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The map label for this gene is sodF [H]

Identifier: 56963584

GI number: 56963584

Start: 1937418

End: 1938284

Strand: Direct

Name: sodF [H]

Synonym: ABC1819

Alternate gene names: 56963584

Gene position: 1937418-1938284 (Clockwise)

Preceding gene: 56963582

Following gene: 56963589

Centisome position: 45.02

GC content: 45.67

Gene sequence:

>867_bases
GTGGATTCGCATGAGCAAGCATTAAGAAAATGGAAAGATGAGCTTGCCAGGCTTTGGAAAGAGCAGGAAAGCGAGTTTGT
CAGGTCCATAGGAGAAGAGCAAACACAGCCTTTTACAAAGTCGTTAAGCCAATTGGAATATGCGCTTGAACACGATCCTA
CACAAGCAAACGAACATGCTCAACACGCCTATGACTCATGGGTAGTAATGGCCGATTTAAGAGGAAAAGGGAAAAATAAC
AGCGTCCCCATCGGCGGTCATAGGCTACCACCAATGCCTTATTCATATAATGCGTTGGAACCGTACATTGATGCAAAGAC
CATGCGCCTTCATCATTTAAAGCATCATCAGACGTATGTCAATGATTTAAATAAAGCAGAGAAAGAAATGGAAAAGGCGA
GACGTACTGGAAATTATGATTTGATTAAGCATTGGGAGAGGGAAGCGGCGTTCAATGGGGCGGGTCATTATTTGCACACG
CTTTTTTGGCATGTCATGTCACCAAATGGGGGCGGAGAGCCGCAAGGGCTGCTAAAAGCAAGAATAACAGAAGACTTTGG
CTCCTTTCAAAAAATGAAAGCCCATTTTTCCAATGCTGCTGAAAAAGTCGAAGGCGGCGGCTGGGCGATGCTCATTTACG
CGCCGAGGTCCCACCGGTTAGAAATTCTTCAGGCGGAAAAGCACCAAAACCTTTCCCAACAAGACCAAGTGCCGCTGTTG
GTGTTGGATGTATGGGAGCACGCCTACTATTTAAAGTATCAAAATGAGCGTAAAGCGTATATTGAGGCATGGTGGAATGT
TGTGAACTGGAAGGAAGCTGAAAATCGTTACCGCCAGGCCTCGCAGTTAAAATGGGTGCCCTATTAA

Upstream 100 bases:

>100_bases
GAGATAAAGAAAGCGTTTCCCTTCAAATTTATACTTTTTTCGCAATTGGCCAAGAACAGTTGCATATACGTAGGGAGAAA
AGGAAAAAGGAGGGAATAAT

Downstream 100 bases:

>100_bases
AAAAACAAACCTAGGAGGGACCTAGATTTGTTTTTGTTTATAAAATCGGCGACAACAGCCGTGAAATTGACTCTTTAAAG
CGGACGCTTATTGGCCTGTT

Product: superoxide dismutase [Cu-Zn]

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MDSHEQALRKWKDELARLWKEQESEFVRSIGEEQTQPFTKSLSQLEYALEHDPTQANEHAQHAYDSWVVMADLRGKGKNN
SVPIGGHRLPPMPYSYNALEPYIDAKTMRLHHLKHHQTYVNDLNKAEKEMEKARRTGNYDLIKHWEREAAFNGAGHYLHT
LFWHVMSPNGGGEPQGLLKARITEDFGSFQKMKAHFSNAAEKVEGGGWAMLIYAPRSHRLEILQAEKHQNLSQQDQVPLL
VLDVWEHAYYLKYQNERKAYIEAWWNVVNWKEAENRYRQASQLKWVPY

Sequences:

>Translated_288_residues
MDSHEQALRKWKDELARLWKEQESEFVRSIGEEQTQPFTKSLSQLEYALEHDPTQANEHAQHAYDSWVVMADLRGKGKNN
SVPIGGHRLPPMPYSYNALEPYIDAKTMRLHHLKHHQTYVNDLNKAEKEMEKARRTGNYDLIKHWEREAAFNGAGHYLHT
LFWHVMSPNGGGEPQGLLKARITEDFGSFQKMKAHFSNAAEKVEGGGWAMLIYAPRSHRLEILQAEKHQNLSQQDQVPLL
VLDVWEHAYYLKYQNERKAYIEAWWNVVNWKEAENRYRQASQLKWVPY
>Mature_288_residues
MDSHEQALRKWKDELARLWKEQESEFVRSIGEEQTQPFTKSLSQLEYALEHDPTQANEHAQHAYDSWVVMADLRGKGKNN
SVPIGGHRLPPMPYSYNALEPYIDAKTMRLHHLKHHQTYVNDLNKAEKEMEKARRTGNYDLIKHWEREAAFNGAGHYLHT
LFWHVMSPNGGGEPQGLLKARITEDFGSFQKMKAHFSNAAEKVEGGGWAMLIYAPRSHRLEILQAEKHQNLSQQDQVPLL
VLDVWEHAYYLKYQNERKAYIEAWWNVVNWKEAENRYRQASQLKWVPY

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=197, Percent_Identity=43.6548223350254, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI67782305, Length=197, Percent_Identity=43.6548223350254, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI67782309, Length=197, Percent_Identity=36.0406091370558, Blast_Score=122, Evalue=4e-28,
Organism=Escherichia coli, GI1790342, Length=204, Percent_Identity=40.6862745098039, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1787946, Length=183, Percent_Identity=39.8907103825137, Blast_Score=143, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17506561, Length=197, Percent_Identity=40.1015228426396, Blast_Score=160, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI17569479, Length=196, Percent_Identity=39.7959183673469, Blast_Score=154, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6321796, Length=200, Percent_Identity=38, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17136812, Length=200, Percent_Identity=39.5, Blast_Score=160, Evalue=1e-39,

Paralogues:

None

Copy number: 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 33820; Mature: 33820

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSHEQALRKWKDELARLWKEQESEFVRSIGEEQTQPFTKSLSQLEYALEHDPTQANEHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHH
QHAYDSWVVMADLRGKGKNNSVPIGGHRLPPMPYSYNALEPYIDAKTMRLHHLKHHQTYV
HHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
NDLNKAEKEMEKARRTGNYDLIKHWEREAAFNGAGHYLHTLFWHVMSPNGGGEPQGLLKA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHH
RITEDFGSFQKMKAHFSNAAEKVEGGGWAMLIYAPRSHRLEILQAEKHQNLSQQDQVPLL
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCHHCCCCEE
VLDVWEHAYYLKYQNERKAYIEAWWNVVNWKEAENRYRQASQLKWVPY
EEEHHHHHEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDSHEQALRKWKDELARLWKEQESEFVRSIGEEQTQPFTKSLSQLEYALEHDPTQANEHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHH
QHAYDSWVVMADLRGKGKNNSVPIGGHRLPPMPYSYNALEPYIDAKTMRLHHLKHHQTYV
HHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
NDLNKAEKEMEKARRTGNYDLIKHWEREAAFNGAGHYLHTLFWHVMSPNGGGEPQGLLKA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHH
RITEDFGSFQKMKAHFSNAAEKVEGGGWAMLIYAPRSHRLEILQAEKHQNLSQQDQVPLL
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCHHCCCCEE
VLDVWEHAYYLKYQNERKAYIEAWWNVVNWKEAENRYRQASQLKWVPY
EEEHHHHHEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]