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The map label for this gene is rpfG [H]

Identifier: 55981345

GI number: 55981345

Start: 1312180

End: 1313586

Strand: Direct

Name: rpfG [H]

Synonym: TTHA1376

Alternate gene names: 55981345

Gene position: 1312180-1313586 (Clockwise)

Preceding gene: 55981343

Following gene: 55981346

Centisome position: 70.94

GC content: 64.25

Gene sequence:

>1407_bases
ATGGCCTTTAAACGCTTGGAGCTTCCCCCGCCGCGGGTGCTCCTTTTGGTCCTTTCGGCCTTCCTGGGCTTCCTGGCCCT
GGAGGGTTTCTTGCTTTGGGCCTACAGAAGTGCGCCCCTCCGCTTGAGCCTCCTGGACCTGCTCTTCTGGGGGGCGCTTA
TGCTTTGGAGCGTATCCGTTCGCGTCCCCCTTCCCTTAAGCGCCAGCATGAGCCAGTTTTTTATCTTTGCCCTGGCTTTG
GTAGCGTTAACATCCCCATGGGTACCACCCCTTCTCAGCTTTTTGCTTCAGTGGCGCCGAAAAGTCTGGTACAAGGAGCT
CTTTAATAGCTCCCAGAATGCTTTGGCCACCGCCCTGGCGGCCCTGGTTTGGCAGTTCTTTCAGCAGAACCCCCTATATC
TCGGCTCGTGGGACCTTTCCGCCGGGGTAGGCATCGCCGCGGCCTCCCTGGCCTTCTTCCTAGCCAACACCACCCTGGTA
ACCACCGCCATCCACCTAGCCAACGACGTTCCCTGGCATGAAGCGTGGCGGAAAAACTTCAGCTGGCTTGCCCTCAGCTA
CCTCCTCCTCTCCCCCATCGCCCTCCTCCTCGCCCGGGCGTACGAAACGCCCCTCCTGGGGAACTGGGGTGGGTGGACGG
TGCTCTTCTTCCTCATCCCCCTCTACTACAGCCGCTTCTACTGGGACGAGAAGGTGCGCCTGGAGCAGGCCTTTGACACC
ACCTTGGAGCTTCTGATGAACGCCCTCGAGGCCAAGGACCCCATGACCCGCCTCCACTCCGAACGGGTGGCGGACATCGC
CCGCGACCTGGCCCGCAAGGTCAAGGACGGGAACGAGGCCTACGCCCAGGCCATCTACCGGGCGGCCAGGCTCCACGACA
TCGGCAAGATCGCCATCCCCGAGGCCGTCCTCCTCAAGCCCGGATCCCTCACCCCCGAGGAGTTCGCCCTCATCCAAAGC
CACACCACCAAGGGGGCCGAGCTCCTCTCTCCGGCGCGGAAGGTGGCCTTTGACCAGCTCGTCTACAACGTCATCCTGCA
CCACCACGAGCGCTGGGACGGGCGGGGCTACCCCAAGCGGCTCGCCGGGCACGAGATCCCCGAGGAGGCCCGCATCGTGG
GCCTGGCGGACGCTTACGAGGCCATGACCGCGGGGCGGCCCTACCGCAAGGCCAAGACCCCCGAGGAAGCGCTGAGGGAG
GTCCAGGAGCTTTCCGGCCACCAGTTTGACCCCCGGTTGGTGGAAGCCTTCACCGAGCTTTGGGCGCAGAACCCCATCTG
GCGCGACCGCCACGCCTATCTGGCGGCAAAGGAGGGATCGGTATCACGCTCTACCTTCTCGCAGCCCTCTTCGGCCTCGG
CCTCGCCCTCGCCCTCGGAGCCCGGCCCAAGGACCTCGGAGGAATAG

Upstream 100 bases:

>100_bases
CGGCTGGAGCAAGTGCTCGCTGGGAATAGGAAGGAGGCCAGCTAAGCTGGCCTCCTTTTTCTTGCACCGGGGAAGGGGGA
TTTGCTACACTCAGGCCACC

Downstream 100 bases:

>100_bases
AGCTCAGGGCGGCCTGGGCCTTCTTTCTGGCCGCCCTCTTGGAAGGGGGGTTGGCCTACGGGACCTACCGGGGCCTCTTC
GCCCCGGAGGTGGCCGGCCC

Product: HD domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MAFKRLELPPPRVLLLVLSAFLGFLALEGFLLWAYRSAPLRLSLLDLLFWGALMLWSVSVRVPLPLSASMSQFFIFALAL
VALTSPWVPPLLSFLLQWRRKVWYKELFNSSQNALATALAALVWQFFQQNPLYLGSWDLSAGVGIAAASLAFFLANTTLV
TTAIHLANDVPWHEAWRKNFSWLALSYLLLSPIALLLARAYETPLLGNWGGWTVLFFLIPLYYSRFYWDEKVRLEQAFDT
TLELLMNALEAKDPMTRLHSERVADIARDLARKVKDGNEAYAQAIYRAARLHDIGKIAIPEAVLLKPGSLTPEEFALIQS
HTTKGAELLSPARKVAFDQLVYNVILHHHERWDGRGYPKRLAGHEIPEEARIVGLADAYEAMTAGRPYRKAKTPEEALRE
VQELSGHQFDPRLVEAFTELWAQNPIWRDRHAYLAAKEGSVSRSTFSQPSSASASPSPSEPGPRTSEE

Sequences:

>Translated_468_residues
MAFKRLELPPPRVLLLVLSAFLGFLALEGFLLWAYRSAPLRLSLLDLLFWGALMLWSVSVRVPLPLSASMSQFFIFALAL
VALTSPWVPPLLSFLLQWRRKVWYKELFNSSQNALATALAALVWQFFQQNPLYLGSWDLSAGVGIAAASLAFFLANTTLV
TTAIHLANDVPWHEAWRKNFSWLALSYLLLSPIALLLARAYETPLLGNWGGWTVLFFLIPLYYSRFYWDEKVRLEQAFDT
TLELLMNALEAKDPMTRLHSERVADIARDLARKVKDGNEAYAQAIYRAARLHDIGKIAIPEAVLLKPGSLTPEEFALIQS
HTTKGAELLSPARKVAFDQLVYNVILHHHERWDGRGYPKRLAGHEIPEEARIVGLADAYEAMTAGRPYRKAKTPEEALRE
VQELSGHQFDPRLVEAFTELWAQNPIWRDRHAYLAAKEGSVSRSTFSQPSSASASPSPSEPGPRTSEE
>Mature_467_residues
AFKRLELPPPRVLLLVLSAFLGFLALEGFLLWAYRSAPLRLSLLDLLFWGALMLWSVSVRVPLPLSASMSQFFIFALALV
ALTSPWVPPLLSFLLQWRRKVWYKELFNSSQNALATALAALVWQFFQQNPLYLGSWDLSAGVGIAAASLAFFLANTTLVT
TAIHLANDVPWHEAWRKNFSWLALSYLLLSPIALLLARAYETPLLGNWGGWTVLFFLIPLYYSRFYWDEKVRLEQAFDTT
LELLMNALEAKDPMTRLHSERVADIARDLARKVKDGNEAYAQAIYRAARLHDIGKIAIPEAVLLKPGSLTPEEFALIQSH
TTKGAELLSPARKVAFDQLVYNVILHHHERWDGRGYPKRLAGHEIPEEARIVGLADAYEAMTAGRPYRKAKTPEEALREV
QELSGHQFDPRLVEAFTELWAQNPIWRDRHAYLAAKEGSVSRSTFSQPSSASASPSPSEPGPRTSEE

Specific function: Positively regulates the synthesis of extracellular enzymes and extracellular polysaccharides. The cell-cell signaling system encoded by rpf genes is required for full virulence and is implicated in regulation of the formation and dispersal of biofilms [H

COG id: COG2206

COG function: function code T; HD-GYP domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR003607
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 52753; Mature: 52622

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFKRLELPPPRVLLLVLSAFLGFLALEGFLLWAYRSAPLRLSLLDLLFWGALMLWSVSV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
RVPLPLSASMSQFFIFALALVALTSPWVPPLLSFLLQWRRKVWYKELFNSSQNALATALA
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ALVWQFFQQNPLYLGSWDLSAGVGIAAASLAFFLANTTLVTTAIHLANDVPWHEAWRKNF
HHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCH
SWLALSYLLLSPIALLLARAYETPLLGNWGGWTVLFFLIPLYYSRFYWDEKVRLEQAFDT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
TLELLMNALEAKDPMTRLHSERVADIARDLARKVKDGNEAYAQAIYRAARLHDIGKIAIP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
EAVLLKPGSLTPEEFALIQSHTTKGAELLSPARKVAFDQLVYNVILHHHERWDGRGYPKR
CHHEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
LAGHEIPEEARIVGLADAYEAMTAGRPYRKAKTPEEALREVQELSGHQFDPRLVEAFTEL
HCCCCCCCHHHEEEHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
WAQNPIWRDRHAYLAAKEGSVSRSTFSQPSSASASPSPSEPGPRTSEE
HHCCCCCCCCHHEEEECCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AFKRLELPPPRVLLLVLSAFLGFLALEGFLLWAYRSAPLRLSLLDLLFWGALMLWSVSV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
RVPLPLSASMSQFFIFALALVALTSPWVPPLLSFLLQWRRKVWYKELFNSSQNALATALA
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ALVWQFFQQNPLYLGSWDLSAGVGIAAASLAFFLANTTLVTTAIHLANDVPWHEAWRKNF
HHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCH
SWLALSYLLLSPIALLLARAYETPLLGNWGGWTVLFFLIPLYYSRFYWDEKVRLEQAFDT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
TLELLMNALEAKDPMTRLHSERVADIARDLARKVKDGNEAYAQAIYRAARLHDIGKIAIP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
EAVLLKPGSLTPEEFALIQSHTTKGAELLSPARKVAFDQLVYNVILHHHERWDGRGYPKR
CHHEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
LAGHEIPEEARIVGLADAYEAMTAGRPYRKAKTPEEALREVQELSGHQFDPRLVEAFTEL
HCCCCCCCHHHEEEHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
WAQNPIWRDRHAYLAAKEGSVSRSTFSQPSSASASPSPSEPGPRTSEE
HHCCCCCCCCHHEEEECCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11123673 [H]