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The map label for this gene is adcB [H]

Identifier: 56963468

GI number: 56963468

Start: 1831171

End: 1832046

Strand: Direct

Name: adcB [H]

Synonym: ABC1703

Alternate gene names: 56963468

Gene position: 1831171-1832046 (Clockwise)

Preceding gene: 56963467

Following gene: 56963469

Centisome position: 42.55

GC content: 42.92

Gene sequence:

>876_bases
ATGTTTAGCGCGTTCTTGACTTATGATTTTTTACGATATGCTTTTTTTACAGGGATGCTCATCGGTGTGTTAGCCCCACT
TCTAGGAGTATTTCTAGTGGTCAGGCGGATGTCGCTCATCGCTGACGCTCTATCACATATCACCCTTTCAGGAATTACAT
TTAGCTTATTGCTTGGCAGTTACTTTCCGTTTATGAGCGGGGCGAACCCTCTTTACTTAGGAATGGCATTTTCTGTAGGC
GGGTCCCTTTTTATTGAGAAACTTCGCCAAGTATACGTCCATTACAAAGAAATCGCGATTCCAATTATCATGTCTGCTGG
GATTGGTCTTGGGGTTATTTTTATTTCTTTGGCCAATGGCTTTAACAATGACTTGCTCAATTATTTGTTTGGTTCAGTCA
TTGCCGTCAATCGCAGTGACTTTATTACGATCACGATCATAACGGTTGTCGTTTTTGTTGTGCTGATCCTTTTTTATAAA
GAATTGTTCTTTTTGTCGTTTGATGAGGAGCAAGCAATTGTTTCAGGAATTAACCGGCACCTGGTCCATCTCGTGTTTAT
GGTAATGGTTGCCCTTGTGATTGCCGCTTCGATGCGGGTTGTGGGGATTCTGCTTGTTTCCTCGCTTATGACACTGCCTG
TTGCGAGCGCCATGCGTTTTGCTAAAGGGTTTAAACAATTGTTTGTGTTTGCTGTTGCCTTTGGCGAAATGGCCGTGATT
GGCGGTTTAATTGCTGCTTACCAACTGCAAATAGCACCAGGTGGGGCGATTGTCATGATTGCTGTCATCATTTTGCTTTT
GTCACTAGCATTTGGGCGAAATCGCAAAAAAGGCTTATTCTTATTCGGTAGGGGAAACACACCTAGTCAAGCTTAA

Upstream 100 bases:

>100_bases
TTTCATGGGACGTCAGATGAATTTGTTGCCAAAAACGATAAACTTGAATTTTATGGGCATGACGTTCAACTTCTAACCCA
TAACCATGAAGGAGTTGCCC

Downstream 100 bases:

>100_bases
AAAAATCCGTTAAACTAAAAGAAAGTCTAAAAAGAGGGTCGATTGCATGGATGTATCAACTGCACTTAATCGTCTAAAAG
AAGAAGGGTATAAGTATACG

Product: metal ion ABC transporter permease

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MFSAFLTYDFLRYAFFTGMLIGVLAPLLGVFLVVRRMSLIADALSHITLSGITFSLLLGSYFPFMSGANPLYLGMAFSVG
GSLFIEKLRQVYVHYKEIAIPIIMSAGIGLGVIFISLANGFNNDLLNYLFGSVIAVNRSDFITITIITVVVFVVLILFYK
ELFFLSFDEEQAIVSGINRHLVHLVFMVMVALVIAASMRVVGILLVSSLMTLPVASAMRFAKGFKQLFVFAVAFGEMAVI
GGLIAAYQLQIAPGGAIVMIAVIILLLSLAFGRNRKKGLFLFGRGNTPSQA

Sequences:

>Translated_291_residues
MFSAFLTYDFLRYAFFTGMLIGVLAPLLGVFLVVRRMSLIADALSHITLSGITFSLLLGSYFPFMSGANPLYLGMAFSVG
GSLFIEKLRQVYVHYKEIAIPIIMSAGIGLGVIFISLANGFNNDLLNYLFGSVIAVNRSDFITITIITVVVFVVLILFYK
ELFFLSFDEEQAIVSGINRHLVHLVFMVMVALVIAASMRVVGILLVSSLMTLPVASAMRFAKGFKQLFVFAVAFGEMAVI
GGLIAAYQLQIAPGGAIVMIAVIILLLSLAFGRNRKKGLFLFGRGNTPSQA
>Mature_291_residues
MFSAFLTYDFLRYAFFTGMLIGVLAPLLGVFLVVRRMSLIADALSHITLSGITFSLLLGSYFPFMSGANPLYLGMAFSVG
GSLFIEKLRQVYVHYKEIAIPIIMSAGIGLGVIFISLANGFNNDLLNYLFGSVIAVNRSDFITITIITVVVFVVLILFYK
ELFFLSFDEEQAIVSGINRHLVHLVFMVMVALVIAASMRVVGILLVSSLMTLPVASAMRFAKGFKQLFVFAVAFGEMAVI
GGLIAAYQLQIAPGGAIVMIAVIILLLSLAFGRNRKKGLFLFGRGNTPSQA

Specific function: Part of the high-affinity ABC transporter complex AdcABC involved in zinc import (Probable). Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=258, Percent_Identity=32.5581395348837, Blast_Score=129, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 31671; Mature: 31671

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSAFLTYDFLRYAFFTGMLIGVLAPLLGVFLVVRRMSLIADALSHITLSGITFSLLLGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFPFMSGANPLYLGMAFSVGGSLFIEKLRQVYVHYKEIAIPIIMSAGIGLGVIFISLANG
HHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
FNNDLLNYLFGSVIAVNRSDFITITIITVVVFVVLILFYKELFFLSFDEEQAIVSGINRH
CCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LVHLVFMVMVALVIAASMRVVGILLVSSLMTLPVASAMRFAKGFKQLFVFAVAFGEMAVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGLIAAYQLQIAPGGAIVMIAVIILLLSLAFGRNRKKGLFLFGRGNTPSQA
HHHHHHHHEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MFSAFLTYDFLRYAFFTGMLIGVLAPLLGVFLVVRRMSLIADALSHITLSGITFSLLLGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFPFMSGANPLYLGMAFSVGGSLFIEKLRQVYVHYKEIAIPIIMSAGIGLGVIFISLANG
HHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
FNNDLLNYLFGSVIAVNRSDFITITIITVVVFVVLILFYKELFFLSFDEEQAIVSGINRH
CCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LVHLVFMVMVALVIAASMRVVGILLVSSLMTLPVASAMRFAKGFKQLFVFAVAFGEMAVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGLIAAYQLQIAPGGAIVMIAVIILLLSLAFGRNRKKGLFLFGRGNTPSQA
HHHHHHHHEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377 [H]