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The map label for this gene is mtlR [H]

Identifier: 56963173

GI number: 56963173

Start: 1521989

End: 1523836

Strand: Direct

Name: mtlR [H]

Synonym: ABC1406

Alternate gene names: 56963173

Gene position: 1521989-1523836 (Clockwise)

Preceding gene: 56963172

Following gene: 56963174

Centisome position: 35.36

GC content: 40.21

Gene sequence:

>1848_bases
ATGCTAAGCGCAAGGGAATTTCATTTAACAAATAAGCTGTTGAATACGAAAGCTCCGATTAGAATCAAAGATTTGTCAAT
CGAGTTTGGGGTGAGCACAAGAGCGATTAAGTATGACCTTGAAAATGTTCGCAAATGGTTTAAGTTGCAGGGGAAGACGG
TGAATTCCCAGACAAGCAAGGGGATTTGGCTTCAATGCAGTGATCGGGAGCGGACTGAATTAAGGGGGATTTTGACACAA
TTTAAGCGATCGCAAATTTACCCCGATCAAACGATGCGTGTCAGAAGGATTATTCTGTCCCTATTATGGACGAATGATTA
TAAAACCGCTGCTCAATTATCGGAGATGCTAGCGGTCAGCAGAAACACGATTTTAAGCGATTTGAATCATGTAGACGAGT
TTTTAACGTCATGGAATATTGAGTTGGAGCGGAAGCAAAGAACAGGGTATCGCCTTCATGGCAATGAACTTCAGCTGCGG
CTGATGCTTGAGCATATTATTTACAACAGCTTAGATGATTATCAAATCTATAAGCTAACGACTCGAATTACGAAAAAAGA
GCGGCAAATCGAGATTGGCACGATATTGGAAGAGCCATTAAAACCTATTTATGAAATGGCTGAAAATCATATGAGCGCGT
TCTATTCGCCATCCTTGGCATCTTTGTTGCGGCTCTCTGATTTGTTGAAATTCCTACTGCGGCTCACGTTTTCGGTGAAA
AGATTAACGATGGGGCGTGCCATTCATAGCTATCGGATGTTGCAGCCTTCTCATGATCAAGATGAACTCTCCTTGTTTCT
GGTGAACGTTATGGAGAAAGTCTACACAGATATGCAGTTGCCGTTGCTCGAGGAAGAATACGCGTATGTAGCCGGAATCA
TGGAAAAAGAATCTGAACAAATCGATGTAGTCGATATCACAGAGAAGATGATCCAGTATGTAAGCGAACAAGAAAGAATT
GACTATAAAAAAGACCCTAAACTTTATAGCAATCTGCTCTCTCATTTGTCACTGAGGCTTCAAAATGGCTCATTTTATTT
AAATGAAATGAACCCAATGGAGGACGAAGTGAAAAGAAACCATGCGTCTCTTTTTCAAAGCGTCAAGGAATCTTGTCGAA
AGTATGTGAAACAACACACATTGATAGCCCAAGATTCTTTTATCTCTTTTATTGTTCTGCACTTCCTCGTTTCCTATGAA
AATACATTTAAACGAAAAAAGAAAGTAAAAGTTTTATATGTATGTTCAACAGGAAGAGGGGTTGCCCGGTTAATCAAAAA
TCGGGTAGAAAAAGAAATTCCTGCCGTCGATATTGTCTGTTATTGTTCCTTGCTTGAAGTGGAAGAGATTTGTCAGGCTG
AAGAGGTGGATTTGATTATCAGCGTTTTTCCTGTTGAAGCCGCCGTTCCTGTTGTCGTTGTCGAGCCGCTGCCTGCAAAA
AGAGATATTGAAGAAATTCGCAAACAAGTACGAGCGATGATCGGTTCAGACGACGAGCAGACGAACGAGCTGTTGGAGAA
CAATGAGTTTACGATCAGTGAAGATAGTGAGAACCTCAGCCAGGAAATTATTTTAAAAGGCTTTGAAGCTGCTCATGCAT
TATTGGAAGCCTTTCCAATTAAATCAGAAGAACGATGGAAAAATGCGTTTATGATGCACGTCTTTTTAATGGTTCACCGC
TATTACTTTGATAAGCAATATGACCAGTACCTCTATGCAAATAATCAAATGCTAGACAGCGACGAGGAAATGTTCCATAG
CGTGCAGCAAATTTTACAGGATAAAGATTTACATGTTCATGAAGCTGAGGTTATTACTCTTTTACAGTACTTGAAAAAAT
GGAAGTGA

Upstream 100 bases:

>100_bases
AGGATGGGGAAGTAATTTTGTCTGTCCGATCTAGGTAAATGTACTTATAATTGATCTATAATCGATTATGAATCACGACT
ACTAGTAGAGTGGTGAAATC

Downstream 100 bases:

>100_bases
TTATATGATTCAAGGCATTATTATCCAGAACGGCTTCGTGATTGACCCGGAAACTTTAACGATTAGCAAAAAAGAGATTG
GCATCGTCAATGGTGTTTTT

Product: BglG family transcriptional antiterminator

Products: NA

Alternate protein names: Mannitol operon transcriptional activator; Mtl operon transcriptional activator; Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MLSAREFHLTNKLLNTKAPIRIKDLSIEFGVSTRAIKYDLENVRKWFKLQGKTVNSQTSKGIWLQCSDRERTELRGILTQ
FKRSQIYPDQTMRVRRIILSLLWTNDYKTAAQLSEMLAVSRNTILSDLNHVDEFLTSWNIELERKQRTGYRLHGNELQLR
LMLEHIIYNSLDDYQIYKLTTRITKKERQIEIGTILEEPLKPIYEMAENHMSAFYSPSLASLLRLSDLLKFLLRLTFSVK
RLTMGRAIHSYRMLQPSHDQDELSLFLVNVMEKVYTDMQLPLLEEEYAYVAGIMEKESEQIDVVDITEKMIQYVSEQERI
DYKKDPKLYSNLLSHLSLRLQNGSFYLNEMNPMEDEVKRNHASLFQSVKESCRKYVKQHTLIAQDSFISFIVLHFLVSYE
NTFKRKKKVKVLYVCSTGRGVARLIKNRVEKEIPAVDIVCYCSLLEVEEICQAEEVDLIISVFPVEAAVPVVVVEPLPAK
RDIEEIRKQVRAMIGSDDEQTNELLENNEFTISEDSENLSQEIILKGFEAAHALLEAFPIKSEERWKNAFMMHVFLMVHR
YYFDKQYDQYLYANNQMLDSDEEMFHSVQQILQDKDLHVHEAEVITLLQYLKKWK

Sequences:

>Translated_615_residues
MLSAREFHLTNKLLNTKAPIRIKDLSIEFGVSTRAIKYDLENVRKWFKLQGKTVNSQTSKGIWLQCSDRERTELRGILTQ
FKRSQIYPDQTMRVRRIILSLLWTNDYKTAAQLSEMLAVSRNTILSDLNHVDEFLTSWNIELERKQRTGYRLHGNELQLR
LMLEHIIYNSLDDYQIYKLTTRITKKERQIEIGTILEEPLKPIYEMAENHMSAFYSPSLASLLRLSDLLKFLLRLTFSVK
RLTMGRAIHSYRMLQPSHDQDELSLFLVNVMEKVYTDMQLPLLEEEYAYVAGIMEKESEQIDVVDITEKMIQYVSEQERI
DYKKDPKLYSNLLSHLSLRLQNGSFYLNEMNPMEDEVKRNHASLFQSVKESCRKYVKQHTLIAQDSFISFIVLHFLVSYE
NTFKRKKKVKVLYVCSTGRGVARLIKNRVEKEIPAVDIVCYCSLLEVEEICQAEEVDLIISVFPVEAAVPVVVVEPLPAK
RDIEEIRKQVRAMIGSDDEQTNELLENNEFTISEDSENLSQEIILKGFEAAHALLEAFPIKSEERWKNAFMMHVFLMVHR
YYFDKQYDQYLYANNQMLDSDEEMFHSVQQILQDKDLHVHEAEVITLLQYLKKWK
>Mature_615_residues
MLSAREFHLTNKLLNTKAPIRIKDLSIEFGVSTRAIKYDLENVRKWFKLQGKTVNSQTSKGIWLQCSDRERTELRGILTQ
FKRSQIYPDQTMRVRRIILSLLWTNDYKTAAQLSEMLAVSRNTILSDLNHVDEFLTSWNIELERKQRTGYRLHGNELQLR
LMLEHIIYNSLDDYQIYKLTTRITKKERQIEIGTILEEPLKPIYEMAENHMSAFYSPSLASLLRLSDLLKFLLRLTFSVK
RLTMGRAIHSYRMLQPSHDQDELSLFLVNVMEKVYTDMQLPLLEEEYAYVAGIMEKESEQIDVVDITEKMIQYVSEQERI
DYKKDPKLYSNLLSHLSLRLQNGSFYLNEMNPMEDEVKRNHASLFQSVKESCRKYVKQHTLIAQDSFISFIVLHFLVSYE
NTFKRKKKVKVLYVCSTGRGVARLIKNRVEKEIPAVDIVCYCSLLEVEEICQAEEVDLIISVFPVEAAVPVVVVEPLPAK
RDIEEIRKQVRAMIGSDDEQTNELLENNEFTISEDSENLSQEIILKGFEAAHALLEAFPIKSEERWKNAFMMHVFLMVHR
YYFDKQYDQYLYANNQMLDSDEEMFHSVQQILQDKDLHVHEAEVITLLQYLKKWK

Specific function: Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 72353; Mature: 72353

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSAREFHLTNKLLNTKAPIRIKDLSIEFGVSTRAIKYDLENVRKWFKLQGKTVNSQTSK
CCCCHHHHHHHHHHCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEECCCCCC
GIWLQCSDRERTELRGILTQFKRSQIYPDQTMRVRRIILSLLWTNDYKTAAQLSEMLAVS
CEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RNTILSDLNHVDEFLTSWNIELERKQRTGYRLHGNELQLRLMLEHIIYNSLDDYQIYKLT
HHHHHHHHHHHHHHHHHCCCEEEECCCCCCEECCCHHHHHHHHHHHHHCCCCCCHHHHHH
TRITKKERQIEIGTILEEPLKPIYEMAENHMSAFYSPSLASLLRLSDLLKFLLRLTFSVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RLTMGRAIHSYRMLQPSHDQDELSLFLVNVMEKVYTDMQLPLLEEEYAYVAGIMEKESEQ
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
IDVVDITEKMIQYVSEQERIDYKKDPKLYSNLLSHLSLRLQNGSFYLNEMNPMEDEVKRN
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEECCCEEECCCCCCHHHHHHH
HASLFQSVKESCRKYVKQHTLIAQDSFISFIVLHFLVSYENTFKRKKKVKVLYVCSTGRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCH
VARLIKNRVEKEIPAVDIVCYCSLLEVEEICQAEEVDLIISVFPVEAAVPVVVVEPLPAK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCEEEECCCCCC
RDIEEIRKQVRAMIGSDDEQTNELLENNEFTISEDSENLSQEIILKGFEAAHALLEAFPI
CCHHHHHHHHHHHHCCCCHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
KSEERWKNAFMMHVFLMVHRYYFDKQYDQYLYANNQMLDSDEEMFHSVQQILQDKDLHVH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCH
EAEVITLLQYLKKWK
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSAREFHLTNKLLNTKAPIRIKDLSIEFGVSTRAIKYDLENVRKWFKLQGKTVNSQTSK
CCCCHHHHHHHHHHCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEECCCCCC
GIWLQCSDRERTELRGILTQFKRSQIYPDQTMRVRRIILSLLWTNDYKTAAQLSEMLAVS
CEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RNTILSDLNHVDEFLTSWNIELERKQRTGYRLHGNELQLRLMLEHIIYNSLDDYQIYKLT
HHHHHHHHHHHHHHHHHCCCEEEECCCCCCEECCCHHHHHHHHHHHHHCCCCCCHHHHHH
TRITKKERQIEIGTILEEPLKPIYEMAENHMSAFYSPSLASLLRLSDLLKFLLRLTFSVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RLTMGRAIHSYRMLQPSHDQDELSLFLVNVMEKVYTDMQLPLLEEEYAYVAGIMEKESEQ
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
IDVVDITEKMIQYVSEQERIDYKKDPKLYSNLLSHLSLRLQNGSFYLNEMNPMEDEVKRN
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEECCCEEECCCCCCHHHHHHH
HASLFQSVKESCRKYVKQHTLIAQDSFISFIVLHFLVSYENTFKRKKKVKVLYVCSTGRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCH
VARLIKNRVEKEIPAVDIVCYCSLLEVEEICQAEEVDLIISVFPVEAAVPVVVVEPLPAK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCEEEECCCCCC
RDIEEIRKQVRAMIGSDDEQTNELLENNEFTISEDSENLSQEIILKGFEAAHALLEAFPI
CCHHHHHHHHHHHHCCCCHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
KSEERWKNAFMMHVFLMVHRYYFDKQYDQYLYANNQMLDSDEEMFHSVQQILQDKDLHVH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCH
EAEVITLLQYLKKWK
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]