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The map label for this gene is rnjA [H]

Identifier: 55981109

GI number: 55981109

Start: 1082096

End: 1083817

Strand: Direct

Name: rnjA [H]

Synonym: TTHA1140

Alternate gene names: 55981109

Gene position: 1082096-1083817 (Clockwise)

Preceding gene: 55981108

Following gene: 55981113

Centisome position: 58.5

GC content: 66.96

Gene sequence:

>1722_bases
ATGGAAAACCAAGAACGGAAGCCGAGGAGGAGGCGCCGGCGGAGGCCCCAGGAAGGGTCCCAAGGCGGCCCCCAGGACCA
CGTGGAGATCATCCCCTTGGGGGGGATGGGGGAGATCGGGAAGAACATCACCGTCTTCCGCTTCCGGGACGAGATCTTCG
TCCTGGACGGAGGGCTCGCCTTCCCTGAGGAGGGGATGCCCGGGGTGGACCTCCTCATCCCCCGGGTGGACTACCTCATA
GAGCACCGCCACAAGATCAAGGCCTGGGTCCTCACCCACGGGCACGAGGACCACATCGGGGGGCTTCCCTTCCTCCTCCC
CATGATCTTCGGCAAGGAGAGCCCGGTGCCCATCTACGGGGCGAGGCTCACCCTGGGGCTCCTCCGGGGCAAGCTTGAGG
AGTTCGGCCTGAGGCCCGGGGCCTTCAACCTGAAGGAGATCTCCCCCGACGACCGCATCCAGGTGGGGCGGTACTTCACC
CTGGACCTTTTCCGCATGACCCACTCCATCCCCGACAACTCCGGGGTGGTGATCCGCACCCCCATCGGCACCATCGTCCA
CACGGGGGACTTCAAGCTGGACCCCACCCCCATTGACGGGAAGGTCTCCCACCTGGCCAAGGTGGCCCAGGCGGGGGCGG
AAGGGGTGCTCCTCCTCATCGCCGACGCCACCAACGCCGAAAGGCCCGGCTACACCCCAAGCGAGATGGAGATCGCCAAG
GAGCTGGACCGGGTCATCGGCCGCGCCCCAGGGCGGGTCTTCGTCACCACCTTCGCCAGCCACATCCACCGCATCCAGTC
GGTGATCTGGGCGGCGGAGAAGTACGGGCGCAAGGTGGCCATGGAGGGGCGGAGCATGCTCAAGTTCAGCCGCATCGCCC
TGGAGCTCGGCTACCTCAAGGTCAAGGACCGCCTCTACACCCTGGAGGAAGTGAAGGACCTCCCCGACCACCAGGTCCTC
ATCCTGGCCACGGGGAGCCAGGGCCAGCCCATGTCCGTCCTCCACCGCCTGGCCTTTGAGGGGCACGCCAAGATGGCCAT
CAAGCCCGGGGACACGGTGATCCTCTCCTCAAGCCCCATCCCGGGGAACGAGGAGGCGGTGAACCGGGTCATCAACCGCC
TTTACGCCCTGGGGGCCTACGTCCTCTACCCCCCGACCTACAAGGTCCACGCCTCGGGCCACGCCTCCCAGGAAGAGCTG
AAGCTCATCCTCAACCTCACCACCCCCCGCTTCTTCCTGCCGTGGCACGGGGAGGTGCGGCACCAGATGAACTTCAAGTG
GCTCGCCGAGTCCATGAGCCGCCCCCCGGAGAAGACCCTCATCGGGGAGAACGGGGCCGTTTACCGCCTCACCCGGGAAA
CCTTTGAGAAGGTGGGGGAAGTGCCCCACGGGGTCCTCTACGTGGACGGCCTGGGGGTGGGGGACATTACCGAGGAGATC
CTGGCCGACCGCCGCCACATGGCCGAGGAGGGCCTGGTGGTGATCACCGCCCTCGCCGGGGAGGACCCGGTGGTGGAGGT
GGTCTCCCGGGGGTTCGTGAAGGCCGGGGAGCGGCTTCTCGGCGAGGTGCGGCGCATGGCCCTCGAGGCCCTGAAGAACG
GGGTGCGGGAGAAGAAGCCCCTGGAGCGGATCCGGGACGACATCTACTACCCGGTGAAGAAGTTCCTGAAGAAGGCCACG
GGCCGGGACCCCATGATCCTGCCCGTGGTCATAGAGGGGTAG

Upstream 100 bases:

>100_bases
GCCCCGAGCTGGAAGGCAAGATCCCCCCCAGGCGGCGCAGGTAGCCCCTGGGGGCTTGACCTCACGCGCGTCCCGGCCAG
GCCGGGAAGATGGGAGGCGT

Downstream 100 bases:

>100_bases
GCCTTTCCCCTACCGGGGGGGCGCGTAGGCCGCCCCCCGTTTCCACACCGCCCGGTCCACCGCCTCCGCCAGGGCGAAGG
CCAGGAGGGCCATCCCGAAA

Product: metallo-beta-lactamase

Products: NA

Alternate protein names: RNase J1 [H]

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MENQERKPRRRRRRRPQEGSQGGPQDHVEIIPLGGMGEIGKNITVFRFRDEIFVLDGGLAFPEEGMPGVDLLIPRVDYLI
EHRHKIKAWVLTHGHEDHIGGLPFLLPMIFGKESPVPIYGARLTLGLLRGKLEEFGLRPGAFNLKEISPDDRIQVGRYFT
LDLFRMTHSIPDNSGVVIRTPIGTIVHTGDFKLDPTPIDGKVSHLAKVAQAGAEGVLLLIADATNAERPGYTPSEMEIAK
ELDRVIGRAPGRVFVTTFASHIHRIQSVIWAAEKYGRKVAMEGRSMLKFSRIALELGYLKVKDRLYTLEEVKDLPDHQVL
ILATGSQGQPMSVLHRLAFEGHAKMAIKPGDTVILSSSPIPGNEEAVNRVINRLYALGAYVLYPPTYKVHASGHASQEEL
KLILNLTTPRFFLPWHGEVRHQMNFKWLAESMSRPPEKTLIGENGAVYRLTRETFEKVGEVPHGVLYVDGLGVGDITEEI
LADRRHMAEEGLVVITALAGEDPVVEVVSRGFVKAGERLLGEVRRMALEALKNGVREKKPLERIRDDIYYPVKKFLKKAT
GRDPMILPVVIEG

Sequences:

>Translated_573_residues
MENQERKPRRRRRRRPQEGSQGGPQDHVEIIPLGGMGEIGKNITVFRFRDEIFVLDGGLAFPEEGMPGVDLLIPRVDYLI
EHRHKIKAWVLTHGHEDHIGGLPFLLPMIFGKESPVPIYGARLTLGLLRGKLEEFGLRPGAFNLKEISPDDRIQVGRYFT
LDLFRMTHSIPDNSGVVIRTPIGTIVHTGDFKLDPTPIDGKVSHLAKVAQAGAEGVLLLIADATNAERPGYTPSEMEIAK
ELDRVIGRAPGRVFVTTFASHIHRIQSVIWAAEKYGRKVAMEGRSMLKFSRIALELGYLKVKDRLYTLEEVKDLPDHQVL
ILATGSQGQPMSVLHRLAFEGHAKMAIKPGDTVILSSSPIPGNEEAVNRVINRLYALGAYVLYPPTYKVHASGHASQEEL
KLILNLTTPRFFLPWHGEVRHQMNFKWLAESMSRPPEKTLIGENGAVYRLTRETFEKVGEVPHGVLYVDGLGVGDITEEI
LADRRHMAEEGLVVITALAGEDPVVEVVSRGFVKAGERLLGEVRRMALEALKNGVREKKPLERIRDDIYYPVKKFLKKAT
GRDPMILPVVIEG
>Mature_573_residues
MENQERKPRRRRRRRPQEGSQGGPQDHVEIIPLGGMGEIGKNITVFRFRDEIFVLDGGLAFPEEGMPGVDLLIPRVDYLI
EHRHKIKAWVLTHGHEDHIGGLPFLLPMIFGKESPVPIYGARLTLGLLRGKLEEFGLRPGAFNLKEISPDDRIQVGRYFT
LDLFRMTHSIPDNSGVVIRTPIGTIVHTGDFKLDPTPIDGKVSHLAKVAQAGAEGVLLLIADATNAERPGYTPSEMEIAK
ELDRVIGRAPGRVFVTTFASHIHRIQSVIWAAEKYGRKVAMEGRSMLKFSRIALELGYLKVKDRLYTLEEVKDLPDHQVL
ILATGSQGQPMSVLHRLAFEGHAKMAIKPGDTVILSSSPIPGNEEAVNRVINRLYALGAYVLYPPTYKVHASGHASQEEL
KLILNLTTPRFFLPWHGEVRHQMNFKWLAESMSRPPEKTLIGENGAVYRLTRETFEKVGEVPHGVLYVDGLGVGDITEEI
LADRRHMAEEGLVVITALAGEDPVVEVVSRGFVKAGERLLGEVRRMALEALKNGVREKKPLERIRDDIYYPVKKFLKKAT
GRDPMILPVVIEG

Specific function: Cleaves the 5'-leader sequence of certain mRNAs. May play a role in maturation and stability of specific mRNAs. Is also required for the maturation of the 16S rRNA. Acts preferentially on 16S rRNA precursors after association of the 30S and 50S ribosomal

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR004613
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 64032; Mature: 64032

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENQERKPRRRRRRRPQEGSQGGPQDHVEIIPLGGMGEIGKNITVFRFRDEIFVLDGGLA
CCCCCCCHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECEEEEEECCCC
FPEEGMPGVDLLIPRVDYLIEHRHKIKAWVLTHGHEDHIGGLPFLLPMIFGKESPVPIYG
CCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCEEH
ARLTLGLLRGKLEEFGLRPGAFNLKEISPDDRIQVGRYFTLDLFRMTHSIPDNSGVVIRT
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCEEEHHHHHHHHCCCCCCCEEEEE
PIGTIVHTGDFKLDPTPIDGKVSHLAKVAQAGAEGVLLLIADATNAERPGYTPSEMEIAK
CCCEEEECCCCEECCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHH
ELDRVIGRAPGRVFVTTFASHIHRIQSVIWAAEKYGRKVAMEGRSMLKFSRIALELGYLK
HHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHEE
VKDRLYTLEEVKDLPDHQVLILATGSQGQPMSVLHRLAFEGHAKMAIKPGDTVILSSSPI
HHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCEEEEECCCC
PGNEEAVNRVINRLYALGAYVLYPPTYKVHASGHASQEELKLILNLTTPRFFLPWHGEVR
CCCHHHHHHHHHHHHHHCCEEEECCCEEEECCCCCCHHHEEEEEEECCCEEEECCCCCHH
HQMNFKWLAESMSRPPEKTLIGENGAVYRLTRETFEKVGEVPHGVLYVDGLGVGDITEEI
HHCCHHHHHHHHCCCCCCEEECCCCCEEEEEHHHHHHHHCCCCCEEEEECCCCCHHHHHH
LADRRHMAEEGLVVITALAGEDPVVEVVSRGFVKAGERLLGEVRRMALEALKNGVREKKP
HHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
LERIRDDIYYPVKKFLKKATGRDPMILPVVIEG
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
>Mature Secondary Structure
MENQERKPRRRRRRRPQEGSQGGPQDHVEIIPLGGMGEIGKNITVFRFRDEIFVLDGGLA
CCCCCCCHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECEEEEEECCCC
FPEEGMPGVDLLIPRVDYLIEHRHKIKAWVLTHGHEDHIGGLPFLLPMIFGKESPVPIYG
CCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCEEH
ARLTLGLLRGKLEEFGLRPGAFNLKEISPDDRIQVGRYFTLDLFRMTHSIPDNSGVVIRT
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCEEEHHHHHHHHCCCCCCCEEEEE
PIGTIVHTGDFKLDPTPIDGKVSHLAKVAQAGAEGVLLLIADATNAERPGYTPSEMEIAK
CCCEEEECCCCEECCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHH
ELDRVIGRAPGRVFVTTFASHIHRIQSVIWAAEKYGRKVAMEGRSMLKFSRIALELGYLK
HHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHEE
VKDRLYTLEEVKDLPDHQVLILATGSQGQPMSVLHRLAFEGHAKMAIKPGDTVILSSSPI
HHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCEEEEECCCC
PGNEEAVNRVINRLYALGAYVLYPPTYKVHASGHASQEELKLILNLTTPRFFLPWHGEVR
CCCHHHHHHHHHHHHHHCCEEEECCCEEEECCCCCCHHHEEEEEEECCCEEEECCCCCHH
HQMNFKWLAESMSRPPEKTLIGENGAVYRLTRETFEKVGEVPHGVLYVDGLGVGDITEEI
HHCCHHHHHHHHCCCCCCEEECCCCCEEEEEHHHHHHHHCCCCCEEEEECCCCCHHHHHH
LADRRHMAEEGLVVITALAGEDPVVEVVSRGFVKAGERLLGEVRRMALEALKNGVREKKP
HHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
LERIRDDIYYPVKKFLKKATGRDPMILPVVIEG
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377 [H]