Click here to switch to the map view.

The map label for this gene is asnC [H]

Identifier: 55980677

GI number: 55980677

Start: 671830

End: 673146

Strand: Reverse

Name: asnC [H]

Synonym: TTHA0708

Alternate gene names: 55980677

Gene position: 673146-671830 (Counterclockwise)

Preceding gene: 55980678

Following gene: 55980671

Centisome position: 36.39

GC content: 68.49

Gene sequence:

>1317_bases
ATGCGCGTCTTCATTGACGAGATCGCCCGCCACGTGGACCAGGAGGTGGAGCTCAGGGGCTGGCTCTACCAGAGGCGCTC
CAAGGGCAAGATCCACTTCCTCATCCTCCGGGACGGCACCGGCTTCCTCCAGGCCACGGTGGTCCAGGGGGAGGTGCCGG
AAGCGGTCTTCCGGGAAGCGGACCACCTCCCCCAGGAAACCGCCCTAAGGGTGTGGGGCCGGGTGCGGGAGGACCGGAGG
GCCCCGGGGGGGTTTGAGCTCGCCGTGCGGGACCTTCAGGTGGTGAGCCGCCCCCAGGGGGAGTACCCCATCGGCCCCAA
GGAGCACGGCATAGACTTCCTCATGGACCACCGCCACCTCTGGCTCCGCCACCGCCGCCCCTTCGCCGTGATGCGCATCC
GGGACGAGCTGGAAAGGGCCATCCACGAGTTCTTCGGAGAGCGGGGCTTCCTCCGCTTTGACGCCCCCATCCTCACCCCA
AGCGCCGTGGAGGGGACCACGGAGCTCTTTGAGGTGGAGCTCTTTGACGGGGAGAAGGCCTACCTCTCCCAGTCGGGGCA
GCTTTACGCCGAGGCCGGGGCCCTGGCCTTCGCCAAGGTCTACACCTTCGGCCCCACCTTCCGGGCGGAGCGCTCCAAGA
CGCGGCGCCACCTCCTGGAGTTCTGGATGGTGGAGCCCGAGGTGGCCTTCATGACCCACGAGGAGAACATGGCCCTCCAG
GAGGAGCTCGTGAGCTTCCTCGTGGCCAGGGTGCTGGAAAGGCGCTCTCGGGAGCTTGAGATGCTCGGGCGGGACCCCAA
GGCCCTGGAGCCCGCCGCGGAGGGCCACTACCCCAGGCTCACCTACAAGGAGGCCGTGGCCCTGGTGAACCGGATCGCCC
AAGAGGACCCCGAGGTCCCTCCCCTCCCCTACGGCGAGGACTTCGGGGCCCCCCACGAGGCCGCCTTAAGCCGCCGGTTT
GACCGCCCCGTCTTCGTGGAGCGCTACCCCGCCCGGATCAAGGCCTTCTACATGGAGCCGGACCCCGAAGACCCCGAGCT
CGTCCTGAACGACGACCTCCTCGCCCCCGAGGGCTACGGGGAGATCATCGGGGGAAGCCAGAGGATCCACGACCTGGAGC
TTCTAAGGCGCAAGATCCAGGAGTTCGGCCTCCCGGAGGAGGTCTACGACTGGTACCTGGACCTCCGCCGCTTCGGGAGC
GTCCCCCACTCGGGGTTCGGCCTGGGCCTGGAGCGGACCGTGGCCTGGATCTGCGGGCTAGCCCACGTGCGGGAGGCCAT
CCCCTTCCCGAGGATGTACACGAGGATGCGCCCCTAA

Upstream 100 bases:

>100_bases
CGGCCTGGCCGAGGCCCTCCGCCTCCTCAGGGGATAGGAAAGGCCCTCACGGAAGGCCCAAGGGGATAAACGCCCGGTAA
ACGCGTAGACTGGGAGGGGT

Downstream 100 bases:

>100_bases
GCCCGCGTTTTCGCAACGTGGGAGGCCTGAAATAAGGCTTGGAAAGTCCCTTTTGGGGCCCCGTGGGGTACTTAAACCCC
GGCGAGCTCCAGGAAGTAGC

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MRVFIDEIARHVDQEVELRGWLYQRRSKGKIHFLILRDGTGFLQATVVQGEVPEAVFREADHLPQETALRVWGRVREDRR
APGGFELAVRDLQVVSRPQGEYPIGPKEHGIDFLMDHRHLWLRHRRPFAVMRIRDELERAIHEFFGERGFLRFDAPILTP
SAVEGTTELFEVELFDGEKAYLSQSGQLYAEAGALAFAKVYTFGPTFRAERSKTRRHLLEFWMVEPEVAFMTHEENMALQ
EELVSFLVARVLERRSRELEMLGRDPKALEPAAEGHYPRLTYKEAVALVNRIAQEDPEVPPLPYGEDFGAPHEAALSRRF
DRPVFVERYPARIKAFYMEPDPEDPELVLNDDLLAPEGYGEIIGGSQRIHDLELLRRKIQEFGLPEEVYDWYLDLRRFGS
VPHSGFGLGLERTVAWICGLAHVREAIPFPRMYTRMRP

Sequences:

>Translated_438_residues
MRVFIDEIARHVDQEVELRGWLYQRRSKGKIHFLILRDGTGFLQATVVQGEVPEAVFREADHLPQETALRVWGRVREDRR
APGGFELAVRDLQVVSRPQGEYPIGPKEHGIDFLMDHRHLWLRHRRPFAVMRIRDELERAIHEFFGERGFLRFDAPILTP
SAVEGTTELFEVELFDGEKAYLSQSGQLYAEAGALAFAKVYTFGPTFRAERSKTRRHLLEFWMVEPEVAFMTHEENMALQ
EELVSFLVARVLERRSRELEMLGRDPKALEPAAEGHYPRLTYKEAVALVNRIAQEDPEVPPLPYGEDFGAPHEAALSRRF
DRPVFVERYPARIKAFYMEPDPEDPELVLNDDLLAPEGYGEIIGGSQRIHDLELLRRKIQEFGLPEEVYDWYLDLRRFGS
VPHSGFGLGLERTVAWICGLAHVREAIPFPRMYTRMRP
>Mature_438_residues
MRVFIDEIARHVDQEVELRGWLYQRRSKGKIHFLILRDGTGFLQATVVQGEVPEAVFREADHLPQETALRVWGRVREDRR
APGGFELAVRDLQVVSRPQGEYPIGPKEHGIDFLMDHRHLWLRHRRPFAVMRIRDELERAIHEFFGERGFLRFDAPILTP
SAVEGTTELFEVELFDGEKAYLSQSGQLYAEAGALAFAKVYTFGPTFRAERSKTRRHLLEFWMVEPEVAFMTHEENMALQ
EELVSFLVARVLERRSRELEMLGRDPKALEPAAEGHYPRLTYKEAVALVNRIAQEDPEVPPLPYGEDFGAPHEAALSRRF
DRPVFVERYPARIKAFYMEPDPEDPELVLNDDLLAPEGYGEIIGGSQRIHDLELLRRKIQEFGLPEEVYDWYLDLRRFGS
VPHSGFGLGLERTVAWICGLAHVREAIPFPRMYTRMRP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=438, Percent_Identity=34.2465753424658, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI4758762, Length=431, Percent_Identity=32.4825986078886, Blast_Score=232, Evalue=7e-61,
Organism=Homo sapiens, GI45439306, Length=468, Percent_Identity=30.3418803418803, Blast_Score=175, Evalue=7e-44,
Organism=Escherichia coli, GI1787161, Length=454, Percent_Identity=39.8678414096916, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI1788173, Length=288, Percent_Identity=26.7361111111111, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71984122, Length=446, Percent_Identity=35.8744394618834, Blast_Score=261, Evalue=5e-70,
Organism=Caenorhabditis elegans, GI17551876, Length=460, Percent_Identity=28.4782608695652, Blast_Score=156, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17556372, Length=365, Percent_Identity=34.5205479452055, Blast_Score=155, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6321807, Length=437, Percent_Identity=35.2402745995423, Blast_Score=258, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6319872, Length=459, Percent_Identity=30.0653594771242, Blast_Score=183, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6323011, Length=471, Percent_Identity=29.2993630573248, Blast_Score=162, Evalue=9e-41,
Organism=Drosophila melanogaster, GI19921528, Length=448, Percent_Identity=34.5982142857143, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI19922416, Length=444, Percent_Identity=31.7567567567568, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI17136276, Length=455, Percent_Identity=29.010989010989, Blast_Score=170, Evalue=1e-42,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 50786; Mature: 50786

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVFIDEIARHVDQEVELRGWLYQRRSKGKIHFLILRDGTGFLQATVVQGEVPEAVFREA
CEEHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHH
DHLPQETALRVWGRVREDRRAPGGFELAVRDLQVVSRPQGEYPIGPKEHGIDFLMDHRHL
HCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
WLRHRRPFAVMRIRDELERAIHEFFGERGFLRFDAPILTPSAVEGTTELFEVELFDGEKA
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEEEEEECCCHH
YLSQSGQLYAEAGALAFAKVYTFGPTFRAERSKTRRHLLEFWMVEPEVAFMTHEENMALQ
HHCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHH
EELVSFLVARVLERRSRELEMLGRDPKALEPAAEGHYPRLTYKEAVALVNRIAQEDPEVP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
PLPYGEDFGAPHEAALSRRFDRPVFVERYPARIKAFYMEPDPEDPELVLNDDLLAPEGYG
CCCCCCCCCCCHHHHHHHHCCCCCHHHCCCCEEEEEEECCCCCCCCEEECCCCCCCCCCC
EIIGGSQRIHDLELLRRKIQEFGLPEEVYDWYLDLRRFGSVPHSGFGLGLERTVAWICGL
HHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
AHVREAIPFPRMYTRMRP
HHHHHHCCCCHHHHCCCC
>Mature Secondary Structure
MRVFIDEIARHVDQEVELRGWLYQRRSKGKIHFLILRDGTGFLQATVVQGEVPEAVFREA
CEEHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHH
DHLPQETALRVWGRVREDRRAPGGFELAVRDLQVVSRPQGEYPIGPKEHGIDFLMDHRHL
HCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
WLRHRRPFAVMRIRDELERAIHEFFGERGFLRFDAPILTPSAVEGTTELFEVELFDGEKA
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEEEEEECCCHH
YLSQSGQLYAEAGALAFAKVYTFGPTFRAERSKTRRHLLEFWMVEPEVAFMTHEENMALQ
HHCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHH
EELVSFLVARVLERRSRELEMLGRDPKALEPAAEGHYPRLTYKEAVALVNRIAQEDPEVP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
PLPYGEDFGAPHEAALSRRFDRPVFVERYPARIKAFYMEPDPEDPELVLNDDLLAPEGYG
CCCCCCCCCCCHHHHHHHHCCCCCHHHCCCCEEEEEEECCCCCCCCEEECCCCCCCCCCC
EIIGGSQRIHDLELLRRKIQEFGLPEEVYDWYLDLRRFGSVPHSGFGLGLERTVAWICGL
HHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
AHVREAIPFPRMYTRMRP
HHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA