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The map label for this gene is fabZ

Identifier: 55981784

GI number: 55981784

Start: 1698449

End: 1698877

Strand: Reverse

Name: fabZ

Synonym: TTHA1815

Alternate gene names: 55981784

Gene position: 1698877-1698449 (Counterclockwise)

Preceding gene: 55981785

Following gene: 55981783

Centisome position: 91.84

GC content: 72.03

Gene sequence:

>429_bases
GTGGACATCCGGGAGATCCTCAAGGTCCTGCCCCATCGCTACCCCTTTCTCCTCGTGGACCGGGTGCTGGAGGCGGACGA
GAGGCGCTTCAAGGCCCTCAAGAACGTGACCTTCAACGAGCCCCACTTCCAGGGGCACTTCCCCGGCCACCCCGTCATGC
CCGGGGTGCTGATCCTGGAGGCCATGGCCCAGGCGGCCGTGGGGGCGCTGGTGCGCCAGCCGGGCTTTCCCCAAGGGGGC
CTCGCCTTCCTCGCCGGGGTGGAGGGGGCCCGGTTCCGGCGGCCCGTCTACCCGGGGGACACCCTGATCCTCGAGGGGGA
GCTCCTCGCCTTCCGCCGGGGCGTGGGCAAGGTGGCGGTGCGGGCCCTGGTGGAGGGGGAGGAGCGGGCGAGCGCCACCC
TGACCTTCGTCCTCCAGGGGGCCTCTTGA

Upstream 100 bases:

>100_bases
TGAGGCCGTGGCCCTGGGCACTGGGAAGGCCCTGGAGATGCTCCACGTCCTCGAGGACACCATCCTCTCCTCCGACGACG
TCCTGAGGAGGTGAGGCCCT

Downstream 100 bases:

>100_bases
TGGCGGACCTGGAGCGCTACCTCAAGCGGGCCCGGGGCGGCCGGGTGGTGCGCACGGGCTTCCTGGACCCCGAGGACCAG
GCCCGCCTGGAGGAGATGGC

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MDIREILKVLPHRYPFLLVDRVLEADERRFKALKNVTFNEPHFQGHFPGHPVMPGVLILEAMAQAAVGALVRQPGFPQGG
LAFLAGVEGARFRRPVYPGDTLILEGELLAFRRGVGKVAVRALVEGEERASATLTFVLQGAS

Sequences:

>Translated_142_residues
MDIREILKVLPHRYPFLLVDRVLEADERRFKALKNVTFNEPHFQGHFPGHPVMPGVLILEAMAQAAVGALVRQPGFPQGG
LAFLAGVEGARFRRPVYPGDTLILEGELLAFRRGVGKVAVRALVEGEERASATLTFVLQGAS
>Mature_142_residues
MDIREILKVLPHRYPFLLVDRVLEADERRFKALKNVTFNEPHFQGHFPGHPVMPGVLILEAMAQAAVGALVRQPGFPQGG
LAFLAGVEGARFRRPVYPGDTLILEGELLAFRRGVGKVAVRALVEGEERASATLTFVLQGAS

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=136, Percent_Identity=52.9411764705882, Blast_Score=134, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_THET2 (Q72HM3)

Other databases:

- EMBL:   AE017221
- RefSeq:   YP_005432.1
- ProteinModelPortal:   Q72HM3
- SMR:   Q72HM3
- STRING:   Q72HM3
- GeneID:   2775152
- GenomeReviews:   AE017221_GR
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   NVSANES
- PhylomeDB:   Q72HM3
- ProtClustDB:   PRK00006
- BioCyc:   TTHE262724:TT_C1463-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.- [C]

Molecular weight: Translated: 15570; Mature: 15570

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: ACT_SITE 46-46

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIREILKVLPHRYPFLLVDRVLEADERRFKALKNVTFNEPHFQGHFPGHPVMPGVLILE
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
AMAQAAVGALVRQPGFPQGGLAFLAGVEGARFRRPVYPGDTLILEGELLAFRRGVGKVAV
HHHHHHHHHHHHCCCCCCCCHHHHHCCCCCHHCCCCCCCCEEEECCHHHHHHHCHHHHHH
RALVEGEERASATLTFVLQGAS
HHHHCCCHHCCEEEEEEEECCC
>Mature Secondary Structure
MDIREILKVLPHRYPFLLVDRVLEADERRFKALKNVTFNEPHFQGHFPGHPVMPGVLILE
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
AMAQAAVGALVRQPGFPQGGLAFLAGVEGARFRRPVYPGDTLILEGELLAFRRGVGKVAV
HHHHHHHHHHHHCCCCCCCCHHHHHCCCCCHHCCCCCCCCEEEECCHHHHHHHCHHHHHH
RALVEGEERASATLTFVLQGAS
HHHHCCCHHCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA