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The map label for this gene is fabG [H]

Identifier: 55981202

GI number: 55981202

Start: 1170395

End: 1171129

Strand: Direct

Name: fabG [H]

Synonym: TTHA1233

Alternate gene names: 55981202

Gene position: 1170395-1171129 (Clockwise)

Preceding gene: 55981201

Following gene: 55981203

Centisome position: 63.27

GC content: 71.56

Gene sequence:

>735_bases
ATGAGGAAGACCCTGATCCTCACCGGGGCGAGCCGGGGCATCGGGAAGGCCCTCGCCCTGGAGCTCGCCAAGGAAGGCTT
TGACCTGGTGCTCAACGCCCGCAAGGAGGCCTCCTTGCGGGCGGTGGCCGAGGAGGTCCAGGCCCTGGGGGCGAGGGCGG
TCTACGTGGCGGGGAGCGCGGGGAAGGCGGAGGTGGCCCACGCCCTGGTGGAAAGGGCCGAGGCCTTGGGGAACTTCGCG
GGCTACATCCACAACGCCGGGGTCCTCCACCCGGGGCCCCTCCTCTTTGAACTCGCGGAGGAGCTCTTCCTGGAGGTCCT
CGAGGCCAACCTCCTCGCCGGCTACCAGCTCGCCCGCTTCGCCTACCCCGTCCTCAGGCGCAAAGGGGAAGGCCTCGCCG
TGTACGTGGGCTCGGGGGCGGCGGAGAGCAACCTGCCGGGCATCGGGGCCTACGCCGTGGCCAAGGCGGCGGAGGAGCAC
CTGGCAAGGCAGCTCGCCGCCGAGGCCCCGGAGGTCGCCTGCTTCGTCTACCGCCCCGGGGTGGTGGAGACGGAGATGCA
GCGCCAGGCCCGGGAGGCCCAGGGAAGCGCCGCGGCCGTGCTCCACCGGGTCTTCAGGAGCTACAAGGAGGAAGGCCTCC
TCCTCACCCCGGAGGAGGCCGCGAGGGCCCTGGTGCGGCTTCTCCCCAAGGCCAGGGCCTTCCACGGAAAGATCGCCACC
TGGAGGGACGCATGA

Upstream 100 bases:

>100_bases
ACAGAAAGCCCGAAGGCGGGGGCTACCGGGAGGCGGAGGCCCTGGGCCCCGGGGCCAGGCTTTCCTTCCACGGCGTGGAG
ATCCCCGCGGAGGAACTCCT

Downstream 100 bases:

>100_bases
GGTCGGACCAGATCAAGAAGGGACTCAAGCAGGCCCCCGCCCGCGCCATGCTCCGGGCGGTGGGGGTAGGGGACGAGGAC
TTCGGAAGGCCCTTCGTGGG

Product: short-chain dehydrogenase/reductase family protein

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MRKTLILTGASRGIGKALALELAKEGFDLVLNARKEASLRAVAEEVQALGARAVYVAGSAGKAEVAHALVERAEALGNFA
GYIHNAGVLHPGPLLFELAEELFLEVLEANLLAGYQLARFAYPVLRRKGEGLAVYVGSGAAESNLPGIGAYAVAKAAEEH
LARQLAAEAPEVACFVYRPGVVETEMQRQAREAQGSAAAVLHRVFRSYKEEGLLLTPEEAARALVRLLPKARAFHGKIAT
WRDA

Sequences:

>Translated_244_residues
MRKTLILTGASRGIGKALALELAKEGFDLVLNARKEASLRAVAEEVQALGARAVYVAGSAGKAEVAHALVERAEALGNFA
GYIHNAGVLHPGPLLFELAEELFLEVLEANLLAGYQLARFAYPVLRRKGEGLAVYVGSGAAESNLPGIGAYAVAKAAEEH
LARQLAAEAPEVACFVYRPGVVETEMQRQAREAQGSAAAVLHRVFRSYKEEGLLLTPEEAARALVRLLPKARAFHGKIAT
WRDA
>Mature_244_residues
MRKTLILTGASRGIGKALALELAKEGFDLVLNARKEASLRAVAEEVQALGARAVYVAGSAGKAEVAHALVERAEALGNFA
GYIHNAGVLHPGPLLFELAEELFLEVLEANLLAGYQLARFAYPVLRRKGEGLAVYVGSGAAESNLPGIGAYAVAKAAEEH
LARQLAAEAPEVACFVYRPGVVETEMQRQAREAQGSAAAVLHRVFRSYKEEGLLLTPEEAARALVRLLPKARAFHGKIAT
WRDA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI226371731, Length=186, Percent_Identity=27.4193548387097, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI209862901, Length=200, Percent_Identity=28.5, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI19923983, Length=200, Percent_Identity=28.5, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI32483357, Length=192, Percent_Identity=30.7291666666667, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=29.8969072164948, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI210032110, Length=165, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI5031737, Length=191, Percent_Identity=29.8429319371728, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=197, Percent_Identity=29.4416243654822, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786812, Length=191, Percent_Identity=30.3664921465969, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787905, Length=242, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786701, Length=199, Percent_Identity=27.6381909547739, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI1787526, Length=191, Percent_Identity=28.2722513089005, Blast_Score=60, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71994604, Length=208, Percent_Identity=30.2884615384615, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=237, Percent_Identity=29.957805907173, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=190, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6322226, Length=241, Percent_Identity=33.6099585062241, Blast_Score=99, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6322227, Length=258, Percent_Identity=30.6201550387597, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24644339, Length=191, Percent_Identity=31.9371727748691, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357041, Length=191, Percent_Identity=35.0785340314136, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI161076933, Length=193, Percent_Identity=28.4974093264249, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24584752, Length=191, Percent_Identity=31.9371727748691, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24584748, Length=193, Percent_Identity=28.4974093264249, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24584744, Length=186, Percent_Identity=27.4193548387097, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28574402, Length=195, Percent_Identity=27.6923076923077, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571526, Length=191, Percent_Identity=32.9842931937173, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI23397609, Length=210, Percent_Identity=33.8095238095238, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355319, Length=224, Percent_Identity=26.7857142857143, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21356301, Length=238, Percent_Identity=26.0504201680672, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26035; Mature: 26035

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKTLILTGASRGIGKALALELAKEGFDLVLNARKEASLRAVAEEVQALGARAVYVAGSA
CCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEECCC
GKAEVAHALVERAEALGNFAGYIHNAGVLHPGPLLFELAEELFLEVLEANLLAGYQLARF
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYPVLRRKGEGLAVYVGSGAAESNLPGIGAYAVAKAAEEHLARQLAAEAPEVACFVYRPG
HHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
VVETEMQRQAREAQGSAAAVLHRVFRSYKEEGLLLTPEEAARALVRLLPKARAFHGKIAT
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHCCCCCC
WRDA
CCCC
>Mature Secondary Structure
MRKTLILTGASRGIGKALALELAKEGFDLVLNARKEASLRAVAEEVQALGARAVYVAGSA
CCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEECCC
GKAEVAHALVERAEALGNFAGYIHNAGVLHPGPLLFELAEELFLEVLEANLLAGYQLARF
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYPVLRRKGEGLAVYVGSGAAESNLPGIGAYAVAKAAEEHLARQLAAEAPEVACFVYRPG
HHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
VVETEMQRQAREAQGSAAAVLHRVFRSYKEEGLLLTPEEAARALVRLLPKARAFHGKIAT
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHCCCCCC
WRDA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]