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The map label for this gene is yhcG [H]

Identifier: 56963226

GI number: 56963226

Start: 1579992

End: 1580690

Strand: Direct

Name: yhcG [H]

Synonym: ABC1461

Alternate gene names: 56963226

Gene position: 1579992-1580690 (Clockwise)

Preceding gene: 56963225

Following gene: 56963227

Centisome position: 36.71

GC content: 44.49

Gene sequence:

>699_bases
ATGAGTGCACTAGTGGTCGAATCACTGGAAAAAAAATATGGCCGAAAGCGTGTTTTTGCAAATTTATCAGTAGAGATGAC
AAAAAATCGCTTTATCGTACTTCTAGGCGCAAATGGTGCAGGCAAAACGACATTTTTAAAAGTGTGTGCAGGACTTGCGC
CAGCTGGAAAGGGCCGTATCTCCCTCGATGGCGAGCATAAGCGAGCAGCGCGTGTTCAATTAGCCAGTTATGTCTCAGAA
GAGGGTGGTTTCGAGCCCCATAAACGGGTAAAAACGATTTTGCATGACCAAAAAGCGGTTTACGAGACGTTCCAGCATCA
CCGTGCGTTAGAAATGTGCAAAACCGCCGGATTGGAAGAAGGGACTAAATGGGGGGCGCTTTCAAAAGGGCAGCAACACT
TGCTCTCGTTAATCGTTGCCCTTGCTAAGCCGAAGCCTTTTATTTTTATTGACGAATTGCTCGCTAATCTTGATACAGCA
AAAAAAGAGGCGATGATTGCTGTGTTAACAGATTTTCTAGTGGAAGAAGAACGGATGATTATCATGGCGACCCATGCGTA
TGAAGATGTAGAAATGCTTGCTGATGGTGTCATTTTTTTACGCGAGGATGAAGCAGATGTTATTACTGATTTAGAGGAAT
GGCGCTTAGAGAAAGGACAGTCCCTCAAGGATTTGTTTGCAGAGGTGGGCAAAAAATGA

Upstream 100 bases:

>100_bases
CGCAGATGCAAGCGTTAATTACATTCATGAGAAAGCTCGGTTTTTCCAATCAAGAAATTAGCGCCTCTTTAGAACGGTCA
TTAAAGGAGATGGGAAACCC

Downstream 100 bases:

>100_bases
ACGTATTTTGGTTCTATCTGAAACGTAATTTCTTTATGTTGCTTCCTGTGAACACGATCATTTTTTTGCTTTTGTTCACT
GGTGTGATTCTTCTAAAAGC

Product: multidrug ABC transporter ATP-binding protein

Products: taurine [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSALVVESLEKKYGRKRVFANLSVEMTKNRFIVLLGANGAGKTTFLKVCAGLAPAGKGRISLDGEHKRAARVQLASYVSE
EGGFEPHKRVKTILHDQKAVYETFQHHRALEMCKTAGLEEGTKWGALSKGQQHLLSLIVALAKPKPFIFIDELLANLDTA
KKEAMIAVLTDFLVEEERMIIMATHAYEDVEMLADGVIFLREDEADVITDLEEWRLEKGQSLKDLFAEVGKK

Sequences:

>Translated_232_residues
MSALVVESLEKKYGRKRVFANLSVEMTKNRFIVLLGANGAGKTTFLKVCAGLAPAGKGRISLDGEHKRAARVQLASYVSE
EGGFEPHKRVKTILHDQKAVYETFQHHRALEMCKTAGLEEGTKWGALSKGQQHLLSLIVALAKPKPFIFIDELLANLDTA
KKEAMIAVLTDFLVEEERMIIMATHAYEDVEMLADGVIFLREDEADVITDLEEWRLEKGQSLKDLFAEVGKK
>Mature_231_residues
SALVVESLEKKYGRKRVFANLSVEMTKNRFIVLLGANGAGKTTFLKVCAGLAPAGKGRISLDGEHKRAARVQLASYVSEE
GGFEPHKRVKTILHDQKAVYETFQHHRALEMCKTAGLEEGTKWGALSKGQQHLLSLIVALAKPKPFIFIDELLANLDTAK
KEAMIAVLTDFLVEEERMIIMATHAYEDVEMLADGVIFLREDEADVITDLEEWRLEKGQSLKDLFAEVGKK

Specific function: Part Of A Binding-Protein-Dependent Transport System For Taurine. Probably Responsible For Energy Coupling To The Transport System. [C]

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1786563, Length=214, Percent_Identity=27.1028037383178, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786319, Length=214, Percent_Identity=27.5700934579439, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081709, Length=207, Percent_Identity=26.0869565217391, Blast_Score=60, Evalue=1e-10,
Organism=Drosophila melanogaster, GI116007328, Length=226, Percent_Identity=25.2212389380531, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24666092, Length=225, Percent_Identity=25.3333333333333, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574150, Length=207, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 25857; Mature: 25726

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALVVESLEKKYGRKRVFANLSVEMTKNRFIVLLGANGAGKTTFLKVCAGLAPAGKGRI
CCHHHHHHHHHHHCHHHHHHCCEEEEECCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCE
SLDGEHKRAARVQLASYVSEEGGFEPHKRVKTILHDQKAVYETFQHHRALEMCKTAGLEE
EECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GTKWGALSKGQQHLLSLIVALAKPKPFIFIDELLANLDTAKKEAMIAVLTDFLVEEERMI
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IMATHAYEDVEMLADGVIFLREDEADVITDLEEWRLEKGQSLKDLFAEVGKK
EEEECCHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure 
SALVVESLEKKYGRKRVFANLSVEMTKNRFIVLLGANGAGKTTFLKVCAGLAPAGKGRI
CHHHHHHHHHHHCHHHHHHCCEEEEECCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCE
SLDGEHKRAARVQLASYVSEEGGFEPHKRVKTILHDQKAVYETFQHHRALEMCKTAGLEE
EECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GTKWGALSKGQQHLLSLIVALAKPKPFIFIDELLANLDTAKKEAMIAVLTDFLVEEERMI
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IMATHAYEDVEMLADGVIFLREDEADVITDLEEWRLEKGQSLKDLFAEVGKK
EEEECCHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: taurine [Periplasm]; ATP; H2O [C]

Specific reaction: taurine [Periplasm] + ATP + H2O = taurine [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]