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The map label for this gene is recU

Identifier: 56963819

GI number: 56963819

Start: 2169768

End: 2170391

Strand: Direct

Name: recU

Synonym: ABC2054

Alternate gene names: 56963819

Gene position: 2169768-2170391 (Clockwise)

Preceding gene: 56963815

Following gene: 56963820

Centisome position: 50.41

GC content: 44.23

Gene sequence:

>624_bases
ATGCCAATTCGTTACCCGAATGGACAGCCCTACTCACGCAGCCCTAAACAAGGGCAAGCAAAAAAGCCACTACCAGCCGA
TACATATAGCGGTCGCGGCATGACACTCGAGCAGGACATTGACGAGGCAAATTTATATTATTTGAGCCAACAACGGGCAG
TCGTCCATAAAAAACCGACACCGGTACAAATTGTCAAAGTTGATTACCCAAAACGAAGTGCAGCTGTCATCCGTGAGGCT
TATTTTAAGCAAGCTTCAACGACAGATTATAATGGCGTTTACCGAGGCGCCTATATCGATTTCGAAGCAAAAGAAACAAA
AAACAAAACGTCGTTCCCGCTGAAAAACATTCATCCCCACCAAGTTGATCACATGCGGGAAGTCAGCAAACACGGCGGCA
TTTGTTTTGTGCTCATTCGCTTTTTTCAATCGGCAGAAGTTTTTTTACTTGATGCCAAACATTTAATTGATTATTATGAC
AATCAGGACGTACGGAAGTCGATTAAAAAAACAGAGATTGAACGACTTGGACACCAAGTAAAAACGGGCCTGCATCCGCC
CATTGATTATTTGCGGACGCTTGACGCCGTTTACTTTAATGGGGATGCAAAGGAGAGGACGTAA

Upstream 100 bases:

>100_bases
GGACGACAAATATGCTAAAATGAAAGAATGACTATGCTTTGTTACCTTTCCGCATATAGACAAAAAACATACAAAAGCCA
TTTGGAAAGGATGTGGGCAA

Downstream 100 bases:

>100_bases
GACATGTCAGATGAGTATAAATCAAGGCAGGAGCGCAAAAAAGCCCAAAATCGCAGCAAAAATGGCACAACGCCAAAAAA
TGGTGGGAAGAAACGAAGCG

Product: Holliday junction-specific endonuclease

Products: NA

Alternate protein names: Recombination protein U homolog

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MPIRYPNGQPYSRSPKQGQAKKPLPADTYSGRGMTLEQDIDEANLYYLSQQRAVVHKKPTPVQIVKVDYPKRSAAVIREA
YFKQASTTDYNGVYRGAYIDFEAKETKNKTSFPLKNIHPHQVDHMREVSKHGGICFVLIRFFQSAEVFLLDAKHLIDYYD
NQDVRKSIKKTEIERLGHQVKTGLHPPIDYLRTLDAVYFNGDAKERT

Sequences:

>Translated_207_residues
MPIRYPNGQPYSRSPKQGQAKKPLPADTYSGRGMTLEQDIDEANLYYLSQQRAVVHKKPTPVQIVKVDYPKRSAAVIREA
YFKQASTTDYNGVYRGAYIDFEAKETKNKTSFPLKNIHPHQVDHMREVSKHGGICFVLIRFFQSAEVFLLDAKHLIDYYD
NQDVRKSIKKTEIERLGHQVKTGLHPPIDYLRTLDAVYFNGDAKERT
>Mature_206_residues
PIRYPNGQPYSRSPKQGQAKKPLPADTYSGRGMTLEQDIDEANLYYLSQQRAVVHKKPTPVQIVKVDYPKRSAAVIREAY
FKQASTTDYNGVYRGAYIDFEAKETKNKTSFPLKNIHPHQVDHMREVSKHGGICFVLIRFFQSAEVFLLDAKHLIDYYDN
QDVRKSIKKTEIERLGHQVKTGLHPPIDYLRTLDAVYFNGDAKERT

Specific function: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair

COG id: COG3331

COG function: function code R; Penicillin-binding protein-related factor A, putative recombinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recU family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RECU_BACSK (Q5WGB6)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_175550.1
- HSSP:   P39792
- ProteinModelPortal:   Q5WGB6
- SMR:   Q5WGB6
- STRING:   Q5WGB6
- EnsemblBacteria:   EBBACT00000049700
- GeneID:   3202860
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC2054
- NMPDR:   fig|66692.3.peg.2358
- eggNOG:   COG3331
- GeneTree:   EBGT00050000001230
- HOGENOM:   HBG571967
- OMA:   HYPKRSA
- ProtClustDB:   PRK02234
- BioCyc:   BCLA66692:ABC2054-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00130
- InterPro:   IPR004612
- InterPro:   IPR011335
- PIRSF:   PIRSF037785
- TIGRFAMs:   TIGR00648

Pfam domain/function: PF03838 RecU; SSF52980 Restrict_endonuc_II-like_core

EC number: NA

Molecular weight: Translated: 23863; Mature: 23732

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRYPNGQPYSRSPKQGQAKKPLPADTYSGRGMTLEQDIDEANLYYLSQQRAVVHKKPT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCEEEEECCCHHCCCCCC
PVQIVKVDYPKRSAAVIREAYFKQASTTDYNGVYRGAYIDFEAKETKNKTSFPLKNIHPH
CEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEECEEEEEECHHCCCCCCCCCCCCCCH
QVDHMREVSKHGGICFVLIRFFQSAEVFLLDAKHLIDYYDNQDVRKSIKKTEIERLGHQV
HHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
KTGLHPPIDYLRTLDAVYFNGDAKERT
HCCCCCCHHHHHHHHHHEECCCCCCCC
>Mature Secondary Structure 
PIRYPNGQPYSRSPKQGQAKKPLPADTYSGRGMTLEQDIDEANLYYLSQQRAVVHKKPT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCEEEEECCCHHCCCCCC
PVQIVKVDYPKRSAAVIREAYFKQASTTDYNGVYRGAYIDFEAKETKNKTSFPLKNIHPH
CEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEECEEEEEECHHCCCCCCCCCCCCCCH
QVDHMREVSKHGGICFVLIRFFQSAEVFLLDAKHLIDYYDNQDVRKSIKKTEIERLGHQV
HHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
KTGLHPPIDYLRTLDAVYFNGDAKERT
HCCCCCCHHHHHHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA