_465_residues
MKSFLQKFGKSLLIPIVALPIAGLLLRLSAEDLLDIPLFQASGVILAQMDALIAIGIAMGLAKTKDKGIPALTGFLAILV
LKEGLTIMDPELNMSVFGGVLAGLIAAFIYNKFKDTKLPSMLAFFSGEKFPITVIIFTMIPVAGLMSLIWPYAQSGIDTF
SKTLMGLGALGVFIFGFLNRFLLPFGLHHVVNTYVYFGLGEYETPSGEIVNGEITRFLSGDPTAGYFIGGFFITMMFGVP
AIALAITRAAKKKKEETKSLMASGAGTSFITGITEPVEFTFLFTSPLLYFMHAVYTGLAGAVLYLLQIRHGFSWGAGVID
FVLNLNLADRGLLIIPVGLAFFALYYFTFYFMIVKKDIPLIGREKELDFGEQSSEDEKELKLSHSNHEYMAKKVLQFIGG
KENVITNDNCMTRLRLELHDTEVVDVDRIKQTGAHGVIKIDKNNVQIVLGSEATIVKKELDKLLE
>Mature_465_residues
MKSFLQKFGKSLLIPIVALPIAGLLLRLSAEDLLDIPLFQASGVILAQMDALIAIGIAMGLAKTKDKGIPALTGFLAILV
LKEGLTIMDPELNMSVFGGVLAGLIAAFIYNKFKDTKLPSMLAFFSGEKFPITVIIFTMIPVAGLMSLIWPYAQSGIDTF
SKTLMGLGALGVFIFGFLNRFLLPFGLHHVVNTYVYFGLGEYETPSGEIVNGEITRFLSGDPTAGYFIGGFFITMMFGVP
AIALAITRAAKKKKEETKSLMASGAGTSFITGITEPVEFTFLFTSPLLYFMHAVYTGLAGAVLYLLQIRHGFSWGAGVID
FVLNLNLADRGLLIIPVGLAFFALYYFTFYFMIVKKDIPLIGREKELDFGEQSSEDEKELKLSHSNHEYMAKKVLQFIGG
KENVITNDNCMTRLRLELHDTEVVDVDRIKQTGAHGVIKIDKNNVQIVLGSEATIVKKELDKLLE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786894, Length=471, Percent_Identity=38.0042462845011, Blast_Score=296, Evalue=3e-81,
Organism=Escherichia coli, GI1787343, Length=487, Percent_Identity=35.9342915811088, Blast_Score=288, Evalue=4e-79,
Organism=Escherichia coli, GI1787908, Length=520, Percent_Identity=29.2307692307692, Blast_Score=213, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 51023; Mature: 51023

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFLQKFGKSLLIPIVALPIAGLLLRLSAEDLLDIPLFQASGVILAQMDALIAIGIAMG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHH
LAKTKDKGIPALTGFLAILVLKEGLTIMDPELNMSVFGGVLAGLIAAFIYNKFKDTKLPS
HHHCCCCCCHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHH
MLAFFSGEKFPITVIIFTMIPVAGLMSLIWPYAQSGIDTFSKTLMGLGALGVFIFGFLNR
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLPFGLHHVVNTYVYFGLGEYETPSGEIVNGEITRFLSGDPTAGYFIGGFFITMMFGVP
HHHHHHHHHHHHHHHEECCCCCCCCCCCEECCHHHHEECCCCCCHHHHHHHHHHHHHHHH
AIALAITRAAKKKKEETKSLMASGAGTSFITGITEPVEFTFLFTSPLLYFMHAVYTGLAG
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
AVLYLLQIRHGFSWGAGVIDFVLNLNLADRGLLIIPVGLAFFALYYFTFYFMIVKKDIPL
HHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCC
IGREKELDFGEQSSEDEKELKLSHSNHEYMAKKVLQFIGGKENVITNDNCMTRLRLELHD
CCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCCEEEEEEEECC
TEVVDVDRIKQTGAHGVIKIDKNNVQIVLGSEATIVKKELDKLLE
CCEEEHHHHHHCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKSFLQKFGKSLLIPIVALPIAGLLLRLSAEDLLDIPLFQASGVILAQMDALIAIGIAMG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHH
LAKTKDKGIPALTGFLAILVLKEGLTIMDPELNMSVFGGVLAGLIAAFIYNKFKDTKLPS
HHHCCCCCCHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHH
MLAFFSGEKFPITVIIFTMIPVAGLMSLIWPYAQSGIDTFSKTLMGLGALGVFIFGFLNR
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLPFGLHHVVNTYVYFGLGEYETPSGEIVNGEITRFLSGDPTAGYFIGGFFITMMFGVP
HHHHHHHHHHHHHHHEECCCCCCCCCCCEECCHHHHEECCCCCCHHHHHHHHHHHHHHHH
AIALAITRAAKKKKEETKSLMASGAGTSFITGITEPVEFTFLFTSPLLYFMHAVYTGLAG
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
AVLYLLQIRHGFSWGAGVIDFVLNLNLADRGLLIIPVGLAFFALYYFTFYFMIVKKDIPL
HHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCC
IGREKELDFGEQSSEDEKELKLSHSNHEYMAKKVLQFIGGKENVITNDNCMTRLRLELHD
CCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCCEEEEEEEECC
TEVVDVDRIKQTGAHGVIKIDKNNVQIVLGSEATIVKKELDKLLE
CCEEEHHHHHHCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 7751298 [H]