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The map label for this gene is ykuT [H]

Identifier: 55981684

GI number: 55981684

Start: 1608626

End: 1609693

Strand: Direct

Name: ykuT [H]

Synonym: TTHA1715

Alternate gene names: 55981684

Gene position: 1608626-1609693 (Clockwise)

Preceding gene: 55981682

Following gene: 55981685

Centisome position: 86.96

GC content: 69.57

Gene sequence:

>1068_bases
ATGCTGGCCGCGTTGCACATCGCCCTCACCCTGGCGGCAGTGGTCCTTTTGGGACGGCTCGGCGCGAGGCTTTTGGGGAG
GCTCGCCGCCCTCACCCCGAGCACCCGGGACGACGCCTTCTTCCGCCTCCTGGGCTACGCCTGGTGGGGGGTGGTGGCTG
TGGCCGGGGCAAGCTACCTGAGCCACGCCCTAAGCCTTCCCTACGAGCCCCTGGCCACCTGGGGGCGGAGCCTGGTGGCC
TGGCTCGGGGGGAAGGGGGTGGCCGGCGGGGCCGTCCTCCTCGCCACCTGGACGGCCTACCGCCTGGTGCCCCTCCTCCT
CAGGAGCCTCCCCTTGCCGGAGACGGAGGGGGAGCTCACCCGGCAGGCGGTGCGGGCCAAGACCCTGAGGAACGTCTCCG
AGTCGGCCCTGAAGGTTGCGGTGGTCACCGTGGGCGGCCTCCTCTTCCTCTCCAACCTCGGCCTCAACGTCACCGCCCTC
CTCGCCGGGGCCGGGGTGGCGGGGCTCGCCTTAAGCTTCGCCGCCCAGAACCTCATCCGCGACTTCATCAACGGCTTCTT
CATCCTCCTGGAAGACCAGTACGGCGTGGGGGACATCGTGAAGGTGGGGGACCTCGCCGGCGTGGTGGAGAAGTTCAACC
TGCGCCTCACCGTCCTCCGCGACCTCGAGGGCAAGGCCCACTTCATCCCCAACTCCCAGATCCAGCAGGTCACCGTCTTC
ACCCAGGAGTGGAGCCGGGCGGTGGTGGACGTGGGGGTGGCCTACAAGGAGGACGTGGACCGCGTCCTCGCCATCTTCCG
GGACGAGGCGGAGCGCTTCTTCCAGGACCCGGAGTGGCAGGACAAGCTCACGAACCCCCCGGAGGTCCTCGGCGTCGAAA
ACCTGGCCGACTCCGCCGTGGTCATCCGCACCCTCTTCGGCACCAAGCCCGCCCAGCAGTGGGCCGTGGCCCGGGAGTTC
CGCCGGCGGATCAAGAAGCGGCTGGACCAGGAGGGCGTGGAGATCCCCTTCCCCCACCGGACCCTCTACTTCGGGGAGCC
CCTGCGGGTGGTTAAGGAAACGCCATGA

Upstream 100 bases:

>100_bases
AGGCGGAAGTCGTGGAGGACGTGCCAGCCCTCGAGGGTGTGGGTGGGTTCGGGAACGTGCCGCTCCATCTCCCCCACTAT
AGCTCCGGTATACTTGGCCC

Downstream 100 bases:

>100_bases
GGGAAAGCCCTTACCGGATCCTGGAGGAAGCCCTCAGGCCCCACCTGGGGGCCCGGGCCCAGGTGGTCTTGGAGGAGGGG
CTCAAGCGGCTGGGCAAGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MLAALHIALTLAAVVLLGRLGARLLGRLAALTPSTRDDAFFRLLGYAWWGVVAVAGASYLSHALSLPYEPLATWGRSLVA
WLGGKGVAGGAVLLATWTAYRLVPLLLRSLPLPETEGELTRQAVRAKTLRNVSESALKVAVVTVGGLLFLSNLGLNVTAL
LAGAGVAGLALSFAAQNLIRDFINGFFILLEDQYGVGDIVKVGDLAGVVEKFNLRLTVLRDLEGKAHFIPNSQIQQVTVF
TQEWSRAVVDVGVAYKEDVDRVLAIFRDEAERFFQDPEWQDKLTNPPEVLGVENLADSAVVIRTLFGTKPAQQWAVAREF
RRRIKKRLDQEGVEIPFPHRTLYFGEPLRVVKETP

Sequences:

>Translated_355_residues
MLAALHIALTLAAVVLLGRLGARLLGRLAALTPSTRDDAFFRLLGYAWWGVVAVAGASYLSHALSLPYEPLATWGRSLVA
WLGGKGVAGGAVLLATWTAYRLVPLLLRSLPLPETEGELTRQAVRAKTLRNVSESALKVAVVTVGGLLFLSNLGLNVTAL
LAGAGVAGLALSFAAQNLIRDFINGFFILLEDQYGVGDIVKVGDLAGVVEKFNLRLTVLRDLEGKAHFIPNSQIQQVTVF
TQEWSRAVVDVGVAYKEDVDRVLAIFRDEAERFFQDPEWQDKLTNPPEVLGVENLADSAVVIRTLFGTKPAQQWAVAREF
RRRIKKRLDQEGVEIPFPHRTLYFGEPLRVVKETP
>Mature_355_residues
MLAALHIALTLAAVVLLGRLGARLLGRLAALTPSTRDDAFFRLLGYAWWGVVAVAGASYLSHALSLPYEPLATWGRSLVA
WLGGKGVAGGAVLLATWTAYRLVPLLLRSLPLPETEGELTRQAVRAKTLRNVSESALKVAVVTVGGLLFLSNLGLNVTAL
LAGAGVAGLALSFAAQNLIRDFINGFFILLEDQYGVGDIVKVGDLAGVVEKFNLRLTVLRDLEGKAHFIPNSQIQQVTVF
TQEWSRAVVDVGVAYKEDVDRVLAIFRDEAERFFQDPEWQDKLTNPPEVLGVENLADSAVVIRTLFGTKPAQQWAVAREF
RRRIKKRLDQEGVEIPFPHRTLYFGEPLRVVKETP

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=214, Percent_Identity=33.1775700934579, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786670, Length=255, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787591, Length=227, Percent_Identity=22.9074889867841, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789291, Length=201, Percent_Identity=26.865671641791, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI2367355, Length=208, Percent_Identity=25.4807692307692, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 38846; Mature: 38846

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAALHIALTLAAVVLLGRLGARLLGRLAALTPSTRDDAFFRLLGYAWWGVVAVAGASYL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SHALSLPYEPLATWGRSLVAWLGGKGVAGGAVLLATWTAYRLVPLLLRSLPLPETEGELT
HHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
RQAVRAKTLRNVSESALKVAVVTVGGLLFLSNLGLNVTALLAGAGVAGLALSFAAQNLIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHH
DFINGFFILLEDQYGVGDIVKVGDLAGVVEKFNLRLTVLRDLEGKAHFIPNSQIQQVTVF
HHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCEEECCCCCHHHHHHH
TQEWSRAVVDVGVAYKEDVDRVLAIFRDEAERFFQDPEWQDKLTNPPEVLGVENLADSAV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHCHHHHHHHHH
VIRTLFGTKPAQQWAVAREFRRRIKKRLDQEGVEIPFPHRTLYFGEPLRVVKETP
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHCCCC
>Mature Secondary Structure
MLAALHIALTLAAVVLLGRLGARLLGRLAALTPSTRDDAFFRLLGYAWWGVVAVAGASYL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SHALSLPYEPLATWGRSLVAWLGGKGVAGGAVLLATWTAYRLVPLLLRSLPLPETEGELT
HHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
RQAVRAKTLRNVSESALKVAVVTVGGLLFLSNLGLNVTALLAGAGVAGLALSFAAQNLIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHH
DFINGFFILLEDQYGVGDIVKVGDLAGVVEKFNLRLTVLRDLEGKAHFIPNSQIQQVTVF
HHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCEEECCCCCHHHHHHH
TQEWSRAVVDVGVAYKEDVDRVLAIFRDEAERFFQDPEWQDKLTNPPEVLGVENLADSAV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHCHHHHHHHHH
VIRTLFGTKPAQQWAVAREFRRRIKKRLDQEGVEIPFPHRTLYFGEPLRVVKETP
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]