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The map label for this gene is dnaX [C]

Identifier: 55981829

GI number: 55981829

Start: 1743712

End: 1744518

Strand: Reverse

Name: dnaX [C]

Synonym: TTHA1860

Alternate gene names: 55981829

Gene position: 1744518-1743712 (Counterclockwise)

Preceding gene: 55981830

Following gene: 55981828

Centisome position: 94.31

GC content: 73.85

Gene sequence:

>807_bases
ATGGCTCTACACCCGGCTCACCCTGGGGCAATAATCGGGCACGAGGCCGTTCTCGCCCTCCTTCCCCGCCTCACCGCCCA
GACCCTGCTCTTCTCCGGCCCCGAGGGGGTGGGGCGGCGCACCGTGGCCCGCTGGTACGCCTGGGGGCTCAACCGCGGCT
TCCCCCCGCCCTCCCTGGGGGAGCACCCGGACGTCCTCGAGGTGGGGCCCAAGGCCCGGGACCTCCGGGGCCGGGCCGAG
GTGCGGCTGGAGGAGGTGGCGCCCCTCTTGGAGTGGTGCTCCAGCCACCCCCGGGAGCGGGTGAAGGTGGCCATCCTGGA
CTCGGCCCACCTCCTCACCGAGGCCGCGGCCAACGCCCTCCTCAAGCTCCTGGAGGAGCCCCCTTCCTACGCCCGCATCG
TCCTCATCGCCCCAAGCCGCGCCACCCTCCTCCCCACCCTGGCCTCCCGGGCCACGGAGGTGGCCTTCGCCCCCGTGCCC
GAGGAGGCCCTGCGCGCCCTCACCCAGGACCCGGAGCTCCTCCGCTACGCCGCCGGGGCCCCGGGCCGCCTCCTTAGGGC
CCTCCAGGACCCGGAGGGGTACCGGGCCCGCATGGCCAGGGCGCAAAGGGTCCTGAAAGCCCCGCCCCTGGAGCGCCTCG
CTTTGCTTCGGGAGCTTTTGGCCGAGGAGGAGGGGGTCCACGCCCTCCACGCCGTCCTAAAGCGCCCGGAGCACCTCCTT
GCCCTGGAGCGGGCGCGGGAGGCCCTGGAGGGGTACGTGAGCCCCGAGCTGGTCCTCGCCCGGCTGGCCTTAGACTTAGA
GACATGA

Upstream 100 bases:

>100_bases
CGGCCTTCGCCCTTTGGGAGGGGGACCGGATCGCCTTCTACCGGGTGGCCTACGACCTGGAGCGCGTGGCCGCCCGCCTT
GCGGAGGAGGGCTTTCCCCC

Downstream 100 bases:

>100_bases
CCGTGGGCGTACGCTTCCGCACCCCCGTCCTCCGCTACGTCCGCTTCCGGGGGGAGGCCCCGCCCGTGGACGCCTTCGTG
GTGGTCCGCACCGGGCGGGG

Product: DNA polymerase III subunit delta'

Products: N Pyrophosphate; DNA(N). [C]

Alternate protein names: DNA Polymerase III Subunit; DNA Polymerase III Subunits Gamma/Tau

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MALHPAHPGAIIGHEAVLALLPRLTAQTLLFSGPEGVGRRTVARWYAWGLNRGFPPPSLGEHPDVLEVGPKARDLRGRAE
VRLEEVAPLLEWCSSHPRERVKVAILDSAHLLTEAAANALLKLLEEPPSYARIVLIAPSRATLLPTLASRATEVAFAPVP
EEALRALTQDPELLRYAAGAPGRLLRALQDPEGYRARMARAQRVLKAPPLERLALLRELLAEEEGVHALHAVLKRPEHLL
ALERAREALEGYVSPELVLARLALDLET

Sequences:

>Translated_268_residues
MALHPAHPGAIIGHEAVLALLPRLTAQTLLFSGPEGVGRRTVARWYAWGLNRGFPPPSLGEHPDVLEVGPKARDLRGRAE
VRLEEVAPLLEWCSSHPRERVKVAILDSAHLLTEAAANALLKLLEEPPSYARIVLIAPSRATLLPTLASRATEVAFAPVP
EEALRALTQDPELLRYAAGAPGRLLRALQDPEGYRARMARAQRVLKAPPLERLALLRELLAEEEGVHALHAVLKRPEHLL
ALERAREALEGYVSPELVLARLALDLET
>Mature_267_residues
ALHPAHPGAIIGHEAVLALLPRLTAQTLLFSGPEGVGRRTVARWYAWGLNRGFPPPSLGEHPDVLEVGPKARDLRGRAEV
RLEEVAPLLEWCSSHPRERVKVAILDSAHLLTEAAANALLKLLEEPPSYARIVLIAPSRATLLPTLASRATEVAFAPVPE
EALRALTQDPELLRYAAGAPGRLLRALQDPEGYRARMARAQRVLKAPPLERLALLRELLAEEEGVHALHAVLKRPEHLLA
LERAREALEGYVSPELVLARLALDLET

Specific function: DNA Polymerase III Is A Complex, Multichain Enzyme Responsible For Most Of The Replicative Synthesis In Bacteria. This DNA Polymerase Also Exhibits 3' To 5' Exonuclease Activity. The Tau Chain Serves As A Scaffold To Help In The Dimerizaton Of The Core Co

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=174, Percent_Identity=29.3103448275862, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.7 [C]

Molecular weight: Translated: 29340; Mature: 29209

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALHPAHPGAIIGHEAVLALLPRLTAQTLLFSGPEGVGRRTVARWYAWGLNRGFPPPSLG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
EHPDVLEVGPKARDLRGRAEVRLEEVAPLLEWCSSHPRERVKVAILDSAHLLTEAAANAL
CCCCHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCHHHEEEEEECHHHHHHHHHHHHH
LKLLEEPPSYARIVLIAPSRATLLPTLASRATEVAFAPVPEEALRALTQDPELLRYAAGA
HHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHEECCCCHHHHHHHCCCHHHHHHHCCC
PGRLLRALQDPEGYRARMARAQRVLKAPPLERLALLRELLAEEEGVHALHAVLKRPEHLL
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHH
ALERAREALEGYVSPELVLARLALDLET
HHHHHHHHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALHPAHPGAIIGHEAVLALLPRLTAQTLLFSGPEGVGRRTVARWYAWGLNRGFPPPSLG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
EHPDVLEVGPKARDLRGRAEVRLEEVAPLLEWCSSHPRERVKVAILDSAHLLTEAAANAL
CCCCHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCHHHEEEEEECHHHHHHHHHHHHH
LKLLEEPPSYARIVLIAPSRATLLPTLASRATEVAFAPVPEEALRALTQDPELLRYAAGA
HHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHEECCCCHHHHHHHCCCHHHHHHHCCC
PGRLLRALQDPEGYRARMARAQRVLKAPPLERLALLRELLAEEEGVHALHAVLKRPEHLL
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHH
ALERAREALEGYVSPELVLARLALDLET
HHHHHHHHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Dimethyl sulfoxide epsilon,; Polymerase alpha accessory factors; Proliferating cell nuclear antigen; Replication factor A; Replication factor C; Thiol [C]

Metal ions: K+; Mg2+; Mn2+; Na+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.0063 {dATP}} [C]

Substrates: N Deoxynucleoside Triphosphate; DNA [C]

Specific reaction: N Deoxynucleoside Triphosphate = N Pyrophosphate + DNA(N). Protein + DNA = Protein-DNA [C]

General reaction: Nucleotidyl group transfer [C]

Inhibitor: 1, 10-Phenanthroline; 2', 3'-Dideoxythymidine5'-triphosphate polymerase beta, gamma, delta, epsilon; Aphidicolin polymerase alpha; Ara-ATP; Ara-CTP; Benzyl oxycarbonyl -Leu-Leu-al; Carbonyl diphosphonate delta, alpha,; Dideoxynucleoside 5'-triphosphate;

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA