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The map label for this gene is yprA [H]

Identifier: 55981226

GI number: 55981226

Start: 1194627

End: 1196813

Strand: Direct

Name: yprA [H]

Synonym: TTHA1257

Alternate gene names: 55981226

Gene position: 1194627-1196813 (Clockwise)

Preceding gene: 55981224

Following gene: 55981227

Centisome position: 64.58

GC content: 73.39

Gene sequence:

>2187_bases
GTGCTGCCCGAGCCGCTTCGGGGCTATTCCAGCTACCGGGAGTGGCTGGAGGCGGAGGAGGAGTTCAAGGGGCGGGTGGT
CTTCGCCCGCCTCCTCCCCAAGGCCCCCCCGAGGCCCGCGCCCTACGAGGGGGCCTTCGCCGGGGTCCTCCGGGCCCTCG
GCCTCACGCCCTACCTCCACCAGCAAAGGGCCCTAAAGCGGGTGGAGGCGGGGGCCAACGTGGTCCTCGCCTACCCCACC
GCCGCCGGGAAAAGCCTGGTCTACCAGGCCCCGGTGCTCCAGGCCGCCCTCGAGGGGGCCACGAGCCTCCTCCTCTTCCC
CACCAAGGCCCTGGCCCACGACCAGCTCCGCCGCCTCCGGGCCATGGCCCAGGTCCTGGGGGTGGAGGGCGTCTTCCCCT
ACGACGGGGACACCCCCTCCGCCACGCGGCGGCAGGCCCGGGAGCGGGGCCTCGTCCTCCTCTCCAACCCCGACATGCTC
CACTACGGCCTCCTGCCCCGCCACCCGGACTGGGCCCCCTTCCTCGCCCGGCTCCGCTACGTGGTGCTGGACGAGCTCCA
CGCCTACCGGGGGGTGTTCGGCACCCACGTGGCCCTGATCCTGAGGCGCCTCCTCCGCCTGGCCCGGCACTACGGGGCCT
CCCCCCAGGTCCTCGCCGCAAGCGCCACCATCGCCAACGCCCGGGAGCACGCGGAAGCCCTCACGGGCCTCCCCTTTGAG
GAGCTCAAAGCCCAGGTGGCCCGGACGGAGCGGGAGCTCCTCGTCCTCCTCCCCAAGCCCTTGGACCGGAGGGGGGAGCG
CAGGCGGAGCCCCCTCCTCGAGGCGGCCTACCTGGCCCGGCGCCTGGCGGAAGCGGGGCTCAAGGGGCTCGTCTTCGCCG
GGGCCCGCAAGTCGGCGGAGCTCATCGCCCGCTACGCCGCCCACCCCCTGGTGCGGCCTTACCGGGCGGGGTACACGGCC
CGGGAGCGCCGCCGCCTGGAGGCGGACCTCAAGGAGGGGCGGGTGCGGGTCCTGGTCTCCACCAGCGCCCTGGAGCTCGG
GGTGGACATCGGGGAGCTGGACGCCGTGGTCCTGGTGGGCTACCCGGGCTCCACCGCCGCCTTCTGGCAGCGGGCGGGCC
GGGCGGGCCGGGGGGAGCGGCGGGCCCTCTTGGTCTACATCCCCCGGGAGGACCCCATGGACGAGTACTTCCTCCACCGC
CCCGCCCTCCTCCTGGAAAGCCCCCCCGAGGAGGCGGTGGCGGACCCGCAAAACCCCGTCCTCTGCCCCCTGCACCTCCA
CGCGGCGGCCCGGGAAAAGCCCCTGTTGGCGGAGGAGCTCCTCTGCCCCGAGGCCCGGGCCACCTTAAAGGAGCGGAACG
GGCGGTTCTTCACCCCGAAGCGCAACCCCCACCGGGAGATCACCCTGAGGGGCCTCGGCGCCACCTTCACCCTGCGGGGC
CCGGACGGGGAGGTGTTGGGCTACCTGGACGAGCGGCAGGCCTACTGGGAGGCCCACCCCGGGGCCATCTACCTGCACCA
GGGGGAGAGCTACCTGGTGCGGAACGTGGACCTGGCCCGGCGCGAGGTCTGGCTCCTTCCCGCCCTGGAGGACTACTACA
CCGAGCCCCGGGCGGAGACGGACCTCGAGGTCCTCTCCGGGGAGGAGGTGGGCCCCGGGGTGTGGGTGGGCCGGGTGGTC
CTGAGGGAAAGGGTGGTGGGGTACGTGAAGAAGCGCTTCTACACGGGGAGCGTCCTGGAGGAGGTGCCCCTGGAGATGCC
GGAGGTCTCCTTTCCCACGGAGGCGCTCTGGTTCCACCCCCCCGAGGCCGTCCCCGCCTTCCAGATCCCCGGCGGGATCC
ACGCCCTGGAGCACGCCATGATCGGCCTCTTGCCCCTCTTCGTCCTGGCGGAGCGGCAGGACGTGGGCGGGATCTCCTAC
CCCTTCTACCCCAGGCCCCTTCCCTCCCCGGGCGGGCCCACGGTCTTCATCTACGACGGCTACCCCGGGGGGGTGGGGTA
CGCCCGCCGGGCGGCCCGGCGCTTCCCCGAGTGGCTCAAGGCCACCCTGGACCTCCTCCGCTCCTGCCCCTGCGAGGAGG
GCTGCCCCCGGTGCGTCCTCTCCCCCAAGTGCGGCAACGGCAACCAGTACCTGGACAAAAAGGCGGCCCTGGCCCTCGCC
TTGGCCTTGGCCCACCCCTTAGACTGA

Upstream 100 bases:

>100_bases
CCCACGATGGCCTCCCCGAAGACGATGCCCAGGTACCGCTCTATCCGCCTTCCCTCTATCTCGTGGGTCGTGGTGAGGAT
CATGCCCCCATAATAAGGGG

Downstream 100 bases:

>100_bases
GAAGCATGAGCCCCGTGGAGGAAAGCCCGGAGGAGTTCCTGGCCCGCTTCGCCGCCCACCGGGTGGAGGTGAGGCTCTAC
CCCGAGCCCTGGGGGAGCCC

Product: helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 728; Mature: 728

Protein sequence:

>728_residues
MLPEPLRGYSSYREWLEAEEEFKGRVVFARLLPKAPPRPAPYEGAFAGVLRALGLTPYLHQQRALKRVEAGANVVLAYPT
AAGKSLVYQAPVLQAALEGATSLLLFPTKALAHDQLRRLRAMAQVLGVEGVFPYDGDTPSATRRQARERGLVLLSNPDML
HYGLLPRHPDWAPFLARLRYVVLDELHAYRGVFGTHVALILRRLLRLARHYGASPQVLAASATIANAREHAEALTGLPFE
ELKAQVARTERELLVLLPKPLDRRGERRRSPLLEAAYLARRLAEAGLKGLVFAGARKSAELIARYAAHPLVRPYRAGYTA
RERRRLEADLKEGRVRVLVSTSALELGVDIGELDAVVLVGYPGSTAAFWQRAGRAGRGERRALLVYIPREDPMDEYFLHR
PALLLESPPEEAVADPQNPVLCPLHLHAAAREKPLLAEELLCPEARATLKERNGRFFTPKRNPHREITLRGLGATFTLRG
PDGEVLGYLDERQAYWEAHPGAIYLHQGESYLVRNVDLARREVWLLPALEDYYTEPRAETDLEVLSGEEVGPGVWVGRVV
LRERVVGYVKKRFYTGSVLEEVPLEMPEVSFPTEALWFHPPEAVPAFQIPGGIHALEHAMIGLLPLFVLAERQDVGGISY
PFYPRPLPSPGGPTVFIYDGYPGGVGYARRAARRFPEWLKATLDLLRSCPCEEGCPRCVLSPKCGNGNQYLDKKAALALA
LALAHPLD

Sequences:

>Translated_728_residues
MLPEPLRGYSSYREWLEAEEEFKGRVVFARLLPKAPPRPAPYEGAFAGVLRALGLTPYLHQQRALKRVEAGANVVLAYPT
AAGKSLVYQAPVLQAALEGATSLLLFPTKALAHDQLRRLRAMAQVLGVEGVFPYDGDTPSATRRQARERGLVLLSNPDML
HYGLLPRHPDWAPFLARLRYVVLDELHAYRGVFGTHVALILRRLLRLARHYGASPQVLAASATIANAREHAEALTGLPFE
ELKAQVARTERELLVLLPKPLDRRGERRRSPLLEAAYLARRLAEAGLKGLVFAGARKSAELIARYAAHPLVRPYRAGYTA
RERRRLEADLKEGRVRVLVSTSALELGVDIGELDAVVLVGYPGSTAAFWQRAGRAGRGERRALLVYIPREDPMDEYFLHR
PALLLESPPEEAVADPQNPVLCPLHLHAAAREKPLLAEELLCPEARATLKERNGRFFTPKRNPHREITLRGLGATFTLRG
PDGEVLGYLDERQAYWEAHPGAIYLHQGESYLVRNVDLARREVWLLPALEDYYTEPRAETDLEVLSGEEVGPGVWVGRVV
LRERVVGYVKKRFYTGSVLEEVPLEMPEVSFPTEALWFHPPEAVPAFQIPGGIHALEHAMIGLLPLFVLAERQDVGGISY
PFYPRPLPSPGGPTVFIYDGYPGGVGYARRAARRFPEWLKATLDLLRSCPCEEGCPRCVLSPKCGNGNQYLDKKAALALA
LALAHPLD
>Mature_728_residues
MLPEPLRGYSSYREWLEAEEEFKGRVVFARLLPKAPPRPAPYEGAFAGVLRALGLTPYLHQQRALKRVEAGANVVLAYPT
AAGKSLVYQAPVLQAALEGATSLLLFPTKALAHDQLRRLRAMAQVLGVEGVFPYDGDTPSATRRQARERGLVLLSNPDML
HYGLLPRHPDWAPFLARLRYVVLDELHAYRGVFGTHVALILRRLLRLARHYGASPQVLAASATIANAREHAEALTGLPFE
ELKAQVARTERELLVLLPKPLDRRGERRRSPLLEAAYLARRLAEAGLKGLVFAGARKSAELIARYAAHPLVRPYRAGYTA
RERRRLEADLKEGRVRVLVSTSALELGVDIGELDAVVLVGYPGSTAAFWQRAGRAGRGERRALLVYIPREDPMDEYFLHR
PALLLESPPEEAVADPQNPVLCPLHLHAAAREKPLLAEELLCPEARATLKERNGRFFTPKRNPHREITLRGLGATFTLRG
PDGEVLGYLDERQAYWEAHPGAIYLHQGESYLVRNVDLARREVWLLPALEDYYTEPRAETDLEVLSGEEVGPGVWVGRVV
LRERVVGYVKKRFYTGSVLEEVPLEMPEVSFPTEALWFHPPEAVPAFQIPGGIHALEHAMIGLLPLFVLAERQDVGGISY
PFYPRPLPSPGGPTVFIYDGYPGGVGYARRAARRFPEWLKATLDLLRSCPCEEGCPRCVLSPKCGNGNQYLDKKAALALA
LALAHPLD

Specific function: Unknown

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320497, Length=729, Percent_Identity=28.8065843621399, Blast_Score=310, Evalue=5e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 80935; Mature: 80935

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPEPLRGYSSYREWLEAEEEFKGRVVFARLLPKAPPRPAPYEGAFAGVLRALGLTPYLH
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHH
QQRALKRVEAGANVVLAYPTAAGKSLVYQAPVLQAALEGATSLLLFPTKALAHDQLRRLR
HHHHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHH
AMAQVLGVEGVFPYDGDTPSATRRQARERGLVLLSNPDMLHYGLLPRHPDWAPFLARLRY
HHHHHHCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCEEEECCCCCCCCHHHHHHHHHH
VVLDELHAYRGVFGTHVALILRRLLRLARHYGASPQVLAASATIANAREHAEALTGLPFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCCHH
ELKAQVARTERELLVLLPKPLDRRGERRRSPLLEAAYLARRLAEAGLKGLVFAGARKSAE
HHHHHHHHCCCCEEEECCCCCCCCHHHHHCHHHHHHHHHHHHHHCCCCEEEEECCCHHHH
LIARYAAHPLVRPYRAGYTARERRRLEADLKEGRVRVLVSTSALELGVDIGELDAVVLVG
HHHHHHHCCCCCHHHCCCCHHHHHHHHHHHCCCCEEEEEEECHHHHCCCCCCCCEEEEEE
YPGSTAAFWQRAGRAGRGERRALLVYIPREDPMDEYFLHRPALLLESPPEEAVADPQNPV
CCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHCCHHEECCCCHHHHCCCCCCE
LCPLHLHAAAREKPLLAEELLCPEARATLKERNGRFFTPKRNPHREITLRGLGATFTLRG
EEEEEHHHHHCCCCCHHHHHCCCHHHHHHHHCCCCEECCCCCCCCEEEEEECCEEEEEEC
PDGEVLGYLDERQAYWEAHPGAIYLHQGESYLVRNVDLARREVWLLPALEDYYTEPRAET
CCCCEEEEHHHHHHHHCCCCCEEEEECCCCEEEECCHHHHHHEEEECCHHHHCCCCCCCC
DLEVLSGEEVGPGVWVGRVVLRERVVGYVKKRFYTGSVLEEVPLEMPEVSFPTEALWFHP
CHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCEEEECC
PEAVPAFQIPGGIHALEHAMIGLLPLFVLAERQDVGGISYPFYPRPLPSPGGPTVFIYDG
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECC
YPGGVGYARRAARRFPEWLKATLDLLRSCPCEEGCPRCVLSPKCGNGNQYLDKKAALALA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHH
LALAHPLD
HHHHCCCC
>Mature Secondary Structure
MLPEPLRGYSSYREWLEAEEEFKGRVVFARLLPKAPPRPAPYEGAFAGVLRALGLTPYLH
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHH
QQRALKRVEAGANVVLAYPTAAGKSLVYQAPVLQAALEGATSLLLFPTKALAHDQLRRLR
HHHHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHH
AMAQVLGVEGVFPYDGDTPSATRRQARERGLVLLSNPDMLHYGLLPRHPDWAPFLARLRY
HHHHHHCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCEEEECCCCCCCCHHHHHHHHHH
VVLDELHAYRGVFGTHVALILRRLLRLARHYGASPQVLAASATIANAREHAEALTGLPFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCCHH
ELKAQVARTERELLVLLPKPLDRRGERRRSPLLEAAYLARRLAEAGLKGLVFAGARKSAE
HHHHHHHHCCCCEEEECCCCCCCCHHHHHCHHHHHHHHHHHHHHCCCCEEEEECCCHHHH
LIARYAAHPLVRPYRAGYTARERRRLEADLKEGRVRVLVSTSALELGVDIGELDAVVLVG
HHHHHHHCCCCCHHHCCCCHHHHHHHHHHHCCCCEEEEEEECHHHHCCCCCCCCEEEEEE
YPGSTAAFWQRAGRAGRGERRALLVYIPREDPMDEYFLHRPALLLESPPEEAVADPQNPV
CCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHCCHHEECCCCHHHHCCCCCCE
LCPLHLHAAAREKPLLAEELLCPEARATLKERNGRFFTPKRNPHREITLRGLGATFTLRG
EEEEEHHHHHCCCCCHHHHHCCCHHHHHHHHCCCCEECCCCCCCCEEEEEECCEEEEEEC
PDGEVLGYLDERQAYWEAHPGAIYLHQGESYLVRNVDLARREVWLLPALEDYYTEPRAET
CCCCEEEEHHHHHHHHCCCCCEEEEECCCCEEEECCHHHHHHEEEECCHHHHCCCCCCCC
DLEVLSGEEVGPGVWVGRVVLRERVVGYVKKRFYTGSVLEEVPLEMPEVSFPTEALWFHP
CHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCEEEECC
PEAVPAFQIPGGIHALEHAMIGLLPLFVLAERQDVGGISYPFYPRPLPSPGGPTVFIYDG
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECC
YPGGVGYARRAARRFPEWLKATLDLLRSCPCEEGCPRCVLSPKCGNGNQYLDKKAALALA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHH
LALAHPLD
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]