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The map label for this gene is mrdB [H]

Identifier: 55981210

GI number: 55981210

Start: 1177023

End: 1178102

Strand: Reverse

Name: mrdB [H]

Synonym: TTHA1241

Alternate gene names: 55981210

Gene position: 1178102-1177023 (Counterclockwise)

Preceding gene: 55981211

Following gene: 55981209

Centisome position: 63.69

GC content: 70.09

Gene sequence:

>1080_bases
GTGGCGCCCGCGCGGCCCAACTGGCTGGCCTACGACTGGGGCCTCGTCTTCCTGGTCGCGGCCATCGTCGCTTTGGGCTT
TGTCAACCTGGGGAGCGCCGCCCCCGACCCGGTCCTCCTCTACCGCCAGAGCGTGGCCCTGGGGCTTGGGCTTCTCCTCG
CCTTCCTCTTGCAGTTCCTCTCCCGCCGCCGCCTCTTCGGCCTGGCCTATCCCCTTTACGGGGCCTCCCTCCTTCTCCTG
GCCTTGGTCCTCGTGGTGGGCCGGGAGATCAACGGGGCCAGGGCCTGGTTCGTGCTGGGACCCTTGCAGTTCCAGCCCTT
GGAGCTCGCCAAGCTCGGCCTCCTCCTCGCCCTGGCCAAGGCCCTCGAGGGCAGGCCCATCGCCCGGGTCTGGGACTACG
CCCTCCCCGCCCTCCTCACCCTCCCCGTGGTGGGCCTCCTCCTCCTCCAGCCGGACCTGGGCGGGGCGCTGGTGGTGCTC
TTCGGCGTCTTCGTGGTGGTCTTCGTCCGCGGGCTTCCCTGGCGCCACCTCCTCGTGGGCCTCTTCGCCCTGGCCCTCCT
CGTGCCCACCGCGGTGTGGCCCAACCTCAAGCCCTACCAGAGGGAGCGCGTCCTCATCGTCCTGGACCCTTACCGGGACC
CTTTGGGCCAGGGCTTCCAGGTCATCCAGTCCACCATCGCCATCGGCTCGGGGGGGCTTTTCGGCAAGGGCTACGGCCAG
GGCACCCAGGCCCAGCTCGGCTTCATCCCCTTCCGGCACACGGACTTCGTCTTCTCCGTGTGGGCCGAGGAGTGGGGGTT
CGTGGGCGTCGTGGGGCTTCTGGGGCTTTACGGCCTCCTTCTCGCCCGCCTCTTCGCCCTGGCCCTCGCCTGCCCGAGGC
TTTCCGACCGGCTTTTCCTCTCGGGGTTCGCGGGGATGCTGGGCTTCCAGGTGGTGGTGAACCTGGGGGTGGCCCTGGGG
GTGATGCCCGTCACCGGCCTCACCCTCCCCCTCTTTTCCTACGGCGGCTCCAGCCTCATCGCCACCCTGGCGGGCTTGGG
CCTCGTCCTCCTCGTGCACCGGGACCGCTACCAGGACTGA

Upstream 100 bases:

>100_bases
ACTTCCCCGCCCAGGAGGAGGGGCTTTCCGTGGCCCTGGAGGAGCGGGGGGAGAAGATGGTCCTGGTGGCGGACATCCCC
TTGCGCTAGCGGGGTAGGCC

Downstream 100 bases:

>100_bases
GCCTTTTCGGGGTGCCAGGCCTGGGGTTGCCCCCCGGGGCGGCGCGCCCTAAACTGGGCGTCGTGGCCGAGGTGCTGGTG
CGTCTCCAGGGGGTGCGGAA

Product: rod shape determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MAPARPNWLAYDWGLVFLVAAIVALGFVNLGSAAPDPVLLYRQSVALGLGLLLAFLLQFLSRRRLFGLAYPLYGASLLLL
ALVLVVGREINGARAWFVLGPLQFQPLELAKLGLLLALAKALEGRPIARVWDYALPALLTLPVVGLLLLQPDLGGALVVL
FGVFVVVFVRGLPWRHLLVGLFALALLVPTAVWPNLKPYQRERVLIVLDPYRDPLGQGFQVIQSTIAIGSGGLFGKGYGQ
GTQAQLGFIPFRHTDFVFSVWAEEWGFVGVVGLLGLYGLLLARLFALALACPRLSDRLFLSGFAGMLGFQVVVNLGVALG
VMPVTGLTLPLFSYGGSSLIATLAGLGLVLLVHRDRYQD

Sequences:

>Translated_359_residues
MAPARPNWLAYDWGLVFLVAAIVALGFVNLGSAAPDPVLLYRQSVALGLGLLLAFLLQFLSRRRLFGLAYPLYGASLLLL
ALVLVVGREINGARAWFVLGPLQFQPLELAKLGLLLALAKALEGRPIARVWDYALPALLTLPVVGLLLLQPDLGGALVVL
FGVFVVVFVRGLPWRHLLVGLFALALLVPTAVWPNLKPYQRERVLIVLDPYRDPLGQGFQVIQSTIAIGSGGLFGKGYGQ
GTQAQLGFIPFRHTDFVFSVWAEEWGFVGVVGLLGLYGLLLARLFALALACPRLSDRLFLSGFAGMLGFQVVVNLGVALG
VMPVTGLTLPLFSYGGSSLIATLAGLGLVLLVHRDRYQD
>Mature_358_residues
APARPNWLAYDWGLVFLVAAIVALGFVNLGSAAPDPVLLYRQSVALGLGLLLAFLLQFLSRRRLFGLAYPLYGASLLLLA
LVLVVGREINGARAWFVLGPLQFQPLELAKLGLLLALAKALEGRPIARVWDYALPALLTLPVVGLLLLQPDLGGALVVLF
GVFVVVFVRGLPWRHLLVGLFALALLVPTAVWPNLKPYQRERVLIVLDPYRDPLGQGFQVIQSTIAIGSGGLFGKGYGQG
TQAQLGFIPFRHTDFVFSVWAEEWGFVGVVGLLGLYGLLLARLFALALACPRLSDRLFLSGFAGMLGFQVVVNLGVALGV
MPVTGLTLPLFSYGGSSLIATLAGLGLVLLVHRDRYQD

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=329, Percent_Identity=39.209726443769, Blast_Score=181, Evalue=5e-47,
Organism=Escherichia coli, GI1786277, Length=370, Percent_Identity=33.5135135135135, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 38663; Mature: 38532

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPARPNWLAYDWGLVFLVAAIVALGFVNLGSAAPDPVLLYRQSVALGLGLLLAFLLQFL
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SRRRLFGLAYPLYGASLLLLALVLVVGREINGARAWFVLGPLQFQPLELAKLGLLLALAK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
ALEGRPIARVWDYALPALLTLPVVGLLLLQPDLGGALVVLFGVFVVVFVRGLPWRHLLVG
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
LFALALLVPTAVWPNLKPYQRERVLIVLDPYRDPLGQGFQVIQSTIAIGSGGLFGKGYGQ
HHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
GTQAQLGFIPFRHTDFVFSVWAEEWGFVGVVGLLGLYGLLLARLFALALACPRLSDRLFL
CCCCEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
SGFAGMLGFQVVVNLGVALGVMPVTGLTLPLFSYGGSSLIATLAGLGLVLLVHRDRYQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
APARPNWLAYDWGLVFLVAAIVALGFVNLGSAAPDPVLLYRQSVALGLGLLLAFLLQFL
CCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SRRRLFGLAYPLYGASLLLLALVLVVGREINGARAWFVLGPLQFQPLELAKLGLLLALAK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
ALEGRPIARVWDYALPALLTLPVVGLLLLQPDLGGALVVLFGVFVVVFVRGLPWRHLLVG
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
LFALALLVPTAVWPNLKPYQRERVLIVLDPYRDPLGQGFQVIQSTIAIGSGGLFGKGYGQ
HHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
GTQAQLGFIPFRHTDFVFSVWAEEWGFVGVVGLLGLYGLLLARLFALALACPRLSDRLFL
CCCCEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
SGFAGMLGFQVVVNLGVALGVMPVTGLTLPLFSYGGSSLIATLAGLGLVLLVHRDRYQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]