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The map label for this gene is pheA [H]

Identifier: 56963309

GI number: 56963309

Start: 1667399

End: 1668274

Strand: Direct

Name: pheA [H]

Synonym: ABC1544

Alternate gene names: 56963309

Gene position: 1667399-1668274 (Clockwise)

Preceding gene: 56963308

Following gene: 56963312

Centisome position: 38.74

GC content: 45.89

Gene sequence:

>876_bases
GTGAAAAAAGTCGGTTTTTTAGGCCCGAAAGGCACGTTTACGGAAATGGCAGCATACAGCCTGTTTCCGAAAGAAGAATT
AGTTCCACTGAAAACCATCCCAAAAGTGCTCGATCTCGCATTTGCAAAAGGGATTGACTATGCAGTTGTGCCAATTGAAA
ATGCGATTGAAGGAACTGTGAATATTACGCTCGATTATTTAATCCACCATAAGCCCATGCCGATTGTAGCAAGCATATCT
CTGGAAATCGCGCAACATTTGCTGTTTTCGCCAAACAAAGACCGGGAAACGTTCGTTCCGAAGAAAGTCGTTTCCCATCC
ACAAGCAATTGCCCAGTGCCACCAATTTCTGCAAAAAAACTATCCTGAAATTGAAATCGAGTATGCCGATTCAACTGGTT
CGGCTGCCGCTTGGCTCGCTGAAAACCCCAATGCAGATGCTTGTGTCATTGCCAACGCGCAAGCGGCTTCGACTTATGGA
TTAGCTGTAGCTCAAGGAGACATCCATGATTTCGAACATAACCGGACGCGCTTTATCGTGCTAACGGCCAAAAAGGAACA
AGCTCCTCACATAGTAGGCCCAGAGCATACAGGAGACAAAACAACATTGATGGTAACGCTGCCGTCTGATTTTGCTGGAG
CCCTCCATCAAGTGTTGTCCGCTTTTGCTTGGCGAAAGTTGAATTTGTCCAAAATCGAATCACGCCCAACAAAAACCGGC
CTCGGAAATTACTTTTTCCTGATTGACATCGACCAGTTAATGGATGACGTCCTAGTGCCAGGAGCGATTGCTGAGCTTAC
TGCACTTGGCTGTAAAGTTGAAGTCCTTGGCAGCTATGCGACATACAGTTCAAAGGCGACAGCATCGATTAATTAA

Upstream 100 bases:

>100_bases
TGAAATAGACATAAACGAACTGTTTGAACGGATGGAGGCGCTTGAGTCTGTTGAACGGGTGGAACTAGTTGGTTCAGGAT
CATAGAAAGGAAGCGTTTTT

Downstream 100 bases:

>100_bases
GAAGAGTAGCGCCTAGCTACTCTTCTAACAAAAACGACTTTTCTCGGAGCGCGGCGATCGCCTTTTCCACTTGTGCTTCG
TTTTGTCCTTCTACTAAATG

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKKVGFLGPKGTFTEMAAYSLFPKEELVPLKTIPKVLDLAFAKGIDYAVVPIENAIEGTVNITLDYLIHHKPMPIVASIS
LEIAQHLLFSPNKDRETFVPKKVVSHPQAIAQCHQFLQKNYPEIEIEYADSTGSAAAWLAENPNADACVIANAQAASTYG
LAVAQGDIHDFEHNRTRFIVLTAKKEQAPHIVGPEHTGDKTTLMVTLPSDFAGALHQVLSAFAWRKLNLSKIESRPTKTG
LGNYFFLIDIDQLMDDVLVPGAIAELTALGCKVEVLGSYATYSSKATASIN

Sequences:

>Translated_291_residues
MKKVGFLGPKGTFTEMAAYSLFPKEELVPLKTIPKVLDLAFAKGIDYAVVPIENAIEGTVNITLDYLIHHKPMPIVASIS
LEIAQHLLFSPNKDRETFVPKKVVSHPQAIAQCHQFLQKNYPEIEIEYADSTGSAAAWLAENPNADACVIANAQAASTYG
LAVAQGDIHDFEHNRTRFIVLTAKKEQAPHIVGPEHTGDKTTLMVTLPSDFAGALHQVLSAFAWRKLNLSKIESRPTKTG
LGNYFFLIDIDQLMDDVLVPGAIAELTALGCKVEVLGSYATYSSKATASIN
>Mature_291_residues
MKKVGFLGPKGTFTEMAAYSLFPKEELVPLKTIPKVLDLAFAKGIDYAVVPIENAIEGTVNITLDYLIHHKPMPIVASIS
LEIAQHLLFSPNKDRETFVPKKVVSHPQAIAQCHQFLQKNYPEIEIEYADSTGSAAAWLAENPNADACVIANAQAASTYG
LAVAQGDIHDFEHNRTRFIVLTAKKEQAPHIVGPEHTGDKTTLMVTLPSDFAGALHQVLSAFAWRKLNLSKIESRPTKTG
LGNYFFLIDIDQLMDDVLVPGAIAELTALGCKVEVLGSYATYSSKATASIN

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=281, Percent_Identity=30.9608540925267, Blast_Score=118, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6324013, Length=273, Percent_Identity=28.9377289377289, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF00800 PDT [H]

EC number: =4.2.1.51 [H]

Molecular weight: Translated: 31690; Mature: 31690

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVGFLGPKGTFTEMAAYSLFPKEELVPLKTIPKVLDLAFAKGIDYAVVPIENAIEGTV
CCCCCCCCCCCCHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCEE
NITLDYLIHHKPMPIVASISLEIAQHLLFSPNKDRETFVPKKVVSHPQAIAQCHQFLQKN
EEEEEEEEECCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHCC
YPEIEIEYADSTGSAAAWLAENPNADACVIANAQAASTYGLAVAQGDIHDFEHNRTRFIV
CCEEEEEECCCCCCEEEEEECCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCCEEEEE
LTAKKEQAPHIVGPEHTGDKTTLMVTLPSDFAGALHQVLSAFAWRKLNLSKIESRPTKTG
EEECCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCC
LGNYFFLIDIDQLMDDVLVPGAIAELTALGCKVEVLGSYATYSSKATASIN
CCCEEEEEEHHHHHHHHCCCCHHHHHHHHCCEEEEEECCCCCCCCEEEECC
>Mature Secondary Structure
MKKVGFLGPKGTFTEMAAYSLFPKEELVPLKTIPKVLDLAFAKGIDYAVVPIENAIEGTV
CCCCCCCCCCCCHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCEE
NITLDYLIHHKPMPIVASISLEIAQHLLFSPNKDRETFVPKKVVSHPQAIAQCHQFLQKN
EEEEEEEEECCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHCC
YPEIEIEYADSTGSAAAWLAENPNADACVIANAQAASTYGLAVAQGDIHDFEHNRTRFIV
CCEEEEEECCCCCCEEEEEECCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCCEEEEE
LTAKKEQAPHIVGPEHTGDKTTLMVTLPSDFAGALHQVLSAFAWRKLNLSKIESRPTKTG
EEECCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCC
LGNYFFLIDIDQLMDDVLVPGAIAELTALGCKVEVLGSYATYSSKATASIN
CCCEEEEEEHHHHHHHHCCCCHHHHHHHHCCEEEEEECCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2537815; 9384377; 8444804 [H]