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The map label for this gene is ygbD [C]

Identifier: 55981804

GI number: 55981804

Start: 1716984

End: 1718315

Strand: Direct

Name: ygbD [C]

Synonym: TTHA1835

Alternate gene names: 55981804

Gene position: 1716984-1718315 (Clockwise)

Preceding gene: 55981803

Following gene: 55981805

Centisome position: 92.82

GC content: 71.47

Gene sequence:

>1332_bases
ATGGGCAAGCGGATGGTGGTCGTGGGCGGGGTGGCGGGCGGCGCCTCCGCCGCCGCCAAGGCCAAGCGGGAAAACCCCGA
GCTGGAGGTGGTGGTCTACGAGAAGTCGGGGTGGGTTTCCTACGGGGCCTGCGGCCTGCCCTACGTGCTTTCCGGGGAGA
TCCCCCGCCTGGAAAGGCTGGTGGCCCGCACCCCCGAGGAGTTCCGGAAGCAGGGGGTTCTGGTCCGCACCCGCCACGAG
GTGGTGGACGTGGACTACGAGCTCCGCACCCTGACGGTGCACGACCACGCCGAGGGAAGGACCTTCCAGGACCGGTTTGA
CCACCTGGTCCTGGCCACGGGGGCGCGGCCCAGCCTCCCCCCCATCCCCGGCACGGAGCAGGAAGGGGTCTACACCCTGA
GGACCATGGAGGACGGGGAGCGGCTCCTGAAGGCCCTCCCCCAAGCCCGGCGGGCCGCCATCCTGGGGGCGGGGTACATC
GGCCTCGAGGCCGCCGAGGCCTTCCGCAAGCGGGGCCTGCAGGTGACCCTCCTGGAGGCCAAGGACCGCCCCCTCCCCCA
CTGGGACCCGGAGGTGGGCGCCCTCCTCAAGGAGGAGCTGGAGCGGCACGGGGTGGAGGTCTGGACCGGGGTGAAGGTGG
AGGCCTTCCGGGGCATGGGCCGGGTGGAGGCGGTGGAGACCTCGGAAGGCGTGGTGCCCGCCGACTTGGTCCTCCTCGCC
ACGGGGATCCGGCCCAACACCGAGCTCGCCCAGGCCATGGGGGTGGCCTTGGGCCCCACCGGGGCCATCGCCACCGACGA
AAGGATGCGCACCAACCTGGAAGGGGTCTACGCCGCCGGGGACGTGGCGGAAAGCTTCCACCGGGTCCTCAAGCGCCCCT
ACTGGCTTCCCTTGGGGGACGTGGCCAACAAGCACGGCCGCACCGCGGGAAGCGTCATCGCCGGCAGGGAGGCCCGCTTT
CTGGGCGTGGTGGGCACGGCCATCTTCAAGGCCTTTGACCTGGCCGTGGCCACCACGGGGCTTTCCCTGGAAGGGGCCCT
AAAGGAGGGGTTCTGGGCCAAGAAGGTCTTCATCCAGAGCCGGGATGGGGCCCACTACTACCCGGGAAGCGGGCCCCTCT
GGGTGGAGCTCGTCTACGAGGAGGGGACGGGGAGGCTTTTGGGCGGCGCGGTGGTGGCCCGGGGGCACGGGGCCCTGCGC
ATAGACGTCCTCGCCGCCCTCCTCCACCGGGAGGGGAGCGTGGAGGACCTTTTGGCCCTGGACCTGGCCTACGCCCCGCC
CTTTAGCCCCGTCTGGGACCCCCTCCTCATCGCCGCCCAGCAGGCCCGCTAA

Upstream 100 bases:

>100_bases
ATCTGAAGGGCGGGCGGCTCGTGCGGGAGGAAACCCCCAAGGCCAAGGGCTAAGGCCTCTGGGGCATTCCGCCCACCCCT
TCTGTGGCAGAATACCCCCC

Downstream 100 bases:

>100_bases
GCGCCCCGTGGGGCCAAACCGAGGTGGGGGCGCCTATCCGGTGTAAACCCGGGCGAAACACACCAAAAGGCCGTGTCAAG
CCCGGGCGGCTACACCCTAC

Product: NADH oxidase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MGKRMVVVGGVAGGASAAAKAKRENPELEVVVYEKSGWVSYGACGLPYVLSGEIPRLERLVARTPEEFRKQGVLVRTRHE
VVDVDYELRTLTVHDHAEGRTFQDRFDHLVLATGARPSLPPIPGTEQEGVYTLRTMEDGERLLKALPQARRAAILGAGYI
GLEAAEAFRKRGLQVTLLEAKDRPLPHWDPEVGALLKEELERHGVEVWTGVKVEAFRGMGRVEAVETSEGVVPADLVLLA
TGIRPNTELAQAMGVALGPTGAIATDERMRTNLEGVYAAGDVAESFHRVLKRPYWLPLGDVANKHGRTAGSVIAGREARF
LGVVGTAIFKAFDLAVATTGLSLEGALKEGFWAKKVFIQSRDGAHYYPGSGPLWVELVYEEGTGRLLGGAVVARGHGALR
IDVLAALLHREGSVEDLLALDLAYAPPFSPVWDPLLIAAQQAR

Sequences:

>Translated_443_residues
MGKRMVVVGGVAGGASAAAKAKRENPELEVVVYEKSGWVSYGACGLPYVLSGEIPRLERLVARTPEEFRKQGVLVRTRHE
VVDVDYELRTLTVHDHAEGRTFQDRFDHLVLATGARPSLPPIPGTEQEGVYTLRTMEDGERLLKALPQARRAAILGAGYI
GLEAAEAFRKRGLQVTLLEAKDRPLPHWDPEVGALLKEELERHGVEVWTGVKVEAFRGMGRVEAVETSEGVVPADLVLLA
TGIRPNTELAQAMGVALGPTGAIATDERMRTNLEGVYAAGDVAESFHRVLKRPYWLPLGDVANKHGRTAGSVIAGREARF
LGVVGTAIFKAFDLAVATTGLSLEGALKEGFWAKKVFIQSRDGAHYYPGSGPLWVELVYEEGTGRLLGGAVVARGHGALR
IDVLAALLHREGSVEDLLALDLAYAPPFSPVWDPLLIAAQQAR
>Mature_442_residues
GKRMVVVGGVAGGASAAAKAKRENPELEVVVYEKSGWVSYGACGLPYVLSGEIPRLERLVARTPEEFRKQGVLVRTRHEV
VDVDYELRTLTVHDHAEGRTFQDRFDHLVLATGARPSLPPIPGTEQEGVYTLRTMEDGERLLKALPQARRAAILGAGYIG
LEAAEAFRKRGLQVTLLEAKDRPLPHWDPEVGALLKEELERHGVEVWTGVKVEAFRGMGRVEAVETSEGVVPADLVLLAT
GIRPNTELAQAMGVALGPTGAIATDERMRTNLEGVYAAGDVAESFHRVLKRPYWLPLGDVANKHGRTAGSVIAGREARFL
GVVGTAIFKAFDLAVATTGLSLEGALKEGFWAKKVFIQSRDGAHYYPGSGPLWVELVYEEGTGRLLGGAVVARGHGALRI
DVLAALLHREGSVEDLLALDLAYAPPFSPVWDPLLIAAQQAR

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=344, Percent_Identity=29.0697674418605, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI226437568, Length=344, Percent_Identity=29.0697674418605, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI65787454, Length=344, Percent_Identity=29.0697674418605, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI50301238, Length=192, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1789065, Length=301, Percent_Identity=27.5747508305648, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789915, Length=180, Percent_Identity=35, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789765, Length=232, Percent_Identity=28.448275862069, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788892, Length=182, Percent_Identity=32.4175824175824, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786307, Length=315, Percent_Identity=26.984126984127, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081717, Length=178, Percent_Identity=30.3370786516854, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17559934, Length=262, Percent_Identity=25.5725190839695, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17557007, Length=292, Percent_Identity=28.4246575342466, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585130, Length=349, Percent_Identity=24.9283667621776, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24639257, Length=316, Percent_Identity=24.6835443037975, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI281359715, Length=316, Percent_Identity=24.6835443037975, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI281359713, Length=316, Percent_Identity=24.6835443037975, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24639250, Length=316, Percent_Identity=24.6835443037975, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI18543267, Length=316, Percent_Identity=24.6835443037975, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24639252, Length=316, Percent_Identity=24.6835443037975, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 47876; Mature: 47745

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKRMVVVGGVAGGASAAAKAKRENPELEVVVYEKSGWVSYGACGLPYVLSGEIPRLERL
CCCEEEEEECCCCCCHHHHHHHCCCCCEEEEEEECCCCEEECCCCCCEEECCCCHHHHHH
VARTPEEFRKQGVLVRTRHEVVDVDYELRTLTVHDHAEGRTFQDRFDHLVLATGARPSLP
HHCCCHHHHHCCCEEEECCCEEECCEEEEEEEEECCCCCCCHHHHHCEEEEEECCCCCCC
PIPGTEQEGVYTLRTMEDGERLLKALPQARRAAILGAGYIGLEAAEAFRKRGLQVTLLEA
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHCCCEEEEEEC
KDRPLPHWDPEVGALLKEELERHGVEVWTGVKVEAFRGMGRVEAVETSEGVVPADLVLLA
CCCCCCCCCHHHHHHHHHHHHHCCCEEEECCEEHHHCCCCCEEEEECCCCCCCCEEEEEE
TGIRPNTELAQAMGVALGPTGAIATDERMRTNLEGVYAAGDVAESFHRVLKRPYWLPLGD
ECCCCCHHHHHHHCCEECCCCCCCCCHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCCCHH
VANKHGRTAGSVIAGREARFLGVVGTAIFKAFDLAVATTGLSLEGALKEGFWAKKVFIQS
HHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHHHCCCEEEEEEEEC
RDGAHYYPGSGPLWVELVYEEGTGRLLGGAVVARGHGALRIDVLAALLHREGSVEDLLAL
CCCCEECCCCCCEEEEEEEECCCCEEECCEEEECCCCCCHHHHHHHHHHCCCCHHHHHHH
DLAYAPPFSPVWDPLLIAAQQAR
HHHCCCCCCCCCCHHHHHCCCCC
>Mature Secondary Structure 
GKRMVVVGGVAGGASAAAKAKRENPELEVVVYEKSGWVSYGACGLPYVLSGEIPRLERL
CCEEEEEECCCCCCHHHHHHHCCCCCEEEEEEECCCCEEECCCCCCEEECCCCHHHHHH
VARTPEEFRKQGVLVRTRHEVVDVDYELRTLTVHDHAEGRTFQDRFDHLVLATGARPSLP
HHCCCHHHHHCCCEEEECCCEEECCEEEEEEEEECCCCCCCHHHHHCEEEEEECCCCCCC
PIPGTEQEGVYTLRTMEDGERLLKALPQARRAAILGAGYIGLEAAEAFRKRGLQVTLLEA
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHCCCEEEEEEC
KDRPLPHWDPEVGALLKEELERHGVEVWTGVKVEAFRGMGRVEAVETSEGVVPADLVLLA
CCCCCCCCCHHHHHHHHHHHHHCCCEEEECCEEHHHCCCCCEEEEECCCCCCCCEEEEEE
TGIRPNTELAQAMGVALGPTGAIATDERMRTNLEGVYAAGDVAESFHRVLKRPYWLPLGD
ECCCCCHHHHHHHCCEECCCCCCCCCHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCCCHH
VANKHGRTAGSVIAGREARFLGVVGTAIFKAFDLAVATTGLSLEGALKEGFWAKKVFIQS
HHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHHHCCCEEEEEEEEC
RDGAHYYPGSGPLWVELVYEEGTGRLLGGAVVARGHGALRIDVLAALLHREGSVEDLLAL
CCCCEECCCCCCEEEEEEEECCCCEEECCEEEECCCCCCHHHHHHHHHHCCCCHHHHHHH
DLAYAPPFSPVWDPLLIAAQQAR
HHHCCCCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA