Click here to switch to the map view.

The map label for this gene is yhdH [H]

Identifier: 56963045

GI number: 56963045

Start: 1396470

End: 1397837

Strand: Direct

Name: yhdH [H]

Synonym: ABC1273

Alternate gene names: 56963045

Gene position: 1396470-1397837 (Clockwise)

Preceding gene: 56963043

Following gene: 56963046

Centisome position: 32.45

GC content: 45.54

Gene sequence:

>1368_bases
ATGGCAACTTCACAACAATGGTCTTCAAAATTAGGTTTTTTATATGCAACGGCTGGCAGCGCAATTGGCCTCGGCGCTAT
ATGGAAGTTTCCTTACATTGCAGGCACAAGCGGTGGAGGCGCTTTTTTTGTGCTTTTCCTCGCATTTACTTTGCTGATAG
GTGTTCCTTTACTTATCGGTGAATACGTGCTTGGTCGCCATTCAGGCCGAGACGCGATTTCAACCTATAACATGCTGGCG
CCCCGTTCGGTCTGGAGTGTGACAGGCTGGCTTGGCGTCGTCACTTGTTTTTTGATCCTGTCTTTTTACAGCGTCGTCGG
GGGCTGGTCGCTGATTTATTTAGGTTCCTCCTTATTTGGCCAGCTAGGCGGCCTTGATGTAGGCGGGTACCAAGCTAAAT
TTACGGGATTGATCGCAAATCCTTATTTGGCTGTCGGGGCACAGGCGTTGTTTTTAGGATTGACGGCTGCCGTTGTGCAA
AAAGGGGTCCAGAAAGGGATTGAACGAGCAAGCAAATGGATGATTCCCGCTTTGTTTGTCCTTTTAGTGCTATTGTCGAT
TTATTCACTCACACTTGATGGAGCTAAGGAAGGACTGGCCTTTCTGTTCAAGCCAAATTGGGAAAGCCTTTCAAGCGAAG
TAGTTTTGTTCGCCCTTGGCCAATCCTTTTTTGCTTTATCGATTGGCGTTTCGGTGATGGTGACTTTCAGTTCATATGCG
TCAAAAAAGCAAGATTTGCCTGTATCTGCTGCTACATTAGGGGTAATGAATATTTTTGTCGCAATGCTGGCAGGAATCGT
TATATTCCCCGGTGTGTTCACTTTCGGTCTAGAACCAAGCGAAGGGCCGACGCTTATTTTTGCAGCCGTGCCAGCGATTT
TTTCGCAAATGCCATTTGGCGATATCGTGGTTGTCCTCTTTTTCATGCTTTTCTTCTTCGCTGCTCTTAGCACCGCTTTT
TCACTGTTAGAAATTGTCGTCGCTGCCTTTATGAGAGGGGATGGAGACAAACGGGCAAAAGGAAGCTGGCTAATCGCTTT
GTTTGTGTTGCTGATGGGCATTCCTTCTGCATTGTCATTTGGCGTGATCGGGGATGTGCACCTATTTGGTATGCCCTTTT
TCGACTTGGTGGATTTTCTTGCATCCAACATATTGATGCCGATTGGTTCGTTGCTCATATGCATCTTTTTGCTTGTTAAA
GTAAAACGACAAACACTCGCAGCAGAATTCCAAATGGGCAGCGTCCTTGGCAAAAAAGCTTTTACATTATGGTATACGAT
TATGACCGGTATCGTTCCTGTAGCAATTGCCGTTGTCTTGATTGACCAATTTTTTGGATTTAATCTATTTGCTCTCCTAT
TTTCTTGA

Upstream 100 bases:

>100_bases
GTTAGCCAAAAGTCGGTAAGTTTTCAGAACAGGGCAGGCTTGTTTCTTAAAGCTTCCTTTGGTACGATAAAAAAATCGTG
TGTAATAAAGGAGCAACAAC

Downstream 100 bases:

>100_bases
AATATGTTATAATAGCAAAAAGCAAGAGGGGGCATCATTGTGAATAAGGACGAATTGCATGTTTATCTTGAGAAAAAGTT
GAGCGATGCAAAAGTGCAAT

Product: SNF family sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MATSQQWSSKLGFLYATAGSAIGLGAIWKFPYIAGTSGGGAFFVLFLAFTLLIGVPLLIGEYVLGRHSGRDAISTYNMLA
PRSVWSVTGWLGVVTCFLILSFYSVVGGWSLIYLGSSLFGQLGGLDVGGYQAKFTGLIANPYLAVGAQALFLGLTAAVVQ
KGVQKGIERASKWMIPALFVLLVLLSIYSLTLDGAKEGLAFLFKPNWESLSSEVVLFALGQSFFALSIGVSVMVTFSSYA
SKKQDLPVSAATLGVMNIFVAMLAGIVIFPGVFTFGLEPSEGPTLIFAAVPAIFSQMPFGDIVVVLFFMLFFFAALSTAF
SLLEIVVAAFMRGDGDKRAKGSWLIALFVLLMGIPSALSFGVIGDVHLFGMPFFDLVDFLASNILMPIGSLLICIFLLVK
VKRQTLAAEFQMGSVLGKKAFTLWYTIMTGIVPVAIAVVLIDQFFGFNLFALLFS

Sequences:

>Translated_455_residues
MATSQQWSSKLGFLYATAGSAIGLGAIWKFPYIAGTSGGGAFFVLFLAFTLLIGVPLLIGEYVLGRHSGRDAISTYNMLA
PRSVWSVTGWLGVVTCFLILSFYSVVGGWSLIYLGSSLFGQLGGLDVGGYQAKFTGLIANPYLAVGAQALFLGLTAAVVQ
KGVQKGIERASKWMIPALFVLLVLLSIYSLTLDGAKEGLAFLFKPNWESLSSEVVLFALGQSFFALSIGVSVMVTFSSYA
SKKQDLPVSAATLGVMNIFVAMLAGIVIFPGVFTFGLEPSEGPTLIFAAVPAIFSQMPFGDIVVVLFFMLFFFAALSTAF
SLLEIVVAAFMRGDGDKRAKGSWLIALFVLLMGIPSALSFGVIGDVHLFGMPFFDLVDFLASNILMPIGSLLICIFLLVK
VKRQTLAAEFQMGSVLGKKAFTLWYTIMTGIVPVAIAVVLIDQFFGFNLFALLFS
>Mature_454_residues
ATSQQWSSKLGFLYATAGSAIGLGAIWKFPYIAGTSGGGAFFVLFLAFTLLIGVPLLIGEYVLGRHSGRDAISTYNMLAP
RSVWSVTGWLGVVTCFLILSFYSVVGGWSLIYLGSSLFGQLGGLDVGGYQAKFTGLIANPYLAVGAQALFLGLTAAVVQK
GVQKGIERASKWMIPALFVLLVLLSIYSLTLDGAKEGLAFLFKPNWESLSSEVVLFALGQSFFALSIGVSVMVTFSSYAS
KKQDLPVSAATLGVMNIFVAMLAGIVIFPGVFTFGLEPSEGPTLIFAAVPAIFSQMPFGDIVVVLFFMLFFFAALSTAFS
LLEIVVAAFMRGDGDKRAKGSWLIALFVLLMGIPSALSFGVIGDVHLFGMPFFDLVDFLASNILMPIGSLLICIFLLVKV
KRQTLAAEFQMGSVLGKKAFTLWYTIMTGIVPVAIAVVLIDQFFGFNLFALLFS

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI4507043, Length=375, Percent_Identity=26.4, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI33354281, Length=293, Percent_Identity=27.9863481228669, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI58219014, Length=292, Percent_Identity=28.0821917808219, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI188528618, Length=376, Percent_Identity=25.531914893617, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI21361581, Length=433, Percent_Identity=24.7113163972286, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI194018524, Length=292, Percent_Identity=31.8493150684932, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI171184408, Length=439, Percent_Identity=24.6013667425968, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI171184406, Length=439, Percent_Identity=24.6013667425968, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI171184404, Length=439, Percent_Identity=24.6013667425968, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI51468073, Length=295, Percent_Identity=25.7627118644068, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI7657587, Length=376, Percent_Identity=24.7340425531915, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI11181770, Length=290, Percent_Identity=28.9655172413793, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI134304856, Length=418, Percent_Identity=26.3157894736842, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI4507041, Length=385, Percent_Identity=24.9350649350649, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI289191377, Length=384, Percent_Identity=24.21875, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI289191351, Length=384, Percent_Identity=24.4791666666667, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI4557046, Length=384, Percent_Identity=24.4791666666667, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI21361693, Length=111, Percent_Identity=35.1351351351351, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI12408638, Length=268, Percent_Identity=26.4925373134328, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI197276623, Length=119, Percent_Identity=31.9327731092437, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI54607094, Length=119, Percent_Identity=31.9327731092437, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI197276625, Length=118, Percent_Identity=32.2033898305085, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI6005715, Length=190, Percent_Identity=25.7894736842105, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17555248, Length=389, Percent_Identity=28.0205655526992, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25146584, Length=410, Percent_Identity=25.609756097561, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17554804, Length=464, Percent_Identity=23.4913793103448, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17542050, Length=123, Percent_Identity=34.1463414634146, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI133952791, Length=188, Percent_Identity=31.9148936170213, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI17136952, Length=433, Percent_Identity=27.2517321016166, Blast_Score=151, Evalue=9e-37,
Organism=Drosophila melanogaster, GI281364394, Length=437, Percent_Identity=27.2311212814645, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI28574704, Length=437, Percent_Identity=27.2311212814645, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI17136950, Length=437, Percent_Identity=27.2311212814645, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI28574702, Length=437, Percent_Identity=27.2311212814645, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24762620, Length=503, Percent_Identity=26.6401590457256, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24639514, Length=505, Percent_Identity=24.3564356435644, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI221329674, Length=510, Percent_Identity=24.9019607843137, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24639516, Length=296, Percent_Identity=28.7162162162162, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24661428, Length=491, Percent_Identity=23.6252545824847, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI19921936, Length=498, Percent_Identity=23.2931726907631, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI45551088, Length=496, Percent_Identity=24.7983870967742, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24652942, Length=496, Percent_Identity=24.7983870967742, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24655079, Length=292, Percent_Identity=28.7671232876712, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24582567, Length=481, Percent_Identity=24.5322245322245, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281365034, Length=495, Percent_Identity=24.8484848484848, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24639853, Length=396, Percent_Identity=25, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24654186, Length=118, Percent_Identity=33.0508474576271, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281364136, Length=228, Percent_Identity=27.6315789473684, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 48701; Mature: 48569

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSQQWSSKLGFLYATAGSAIGLGAIWKFPYIAGTSGGGAFFVLFLAFTLLIGVPLLIG
CCCCHHHHHCCCEEEEECCCCCCHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHH
EYVLGRHSGRDAISTYNMLAPRSVWSVTGWLGVVTCFLILSFYSVVGGWSLIYLGSSLFG
HHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QLGGLDVGGYQAKFTGLIANPYLAVGAQALFLGLTAAVVQKGVQKGIERASKWMIPALFV
HHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLVLLSIYSLTLDGAKEGLAFLFKPNWESLSSEVVLFALGQSFFALSIGVSVMVTFSSYA
HHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKKQDLPVSAATLGVMNIFVAMLAGIVIFPGVFTFGLEPSEGPTLIFAAVPAIFSQMPFG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHCCCCH
DIVVVLFFMLFFFAALSTAFSLLEIVVAAFMRGDGDKRAKGSWLIALFVLLMGIPSALSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHH
GVIGDVHLFGMPFFDLVDFLASNILMPIGSLLICIFLLVKVKRQTLAAEFQMGSVLGKKA
CCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTLWYTIMTGIVPVAIAVVLIDQFFGFNLFALLFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATSQQWSSKLGFLYATAGSAIGLGAIWKFPYIAGTSGGGAFFVLFLAFTLLIGVPLLIG
CCCHHHHHCCCEEEEECCCCCCHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]