Click here to switch to the map view.

The map label for this gene is hbpA [H]

Identifier: 56963012

GI number: 56963012

Start: 1352876

End: 1354525

Strand: Direct

Name: hbpA [H]

Synonym: ABC1240

Alternate gene names: 56963012

Gene position: 1352876-1354525 (Clockwise)

Preceding gene: 56963011

Following gene: 56963013

Centisome position: 31.43

GC content: 46.24

Gene sequence:

>1650_bases
ATGAAAAAAGCAAAAATGCCTCTTTTCTCTGCGGCGTTGTTAGCCGTCTTTGTCCTTGGTGCATGCGGAGGCGATGAAAC
AAGCACAGATGGAAATGGCGAACAAAACAACAACGGCGGTGAAGAAAGCAGCAGCGGAGGCACGCTTATTTTTGCCCGTG
GCGGCGACTCGCAAAGCCTTGATTATGCTTCGGTTACAGACGGGGAATCGTCTCGTGTGACCAAACAAATTTATGAAACG
TTGATTGAATTTGCCGATGATTCATTTGAATTGGAGCCAGGGCTTGCTAAAGATTGGGATGTTGATGACGAAGGGCTCCG
TTATGTGTTTTATTTACAAGAAGGTGTTACATTTCACGATGGCACGCCATTTAATGCCGATGCAGTGAAAACAAATTTTG
AGCGCTGGGCAGACCCGGATCATGAATATGCCTTTACCGATGAAGGGTACAGTTACAGTGTATATGGCACCCAGTTCGGC
GGTTTTAAAGGCGATGATGGCCATGTGATTGAGGAAATTAATGTGATTGATGATTATGAAGTCGAGTTTGTCCTGTCCAA
ACCCCTTGGTTCATTTTTACAAAACATGGGGATGAGTTATTTTGCGATAACATCTCCAGCAGCCCTTGAAGAATATGGCG
CTGATATTGATGAAAATCCAGTTGGTACAGGGCCGTTCAAATTTGTCAGTTGGACAAAAGACGCAAGCATTGTCCTCGAA
AAAAATGAAGATTACTGGCAGGAGGGCTTGCCAAAACTAGATGGCGTCACTTTCCAAGTGATCCCTGATAACTCAGCGCG
CTTAACGGCGCTCCAATCTGGTGAAATTGATTTAATGGATGGCCTTGCCCCTGATGATGCCGCCATGATTGAAGGGCAAG
CAGGATTAACAACGTTTGAGCGGACGCCAAACAACGTTGGCTATCTAGGCTTCAACATAGAAAAGGAGCCATTTAATGAT
GTCCGCGTGCGCCAGGCTATTAACCACGCCATTGATAAAAACGAAATTATTAATAATATTTACGGTGGATTGGCGGAGCC
GGCTGCCAATGCTGTACCAAAAGACTACCTTGGGCACAATGATGACGTTGTCGCCTATGAATACGATATGGATAAAGCAA
AAGAATTGCTCGAAGAAGCTGGTTATGGCGATGGATTTGAATTTGACTTGTGGACGATGCCGGTGAGCCGCCCTTACATG
CCTGATCCTGAACAAGCAGCGGTGGTGATCCAAGATGCCCTGAGTGAATTAAACATTACTGCTAATATCGTCACAAAAGA
ATGGGCAACGTACTTGGAGGAAATCGAGCTTGGCTATCAAGATATGTTCATGCTTGGCTGGTCTGGCGTCAATGGCGACC
CTGATTACTTCCTTGGCAGCTTATTGTCTACAGACGGCATTCCTGGCAGCAACCAAATGTTTTTTAGCAACGAAGAAGTC
GATGCCTTGTTAGCAGAAGCAAAGACGACGATTGATCCAGACGAACGGGCGGCATTGTACGAAGAAGCGCAATTGATCAT
TCATGAGGAAGCGCCAATGGTGCCTCTTGTCCATGCCATTCCTGCGCTCGCTGGCGTCGACACCATTTCCGGCTATGTTC
CGCATCCGTCAACAAGCGAGAGCTTGAAACATGTAGAAATTTCAAACTAG

Upstream 100 bases:

>100_bases
ACATATGCAAAATAAAAACGCCTGTTTGGCGTGACGTCGGCAATGGGCAGTTTACAGCGTGCCATTTGTATAATGAAACC
ACCGAAAAGGAGATGATCAA

Downstream 100 bases:

>100_bases
CCTACTGCAGGCAGCAGACAATTTCCTGCTGCCTGTCTTTATTCAATAAAATGAGGTGAAGCCGATGTTGGCGTACGCGA
TTCGCCGGGTTCTTTTGCTT

Product: oligopeptide ABC transporter substrate-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MKKAKMPLFSAALLAVFVLGACGGDETSTDGNGEQNNNGGEESSSGGTLIFARGGDSQSLDYASVTDGESSRVTKQIYET
LIEFADDSFELEPGLAKDWDVDDEGLRYVFYLQEGVTFHDGTPFNADAVKTNFERWADPDHEYAFTDEGYSYSVYGTQFG
GFKGDDGHVIEEINVIDDYEVEFVLSKPLGSFLQNMGMSYFAITSPAALEEYGADIDENPVGTGPFKFVSWTKDASIVLE
KNEDYWQEGLPKLDGVTFQVIPDNSARLTALQSGEIDLMDGLAPDDAAMIEGQAGLTTFERTPNNVGYLGFNIEKEPFND
VRVRQAINHAIDKNEIINNIYGGLAEPAANAVPKDYLGHNDDVVAYEYDMDKAKELLEEAGYGDGFEFDLWTMPVSRPYM
PDPEQAAVVIQDALSELNITANIVTKEWATYLEEIELGYQDMFMLGWSGVNGDPDYFLGSLLSTDGIPGSNQMFFSNEEV
DALLAEAKTTIDPDERAALYEEAQLIIHEEAPMVPLVHAIPALAGVDTISGYVPHPSTSESLKHVEISN

Sequences:

>Translated_549_residues
MKKAKMPLFSAALLAVFVLGACGGDETSTDGNGEQNNNGGEESSSGGTLIFARGGDSQSLDYASVTDGESSRVTKQIYET
LIEFADDSFELEPGLAKDWDVDDEGLRYVFYLQEGVTFHDGTPFNADAVKTNFERWADPDHEYAFTDEGYSYSVYGTQFG
GFKGDDGHVIEEINVIDDYEVEFVLSKPLGSFLQNMGMSYFAITSPAALEEYGADIDENPVGTGPFKFVSWTKDASIVLE
KNEDYWQEGLPKLDGVTFQVIPDNSARLTALQSGEIDLMDGLAPDDAAMIEGQAGLTTFERTPNNVGYLGFNIEKEPFND
VRVRQAINHAIDKNEIINNIYGGLAEPAANAVPKDYLGHNDDVVAYEYDMDKAKELLEEAGYGDGFEFDLWTMPVSRPYM
PDPEQAAVVIQDALSELNITANIVTKEWATYLEEIELGYQDMFMLGWSGVNGDPDYFLGSLLSTDGIPGSNQMFFSNEEV
DALLAEAKTTIDPDERAALYEEAQLIIHEEAPMVPLVHAIPALAGVDTISGYVPHPSTSESLKHVEISN
>Mature_549_residues
MKKAKMPLFSAALLAVFVLGACGGDETSTDGNGEQNNNGGEESSSGGTLIFARGGDSQSLDYASVTDGESSRVTKQIYET
LIEFADDSFELEPGLAKDWDVDDEGLRYVFYLQEGVTFHDGTPFNADAVKTNFERWADPDHEYAFTDEGYSYSVYGTQFG
GFKGDDGHVIEEINVIDDYEVEFVLSKPLGSFLQNMGMSYFAITSPAALEEYGADIDENPVGTGPFKFVSWTKDASIVLE
KNEDYWQEGLPKLDGVTFQVIPDNSARLTALQSGEIDLMDGLAPDDAAMIEGQAGLTTFERTPNNVGYLGFNIEKEPFND
VRVRQAINHAIDKNEIINNIYGGLAEPAANAVPKDYLGHNDDVVAYEYDMDKAKELLEEAGYGDGFEFDLWTMPVSRPYM
PDPEQAAVVIQDALSELNITANIVTKEWATYLEEIELGYQDMFMLGWSGVNGDPDYFLGSLLSTDGIPGSNQMFFSNEEV
DALLAEAKTTIDPDERAALYEEAQLIIHEEAPMVPLVHAIPALAGVDTISGYVPHPSTSESLKHVEISN

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=519, Percent_Identity=34.2967244701349, Blast_Score=311, Evalue=6e-86,
Organism=Escherichia coli, GI1787052, Length=506, Percent_Identity=31.4229249011858, Blast_Score=257, Evalue=2e-69,
Organism=Escherichia coli, GI1787551, Length=477, Percent_Identity=27.8825995807128, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1787762, Length=505, Percent_Identity=28.3168316831683, Blast_Score=185, Evalue=8e-48,
Organism=Escherichia coli, GI1787495, Length=510, Percent_Identity=25.6862745098039, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1789397, Length=479, Percent_Identity=25.8872651356994, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1789887, Length=477, Percent_Identity=25.9958071278826, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87081878, Length=475, Percent_Identity=25.4736842105263, Blast_Score=119, Evalue=6e-28,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60186; Mature: 60186

Theoretical pI: Translated: 3.81; Mature: 3.81

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAKMPLFSAALLAVFVLGACGGDETSTDGNGEQNNNGGEESSSGGTLIFARGGDSQSL
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
DYASVTDGESSRVTKQIYETLIEFADDSFELEPGLAKDWDVDDEGLRYVFYLQEGVTFHD
CEEECCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEEEEEEECCCEECC
GTPFNADAVKTNFERWADPDHEYAFTDEGYSYSVYGTQFGGFKGDDGHVIEEINVIDDYE
CCCCCHHHHHCCHHHHCCCCCCEEECCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCE
VEFVLSKPLGSFLQNMGMSYFAITSPAALEEYGADIDENPVGTGPFKFVSWTKDASIVLE
EEEEECCHHHHHHHHCCCEEEEECCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEE
KNEDYWQEGLPKLDGVTFQVIPDNSARLTALQSGEIDLMDGLAPDDAAMIEGQAGLTTFE
CCCHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCEEEECCCCCCCHHEEECCCCCEECC
RTPNNVGYLGFNIEKEPFNDVRVRQAINHAIDKNEIINNIYGGLAEPAANAVPKDYLGHN
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHCCCHHHCCCC
DDVVAYEYDMDKAKELLEEAGYGDGFEFDLWTMPVSRPYMPDPEQAAVVIQDALSELNIT
CCEEEEECCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCEE
ANIVTKEWATYLEEIELGYQDMFMLGWSGVNGDPDYFLGSLLSTDGIPGSNQMFFSNEEV
EEEHHHHHHHHHHHHHCCHHHEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEECCCHH
DALLAEAKTTIDPDERAALYEEAQLIIHEEAPMVPLVHAIPALAGVDTISGYVPHPSTSE
HHHHHHHHCCCCCHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
SLKHVEISN
CCCEEEECC
>Mature Secondary Structure
MKKAKMPLFSAALLAVFVLGACGGDETSTDGNGEQNNNGGEESSSGGTLIFARGGDSQSL
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
DYASVTDGESSRVTKQIYETLIEFADDSFELEPGLAKDWDVDDEGLRYVFYLQEGVTFHD
CEEECCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEEEEEEECCCEECC
GTPFNADAVKTNFERWADPDHEYAFTDEGYSYSVYGTQFGGFKGDDGHVIEEINVIDDYE
CCCCCHHHHHCCHHHHCCCCCCEEECCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCE
VEFVLSKPLGSFLQNMGMSYFAITSPAALEEYGADIDENPVGTGPFKFVSWTKDASIVLE
EEEEECCHHHHHHHHCCCEEEEECCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEE
KNEDYWQEGLPKLDGVTFQVIPDNSARLTALQSGEIDLMDGLAPDDAAMIEGQAGLTTFE
CCCHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCEEEECCCCCCCHHEEECCCCCEECC
RTPNNVGYLGFNIEKEPFNDVRVRQAINHAIDKNEIINNIYGGLAEPAANAVPKDYLGHN
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHCCCHHHCCCC
DDVVAYEYDMDKAKELLEEAGYGDGFEFDLWTMPVSRPYMPDPEQAAVVIQDALSELNIT
CCEEEEECCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCEE
ANIVTKEWATYLEEIELGYQDMFMLGWSGVNGDPDYFLGSLLSTDGIPGSNQMFFSNEEV
EEEHHHHHHHHHHHHHCCHHHEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEECCCHH
DALLAEAKTTIDPDERAALYEEAQLIIHEEAPMVPLVHAIPALAGVDTISGYVPHPSTSE
HHHHHHHHCCCCCHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
SLKHVEISN
CCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]