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The map label for this gene is crr [H]

Identifier: 56963538

GI number: 56963538

Start: 1894467

End: 1894964

Strand: Direct

Name: crr [H]

Synonym: ABC1773

Alternate gene names: 56963538

Gene position: 1894467-1894964 (Clockwise)

Preceding gene: 56963536

Following gene: 56963539

Centisome position: 44.02

GC content: 45.78

Gene sequence:

>498_bases
ATGTTTAAAAAACTATTTGGAAAGAAAGAGACAGCGCCAGCGGAGGAAACCATTACCGCGCCGGTGAATGGAAAAGTTGT
CCCAATAGAAGAAGTGCCTGACCCAACATTCGGTCAAAAAATGATTGGCGATGGATTGGCTGTTGAGCCGACGGATGGGC
ATATTGTCGCGCCTGTTAGTGGAAAGATTGTCCAAGTGTTTCCGACAAAGCACGCTTTTGGAATTGAAACGGCATCTGGG
GCAGAATTGCTCATCCATATTGGCCTTGAAACAGTGGCGATGAATGGAGAAGGATTTACTGCCCATGTAAAAGAAGGCGA
TACCATTTCCGTCGGCGACCCGATCATTGACTTTGACGTAGAGCTTGTCAAAGAAAAAGCTGCGCACACGATTACGCCAG
TTGTGCTAACCAACCCAGATCGTTATTCGCTTGAAAAACAACAAAACAGCGAAGCGATGGCTGGAAAAACAGCGCTTTTT
ACAATAAGAGCCAAATAA

Upstream 100 bases:

>100_bases
GGAAAGGAAGAGTGAGTCGAAATTTGACAGGGTGCAAACAGGATTATTACAATAATAAATGAGATGAGTGTGACGCTTAT
CGACAGTAAGGAGTGGTCAT

Downstream 100 bases:

>100_bases
TAGGGAAGAAACGCGTGGGCGCTTAGAGTCTGCGCGTTTTTTTATACTAGACTTTCCAGCTGTTTTAGGCATATTTTAGC
TAGCGTTCGCCAAAGGAACC

Product: PTS system, glucose-specific enzyme II, A component

Products: Protein Histidine; Sugar Phosphate.; glucose-6-phosphate [Cytoplasm]; pyruvate; alpha,alpha-trehalose 6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIA-Glc; EIII-Glc; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MFKKLFGKKETAPAEETITAPVNGKVVPIEEVPDPTFGQKMIGDGLAVEPTDGHIVAPVSGKIVQVFPTKHAFGIETASG
AELLIHIGLETVAMNGEGFTAHVKEGDTISVGDPIIDFDVELVKEKAAHTITPVVLTNPDRYSLEKQQNSEAMAGKTALF
TIRAK

Sequences:

>Translated_165_residues
MFKKLFGKKETAPAEETITAPVNGKVVPIEEVPDPTFGQKMIGDGLAVEPTDGHIVAPVSGKIVQVFPTKHAFGIETASG
AELLIHIGLETVAMNGEGFTAHVKEGDTISVGDPIIDFDVELVKEKAAHTITPVVLTNPDRYSLEKQQNSEAMAGKTALF
TIRAK
>Mature_165_residues
MFKKLFGKKETAPAEETITAPVNGKVVPIEEVPDPTFGQKMIGDGLAVEPTDGHIVAPVSGKIVQVFPTKHAFGIETASG
AELLIHIGLETVAMNGEGFTAHVKEGDTISVGDPIIDFDVELVKEKAAHTITPVVLTNPDRYSLEKQQNSEAMAGKTALF
TIRAK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG2190

COG function: function code G; Phosphotransferase system IIA components

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788757, Length=156, Percent_Identity=44.2307692307692, Blast_Score=138, Evalue=2e-34,
Organism=Escherichia coli, GI1786894, Length=147, Percent_Identity=42.1768707482993, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1790159, Length=154, Percent_Identity=37.6623376623377, Blast_Score=122, Evalue=1e-29,

Paralogues:

None

Copy number: 3540 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 140 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR001127 [H]

Pfam domain/function: PF00358 PTS_EIIA_1 [H]

EC number: 2.7.1.69 [C]

Molecular weight: Translated: 17591; Mature: 17591

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKLFGKKETAPAEETITAPVNGKVVPIEEVPDPTFGQKMIGDGLAVEPTDGHIVAPVS
CCHHHCCCCCCCCCCCEEECCCCCEEEEHHCCCCCCCCHHHHCCCCEECCCCCEEECCCC
GKIVQVFPTKHAFGIETASGAELLIHIGLETVAMNGEGFTAHVKEGDTISVGDPIIDFDV
CCEEEEEECCCCCCEECCCCCEEEEEECEEEEEECCCCEEEEECCCCEEECCCCEEECCH
ELVKEKAAHTITPVVLTNPDRYSLEKQQNSEAMAGKTALFTIRAK
HHHHHHHCCEECEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEC
>Mature Secondary Structure
MFKKLFGKKETAPAEETITAPVNGKVVPIEEVPDPTFGQKMIGDGLAVEPTDGHIVAPVS
CCHHHCCCCCCCCCCCEEECCCCCEEEEHHCCCCCCCCHHHHCCCCEECCCCCEEECCCC
GKIVQVFPTKHAFGIETASGAELLIHIGLETVAMNGEGFTAHVKEGDTISVGDPIIDFDV
CCEEEEEECCCCCCEECCCCCEEEEEECEEEEEECCCCEEEEECCCCEEECCCCEEECCH
ELVKEKAAHTITPVVLTNPDRYSLEKQQNSEAMAGKTALFTIRAK
HHHHHHHCCEECEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Protein N-Phosphohistidine; Sugar; phosphoenolpyruvate; beta-D-glucose [Periplasm]; phosphoenolpyruvate; trehalose [Periplasm] [C]

Specific reaction: Protein N-Phosphohistidine + Sugar = Protein Histidine + Sugar Phosphate. phosphoenolpyruvate + beta-D-glucose [Periplasm] = glucose-6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + trehalose [Periplasm] = alpha,alpha-trehalose 6-phosphate [Cytop

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]