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The map label for this gene is prpC [H]

Identifier: 55981564

GI number: 55981564

Start: 1517900

End: 1518664

Strand: Reverse

Name: prpC [H]

Synonym: TTHA1595

Alternate gene names: 55981564

Gene position: 1518664-1517900 (Counterclockwise)

Preceding gene: 55981567

Following gene: 55981563

Centisome position: 82.1

GC content: 73.73

Gene sequence:

>765_bases
ATGGAGCCGATGCGCATCGGTCCCCGGCTGAGCGTGGCCGCCGTTTCCCACGTGGGCCGCCGCCAGAACAACGAGGACTT
CCACCGGGTCCTCCCCCTGGAGACGCCCGCGGGGCTTTTGCTCCTCCTCGCGGTGGCCGACGGGATGGGGGGCCTCGAGG
CCGGGGAGTGGGCGAGCAAGCTCGCCATTGAGGCCCTCTCCGAGGCGGCCCGGGGCTACGCGGAGCACCTCCAGAGCGGC
CGCCCCGCCGTGGGCCTCGCCCGGGTCATGGAAAAGGGTTTCCTCCTGGCCCGGCGCCGGGTGGAGCGGGAGGCGGAGCG
GCCCGGGCGCCGGGGGATGGGCACCACCCTCACCGCCTTCCTCTACGCCGACTGGCTCAAGGAGGGGGTGGTGGGGCACA
TCGGCGACTCCCGGGCCTACCGCTTCGGCCCCACCGGGGTTTTTCGCCTCACCGAGGACCACTCCTGGGTGGCGGAACGC
CTGAAGGAGGGGGTCCTCACCCGGACCGAGGCGGAGCGCCACCCCTACCGCAACGTCCTCACCCGGGCCCTGGGCCTTCC
CGAGGCGCGCTTTGACCTCGTGGAGGTGCGCCTCGCCCCGGGAGAGGGGGTGCTTCTCGTGACCGACGGGCTCTACGGGC
ACGTGCCCGAGGAGGAGTGGCGGCTTGGGCGGGACCTCCAGGCGAGCCTGGAGGCCATGGTGGCCGAGGCCTTGCGGCGG
GGCGGGGACGACAACGTCACCGCCGTGGCCCTGCGGGTGGAGTGA

Upstream 100 bases:

>100_bases
CTTCCCCCCTTTAGGCGTGCGGCCCTGGAGGAGGTCCTCCACCCGGTACTCGTAGAGGTCCACCAGGTCGTCCAGGTGGT
CCACGCCTCCATCCTATACA

Downstream 100 bases:

>100_bases
TGGCCCTGCTCCTCGCCGCCCTCCTCGTCCTCCTCACGGCCCTCCTGGCCGTCCGCCTCCCGGCCTGGGCCTCGGCCCTC
CTCCTCGGCCTTCTCGCCGG

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MEPMRIGPRLSVAAVSHVGRRQNNEDFHRVLPLETPAGLLLLLAVADGMGGLEAGEWASKLAIEALSEAARGYAEHLQSG
RPAVGLARVMEKGFLLARRRVEREAERPGRRGMGTTLTAFLYADWLKEGVVGHIGDSRAYRFGPTGVFRLTEDHSWVAER
LKEGVLTRTEAERHPYRNVLTRALGLPEARFDLVEVRLAPGEGVLLVTDGLYGHVPEEEWRLGRDLQASLEAMVAEALRR
GGDDNVTAVALRVE

Sequences:

>Translated_254_residues
MEPMRIGPRLSVAAVSHVGRRQNNEDFHRVLPLETPAGLLLLLAVADGMGGLEAGEWASKLAIEALSEAARGYAEHLQSG
RPAVGLARVMEKGFLLARRRVEREAERPGRRGMGTTLTAFLYADWLKEGVVGHIGDSRAYRFGPTGVFRLTEDHSWVAER
LKEGVLTRTEAERHPYRNVLTRALGLPEARFDLVEVRLAPGEGVLLVTDGLYGHVPEEEWRLGRDLQASLEAMVAEALRR
GGDDNVTAVALRVE
>Mature_254_residues
MEPMRIGPRLSVAAVSHVGRRQNNEDFHRVLPLETPAGLLLLLAVADGMGGLEAGEWASKLAIEALSEAARGYAEHLQSG
RPAVGLARVMEKGFLLARRRVEREAERPGRRGMGTTLTAFLYADWLKEGVVGHIGDSRAYRFGPTGVFRLTEDHSWVAER
LKEGVLTRTEAERHPYRNVLTRALGLPEARFDLVEVRLAPGEGVLLVTDGLYGHVPEEEWRLGRDLQASLEAMVAEALRR
GGDDNVTAVALRVE

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 27959; Mature: 27959

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPMRIGPRLSVAAVSHVGRRQNNEDFHRVLPLETPAGLLLLLAVADGMGGLEAGEWASK
CCCCCCCCCHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
LAIEALSEAARGYAEHLQSGRPAVGLARVMEKGFLLARRRVEREAERPGRRGMGTTLTAF
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
LYADWLKEGVVGHIGDSRAYRFGPTGVFRLTEDHSWVAERLKEGVLTRTEAERHPYRNVL
HHHHHHHCCCEECCCCCCCEEECCCEEEEECCCHHHHHHHHHHCCHHHHHHHCCHHHHHH
TRALGLPEARFDLVEVRLAPGEGVLLVTDGLYGHVPEEEWRLGRDLQASLEAMVAEALRR
HHHHCCCHHHEEEEEEEECCCCCEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHC
GGDDNVTAVALRVE
CCCCCEEEEEEEEC
>Mature Secondary Structure
MEPMRIGPRLSVAAVSHVGRRQNNEDFHRVLPLETPAGLLLLLAVADGMGGLEAGEWASK
CCCCCCCCCHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
LAIEALSEAARGYAEHLQSGRPAVGLARVMEKGFLLARRRVEREAERPGRRGMGTTLTAF
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
LYADWLKEGVVGHIGDSRAYRFGPTGVFRLTEDHSWVAERLKEGVLTRTEAERHPYRNVL
HHHHHHHCCCEECCCCCCCEEECCCEEEEECCCHHHHHHHHHHCCHHHHHHHCCHHHHHH
TRALGLPEARFDLVEVRLAPGEGVLLVTDGLYGHVPEEEWRLGRDLQASLEAMVAEALRR
HHHHCCCHHHEEEEEEEECCCCCEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHC
GGDDNVTAVALRVE
CCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]