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The map label for this gene is malF [H]

Identifier: 55981620

GI number: 55981620

Start: 1565794

End: 1567122

Strand: Reverse

Name: malF [H]

Synonym: TTHA1651

Alternate gene names: 55981620

Gene position: 1567122-1565794 (Counterclockwise)

Preceding gene: 55981621

Following gene: 55981619

Centisome position: 84.72

GC content: 67.04

Gene sequence:

>1329_bases
ATGAAGCACCCTCCCGGACTCAAAGGCTTCCTCCTGGCCATGGGGCTTCTTCTGGGCCTCCTCCTCGTGGCCACGGGGCT
AGGGCTCGCCGCTTACCTCGCCCTTTCCGCCCGCCTGGATCTTCCCGGGTGGTCCGTCCTCGTCTTCGCCCTCCTCGTCC
TCGTCCCCGGGGCGGTGGCGGTGGGGCGGCTCTTCCCCTGGCTCACCGACTGGTACTACTTCCTCCCCGCCCTAGCCTTC
CTCCTCGTCTTCACCCTGTACCCCATCGGCCTCACGGTCTACCTGGCCTTCACCGACTACTCGGGGAAGCGGAACGGCTT
CCCCGACCGCTCCACCGAGACCCGGGTGGTGGCCCATGAGGGGGCGCGGCTCGTCCTCGAGGCCGAGGCCCAAGAGGCCC
TCCGCTGCGACCCTTGCGTGGGGGAGGTCGTGGAGGCCTACGCCGAAGGGCAGAGGGCCCGGGCCCGGATCCAGGCCGTG
GAAGGGGCCACCCTCCTCCTGGACCGGGCTTTGCCCTTCACGCCCGCGTACGTGGCCCGGGTCAACGCCTTCCACTTCGT
GGGGTTCAAGAACTTCGCCTTCATCCTCTCCCAGGCCAACCAGGCCCTCTTTCCCGTCTTCCTCTGGAACCTCGTCTTCG
CCTTGGCCACGGTGGTCCTGAACGGCCTCGTGGGGCTCGTCCTCGGGCTTGTGCTCAACAACCGGGCCCTGAAGCTCCGC
AACCTCTACCGCACCCTCCTCATCGTCTCCTGGGCCCTGCCCGGGGTCATCACCGTCCAGGTCTGGGTGGCCCTCCTCAA
CTACAACTTCGGGGCCATCAACCGCCTTCTCGGGGTCCTGGGCATCTACCCCATCCCCTGGCTCAACGACCCCGACTGGG
CCAAGGTGGCCGTCCTCCTCGTCAACCTCTGGCTCGGCTTTCCCTACATGATGACGGCCACCTTAGGGGCCCTTTCCACC
ATCCCCGACGAGCTCTACGAGGCGGCCAAGGTGGACGGGGCCACCCCATGGCAGGCCCTCTTCCGCATCACCCTTCCTCT
CCTGGAGAAGCCCATGCTGCCTATTCTCCTCTCCGCCTTCGCCTTCAACTTCAACAACTTCTACCTCATCTACCTCCTCA
CCGGGGGCGGCCCGGCCCAAGAGGGCAGGCTCGCCACGGCCCAGGCCACGGACATCCTCATCTCCTGGGCCTACAAGACG
GCCTTCAGCGCCGAGGGGCAGTCGGCCTACGGCCTGGGGGCGGCGATTAGCCTCCTCATCTTCGCCATCACCGTGGCCAT
AAGCCTGGTGAACTTCCGGGTGACCGGGGCGCTTCGGGAGGTGAGGTAG

Upstream 100 bases:

>100_bases
AGGACATGGTGGCCGAGATCAAGAAGGCCATCGGCAGGTAACCCCTATGGACGCTCCCCACGGGACCTCCCGCTTCCCGT
GGGGGGCGTATCTTTAGACC

Downstream 100 bases:

>100_bases
ATGCGCAAGCTCGTGGCCTTCCTCCTCACGGGCCTCGCCCTCTACGGGGCCTACTGGTTCGCGGCGAACCGCCTCTTTGA
CGAGGGGTCCTACCGCAAGC

Product: maltose ABC transporter permease

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MKHPPGLKGFLLAMGLLLGLLLVATGLGLAAYLALSARLDLPGWSVLVFALLVLVPGAVAVGRLFPWLTDWYYFLPALAF
LLVFTLYPIGLTVYLAFTDYSGKRNGFPDRSTETRVVAHEGARLVLEAEAQEALRCDPCVGEVVEAYAEGQRARARIQAV
EGATLLLDRALPFTPAYVARVNAFHFVGFKNFAFILSQANQALFPVFLWNLVFALATVVLNGLVGLVLGLVLNNRALKLR
NLYRTLLIVSWALPGVITVQVWVALLNYNFGAINRLLGVLGIYPIPWLNDPDWAKVAVLLVNLWLGFPYMMTATLGALST
IPDELYEAAKVDGATPWQALFRITLPLLEKPMLPILLSAFAFNFNNFYLIYLLTGGGPAQEGRLATAQATDILISWAYKT
AFSAEGQSAYGLGAAISLLIFAITVAISLVNFRVTGALREVR

Sequences:

>Translated_442_residues
MKHPPGLKGFLLAMGLLLGLLLVATGLGLAAYLALSARLDLPGWSVLVFALLVLVPGAVAVGRLFPWLTDWYYFLPALAF
LLVFTLYPIGLTVYLAFTDYSGKRNGFPDRSTETRVVAHEGARLVLEAEAQEALRCDPCVGEVVEAYAEGQRARARIQAV
EGATLLLDRALPFTPAYVARVNAFHFVGFKNFAFILSQANQALFPVFLWNLVFALATVVLNGLVGLVLGLVLNNRALKLR
NLYRTLLIVSWALPGVITVQVWVALLNYNFGAINRLLGVLGIYPIPWLNDPDWAKVAVLLVNLWLGFPYMMTATLGALST
IPDELYEAAKVDGATPWQALFRITLPLLEKPMLPILLSAFAFNFNNFYLIYLLTGGGPAQEGRLATAQATDILISWAYKT
AFSAEGQSAYGLGAAISLLIFAITVAISLVNFRVTGALREVR
>Mature_442_residues
MKHPPGLKGFLLAMGLLLGLLLVATGLGLAAYLALSARLDLPGWSVLVFALLVLVPGAVAVGRLFPWLTDWYYFLPALAF
LLVFTLYPIGLTVYLAFTDYSGKRNGFPDRSTETRVVAHEGARLVLEAEAQEALRCDPCVGEVVEAYAEGQRARARIQAV
EGATLLLDRALPFTPAYVARVNAFHFVGFKNFAFILSQANQALFPVFLWNLVFALATVVLNGLVGLVLGLVLNNRALKLR
NLYRTLLIVSWALPGVITVQVWVALLNYNFGAINRLLGVLGIYPIPWLNDPDWAKVAVLLVNLWLGFPYMMTATLGALST
IPDELYEAAKVDGATPWQALFRITLPLLEKPMLPILLSAFAFNFNNFYLIYLLTGGGPAQEGRLATAQATDILISWAYKT
AFSAEGQSAYGLGAAISLLIFAITVAISLVNFRVTGALREVR

Specific function: Part of the binding-protein-dependent transport system for maltose; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Periplasmic side. Note=A substantial portion of it protrudes into the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790465, Length=252, Percent_Identity=43.6507936507937, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1787570, Length=249, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789861, Length=251, Percent_Identity=26.2948207171315, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 48223; Mature: 48223

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHPPGLKGFLLAMGLLLGLLLVATGLGLAAYLALSARLDLPGWSVLVFALLVLVPGAVA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHH
VGRLFPWLTDWYYFLPALAFLLVFTLYPIGLTVYLAFTDYSGKRNGFPDRSTETRVVAHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCEEEEEC
GARLVLEAEAQEALRCDPCVGEVVEAYAEGQRARARIQAVEGATLLLDRALPFTPAYVAR
CCEEEEECCHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHCCCCCCHHHHHH
VNAFHFVGFKNFAFILSQANQALFPVFLWNLVFALATVVLNGLVGLVLGLVLNNRALKLR
HHHHEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
NLYRTLLIVSWALPGVITVQVWVALLNYNFGAINRLLGVLGIYPIPWLNDPDWAKVAVLL
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
VNLWLGFPYMMTATLGALSTIPDELYEAAKVDGATPWQALFRITLPLLEKPMLPILLSAF
HHHHHCCHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
AFNFNNFYLIYLLTGGGPAQEGRLATAQATDILISWAYKTAFSAEGQSAYGLGAAISLLI
HHCCCCEEEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
FAITVAISLVNFRVTGALREVR
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKHPPGLKGFLLAMGLLLGLLLVATGLGLAAYLALSARLDLPGWSVLVFALLVLVPGAVA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHH
VGRLFPWLTDWYYFLPALAFLLVFTLYPIGLTVYLAFTDYSGKRNGFPDRSTETRVVAHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCEEEEEC
GARLVLEAEAQEALRCDPCVGEVVEAYAEGQRARARIQAVEGATLLLDRALPFTPAYVAR
CCEEEEECCHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHCCCCCCHHHHHH
VNAFHFVGFKNFAFILSQANQALFPVFLWNLVFALATVVLNGLVGLVLGLVLNNRALKLR
HHHHEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
NLYRTLLIVSWALPGVITVQVWVALLNYNFGAINRLLGVLGIYPIPWLNDPDWAKVAVLL
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
VNLWLGFPYMMTATLGALSTIPDELYEAAKVDGATPWQALFRITLPLLEKPMLPILLSAF
HHHHHCCHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
AFNFNNFYLIYLLTGGGPAQEGRLATAQATDILISWAYKTAFSAEGQSAYGLGAAISLLI
HHCCCCEEEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
FAITVAISLVNFRVTGALREVR
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2674653 [H]