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The map label for this gene is glmS [H]

Identifier: 55981865

GI number: 55981865

Start: 1781934

End: 1783748

Strand: Direct

Name: glmS [H]

Synonym: TTHA1896

Alternate gene names: 55981865

Gene position: 1781934-1783748 (Clockwise)

Preceding gene: 55981864

Following gene: 55981866

Centisome position: 96.33

GC content: 70.25

Gene sequence:

>1815_bases
ATGTGCGGGATCGTAGGCTACGTAGGTTTTAGGAACGCGACGGACGTGCTTTTGGACGGGCTCCGGCGCCTGGAGTATAG
GGGGTACGACTCCGCCGGCATTGCGGTGCGGACCCCGGAGGGCCTCAAGGTGGTGAAGCGCTCGGGGAAGCTCTCCGCCC
TGGCAGAGGCCGTGGGGAAGACGCCCCTCCAGGGGGCCTTGGGCATCGGCCACACCCGCTGGGCCACCCACGGGGCCCCC
ACGGACCCGAACGCCCACCCCCACACCACGGAGGACGGGAGGATCGCCCTCATCCACAACGGCATCTTTGAGAACTACCT
GGAGCTCAAGGAGGCCCTGGAGGCCCGGGGGCACCGCTTCCGGTCGGAGACGGACACCGAGGTCCTCGCCCACCTCCTGG
AGGAAACCTACCGAGGCGACCTCCTTGAGGCCCTGCGGGAGGCCCTCAAGGCGGTGCGCGGGGCCTACGCCGTGGTGGTG
GCCCACGAGGACCACGAGGAGATCGTGGCCGCCCGCACGGTGAGCCCCCTGGTGGTGGGCCTGGGGGAGGGGGAGAACTT
CCTGGCCTCGGACGTGCCCGCCCTCCTCCCCTACACCCGCCGGGTCCTCTTCCTGCACGACGGGGACGTGGTGCGCCTCA
CCCGGGAGGGGGTGGAGATCACCGACCTGGAGGGCAGGCCGGTCCAGAGGGAGGCGGTGGAGGTGGACTGGACCCTGGAG
GCCGCCGAGAAGGGGGGCTTCCCCCACTACATGCTGAAGGAGATCTACGAGCAACCCTGGGTCCTGGAGAACACCCTGGG
CGGGCGCCTGAGGGAGGAGGAGGGGACCGTGGAGCTCGGCCTCGCCCTGGACCCACGGGAGGTGGACCGGGTCCACGTCA
TCGCCTGCGGAACGGCGAGCTACGCCGGGCTTTACGGGAAGTACCTCCTGGAGACCCTGGCCCGCCTCCCCACCGAGTGG
GACGTGGCCAGCGAGTACCGCTACCGCGACCCCGTGGTGGACTCGAGGACCCTCGCCCTCGCCATCAGCCAGTCGGGGGA
GACCATAGACACCCTGGAGGGCCTGAGGGAGGCCAAGCGCAAGGGGGCCCGCTCCCTCGGGGTCATCAACGCCAAGGGGA
GCACCCTGACGCGGGAGGTGGAGGACGTCCTCTACATCCACGCCGGGCCGGAGATCGGGGTGGCCTCCACCAAGGCCTAC
ACGGCCATGCTCGCGGCCATGGCCCTCCTCGCCGTCTGGTTCGGCCGGGGCCGGGGCGCCCTCGCCCTCGAGGAGGCCCA
ACGCCTCCTCCGGGAGATGCGCCGCCTCCCCAGGCTCGTGGAGGAGGTCTTGGAGAAAAGGCCCCTCGTGGCCCACGTGG
CCGAGAAGTACCACCAGGCCCGGGACTTCCTCTTCCTGGGGCGGCACGTCCAGGCCCCCACCGCCTACGAGGGGGCGCTG
AAGCTCAAGGAGATCAGCTACATCCACGCCGAGGCCTACCCCGCCGGGGAGATGAAGCACGGGCCCATCGCCCTCATTGA
CGAGCACCTCCCCGTGGTCGTCCTCGCCACCAAAGGCCCCCTCTACGAGAAGACCCTCTCCAACATCCAGGAGGTGCGGG
CCCGGGGCGGGAAGGTGATCGCCATCGCCACCGAGGGGGACGAGGAGATCCCGAGGCTCGCCCAGGACGTGATCTACGTC
CCCGAGGTCCACCCCCTCCTCGCCCCCATCGTGAGCGTGGTCCCCCTCCAGCTCCTCGCCTACGAGATCGCCGTGCTCCT
GGGGCGGGACGTGGACCAGCCCCGCAACCTGGCCAAGAGCGTGACCGTGGAGTGA

Upstream 100 bases:

>100_bases
CGGACAACCGAGGGGCAGGGCGTATCCAGAGGGAAACCGCCGGGAAGAAGGCGCAGCCCTTGGGGGCTTCGGCCCCTTCC
CGGTGGCCTTTTGAGGCCAT

Downstream 100 bases:

>100_bases
GGCTTGGCCTTCCCGCCGGGGGTGTGCTATGATCCCCCTTGGCGGGGGCCGTTAGCTCAACTGGCAGAGCACCGGTCTCC
AAAACCGGGGGTTGGAGGTT

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MCGIVGYVGFRNATDVLLDGLRRLEYRGYDSAGIAVRTPEGLKVVKRSGKLSALAEAVGKTPLQGALGIGHTRWATHGAP
TDPNAHPHTTEDGRIALIHNGIFENYLELKEALEARGHRFRSETDTEVLAHLLEETYRGDLLEALREALKAVRGAYAVVV
AHEDHEEIVAARTVSPLVVGLGEGENFLASDVPALLPYTRRVLFLHDGDVVRLTREGVEITDLEGRPVQREAVEVDWTLE
AAEKGGFPHYMLKEIYEQPWVLENTLGGRLREEEGTVELGLALDPREVDRVHVIACGTASYAGLYGKYLLETLARLPTEW
DVASEYRYRDPVVDSRTLALAISQSGETIDTLEGLREAKRKGARSLGVINAKGSTLTREVEDVLYIHAGPEIGVASTKAY
TAMLAAMALLAVWFGRGRGALALEEAQRLLREMRRLPRLVEEVLEKRPLVAHVAEKYHQARDFLFLGRHVQAPTAYEGAL
KLKEISYIHAEAYPAGEMKHGPIALIDEHLPVVVLATKGPLYEKTLSNIQEVRARGGKVIAIATEGDEEIPRLAQDVIYV
PEVHPLLAPIVSVVPLQLLAYEIAVLLGRDVDQPRNLAKSVTVE

Sequences:

>Translated_604_residues
MCGIVGYVGFRNATDVLLDGLRRLEYRGYDSAGIAVRTPEGLKVVKRSGKLSALAEAVGKTPLQGALGIGHTRWATHGAP
TDPNAHPHTTEDGRIALIHNGIFENYLELKEALEARGHRFRSETDTEVLAHLLEETYRGDLLEALREALKAVRGAYAVVV
AHEDHEEIVAARTVSPLVVGLGEGENFLASDVPALLPYTRRVLFLHDGDVVRLTREGVEITDLEGRPVQREAVEVDWTLE
AAEKGGFPHYMLKEIYEQPWVLENTLGGRLREEEGTVELGLALDPREVDRVHVIACGTASYAGLYGKYLLETLARLPTEW
DVASEYRYRDPVVDSRTLALAISQSGETIDTLEGLREAKRKGARSLGVINAKGSTLTREVEDVLYIHAGPEIGVASTKAY
TAMLAAMALLAVWFGRGRGALALEEAQRLLREMRRLPRLVEEVLEKRPLVAHVAEKYHQARDFLFLGRHVQAPTAYEGAL
KLKEISYIHAEAYPAGEMKHGPIALIDEHLPVVVLATKGPLYEKTLSNIQEVRARGGKVIAIATEGDEEIPRLAQDVIYV
PEVHPLLAPIVSVVPLQLLAYEIAVLLGRDVDQPRNLAKSVTVE
>Mature_604_residues
MCGIVGYVGFRNATDVLLDGLRRLEYRGYDSAGIAVRTPEGLKVVKRSGKLSALAEAVGKTPLQGALGIGHTRWATHGAP
TDPNAHPHTTEDGRIALIHNGIFENYLELKEALEARGHRFRSETDTEVLAHLLEETYRGDLLEALREALKAVRGAYAVVV
AHEDHEEIVAARTVSPLVVGLGEGENFLASDVPALLPYTRRVLFLHDGDVVRLTREGVEITDLEGRPVQREAVEVDWTLE
AAEKGGFPHYMLKEIYEQPWVLENTLGGRLREEEGTVELGLALDPREVDRVHVIACGTASYAGLYGKYLLETLARLPTEW
DVASEYRYRDPVVDSRTLALAISQSGETIDTLEGLREAKRKGARSLGVINAKGSTLTREVEDVLYIHAGPEIGVASTKAY
TAMLAAMALLAVWFGRGRGALALEEAQRLLREMRRLPRLVEEVLEKRPLVAHVAEKYHQARDFLFLGRHVQAPTAYEGAL
KLKEISYIHAEAYPAGEMKHGPIALIDEHLPVVVLATKGPLYEKTLSNIQEVRARGGKVIAIATEGDEEIPRLAQDVIYV
PEVHPLLAPIVSVVPLQLLAYEIAVLLGRDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=687, Percent_Identity=36.6812227074236, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI205277386, Length=686, Percent_Identity=36.5889212827988, Blast_Score=404, Evalue=1e-113,
Organism=Homo sapiens, GI29570798, Length=271, Percent_Identity=26.5682656826568, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1790167, Length=612, Percent_Identity=48.6928104575163, Blast_Score=544, Evalue=1e-156,
Organism=Escherichia coli, GI1788651, Length=241, Percent_Identity=31.9502074688797, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87082251, Length=319, Percent_Identity=22.257053291536, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17532899, Length=503, Percent_Identity=36.779324055666, Blast_Score=285, Evalue=7e-77,
Organism=Caenorhabditis elegans, GI17532897, Length=504, Percent_Identity=36.7063492063492, Blast_Score=283, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17539970, Length=502, Percent_Identity=35.8565737051793, Blast_Score=276, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6322745, Length=432, Percent_Identity=36.8055555555556, Blast_Score=270, Evalue=5e-73,
Organism=Saccharomyces cerevisiae, GI6323731, Length=434, Percent_Identity=30.6451612903226, Blast_Score=212, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6323730, Length=205, Percent_Identity=36.0975609756098, Blast_Score=126, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6323958, Length=174, Percent_Identity=31.6091954022989, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357745, Length=688, Percent_Identity=36.046511627907, Blast_Score=424, Evalue=1e-119,
Organism=Drosophila melanogaster, GI28573187, Length=263, Percent_Identity=28.8973384030418, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24659598, Length=238, Percent_Identity=28.1512605042017, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24659604, Length=238, Percent_Identity=28.1512605042017, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 66486; Mature: 66486

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGYVGFRNATDVLLDGLRRLEYRGYDSAGIAVRTPEGLKVVKRSGKLSALAEAVGK
CCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHCCCHHHHHHHHCC
TPLQGALGIGHTRWATHGAPTDPNAHPHTTEDGRIALIHNGIFENYLELKEALEARGHRF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCC
RSETDTEVLAHLLEETYRGDLLEALREALKAVRGAYAVVVAHEDHEEIVAARTVSPLVVG
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCEEEE
LGEGENFLASDVPALLPYTRRVLFLHDGDVVRLTREGVEITDLEGRPVQREAVEVDWTLE
CCCCCCCHHHCCHHHCCCCCEEEEEECCCEEEEEECCCEEEECCCCCCCCHHEEEEEEEE
AAEKGGFPHYMLKEIYEQPWVLENTLGGRLREEEGTVELGLALDPREVDRVHVIACGTAS
HHHCCCCCHHHHHHHHHCCCEEECCCCCCEECCCCCEEEEEEECCCCCCEEEEEEECCHH
YAGLYGKYLLETLARLPTEWDVASEYRYRDPVVDSRTLALAISQSGETIDTLEGLREAKR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
KGARSLGVINAKGSTLTREVEDVLYIHAGPEIGVASTKAYTAMLAAMALLAVWFGRGRGA
CCCCCEEEEECCCCHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
LALEEAQRLLREMRRLPRLVEEVLEKRPLVAHVAEKYHQARDFLFLGRHVQAPTAYEGAL
EEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCE
KLKEISYIHAEAYPAGEMKHGPIALIDEHLPVVVLATKGPLYEKTLSNIQEVRARGGKVI
EHHHHHEEECCCCCCCCCCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEE
AIATEGDEEIPRLAQDVIYVPEVHPLLAPIVSVVPLQLLAYEIAVLLGRDVDQPRNLAKS
EEEECCCHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VTVE
CCCC
>Mature Secondary Structure
MCGIVGYVGFRNATDVLLDGLRRLEYRGYDSAGIAVRTPEGLKVVKRSGKLSALAEAVGK
CCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHCCCHHHHHHHHCC
TPLQGALGIGHTRWATHGAPTDPNAHPHTTEDGRIALIHNGIFENYLELKEALEARGHRF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCC
RSETDTEVLAHLLEETYRGDLLEALREALKAVRGAYAVVVAHEDHEEIVAARTVSPLVVG
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCEEEE
LGEGENFLASDVPALLPYTRRVLFLHDGDVVRLTREGVEITDLEGRPVQREAVEVDWTLE
CCCCCCCHHHCCHHHCCCCCEEEEEECCCEEEEEECCCEEEECCCCCCCCHHEEEEEEEE
AAEKGGFPHYMLKEIYEQPWVLENTLGGRLREEEGTVELGLALDPREVDRVHVIACGTAS
HHHCCCCCHHHHHHHHHCCCEEECCCCCCEECCCCCEEEEEEECCCCCCEEEEEEECCHH
YAGLYGKYLLETLARLPTEWDVASEYRYRDPVVDSRTLALAISQSGETIDTLEGLREAKR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
KGARSLGVINAKGSTLTREVEDVLYIHAGPEIGVASTKAYTAMLAAMALLAVWFGRGRGA
CCCCCEEEEECCCCHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
LALEEAQRLLREMRRLPRLVEEVLEKRPLVAHVAEKYHQARDFLFLGRHVQAPTAYEGAL
EEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCE
KLKEISYIHAEAYPAGEMKHGPIALIDEHLPVVVLATKGPLYEKTLSNIQEVRARGGKVI
EHHHHHEEECCCCCCCCCCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEE
AIATEGDEEIPRLAQDVIYVPEVHPLLAPIVSVVPLQLLAYEIAVLLGRDVDQPRNLAKS
EEEECCCHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VTVE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA