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The map label for this gene is trpB

Identifier: 55981064

GI number: 55981064

Start: 1040777

End: 1042033

Strand: Reverse

Name: trpB

Synonym: TTHA1095

Alternate gene names: 55981064

Gene position: 1042033-1040777 (Counterclockwise)

Preceding gene: 55981066

Following gene: 55981063

Centisome position: 56.33

GC content: 69.13

Gene sequence:

>1257_bases
ATGGGAGTTGTCTTGGCGCGAGGCGCCTTTAGGGAGCGAAGCATGCTGACCCTACCCGACTTTCCCTTGCCCGACGCGAG
GGGGCGGTTCGGCCCCTACGGGGGGCGGTACGTGCCCGAGACCCTAATCCCCGCCCTGGAGGAGTTGGAGGCCGCCTACC
GGGAGGCCAAGAAGGATCCGGCCTTCCTGGAGGAGCTGGACCACTACCTCAGGCAGTTCGCCGGCAGGCCCACGCCCCTT
TACCACGCCAAGCGGCTTTCCGAGTACTGGGGTGGGGCCCAGGTCTTCCTCAAGCGGGAGGACCTCCTCCACACCGGGGC
CCACAAGATCAACAACACCCTGGGCCAGGCCCTCCTGGCGAGGCGCATGGGCAAGAGGCGGGTCATCGCCGAAACGGGGG
CGGGGCAGCACGGGGTGAGCGTGGCCACGGTGGCGGCCCTCTTCGGCCTGGAGTGCGTGGTCTACATGGGGGAGGAGGAC
GTCAGGCGCCAGGCCTTAAACGTCTTCCGCATGAAGCTCCTCGGGGCCGAGGTCCGGCCCGTGGCCGCGGGGAGCCGCAC
CCTCAAGGACGCCACCAACGAGGCCATCCGCGACTGGATCACGAACGTGCGCACCACCTTCTACATCCTGGGCTCCGTGG
TGGGCCCCCACCCCTACCCCATGATGGTCCGGGACTTCCAGAGCGTCATCGGGGAGGAGGTGAAGCGGCAAAGCCTGGAG
CTTTTCGGCCGCCTGCCCGACGCCCTCATCGCCGCGGTGGGGGGCGGTTCCAACGCCATCGGCCTCTTCGCCCCCTTCGC
CTACCTGCCTGAGGGCAGGCCCAAGCTCATCGGGGTGGAGGCCGCCGGGGAGGGGCTTTCCACGGGCAGGCACGCCGCGA
GCATCGGGGCGGGGAAGCGGGGGGTGCTGCACGGGAGCTACATGTACCTCCTCTACGACCACGATGGGCAGATCACCCCG
GCCCACTCCGTCTCCGCAGGGCTGGACTACCCCGGGGTGGGGCCGGAGCACAGCTACTACGCCGACGCCGGGGTGGCGGA
GTACGCCAGCGTCACGGACGAGGAGGCCCTCGAGGGCTTCAAGCTCCTGGCGCGGCTTGAGGGCATCATCCCCGCCTTGG
AGTCGGCCCACGCCATCGCCTACGCCGCCAAGGTGGTGCCGGAGATGGACAAGGACCAGGTGGTGGTCATCAACCTCTCC
GGCCGGGGGGACAAGGACGTGACCGAGGTGATGCGCCTTCTGGGAGGGGAGCTGTGA

Upstream 100 bases:

>100_bases
CCATCTGGTCCACCAGGCGGACGAAGCCCTTGTCCAAGACCGGGATCGTGAGAGGCCCTTCCATCCCCCCGAGTTTACCG
GGAGGCCCCTCCGGGGTAGG

Downstream 100 bases:

>100_bases
CCACCCTCGAGGCCTTCGCCAAGGCCCGGTCCGAGGGCCGGGCCGCCCTCATCCCTTACCTCACCGCGGGCTTCCCCAGC
CGGGAGGGCTTTTTGCAGGC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MGVVLARGAFRERSMLTLPDFPLPDARGRFGPYGGRYVPETLIPALEELEAAYREAKKDPAFLEELDHYLRQFAGRPTPL
YHAKRLSEYWGGAQVFLKREDLLHTGAHKINNTLGQALLARRMGKRRVIAETGAGQHGVSVATVAALFGLECVVYMGEED
VRRQALNVFRMKLLGAEVRPVAAGSRTLKDATNEAIRDWITNVRTTFYILGSVVGPHPYPMMVRDFQSVIGEEVKRQSLE
LFGRLPDALIAAVGGGSNAIGLFAPFAYLPEGRPKLIGVEAAGEGLSTGRHAASIGAGKRGVLHGSYMYLLYDHDGQITP
AHSVSAGLDYPGVGPEHSYYADAGVAEYASVTDEEALEGFKLLARLEGIIPALESAHAIAYAAKVVPEMDKDQVVVINLS
GRGDKDVTEVMRLLGGEL

Sequences:

>Translated_418_residues
MGVVLARGAFRERSMLTLPDFPLPDARGRFGPYGGRYVPETLIPALEELEAAYREAKKDPAFLEELDHYLRQFAGRPTPL
YHAKRLSEYWGGAQVFLKREDLLHTGAHKINNTLGQALLARRMGKRRVIAETGAGQHGVSVATVAALFGLECVVYMGEED
VRRQALNVFRMKLLGAEVRPVAAGSRTLKDATNEAIRDWITNVRTTFYILGSVVGPHPYPMMVRDFQSVIGEEVKRQSLE
LFGRLPDALIAAVGGGSNAIGLFAPFAYLPEGRPKLIGVEAAGEGLSTGRHAASIGAGKRGVLHGSYMYLLYDHDGQITP
AHSVSAGLDYPGVGPEHSYYADAGVAEYASVTDEEALEGFKLLARLEGIIPALESAHAIAYAAKVVPEMDKDQVVVINLS
GRGDKDVTEVMRLLGGEL
>Mature_417_residues
GVVLARGAFRERSMLTLPDFPLPDARGRFGPYGGRYVPETLIPALEELEAAYREAKKDPAFLEELDHYLRQFAGRPTPLY
HAKRLSEYWGGAQVFLKREDLLHTGAHKINNTLGQALLARRMGKRRVIAETGAGQHGVSVATVAALFGLECVVYMGEEDV
RRQALNVFRMKLLGAEVRPVAAGSRTLKDATNEAIRDWITNVRTTFYILGSVVGPHPYPMMVRDFQSVIGEEVKRQSLEL
FGRLPDALIAAVGGGSNAIGLFAPFAYLPEGRPKLIGVEAAGEGLSTGRHAASIGAGKRGVLHGSYMYLLYDHDGQITPA
HSVSAGLDYPGVGPEHSYYADAGVAEYASVTDEEALEGFKLLARLEGIIPALESAHAIAYAAKVVPEMDKDQVVVINLSG
RGDKDVTEVMRLLGGEL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family

Homologues:

Organism=Escherichia coli, GI1787515, Length=386, Percent_Identity=55.699481865285, Blast_Score=429, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6321412, Length=387, Percent_Identity=57.6227390180879, Blast_Score=461, Evalue=1e-130,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPB_THET8 (Q5SJB9)

Other databases:

- EMBL:   AP008226
- RefSeq:   YP_144361.1
- HSSP:   P0A2K1
- ProteinModelPortal:   Q5SJB9
- SMR:   Q5SJB9
- STRING:   Q5SJB9
- GeneID:   3168938
- GenomeReviews:   AP008226_GR
- KEGG:   ttj:TTHA1095
- eggNOG:   COG0133
- HOGENOM:   HBG303148
- OMA:   LKREDLC
- ProtClustDB:   PRK04346
- BioCyc:   TTHE300852:TTHA1095-MONOMER
- HAMAP:   MF_00133
- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026
- TIGRFAMs:   TIGR00263

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.2.1.20

Molecular weight: Translated: 45341; Mature: 45209

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVVLARGAFRERSMLTLPDFPLPDARGRFGPYGGRYVPETLIPALEELEAAYREAKKDP
CCEEECCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCH
AFLEELDHYLRQFAGRPTPLYHAKRLSEYWGGAQVFLKREDLLHTGAHKINNTLGQALLA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
RRMGKRRVIAETGAGQHGVSVATVAALFGLECVVYMGEEDVRRQALNVFRMKLLGAEVRP
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHCCCCCC
VAAGSRTLKDATNEAIRDWITNVRTTFYILGSVVGPHPYPMMVRDFQSVIGEEVKRQSLE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
LFGRLPDALIAAVGGGSNAIGLFAPFAYLPEGRPKLIGVEAAGEGLSTGRHAASIGAGKR
HHHCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHCCCCCC
GVLHGSYMYLLYDHDGQITPAHSVSAGLDYPGVGPEHSYYADAGVAEYASVTDEEALEGF
CEEECEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHH
KLLARLEGIIPALESAHAIAYAAKVVPEMDKDQVVVINLSGRGDKDVTEVMRLLGGEL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
GVVLARGAFRERSMLTLPDFPLPDARGRFGPYGGRYVPETLIPALEELEAAYREAKKDP
CEEECCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCH
AFLEELDHYLRQFAGRPTPLYHAKRLSEYWGGAQVFLKREDLLHTGAHKINNTLGQALLA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
RRMGKRRVIAETGAGQHGVSVATVAALFGLECVVYMGEEDVRRQALNVFRMKLLGAEVRP
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHCCCCCC
VAAGSRTLKDATNEAIRDWITNVRTTFYILGSVVGPHPYPMMVRDFQSVIGEEVKRQSLE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
LFGRLPDALIAAVGGGSNAIGLFAPFAYLPEGRPKLIGVEAAGEGLSTGRHAASIGAGKR
HHHCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHCCCCCC
GVLHGSYMYLLYDHDGQITPAHSVSAGLDYPGVGPEHSYYADAGVAEYASVTDEEALEGF
CEEECEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHH
KLLARLEGIIPALESAHAIAYAAKVVPEMDKDQVVVINLSGRGDKDVTEVMRLLGGEL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA