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The map label for this gene is livF [H]

Identifier: 55980933

GI number: 55980933

Start: 909629

End: 909907

Strand: Direct

Name: livF [H]

Synonym: TTHA0964

Alternate gene names: 55980933

Gene position: 909629-909907 (Clockwise)

Preceding gene: 55980932

Following gene: 55980934

Centisome position: 49.18

GC content: 71.68

Gene sequence:

>279_bases
ATGGCCAGGCCCCGCCTCCTCCTCCTGGACGAGCCTTCCTTGGGCCTCGCGCCCCTCATCGTCCAGGAGATCTTCCGCAC
CCTGGCCGCCCTCAAGGGGGAGGGGGTGACCCTCCTCCTCGTGGAGCAGAACGCCAAGATGGCCCTTTCCCTGGCGGACC
GGGGGGTGGTCCTGGAGGCGGGGGAGGTGGCCCTTTCGGGGCGGGCCGAGGAGCTTAGGGCAAACCCCCGGGTGGTGGAG
GCCTACCTGGGGGCGGCGCGGGAGGTGGAAGGGGGATGA

Upstream 100 bases:

>100_bases
GCGTCCTCCTCGTGGACCACGACATGGACCTCGTCATGGGGCTCGCCGACCGGGTGGTGGTGATGAACTACGGGGAGAGC
TCGCCATCGGTCGGGCCCTC

Downstream 100 bases:

>100_bases
GGGACCCCTTCATGGAGGCCTTGGGCCTAAAGGTCCTCCACCTCGCCCCGGGGGAAGCGGTGGTGGCGGGGGAGGTGCGG
GCGGACCACTTAAACCTCCA

Product: ABC transporter ATP-binding protein

Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein F [H]

Number of amino acids: Translated: 92; Mature: 91

Protein sequence:

>92_residues
MARPRLLLLDEPSLGLAPLIVQEIFRTLAALKGEGVTLLLVEQNAKMALSLADRGVVLEAGEVALSGRAEELRANPRVVE
AYLGAAREVEGG

Sequences:

>Translated_92_residues
MARPRLLLLDEPSLGLAPLIVQEIFRTLAALKGEGVTLLLVEQNAKMALSLADRGVVLEAGEVALSGRAEELRANPRVVE
AYLGAAREVEGG
>Mature_91_residues
ARPRLLLLDEPSLGLAPLIVQEIFRTLAALKGEGVTLLLVEQNAKMALSLADRGVVLEAGEVALSGRAEELRANPRVVEA
YLGAAREVEGG

Specific function: Component of the leucine-specific transport system [H]

COG id: COG0410

COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI87082268, Length=84, Percent_Identity=61.9047619047619, Blast_Score=103, Evalue=3e-24,
Organism=Escherichia coli, GI1789864, Length=87, Percent_Identity=36.7816091954023, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 9748; Mature: 9616

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPRLLLLDEPSLGLAPLIVQEIFRTLAALKGEGVTLLLVEQNAKMALSLADRGVVLEA
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCEEEEC
GEVALSGRAEELRANPRVVEAYLGAAREVEGG
CCEEECCCHHHHHCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ARPRLLLLDEPSLGLAPLIVQEIFRTLAALKGEGVTLLLVEQNAKMALSLADRGVVLEA
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCEEEEC
GEVALSGRAEELRANPRVVEAYLGAAREVEGG
CCEEECCCHHHHHCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]