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The map label for this gene is rho [H]

Identifier: 55981034

GI number: 55981034

Start: 1011662

End: 1012942

Strand: Reverse

Name: rho [H]

Synonym: TTHA1065

Alternate gene names: 55981034

Gene position: 1012942-1011662 (Counterclockwise)

Preceding gene: 55981035

Following gene: 55981033

Centisome position: 54.76

GC content: 67.21

Gene sequence:

>1281_bases
ATGAGAAGGAAGGAAACCCTTCAGGAAACTCCCCTCACCTACCAGGAGCTCGCCAGCAAGATCCTGCCCGAGCTCCACCT
CCTGGCCCAGGAGGCGGGCATTGAAGGCTACAAGCGCATGAAGAAGGACCAGCTCATCATGGCCCTCCTGGAGCGGCAGA
CCCAGGGAGAGGGGCTGAGGCTGGTCAAGGGCTACCTGGAGATCAGCCAGGACGGGTACGGCTTCCTCACCGAGAACCTC
CACAACCTGGAGTCCCGGGTGGCCATCGTCTCGGCGGGGCTCATCAAGCAGTACGCCCTGAGGGCCGGGGACTACGTGGT
GGGCCAGGCCAGGCCGCCCCGGGAGAACGAGCGCTACGCCACCCTCCTCAAGGTGGAGGCGGTGAACAACCTGGACCCCG
AGGCCGCCAAGAACCGCCCCCGCTTTGACGAGCTCACCCCCCAGTTCCCCGACCGGCAGATCCGGTTGGAGACCACCCCG
GACGAGCTCTCCACCCGGGTCATTGACCTCCTCGCCCCCATCGGCCGGGGCCAGCGCGGCCTCATCGTGGCCCCTCCCAA
GGCGGGGAAGACCACCCTCCTCAAGAAGATCGCCAACGCCGTCCTCAAGAACGAGCCCGACATCAAGGTCATCGTCCTCC
TCATTGACGAGCGCCCCGAGGAGGTCACGGACTTCCGGGAGAGCGTCCAAGGCGCCGAGGTCATCGCCAGCACCTTTGAC
GAGCCTCCCCAGAACCACATCCGCGTGGCCGAGTTCGTCCACGAGAGGGCCAAGCGCATCGTGGAGGAGGGCGGGCACGT
GATGATCCTCCTGGACTCCATCACCCGCCTGGCCCGGGCGAACAACCTGGTGACCCCGCCCACGGGGCGCACCCTCTCGG
GCGGTCTGGACTCCGCCGCCCTCTACTTCCCCAAGCGCTTCCTGGGGGCGGCCCGGAACATCCGTGGGGGCGGGAGCCTC
ACCATCCTCGCCACCGCCCTCGTGGAGACGGGCAGCCGCATGGACGACGTGATCTTTGAGGAGTTCAAGGGGACGGGCAA
CATGGAGCTCCACCTCTCCCGCCGCCTGGAGGAGCGGCGCATCTTCCCCGCCATCGACATCCTCAAGTCCGGCACGAGGC
GGGAGGAGTTGCTCCTCGGCGAGGAGGTCACCCACAAGATGTGGCTCCTGCGCAAGGTCCTGGCGGACATGGACCCCGCG
GAGGCCATGGAGATGCTCCTCGCCCGGCTCGCCCGCACCAAGAACAACAAGGAGTTCCTGGCCTCCCTGGCCGCCCGCTG
A

Upstream 100 bases:

>100_bases
TCGCCACCATGCCCCACGCCGTTTTCAAGCAGCTCCTAAAGCACCCCCTCACGGACATCGGCCTTAAGCGCTTCTTGGAG
GATTGGGAGAAGGTTAAGCC

Downstream 100 bases:

>100_bases
CCCCTTTGGGTTTCCGCGGAACCCCTCTGCCGGGGCCTCCCTGGGGGCTTGGGCTCCCGGCGGGTGGTATGCTAAGGCCA
GGTGCTTCGGCACCTCCTTC

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MRRKETLQETPLTYQELASKILPELHLLAQEAGIEGYKRMKKDQLIMALLERQTQGEGLRLVKGYLEISQDGYGFLTENL
HNLESRVAIVSAGLIKQYALRAGDYVVGQARPPRENERYATLLKVEAVNNLDPEAAKNRPRFDELTPQFPDRQIRLETTP
DELSTRVIDLLAPIGRGQRGLIVAPPKAGKTTLLKKIANAVLKNEPDIKVIVLLIDERPEEVTDFRESVQGAEVIASTFD
EPPQNHIRVAEFVHERAKRIVEEGGHVMILLDSITRLARANNLVTPPTGRTLSGGLDSAALYFPKRFLGAARNIRGGGSL
TILATALVETGSRMDDVIFEEFKGTGNMELHLSRRLEERRIFPAIDILKSGTRREELLLGEEVTHKMWLLRKVLADMDPA
EAMEMLLARLARTKNNKEFLASLAAR

Sequences:

>Translated_426_residues
MRRKETLQETPLTYQELASKILPELHLLAQEAGIEGYKRMKKDQLIMALLERQTQGEGLRLVKGYLEISQDGYGFLTENL
HNLESRVAIVSAGLIKQYALRAGDYVVGQARPPRENERYATLLKVEAVNNLDPEAAKNRPRFDELTPQFPDRQIRLETTP
DELSTRVIDLLAPIGRGQRGLIVAPPKAGKTTLLKKIANAVLKNEPDIKVIVLLIDERPEEVTDFRESVQGAEVIASTFD
EPPQNHIRVAEFVHERAKRIVEEGGHVMILLDSITRLARANNLVTPPTGRTLSGGLDSAALYFPKRFLGAARNIRGGGSL
TILATALVETGSRMDDVIFEEFKGTGNMELHLSRRLEERRIFPAIDILKSGTRREELLLGEEVTHKMWLLRKVLADMDPA
EAMEMLLARLARTKNNKEFLASLAAR
>Mature_426_residues
MRRKETLQETPLTYQELASKILPELHLLAQEAGIEGYKRMKKDQLIMALLERQTQGEGLRLVKGYLEISQDGYGFLTENL
HNLESRVAIVSAGLIKQYALRAGDYVVGQARPPRENERYATLLKVEAVNNLDPEAAKNRPRFDELTPQFPDRQIRLETTP
DELSTRVIDLLAPIGRGQRGLIVAPPKAGKTTLLKKIANAVLKNEPDIKVIVLLIDERPEEVTDFRESVQGAEVIASTFD
EPPQNHIRVAEFVHERAKRIVEEGGHVMILLDSITRLARANNLVTPPTGRTLSGGLDSAALYFPKRFLGAARNIRGGGSL
TILATALVETGSRMDDVIFEEFKGTGNMELHLSRRLEERRIFPAIDILKSGTRREELLLGEEVTHKMWLLRKVLADMDPA
EAMEMLLARLARTKNNKEFLASLAAR

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=414, Percent_Identity=52.1739130434783, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI1788251, Length=265, Percent_Identity=31.6981132075472, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 47774; Mature: 47774

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRKETLQETPLTYQELASKILPELHLLAQEAGIEGYKRMKKDQLIMALLERQTQGEGLR
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCHH
LVKGYLEISQDGYGFLTENLHNLESRVAIVSAGLIKQYALRAGDYVVGQARPPRENERYA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHH
TLLKVEAVNNLDPEAAKNRPRFDELTPQFPDRQIRLETTPDELSTRVIDLLAPIGRGQRG
HHEEEEHHCCCCCHHHCCCCCCHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCC
LIVAPPKAGKTTLLKKIANAVLKNEPDIKVIVLLIDERPEEVTDFRESVQGAEVIASTFD
EEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCC
EPPQNHIRVAEFVHERAKRIVEEGGHVMILLDSITRLARANNLVTPPTGRTLSGGLDSAA
CCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
LYFPKRFLGAARNIRGGGSLTILATALVETGSRMDDVIFEEFKGTGNMELHLSRRLEERR
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHH
IFPAIDILKSGTRREELLLGEEVTHKMWLLRKVLADMDPAEAMEMLLARLARTKNNKEFL
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
ASLAAR
HHHHCC
>Mature Secondary Structure
MRRKETLQETPLTYQELASKILPELHLLAQEAGIEGYKRMKKDQLIMALLERQTQGEGLR
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCHH
LVKGYLEISQDGYGFLTENLHNLESRVAIVSAGLIKQYALRAGDYVVGQARPPRENERYA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHH
TLLKVEAVNNLDPEAAKNRPRFDELTPQFPDRQIRLETTPDELSTRVIDLLAPIGRGQRG
HHEEEEHHCCCCCHHHCCCCCCHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCC
LIVAPPKAGKTTLLKKIANAVLKNEPDIKVIVLLIDERPEEVTDFRESVQGAEVIASTFD
EEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCC
EPPQNHIRVAEFVHERAKRIVEEGGHVMILLDSITRLARANNLVTPPTGRTLSGGLDSAA
CCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
LYFPKRFLGAARNIRGGGSLTILATALVETGSRMDDVIFEEFKGTGNMELHLSRRLEERR
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHH
IFPAIDILKSGTRREELLLGEEVTHKMWLLRKVLADMDPAEAMEMLLARLARTKNNKEFL
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
ASLAAR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8051015; 10567266 [H]