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The map label for this gene is mnmG [H]

Identifier: 55981941

GI number: 55981941

Start: 1846329

End: 1848122

Strand: Reverse

Name: mnmG [H]

Synonym: TTHA1972

Alternate gene names: 55981941

Gene position: 1848122-1846329 (Counterclockwise)

Preceding gene: NA

Following gene: 55981940

Centisome position: 99.91

GC content: 72.24

Gene sequence:

>1794_bases
ATGGCGGGCTACGACGTGGTGGTGGTGGGAGGGGGCCACGCGGGCCTCGAGGCGGCCTGGGCGGCGGCCGCCCTGGGGGT
CCGGGTGGCCCTGGTGACGGTGAACCCCGACCGGATCGGCATGATGCCCTGTAACCCCGCCGTGGGGGGGCCGGGGAAAA
GCCAGCTCGTGGCGGAGGTGGTGGCCCTGGGCGGGCTCATGGGCCGGGCGGCGGACGCCGCCGCCATCCACACCCGGGTC
CTGAACCGCTCCAAGGGCCCTGCGGTGCAAAGCCTTAGGGTCCAGGTGGACCGGGACCTCTACGCCCTCAAGGCCCAGGA
GATCCTCGCGGAAAGGCCCGTGGAGGTGCTGCGGGGCGAGGTGGCGGCCCTCTGGGTAGAGGGGGGGAGGCTTCTCGGCG
TCCGCACCGTGGACGGGCGGACCCTCCCCGCCAAGGCGGTGGTGGTGGCGGGGGGGACCTTCCTTTCCGGGGTGGTCTGG
TACGGAAGGAAGAGCCGTCCCGCCGGGCGCCAGGGGGAGCCCCCGGCCCGTTTCCTCTCCCAAAGCCTCAAGGCGGTGGG
CCACACCCTGAGGCGGTTCAAGACGGGGACCCCGCCCAGGATCCGCGCGGACAGCGTGGACTTCGGGCGCCTCGAGGTGG
TCCCGCCCGAGGTGCCGCCCGGGAGTTTCACGGGAAACCCTGGGCCCCACGCCGCCAGGCTCCCCACCTGGCAGACCCGC
ACCACGGCGCGGACCCACCGCCTCATCCGCGAGAACCTCCACCTCTCCCCCCTCTACGCCGGGGACATCCAGGGCATCGG
CCCCCGGTACTGCCCCTCCATTGAGGACAAGGTGGTGCGCTTCGCCGACAAGGAGAGCCACCTCCTCTTCGTGGAGCCGG
ACGGGCTCTCCACCACCGAGGTCTACCTCCAGGGCTTCTCCTCAAGCCTCCCTCCCGAGCTCCAGGAGGAGATGGTGCGC
TCCCTCCCCGGGTTTGAGCGGGCGGTGATCCAGCGCTACGCCTACGCCGTGGAGTACGACAGCCTGGACCCCACGGAGCT
CACCCGGGGCCTCCAGTCCCGCCTCCTGCCTGGGCTTTTCAGCGCCGGGCAGGTGAACGGCACCTCGGGCTACGAGGAGG
CGGCGGCCCAGGGGCTTCTGGCCGGGCTCAACGCCGCCCGGTTCGCCCTGGGCCTTCCCGAGGTCCACCTCCCCCGGGAA
AGCGGCTACATCGGGGTCCTGGTGGACGACCTCGTGGGCCGGGGCACGGACGAGCCCTACCGGATGATGACCTCCCGGGT
GGAGCTCCGCCTCCTCTGCCGGGCGGACAACGCCGACGAGCGCCTCACCCCTTTGGCCGTGGCCTGGGGTCTGAGGCCCA
AAGAGGATCTGGAGCGGGTGGAGGCCAAGTACCGCAGGGTGGCGGCGGAGCTTAGGCGCCTTCAGGCCCTTCGGGTGGAA
GGGGTCTCCGGTCTCCAGTGGCTTAGGCGGCCGGAGAACACCTACCGGGCCCTGGCGGAGCGCTTCCCCCCGTCCGAGCC
TCTCTCCCCCGAGGAGGCCTACCAGGTGGAGGTGCGGGCCAAGTACGCGGGCTACATTGAGCGGCAGGAGCGCCTGCGGG
AGAAGATGAAGGACCTCGAGGCCTTCCGCATCCCCGAGGGGATGGACTTCCCCAAGGTGCCGGGGCTTTCCCGGGAGGCG
GCGGAGAAGCTCTCCCGCCACCGGCCCAAAAGCCTCGCCGAGGCGGCCCGGATCCCCGGGGTGCGGGACTCGGACCTCAC
GGCCCTGGCCGTCCACCTGCGGCGGGGCGCCTGA

Upstream 100 bases:

>100_bases
TGCTCCAGAACGTGTTGCCAGACGGCCTCGTGCGACAACCTTCCCCCTCCGTCGTCCCGGTCCCCCATTTTAACCCCGGG
ACCCGCTAGAGTGAGATGGG

Downstream 100 bases:

>100_bases
TGTTTCACGGGAAACACCCGGGGGGCCTGAGCGAAAGGGGCCGGGCCCTGCTCTTGGAGGGGGGAAAGGCCTTGGGCCTG
GACCTAAAGCCCCACCTGGA

Product: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A [H]

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MAGYDVVVVGGGHAGLEAAWAAAALGVRVALVTVNPDRIGMMPCNPAVGGPGKSQLVAEVVALGGLMGRAADAAAIHTRV
LNRSKGPAVQSLRVQVDRDLYALKAQEILAERPVEVLRGEVAALWVEGGRLLGVRTVDGRTLPAKAVVVAGGTFLSGVVW
YGRKSRPAGRQGEPPARFLSQSLKAVGHTLRRFKTGTPPRIRADSVDFGRLEVVPPEVPPGSFTGNPGPHAARLPTWQTR
TTARTHRLIRENLHLSPLYAGDIQGIGPRYCPSIEDKVVRFADKESHLLFVEPDGLSTTEVYLQGFSSSLPPELQEEMVR
SLPGFERAVIQRYAYAVEYDSLDPTELTRGLQSRLLPGLFSAGQVNGTSGYEEAAAQGLLAGLNAARFALGLPEVHLPRE
SGYIGVLVDDLVGRGTDEPYRMMTSRVELRLLCRADNADERLTPLAVAWGLRPKEDLERVEAKYRRVAAELRRLQALRVE
GVSGLQWLRRPENTYRALAERFPPSEPLSPEEAYQVEVRAKYAGYIERQERLREKMKDLEAFRIPEGMDFPKVPGLSREA
AEKLSRHRPKSLAEAARIPGVRDSDLTALAVHLRRGA

Sequences:

>Translated_597_residues
MAGYDVVVVGGGHAGLEAAWAAAALGVRVALVTVNPDRIGMMPCNPAVGGPGKSQLVAEVVALGGLMGRAADAAAIHTRV
LNRSKGPAVQSLRVQVDRDLYALKAQEILAERPVEVLRGEVAALWVEGGRLLGVRTVDGRTLPAKAVVVAGGTFLSGVVW
YGRKSRPAGRQGEPPARFLSQSLKAVGHTLRRFKTGTPPRIRADSVDFGRLEVVPPEVPPGSFTGNPGPHAARLPTWQTR
TTARTHRLIRENLHLSPLYAGDIQGIGPRYCPSIEDKVVRFADKESHLLFVEPDGLSTTEVYLQGFSSSLPPELQEEMVR
SLPGFERAVIQRYAYAVEYDSLDPTELTRGLQSRLLPGLFSAGQVNGTSGYEEAAAQGLLAGLNAARFALGLPEVHLPRE
SGYIGVLVDDLVGRGTDEPYRMMTSRVELRLLCRADNADERLTPLAVAWGLRPKEDLERVEAKYRRVAAELRRLQALRVE
GVSGLQWLRRPENTYRALAERFPPSEPLSPEEAYQVEVRAKYAGYIERQERLREKMKDLEAFRIPEGMDFPKVPGLSREA
AEKLSRHRPKSLAEAARIPGVRDSDLTALAVHLRRGA
>Mature_596_residues
AGYDVVVVGGGHAGLEAAWAAAALGVRVALVTVNPDRIGMMPCNPAVGGPGKSQLVAEVVALGGLMGRAADAAAIHTRVL
NRSKGPAVQSLRVQVDRDLYALKAQEILAERPVEVLRGEVAALWVEGGRLLGVRTVDGRTLPAKAVVVAGGTFLSGVVWY
GRKSRPAGRQGEPPARFLSQSLKAVGHTLRRFKTGTPPRIRADSVDFGRLEVVPPEVPPGSFTGNPGPHAARLPTWQTRT
TARTHRLIRENLHLSPLYAGDIQGIGPRYCPSIEDKVVRFADKESHLLFVEPDGLSTTEVYLQGFSSSLPPELQEEMVRS
LPGFERAVIQRYAYAVEYDSLDPTELTRGLQSRLLPGLFSAGQVNGTSGYEEAAAQGLLAGLNAARFALGLPEVHLPRES
GYIGVLVDDLVGRGTDEPYRMMTSRVELRLLCRADNADERLTPLAVAWGLRPKEDLERVEAKYRRVAAELRRLQALRVEG
VSGLQWLRRPENTYRALAERFPPSEPLSPEEAYQVEVRAKYAGYIERQERLREKMKDLEAFRIPEGMDFPKVPGLSREAA
EKLSRHRPKSLAEAARIPGVRDSDLTALAVHLRRGA

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 [H]

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family [H]

Homologues:

Organism=Homo sapiens, GI74024895, Length=620, Percent_Identity=40.4838709677419, Blast_Score=389, Evalue=1e-108,
Organism=Homo sapiens, GI19882217, Length=645, Percent_Identity=39.3798449612403, Blast_Score=376, Evalue=1e-104,
Organism=Homo sapiens, GI183227703, Length=660, Percent_Identity=38.030303030303, Blast_Score=370, Evalue=1e-102,
Organism=Escherichia coli, GI2367273, Length=615, Percent_Identity=46.6666666666667, Blast_Score=494, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI17534255, Length=618, Percent_Identity=39.4822006472492, Blast_Score=418, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6321202, Length=623, Percent_Identity=38.0417335473515, Blast_Score=385, Evalue=1e-108,
Organism=Drosophila melanogaster, GI24658174, Length=630, Percent_Identity=39.2063492063492, Blast_Score=383, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595 [H]

Pfam domain/function: PF01134 GIDA [H]

EC number: NA

Molecular weight: Translated: 65203; Mature: 65071

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS01280 GIDA_1 ; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGYDVVVVGGGHAGLEAAWAAAALGVRVALVTVNPDRIGMMPCNPAVGGPGKSQLVAEV
CCCCEEEEECCCCCCHHHHHHHHHHCEEEEEEEECCCCEECCCCCCCCCCCCHHHHHHHH
VALGGLMGRAADAAAIHTRVLNRSKGPAVQSLRVQVDRDLYALKAQEILAERPVEVLRGE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEECCCHHHHHHHHHHHHHCCHHHHCCC
VAALWVEGGRLLGVRTVDGRTLPAKAVVVAGGTFLSGVVWYGRKSRPAGRQGEPPARFLS
EEEEEECCCEEEEEEECCCCCCCCCEEEEECCHHHHHHHHCCCCCCCCCCCCCCHHHHHH
QSLKAVGHTLRRFKTGTPPRIRADSVDFGRLEVVPPEVPPGSFTGNPGPHAARLPTWQTR
HHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCH
TTARTHRLIRENLHLSPLYAGDIQGIGPRYCPSIEDKVVRFADKESHLLFVEPDGLSTTE
HHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCHHH
VYLQGFSSSLPPELQEEMVRSLPGFERAVIQRYAYAVEYDSLDPTELTRGLQSRLLPGLF
HHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHH
SAGQVNGTSGYEEAAAQGLLAGLNAARFALGLPEVHLPRESGYIGVLVDDLVGRGTDEPY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEEEHHHHHCCCCCCHH
RMMTSRVELRLLCRADNADERLTPLAVAWGLRPKEDLERVEAKYRRVAAELRRLQALRVE
HHHHHHHHEEEEEECCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVSGLQWLRRPENTYRALAERFPPSEPLSPEEAYQVEVRAKYAGYIERQERLREKMKDLE
CCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHEEEEEEHHHHHHHHHHHHHHHHHHHHH
AFRIPEGMDFPKVPGLSREAAEKLSRHRPKSLAEAARIPGVRDSDLTALAVHLRRGA
HHCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
AGYDVVVVGGGHAGLEAAWAAAALGVRVALVTVNPDRIGMMPCNPAVGGPGKSQLVAEV
CCCEEEEECCCCCCHHHHHHHHHHCEEEEEEEECCCCEECCCCCCCCCCCCHHHHHHHH
VALGGLMGRAADAAAIHTRVLNRSKGPAVQSLRVQVDRDLYALKAQEILAERPVEVLRGE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEECCCHHHHHHHHHHHHHCCHHHHCCC
VAALWVEGGRLLGVRTVDGRTLPAKAVVVAGGTFLSGVVWYGRKSRPAGRQGEPPARFLS
EEEEEECCCEEEEEEECCCCCCCCCEEEEECCHHHHHHHHCCCCCCCCCCCCCCHHHHHH
QSLKAVGHTLRRFKTGTPPRIRADSVDFGRLEVVPPEVPPGSFTGNPGPHAARLPTWQTR
HHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCH
TTARTHRLIRENLHLSPLYAGDIQGIGPRYCPSIEDKVVRFADKESHLLFVEPDGLSTTE
HHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCHHH
VYLQGFSSSLPPELQEEMVRSLPGFERAVIQRYAYAVEYDSLDPTELTRGLQSRLLPGLF
HHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHH
SAGQVNGTSGYEEAAAQGLLAGLNAARFALGLPEVHLPRESGYIGVLVDDLVGRGTDEPY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEEEHHHHHCCCCCCHH
RMMTSRVELRLLCRADNADERLTPLAVAWGLRPKEDLERVEAKYRRVAAELRRLQALRVE
HHHHHHHHEEEEEECCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVSGLQWLRRPENTYRALAERFPPSEPLSPEEAYQVEVRAKYAGYIERQERLREKMKDLE
CCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHEEEEEEHHHHHHHHHHHHHHHHHHHHH
AFRIPEGMDFPKVPGLSREAAEKLSRHRPKSLAEAARIPGVRDSDLTALAVHLRRGA
HHCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA