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The map label for this gene is gufA [H]

Identifier: 55981675

GI number: 55981675

Start: 1601003

End: 1601749

Strand: Direct

Name: gufA [H]

Synonym: TTHA1706

Alternate gene names: 55981675

Gene position: 1601003-1601749 (Clockwise)

Preceding gene: 55981674

Following gene: 55981679

Centisome position: 86.55

GC content: 70.01

Gene sequence:

>747_bases
ATGGAAGGCCTGCCCATCACTCCCTGGACGGTGTTCCTCTACGCCTTCCTCACCGCCGTCGCCACAGGCCTCGGCGCCCT
CCCCTTCCTCTTCACCCGCGGGATCACGCGGCGGCACCTCGGCCTCGCCAACGCCGCCGCCGCCGGGCTCATGGTGGCGG
CGAGCTTCGGCCTGATCTACGAGGGGGTGAACTACAGCCTGGGGCGGACCCTGGTGGGCGTGGGCCTCGGCCTCCTCTTC
ATCCTCCTCGCCCACCGCTACCTCGAGGGCCGGGAGGTGAACCTCGGCGACCTCAAGGGCCTGGACGCCCGCAAGGCCCT
GATGATGGTGGGCATCATGACCCTTCACTCCTTCGCCGAAGGGGTGGGGGTGGGGGTGGCCTTCGGGGGCGGGGAGGCCC
TCGGGGTCTTCATCTCCTTGGCCATCGCCGTGCACAACATCCCCGAGGGACTCGCCATCAGCCTCGTCCTCGTTCCCCGG
GGGGTGAGCGTGCTCGGGGCCGCCTTTTGGAGCGTCTTCTCCAGCCTGCCCCAGCCCCTCATGGCCGTGCCCGCCTACCT
CTTCGTGGAAACCTTCCAACCCTTCCTGCCGGTGGGGCTTGGCCTCGCCGCCGGGGCCATGATCTGGATGGCCGCGGCCG
AGCTCCTCCCCGACGCCCTGAAGGAGGCCGAGGCCGAGGGGGTGGCCACGGTCCTCACCCTCTCCGTGGCCCTGATGGTG
GCCTTCCAGATCCTGATCGGGGGCTAA

Upstream 100 bases:

>100_bases
CCACGACCTCCTCCTGGACCGGGACCGGGAGGAGGTGGCCCGGGCGGTGCGCGACTGGCTTCTTGCAAGTGATAACTACT
TGCAATAAAATGGGCCCGGT

Downstream 100 bases:

>100_bases
GCGCCCGCGGTGGGGTCCTTAGAGCCAGACCCAGGGGAGGGGGGCCTCGAGGCGGAGGGCCTCCAGGCTCGGCCGAACCC
TATAGGCCTCCAGGACCACC

Product: divalent heavy-metal cation transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MEGLPITPWTVFLYAFLTAVATGLGALPFLFTRGITRRHLGLANAAAAGLMVAASFGLIYEGVNYSLGRTLVGVGLGLLF
ILLAHRYLEGREVNLGDLKGLDARKALMMVGIMTLHSFAEGVGVGVAFGGGEALGVFISLAIAVHNIPEGLAISLVLVPR
GVSVLGAAFWSVFSSLPQPLMAVPAYLFVETFQPFLPVGLGLAAGAMIWMAAAELLPDALKEAEAEGVATVLTLSVALMV
AFQILIGG

Sequences:

>Translated_248_residues
MEGLPITPWTVFLYAFLTAVATGLGALPFLFTRGITRRHLGLANAAAAGLMVAASFGLIYEGVNYSLGRTLVGVGLGLLF
ILLAHRYLEGREVNLGDLKGLDARKALMMVGIMTLHSFAEGVGVGVAFGGGEALGVFISLAIAVHNIPEGLAISLVLVPR
GVSVLGAAFWSVFSSLPQPLMAVPAYLFVETFQPFLPVGLGLAAGAMIWMAAAELLPDALKEAEAEGVATVLTLSVALMV
AFQILIGG
>Mature_248_residues
MEGLPITPWTVFLYAFLTAVATGLGALPFLFTRGITRRHLGLANAAAAGLMVAASFGLIYEGVNYSLGRTLVGVGLGLLF
ILLAHRYLEGREVNLGDLKGLDARKALMMVGIMTLHSFAEGVGVGVAFGGGEALGVFISLAIAVHNIPEGLAISLVLVPR
GVSVLGAAFWSVFSSLPQPLMAVPAYLFVETFQPFLPVGLGLAAGAMIWMAAAELLPDALKEAEAEGVATVLTLSVALMV
AFQILIGG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577418, Length=133, Percent_Identity=33.8345864661654, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI229577422, Length=133, Percent_Identity=33.8345864661654, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17507805, Length=155, Percent_Identity=32.9032258064516, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24652846, Length=137, Percent_Identity=35.036496350365, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 25724; Mature: 25724

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGLPITPWTVFLYAFLTAVATGLGALPFLFTRGITRRHLGLANAAAAGLMVAASFGLIY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHH
EGVNYSLGRTLVGVGLGLLFILLAHRYLEGREVNLGDLKGLDARKALMMVGIMTLHSFAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GVGVGVAFGGGEALGVFISLAIAVHNIPEGLAISLVLVPRGVSVLGAAFWSVFSSLPQPL
HHCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCHHH
MAVPAYLFVETFQPFLPVGLGLAAGAMIWMAAAELLPDALKEAEAEGVATVLTLSVALMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
AFQILIGG
HHHHHHCC
>Mature Secondary Structure
MEGLPITPWTVFLYAFLTAVATGLGALPFLFTRGITRRHLGLANAAAAGLMVAASFGLIY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHH
EGVNYSLGRTLVGVGLGLLFILLAHRYLEGREVNLGDLKGLDARKALMMVGIMTLHSFAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GVGVGVAFGGGEALGVFISLAIAVHNIPEGLAISLVLVPRGVSVLGAAFWSVFSSLPQPL
HHCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCHHH
MAVPAYLFVETFQPFLPVGLGLAAGAMIWMAAAELLPDALKEAEAEGVATVLTLSVALMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
AFQILIGG
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]