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The map label for this gene is fur [H]

Identifier: 56963545

GI number: 56963545

Start: 1900085

End: 1900576

Strand: Direct

Name: fur [H]

Synonym: ABC1780

Alternate gene names: 56963545

Gene position: 1900085-1900576 (Clockwise)

Preceding gene: 56963544

Following gene: 56963546

Centisome position: 44.15

GC content: 41.67

Gene sequence:

>492_bases
ATGGAAAATCGATTAGAGCGGATTAAAAAGCAAATGCATGCTCAGAGCTATAAATTAACGCCTCAGCGTGAAGCGACAGT
AATGGTTTTACTTGAACATGAAGAAGACCATTTAAGTGCTGAGGACGTCTACCTCCTTGTTAAAGAAAAAGCGCCTGAGA
TTGGTTTGGCGACGGTTTACCGTACACTAGAACTATTGACAGAACTCAATGTGGTTGACAAAATCAACTTCGGCGATGGC
GTTTCCCGTTTTGATTTGCGCAAAGAGGGAGCCAATCATTTTCACCACCATCTTGTTTGCATTGAGTGTGGCGCAGTTGA
TGAAATTACTGAGGATTTGCTTGGTGATGTCGAAGCGGTGGTAGAACGAGATTTTTCCTTTAAAATTAAAGATCATCGCT
TAACGTTCCACGGAATATGCTATCGTTGTCAAGAACAGCCTAGTCAAGAACAGCATAGCCAAGGCAGCAAACAATTAAAT
GAGCAAATGTAA

Upstream 100 bases:

>100_bases
TGATATTCATTTGCAGATTGGAATCATTATTAATTGACAACTGTTCTCTTCTCATTTATAATGAGTGTACATTTAGATCG
CTTTTGAGTAGGAGGCCGTT

Downstream 100 bases:

>100_bases
AAAAGGATTTTCTGCTAATGGAGCCCAGTACATAGAGGCTTCCGTTTAATCGGTCAATCGGCGCGCGGGTATTGTCCCTG
TCGGTTGGCCTTTTTTCGTG

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MENRLERIKKQMHAQSYKLTPQREATVMVLLEHEEDHLSAEDVYLLVKEKAPEIGLATVYRTLELLTELNVVDKINFGDG
VSRFDLRKEGANHFHHHLVCIECGAVDEITEDLLGDVEAVVERDFSFKIKDHRLTFHGICYRCQEQPSQEQHSQGSKQLN
EQM

Sequences:

>Translated_163_residues
MENRLERIKKQMHAQSYKLTPQREATVMVLLEHEEDHLSAEDVYLLVKEKAPEIGLATVYRTLELLTELNVVDKINFGDG
VSRFDLRKEGANHFHHHLVCIECGAVDEITEDLLGDVEAVVERDFSFKIKDHRLTFHGICYRCQEQPSQEQHSQGSKQLN
EQM
>Mature_163_residues
MENRLERIKKQMHAQSYKLTPQREATVMVLLEHEEDHLSAEDVYLLVKEKAPEIGLATVYRTLELLTELNVVDKINFGDG
VSRFDLRKEGANHFHHHLVCIECGAVDEITEDLLGDVEAVVERDFSFKIKDHRLTFHGICYRCQEQPSQEQHSQGSKQLN
EQM

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=123, Percent_Identity=34.9593495934959, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18887; Mature: 18887

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENRLERIKKQMHAQSYKLTPQREATVMVLLEHEEDHLSAEDVYLLVKEKAPEIGLATVY
CCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHH
RTLELLTELNVVDKINFGDGVSRFDLRKEGANHFHHHLVCIECGAVDEITEDLLGDVEAV
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHEEEEEECCCHHHHHHHHHHHHHHH
VERDFSFKIKDHRLTFHGICYRCQEQPSQEQHSQGSKQLNEQM
HHCCCCEEEECCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENRLERIKKQMHAQSYKLTPQREATVMVLLEHEEDHLSAEDVYLLVKEKAPEIGLATVY
CCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHH
RTLELLTELNVVDKINFGDGVSRFDLRKEGANHFHHHLVCIECGAVDEITEDLLGDVEAV
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHEEEEEECCCHHHHHHHHHHHHHHH
VERDFSFKIKDHRLTFHGICYRCQEQPSQEQHSQGSKQLNEQM
HHCCCCEEEECCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]