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The map label for this gene is glpD [H]

Identifier: 56963029

GI number: 56963029

Start: 1374595

End: 1376253

Strand: Direct

Name: glpD [H]

Synonym: ABC1257

Alternate gene names: 56963029

Gene position: 1374595-1376253 (Clockwise)

Preceding gene: 56963028

Following gene: 56963030

Centisome position: 31.94

GC content: 46.96

Gene sequence:

>1659_bases
ATGGCGTTTTCAGCAAAGACAAGAGAAAAAGCAATTGCAAGCATGGAAGGCAAACAGTTAGATCTGTTAATTATTGGTGG
TGGCATTACTGGCGTAGGGGCCGCTTTGGATGCGGCAACACGAGGAATCGATGTCGGCTTGATTGAAATGCAAGATTTTG
CGGCGGGAACGTCAAGCCGGTCGACAAAGTTGATCCATGGTGGCCTTCGTTATTTAAAGCAATTTGAAGTTAAATTAGTT
GCTGAAGTTGGCACTGAGCGGGCGATCGTCTATGAAAATGCACCCCATGTTACAGAGCCCGTGCGAATGATGTTGCCGTT
TTACAAAGGCGGTACGTTTAATGCGTTAACAACGTCAATCGGGCTTGCTGTCTACGATCGACTTGCAGGCGTCAAGAAAG
CAGAGCGGCGCACGATGATGAAGGCGAAAGATGCATTAAAAAAAGAGCCGATTTTGGCAAAAGACGGCCTTCGCGGCGCC
GGTATGTATGTCGAATACCGCACGGACGACGCCCGCTTAACGATTGAAATTGCAAAAACAGCAGCTGAAAAAGGCGCGAA
ATTAGCGAACTATGTAAAAGCGGAAGGATTTATTTATGACAAAGGGAAAATTACGGGTGTCATTGCCCGTGATTTGCTGA
CGGGTGAAGCTGTCACGATCCAGGCAAAAAAAGTTGTCAATGCAACGGGGCCATGGGTCGACCATTTGCGTGAGCAAGAT
CGCTCAAAGACCGGAAAAACGATCCATTTAACGAAAGGCGTCCACTTGGTATTATCCAAAAAAAGATTGCCTTTAAACCA
AGCGCTTTATTTTGACACGCCTTTTGGCGATGGCCGCATGATGTTTGCGATTCCTCGCGGTGAAAAAGTGTATGTAGGCA
CAACCGATACAAATTATAAAGGCGATAAGCGGGAACCTGGTGTGACGAAGGAAGATGTCGACTATATTATGAAGGCAACA
AATGCCTTATTCCCAGGATATCAGCTCACAACTGCCGATATTGAGTCAAGCTGGTCAGGGTTGCGGCCCCTTATTCACGA
AGAAGGCAAAAGCCCTTCCGATATTTCACGTAAAGACGAAATTTTTCACTCAGACAGTGGGCTTATGACGATAGCAGGCG
GCAAATTGACTGGTTACCGAAAGATGGCCGACAATATTGTCTCGATCGTCGCCAAAGAGCTTGAACAAGAAACAGGTGCG
GTCTATAAACCGTGCCAGACAAAAAAACTGGTTTTATCAGGTGGGGAAGTAGGTGGATCGGACCAGCTCGACATGTTTAA
TGCTGCCCATATTGAAGCTGGAAAAACCCTTGGCTTAGAAGAGGCTGAAGCAGCTGAACTCGTCACACGTTACGGTTCAA
ATGTGACGCACGTGTTTGCGTTTCTAAATGATGGGGAAGCAGAGAAATATGGGCTTCCAAAAGCAGTATGGGCGTCGCTC
CGTTACGCGATGGCCTATGAAATGGCACTCACGCCTGTCGATTTCTTATTACGCCGCTCTTCCTATATGCTCTTTGATAT
TGACAAAGCCAACGCTTATAAAGACAAAATCGTGGAGGCTATGGCTTCTGTTTTGAAGTGGAGCGACAAACAGCGGGCCA
TTTACGAGGCTGAGTTGGCAGAACAATGGCGGATACACACGCTTGAGGATATCGGTTAA

Upstream 100 bases:

>100_bases
GGATCTGAGGAATTGAGGGATCACAGCATTCAATAGGCGCCAAAAGGCCTGTTTTGTTTGTTGTGGTCCCTTTTTCCGTT
CAAATATTGGAGGAATCGAG

Downstream 100 bases:

>100_bases
GCGATGTTTGGCGGCCAAACGATTTTACCAGCAATCAAGACAATGAAAGATTTCGAGGTCATTATGAACAGCAGCCATGA
ATATTTCGTTGTCTTGGATT

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MAFSAKTREKAIASMEGKQLDLLIIGGGITGVGAALDAATRGIDVGLIEMQDFAAGTSSRSTKLIHGGLRYLKQFEVKLV
AEVGTERAIVYENAPHVTEPVRMMLPFYKGGTFNALTTSIGLAVYDRLAGVKKAERRTMMKAKDALKKEPILAKDGLRGA
GMYVEYRTDDARLTIEIAKTAAEKGAKLANYVKAEGFIYDKGKITGVIARDLLTGEAVTIQAKKVVNATGPWVDHLREQD
RSKTGKTIHLTKGVHLVLSKKRLPLNQALYFDTPFGDGRMMFAIPRGEKVYVGTTDTNYKGDKREPGVTKEDVDYIMKAT
NALFPGYQLTTADIESSWSGLRPLIHEEGKSPSDISRKDEIFHSDSGLMTIAGGKLTGYRKMADNIVSIVAKELEQETGA
VYKPCQTKKLVLSGGEVGGSDQLDMFNAAHIEAGKTLGLEEAEAAELVTRYGSNVTHVFAFLNDGEAEKYGLPKAVWASL
RYAMAYEMALTPVDFLLRRSSYMLFDIDKANAYKDKIVEAMASVLKWSDKQRAIYEAELAEQWRIHTLEDIG

Sequences:

>Translated_552_residues
MAFSAKTREKAIASMEGKQLDLLIIGGGITGVGAALDAATRGIDVGLIEMQDFAAGTSSRSTKLIHGGLRYLKQFEVKLV
AEVGTERAIVYENAPHVTEPVRMMLPFYKGGTFNALTTSIGLAVYDRLAGVKKAERRTMMKAKDALKKEPILAKDGLRGA
GMYVEYRTDDARLTIEIAKTAAEKGAKLANYVKAEGFIYDKGKITGVIARDLLTGEAVTIQAKKVVNATGPWVDHLREQD
RSKTGKTIHLTKGVHLVLSKKRLPLNQALYFDTPFGDGRMMFAIPRGEKVYVGTTDTNYKGDKREPGVTKEDVDYIMKAT
NALFPGYQLTTADIESSWSGLRPLIHEEGKSPSDISRKDEIFHSDSGLMTIAGGKLTGYRKMADNIVSIVAKELEQETGA
VYKPCQTKKLVLSGGEVGGSDQLDMFNAAHIEAGKTLGLEEAEAAELVTRYGSNVTHVFAFLNDGEAEKYGLPKAVWASL
RYAMAYEMALTPVDFLLRRSSYMLFDIDKANAYKDKIVEAMASVLKWSDKQRAIYEAELAEQWRIHTLEDIG
>Mature_551_residues
AFSAKTREKAIASMEGKQLDLLIIGGGITGVGAALDAATRGIDVGLIEMQDFAAGTSSRSTKLIHGGLRYLKQFEVKLVA
EVGTERAIVYENAPHVTEPVRMMLPFYKGGTFNALTTSIGLAVYDRLAGVKKAERRTMMKAKDALKKEPILAKDGLRGAG
MYVEYRTDDARLTIEIAKTAAEKGAKLANYVKAEGFIYDKGKITGVIARDLLTGEAVTIQAKKVVNATGPWVDHLREQDR
SKTGKTIHLTKGVHLVLSKKRLPLNQALYFDTPFGDGRMMFAIPRGEKVYVGTTDTNYKGDKREPGVTKEDVDYIMKATN
ALFPGYQLTTADIESSWSGLRPLIHEEGKSPSDISRKDEIFHSDSGLMTIAGGKLTGYRKMADNIVSIVAKELEQETGAV
YKPCQTKKLVLSGGEVGGSDQLDMFNAAHIEAGKTLGLEEAEAAELVTRYGSNVTHVFAFLNDGEAEKYGLPKAVWASLR
YAMAYEMALTPVDFLLRRSSYMLFDIDKANAYKDKIVEAMASVLKWSDKQRAIYEAELAEQWRIHTLEDIG

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=550, Percent_Identity=33.4545454545455, Blast_Score=273, Evalue=4e-73,
Organism=Homo sapiens, GI285002231, Length=550, Percent_Identity=33.4545454545455, Blast_Score=273, Evalue=4e-73,
Organism=Escherichia coli, GI2367226, Length=490, Percent_Identity=32.2448979591837, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1788574, Length=391, Percent_Identity=28.3887468030691, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI115534726, Length=552, Percent_Identity=33.695652173913, Blast_Score=259, Evalue=4e-69,
Organism=Caenorhabditis elegans, GI17509253, Length=553, Percent_Identity=34.5388788426763, Blast_Score=240, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6322036, Length=583, Percent_Identity=33.4476843910806, Blast_Score=270, Evalue=3e-73,
Organism=Drosophila melanogaster, GI161077125, Length=548, Percent_Identity=34.3065693430657, Blast_Score=251, Evalue=6e-67,
Organism=Drosophila melanogaster, GI24653942, Length=548, Percent_Identity=34.3065693430657, Blast_Score=251, Evalue=6e-67,
Organism=Drosophila melanogaster, GI24653944, Length=548, Percent_Identity=34.3065693430657, Blast_Score=251, Evalue=6e-67,
Organism=Drosophila melanogaster, GI20130025, Length=548, Percent_Identity=34.3065693430657, Blast_Score=251, Evalue=6e-67,
Organism=Drosophila melanogaster, GI24586295, Length=542, Percent_Identity=29.520295202952, Blast_Score=182, Evalue=5e-46,
Organism=Drosophila melanogaster, GI19921278, Length=546, Percent_Identity=26.5567765567766, Blast_Score=166, Evalue=4e-41,
Organism=Drosophila melanogaster, GI45550977, Length=396, Percent_Identity=24.2424242424242, Blast_Score=106, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 60595; Mature: 60464

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFSAKTREKAIASMEGKQLDLLIIGGGITGVGAALDAATRGIDVGLIEMQDFAAGTSSR
CCCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEHHHCCCCCCC
STKLIHGGLRYLKQFEVKLVAEVGTERAIVYENAPHVTEPVRMMLPFYKGGTFNALTTSI
CHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCHHHHHHH
GLAVYDRLAGVKKAERRTMMKAKDALKKEPILAKDGLRGAGMYVEYRTDDARLTIEIAKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEECCCCEEEEEEEHH
AAEKGAKLANYVKAEGFIYDKGKITGVIARDLLTGEAVTIQAKKVVNATGPWVDHLREQD
HHHCCHHHHHHHHHCCEEEECCCEEEEEHHHHHCCCEEEEEEHHHHCCCCHHHHHHHHHH
RSKTGKTIHLTKGVHLVLSKKRLPLNQALYFDTPFGDGRMMFAIPRGEKVYVGTTDTNYK
HHCCCCEEEEECCEEEEEECCCCCCCCEEEEECCCCCCEEEEEECCCCEEEEECCCCCCC
GDKREPGVTKEDVDYIMKATNALFPGYQLTTADIESSWSGLRPLIHEEGKSPSDISRKDE
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCHHHCHHHCCHHHHHCCCCCCCCCHHHH
IFHSDSGLMTIAGGKLTGYRKMADNIVSIVAKELEQETGAVYKPCQTKKLVLSGGEVGGS
HEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEECCCCCCC
DQLDMFNAAHIEAGKTLGLEEAEAAELVTRYGSNVTHVFAFLNDGEAEKYGLPKAVWASL
CCCCCCCHHEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCHHHHCCCHHHHHHH
RYAMAYEMALTPVDFLLRRSSYMLFDIDKANAYKDKIVEAMASVLKWSDKQRAIYEAELA
HHHHHHHHHCCHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
EQWRIHTLEDIG
HHHCCCCHHCCC
>Mature Secondary Structure 
AFSAKTREKAIASMEGKQLDLLIIGGGITGVGAALDAATRGIDVGLIEMQDFAAGTSSR
CCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEHHHCCCCCCC
STKLIHGGLRYLKQFEVKLVAEVGTERAIVYENAPHVTEPVRMMLPFYKGGTFNALTTSI
CHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCHHHHHHH
GLAVYDRLAGVKKAERRTMMKAKDALKKEPILAKDGLRGAGMYVEYRTDDARLTIEIAKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEECCCCEEEEEEEHH
AAEKGAKLANYVKAEGFIYDKGKITGVIARDLLTGEAVTIQAKKVVNATGPWVDHLREQD
HHHCCHHHHHHHHHCCEEEECCCEEEEEHHHHHCCCEEEEEEHHHHCCCCHHHHHHHHHH
RSKTGKTIHLTKGVHLVLSKKRLPLNQALYFDTPFGDGRMMFAIPRGEKVYVGTTDTNYK
HHCCCCEEEEECCEEEEEECCCCCCCCEEEEECCCCCCEEEEEECCCCEEEEECCCCCCC
GDKREPGVTKEDVDYIMKATNALFPGYQLTTADIESSWSGLRPLIHEEGKSPSDISRKDE
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCHHHCHHHCCHHHHHCCCCCCCCCHHHH
IFHSDSGLMTIAGGKLTGYRKMADNIVSIVAKELEQETGAVYKPCQTKKLVLSGGEVGGS
HEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEECCCCCCC
DQLDMFNAAHIEAGKTLGLEEAEAAELVTRYGSNVTHVFAFLNDGEAEKYGLPKAVWASL
CCCCCCCHHEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCHHHHCCCHHHHHHH
RYAMAYEMALTPVDFLLRRSSYMLFDIDKANAYKDKIVEAMASVLKWSDKQRAIYEAELA
HHHHHHHHHCCHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
EQWRIHTLEDIG
HHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2127799; 9579061; 9384377; 1809833 [H]