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The map label for this gene is gufA [H]

Identifier: 55981910

GI number: 55981910

Start: 1820901

End: 1821695

Strand: Direct

Name: gufA [H]

Synonym: TTHA1941

Alternate gene names: 55981910

Gene position: 1820901-1821695 (Clockwise)

Preceding gene: 55981906

Following gene: 55981913

Centisome position: 98.44

GC content: 70.82

Gene sequence:

>795_bases
ATGGAGCCCTTTCTCCTCTACGCCCTGCTGGGCGGCCTCTTCACCTGGGGCCTCACGGCGGTGGGGGCGGCGAGCGTCTT
CTTCGCCAGGGAGCCGAGCCGTAAGCTTCTGGACGCCATGCTGGGCTTCGCCGCCGGGGTGATGCTTGCGGCGAGCGTCT
TCTCCCTCCTCGTCCCCGGGATGGAGATGGCGGAGGCCCAGGGGAAAAACCCCATTTTCCCGGCGGTGGTGGGGTTTCTC
CTGGGCGGGGGGCTTATCCGGCTTCTGGACCGCTACCTGCCCCACGTCCACCTGGGCCCCAAGGACGCCCCCGAGGGGCT
CAAGACCCTCTGGCGCCGCACCACCCTCCTGATCCTCGCCATCGCCCTGCACAACTTCCCCGAGGGCCTGGCCGTGGGGG
TGGCTTTTGGGGCTGCGGGGCTGGACCCCACGGGCGCCGCCACCCTGGGCGGGGCCATCGCCCTCGCCTTGGGCATCGGC
CTCCAGAACCTCCCCGAGGGGCTCGCCATCGCCTGGCCCTTGCGGCGGGTGGGGATCGGGGCGGGCCTCGCCTGGTTCTA
CGGGCAACTCTCCGCCATCGTGGAGCCCCTGGGCGCGGTGCTCGGGGCCCTCCTCGTGGCCCAGATGATGGCCCTCCTTC
CCTACCTCATGGCCATGGCGGCGGGGGCCATGGTCTTCGTGGTGGTGGAGGAGGTGATCCCGGAAAGCCAGGCGGAGGGA
AACGGGGACACCGCCACCTTCGGGGTCATGACGGGCTTCGCCCTGATGATGGCCCTGGACGTGGCCCTGGGCTGA

Upstream 100 bases:

>100_bases
TACTCTTCCTCTAGGCGGTCAAGCTTGTCCAGCATACCTGTTTCCAGGATAGCGCACCCGGCCCTTGACCCCGGTTTTAG
GTTAGCCTAAACTCGGGGGC

Downstream 100 bases:

>100_bases
GCGCCGGGGCGAAGCCCTTAAAGAAGGGCCTGAAGGTCCGCCACCACCCTGTCCGTGGCCTCCGCCTTGTCCGGGCTATA
GAGGAGGACGAGCCTCCCCT

Product: zinc transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MEPFLLYALLGGLFTWGLTAVGAASVFFAREPSRKLLDAMLGFAAGVMLAASVFSLLVPGMEMAEAQGKNPIFPAVVGFL
LGGGLIRLLDRYLPHVHLGPKDAPEGLKTLWRRTTLLILAIALHNFPEGLAVGVAFGAAGLDPTGAATLGGAIALALGIG
LQNLPEGLAIAWPLRRVGIGAGLAWFYGQLSAIVEPLGAVLGALLVAQMMALLPYLMAMAAGAMVFVVVEEVIPESQAEG
NGDTATFGVMTGFALMMALDVALG

Sequences:

>Translated_264_residues
MEPFLLYALLGGLFTWGLTAVGAASVFFAREPSRKLLDAMLGFAAGVMLAASVFSLLVPGMEMAEAQGKNPIFPAVVGFL
LGGGLIRLLDRYLPHVHLGPKDAPEGLKTLWRRTTLLILAIALHNFPEGLAVGVAFGAAGLDPTGAATLGGAIALALGIG
LQNLPEGLAIAWPLRRVGIGAGLAWFYGQLSAIVEPLGAVLGALLVAQMMALLPYLMAMAAGAMVFVVVEEVIPESQAEG
NGDTATFGVMTGFALMMALDVALG
>Mature_264_residues
MEPFLLYALLGGLFTWGLTAVGAASVFFAREPSRKLLDAMLGFAAGVMLAASVFSLLVPGMEMAEAQGKNPIFPAVVGFL
LGGGLIRLLDRYLPHVHLGPKDAPEGLKTLWRRTTLLILAIALHNFPEGLAVGVAFGAAGLDPTGAATLGGAIALALGIG
LQNLPEGLAIAWPLRRVGIGAGLAWFYGQLSAIVEPLGAVLGALLVAQMMALLPYLMAMAAGAMVFVVVEEVIPESQAEG
NGDTATFGVMTGFALMMALDVALG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577422, Length=154, Percent_Identity=55.1948051948052, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI229577418, Length=154, Percent_Identity=55.1948051948052, Blast_Score=160, Evalue=1e-39,
Organism=Escherichia coli, GI1789419, Length=252, Percent_Identity=32.5396825396825, Blast_Score=94, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17507805, Length=316, Percent_Identity=43.3544303797468, Blast_Score=221, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24652846, Length=163, Percent_Identity=48.4662576687117, Blast_Score=155, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 27212; Mature: 27212

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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CCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]