Click here to switch to the map view.

The map label for this gene is engD [H]

Identifier: 55981154

GI number: 55981154

Start: 1131928

End: 1133034

Strand: Reverse

Name: engD [H]

Synonym: TTHA1185

Alternate gene names: 55981154

Gene position: 1133034-1131928 (Counterclockwise)

Preceding gene: 55981162

Following gene: 55981153

Centisome position: 61.25

GC content: 69.65

Gene sequence:

>1107_bases
ATGCTTGCCGTAGGAATCGTAGGTCTACCCAACGTGGGCAAGTCCACCCTCTTCAACGCCCTCACCCGGGCGAACGCCCT
CGCCGCCAACTACCCCTTCGCCACCATAGACAAGAACGTGGGGGTGGTGCCCCTGGAGGACGAGCGGCTTTACGCCCTGC
AGCGGACCTTCGCCAAGGGGGAGCGGGTTCCGCCCGTGGTGCCCACCCACGTGGAGTTCGTGGACATCGCCGGGCTCGTC
AAGGGGGCCCACAAAGGGGAGGGCTTGGGCAACCAGTTCCTGGCCCACATCCGCGAGGTGGCGGCCATCGCCCACGTCCT
CCGTTGCTTCCCCGACCCCGACGTGGTCCACGTCATGGGCCGGGTGGACCCCTTGGAGGACGCCGAGGTGGTGGAGACGG
AGCTCCTCCTCGCCGACCTCGCCACCCTGGAGAGGCGGCTTGAGCGCCTAAGGAAGGAGGCGAGGGCCGACCGGGAGAGG
CTTCCCCTCTTGGAGGCGGCGGAAGGCCTTTACGTTCACCTCCAGGAAGGCAAGCCCGCCCGCACCTTCCCCCCTTCCGA
GGCGGTGGCCCGCTTTCTGAAGGAAACCCCCCTCCTCACCGCCAAGCCCGTGATCTACGTGGCCAACGTGGCCGAGGAGG
ACCTGCCCGACGGCCGGGGAAACCCCCAGGTGGAGGCGGTGCGGCGGAAAGCCCTGGAGGAGGGGGCCGAGGTGGTGGTG
GTCTCGGCGAGGCTCGAGGCCGAGCTCGCCGAGCTCTCCGGGGAGGAGGCGAGGGAGCTTCTCGCCGCCTACGGCCTCCA
GGAAAGCGGCCTCCAGCGCCTCGCCCGGGCGGGCTACCGCGCCCTAGACCTCCTCACCTTCTTCACCGCCGGGGAGAAGG
AGGTGCGGGCCTGGACCGTGCGCCGGGGGACCAAGGCGCCAAGGGCCGCCGGGGAGATCCACTCCGACATGGAGCGGGGC
TTCATCCGGGCCGAAGTCATCCCCTGGGACAAGCTGGTGGAGGCCGGGGGGTGGGCGAGGGCCAAGGAGCGGGGCTGGGT
GCGCCTCGAGGGCAAGGACTACGAGGTCCAGGACGGGGATGTGATCTACGTCCTGTTCAACGCCTAG

Upstream 100 bases:

>100_bases
TGGTCAATGTGGGCGGCCAGGTCCATACCCCGCCATCATACGAGACCCACGTGATAGGATGGAAAGAGGCCCCGCTTGGG
GCTTTTTTTGAGGTCCTAAG

Downstream 100 bases:

>100_bases
CCTTTTCCCAGACTGGCCTTATGGCCGCGACCGTGCGGGTGGAACTTTCCCAGGTGGGTCCCTCCACCTCGGAGGGGGTG
GTGCGGGGGAAGCACCGCGT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MLAVGIVGLPNVGKSTLFNALTRANALAANYPFATIDKNVGVVPLEDERLYALQRTFAKGERVPPVVPTHVEFVDIAGLV
KGAHKGEGLGNQFLAHIREVAAIAHVLRCFPDPDVVHVMGRVDPLEDAEVVETELLLADLATLERRLERLRKEARADRER
LPLLEAAEGLYVHLQEGKPARTFPPSEAVARFLKETPLLTAKPVIYVANVAEEDLPDGRGNPQVEAVRRKALEEGAEVVV
VSARLEAELAELSGEEARELLAAYGLQESGLQRLARAGYRALDLLTFFTAGEKEVRAWTVRRGTKAPRAAGEIHSDMERG
FIRAEVIPWDKLVEAGGWARAKERGWVRLEGKDYEVQDGDVIYVLFNA

Sequences:

>Translated_368_residues
MLAVGIVGLPNVGKSTLFNALTRANALAANYPFATIDKNVGVVPLEDERLYALQRTFAKGERVPPVVPTHVEFVDIAGLV
KGAHKGEGLGNQFLAHIREVAAIAHVLRCFPDPDVVHVMGRVDPLEDAEVVETELLLADLATLERRLERLRKEARADRER
LPLLEAAEGLYVHLQEGKPARTFPPSEAVARFLKETPLLTAKPVIYVANVAEEDLPDGRGNPQVEAVRRKALEEGAEVVV
VSARLEAELAELSGEEARELLAAYGLQESGLQRLARAGYRALDLLTFFTAGEKEVRAWTVRRGTKAPRAAGEIHSDMERG
FIRAEVIPWDKLVEAGGWARAKERGWVRLEGKDYEVQDGDVIYVLFNA
>Mature_368_residues
MLAVGIVGLPNVGKSTLFNALTRANALAANYPFATIDKNVGVVPLEDERLYALQRTFAKGERVPPVVPTHVEFVDIAGLV
KGAHKGEGLGNQFLAHIREVAAIAHVLRCFPDPDVVHVMGRVDPLEDAEVVETELLLADLATLERRLERLRKEARADRER
LPLLEAAEGLYVHLQEGKPARTFPPSEAVARFLKETPLLTAKPVIYVANVAEEDLPDGRGNPQVEAVRRKALEEGAEVVV
VSARLEAELAELSGEEARELLAAYGLQESGLQRLARAGYRALDLLTFFTAGEKEVRAWTVRRGTKAPRAAGEIHSDMERG
FIRAEVIPWDKLVEAGGWARAKERGWVRLEGKDYEVQDGDVIYVLFNA

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=373, Percent_Identity=41.2868632707775, Blast_Score=270, Evalue=1e-72,
Organism=Homo sapiens, GI58761502, Length=198, Percent_Identity=39.3939393939394, Blast_Score=138, Evalue=1e-32,
Organism=Escherichia coli, GI1787454, Length=369, Percent_Identity=50.4065040650407, Blast_Score=343, Evalue=1e-95,
Organism=Escherichia coli, GI1789574, Length=146, Percent_Identity=32.1917808219178, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17509631, Length=371, Percent_Identity=40.9703504043127, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17508313, Length=107, Percent_Identity=35.5140186915888, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319499, Length=372, Percent_Identity=39.247311827957, Blast_Score=232, Evalue=7e-62,
Organism=Saccharomyces cerevisiae, GI6321773, Length=386, Percent_Identity=35.4922279792746, Blast_Score=199, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6321649, Length=359, Percent_Identity=28.133704735376, Blast_Score=83, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24640873, Length=376, Percent_Identity=41.4893617021277, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24640877, Length=376, Percent_Identity=41.4893617021277, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24640875, Length=376, Percent_Identity=41.4893617021277, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24640879, Length=335, Percent_Identity=39.4029850746269, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI20129375, Length=107, Percent_Identity=39.2523364485981, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585318, Length=145, Percent_Identity=31.0344827586207, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40511; Mature: 40511

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAVGIVGLPNVGKSTLFNALTRANALAANYPFATIDKNVGVVPLEDERLYALQRTFAKG
CEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCEEECCCCHHHHHHHHHHCC
ERVPPVVPTHVEFVDIAGLVKGAHKGEGLGNQFLAHIREVAAIAHVLRCFPDPDVVHVMG
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCC
RVDPLEDAEVVETELLLADLATLERRLERLRKEARADRERLPLLEAAEGLYVHLQEGKPA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCC
RTFPPSEAVARFLKETPLLTAKPVIYVANVAEEDLPDGRGNPQVEAVRRKALEEGAEVVV
CCCCCHHHHHHHHHHCCCCEECCEEEEECCHHHCCCCCCCCCHHHHHHHHHHHCCCCEEE
VSARLEAELAELSGEEARELLAAYGLQESGLQRLARAGYRALDLLTFFTAGEKEVRAWTV
EEHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHEEEE
RRGTKAPRAAGEIHSDMERGFIRAEVIPWDKLVEAGGWARAKERGWVRLEGKDYEVQDGD
CCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHCCCCCCHHHCCEEEECCCCEEECCCC
VIYVLFNA
EEEEEECC
>Mature Secondary Structure
MLAVGIVGLPNVGKSTLFNALTRANALAANYPFATIDKNVGVVPLEDERLYALQRTFAKG
CEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCEEECCCCHHHHHHHHHHCC
ERVPPVVPTHVEFVDIAGLVKGAHKGEGLGNQFLAHIREVAAIAHVLRCFPDPDVVHVMG
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCC
RVDPLEDAEVVETELLLADLATLERRLERLRKEARADRERLPLLEAAEGLYVHLQEGKPA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCC
RTFPPSEAVARFLKETPLLTAKPVIYVANVAEEDLPDGRGNPQVEAVRRKALEEGAEVVV
CCCCCHHHHHHHHHHCCCCEECCEEEEECCHHHCCCCCCCCCHHHHHHHHHHHCCCCEEE
VSARLEAELAELSGEEARELLAAYGLQESGLQRLARAGYRALDLLTFFTAGEKEVRAWTV
EEHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHEEEE
RRGTKAPRAAGEIHSDMERGFIRAEVIPWDKLVEAGGWARAKERGWVRLEGKDYEVQDGD
CCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHCCCCCCHHHCCEEEECCCCEEECCCC
VIYVLFNA
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]