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The map label for this gene is hupA [C]

Identifier: 55981318

GI number: 55981318

Start: 1289898

End: 1290191

Strand: Direct

Name: hupA [C]

Synonym: TTHA1349

Alternate gene names: 55981318

Gene position: 1289898-1290191 (Clockwise)

Preceding gene: 55981317

Following gene: 55981322

Centisome position: 69.73

GC content: 62.93

Gene sequence:

>294_bases
ATGGCTGCGAAGAAGACGGTGACCAAAGCGGATCTGGTGGACCAGGTGGCCCAGGCCACCGGGCTCAAGAAGAAGGACGT
GAAGGCCATGGTGGACGCCCTGCTGGCCAAGGTGGAGGAGGCCTTGGCCAACGGGAGCAAGGTCCAGCTCACGGGCTTCG
GCACCTTTGAGGTGCGCAAGCGCAAGGCCCGCACCGGGGTGAAGCCGGGCACCAAGGAGAAGATCAAGATCCCCGCCACC
CAGTATCCCGCCTTCAAGCCCGGCAAGGCCCTGAAGGATAAGGTCAAGAAGTAA

Upstream 100 bases:

>100_bases
CATAGCTGCGGATTTTTATAGAAAAGAGACCAGACCTTGAGAAGTACCCTTAAGCGTGATATATTCCGCCCGGAAGGGCA
AAGAAGCGAGGAGGTGAGAG

Downstream 100 bases:

>100_bases
GCGGCCCTTCCGCCGGGGGGGGCGCTAGCCCCCCCGGTTGCCCTTTTCCATCTCCGCCTTGAGGGCGGCGAGGGGCTCCT
GCCAGTCCTCCCCCAGGGTG

Product: DNA-binding protein HU

Products: NA

Alternate protein names: DNA-binding protein II; TL29 [H]

Number of amino acids: Translated: 97; Mature: 96

Protein sequence:

>97_residues
MAAKKTVTKADLVDQVAQATGLKKKDVKAMVDALLAKVEEALANGSKVQLTGFGTFEVRKRKARTGVKPGTKEKIKIPAT
QYPAFKPGKALKDKVKK

Sequences:

>Translated_97_residues
MAAKKTVTKADLVDQVAQATGLKKKDVKAMVDALLAKVEEALANGSKVQLTGFGTFEVRKRKARTGVKPGTKEKIKIPAT
QYPAFKPGKALKDKVKK
>Mature_96_residues
AAKKTVTKADLVDQVAQATGLKKKDVKAMVDALLAKVEEALANGSKVQLTGFGTFEVRKRKARTGVKPGTKEKIKIPATQ
YPAFKPGKALKDKVKK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=47.7777777777778, Blast_Score=81, Evalue=1e-17,
Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=43.3333333333333, Blast_Score=78, Evalue=1e-16,
Organism=Escherichia coli, GI1788005, Length=91, Percent_Identity=37.3626373626374, Blast_Score=74, Evalue=2e-15,
Organism=Escherichia coli, GI1787141, Length=89, Percent_Identity=34.8314606741573, Blast_Score=67, Evalue=2e-13,

Paralogues:

None

Copy number: 1380 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 10453; Mature: 10321

Theoretical pI: Translated: 11.01; Mature: 11.01

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAKKTVTKADLVDQVAQATGLKKKDVKAMVDALLAKVEEALANGSKVQLTGFGTFEVRK
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHH
RKARTGVKPGTKEKIKIPATQYPAFKPGKALKDKVKK
HHHHCCCCCCCCCEEECCCCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
AAKKTVTKADLVDQVAQATGLKKKDVKAMVDALLAKVEEALANGSKVQLTGFGTFEVRK
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHH
RKARTGVKPGTKEKIKIPATQYPAFKPGKALKDKVKK
HHHHCCCCCCCCCEEECCCCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2226865 [H]