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The map label for this gene is mrp [H]

Identifier: 55980623

GI number: 55980623

Start: 621300

End: 622352

Strand: Direct

Name: mrp [H]

Synonym: TTHA0654

Alternate gene names: 55980623

Gene position: 621300-622352 (Clockwise)

Preceding gene: 55980621

Following gene: 55980624

Centisome position: 33.59

GC content: 71.6

Gene sequence:

>1053_bases
ATGGCGCTTACGGAAGAGCGGGTCCTCGAGGCCCTGCGCACCGTGATGGACCCCGAGCTCGGCAAGGACCTCGTCTCCTT
GGGCATGGTGGACGAGGTCCGGGTGGAGGGGGGGCGGGTGGACCTCCTGGTGAACCTCACCACCCCGGCCTGCCCCCTCA
AGGGGCAGATTGAGGCGGACATCCGGCGGGCCCTCGCCCCCTTGGGGGCGGAGGAGGTCCGGGTGCGCTTCGGCGGGGGC
GTGCGCCCCCCTGAGCGCTACGCCCTCCCCGGGGTCAAGCACGTGGTGGCCGTGGCCTCGGGCAAGGGCGGGGTGGGGAA
GAGCACCGTGGCCGCCAACCTGGCCCTGGCCTTAAGCCGGGAAGGGGCCAAGGTGGGCCTTTTGGACGCCGACCTCTACG
GGCCGAGCCAGGCGAAGATGTTCGGCCTCGAGGGCATGCGCCTCAAGGTGGACCAGGACCGCAGGATCCTCCCCTTGGAG
GCCCACGGGATCAAGGTCCTCTCCATCGCCAACATCGTCCCCCCGGGGCAGGCCCTGGCCTGGCGGGGGCCCATCCTCCA
CGGCACCCTGAAGCAGTTCCTGCAGGACGTGAACTGGGGGGAGCTGGACTACCTGGTGGTGGACCTTCCCCCGGGGACGG
GGGACGTGCAGCTCAGCCTTTCCCAGCTCACCCAGGTCTCGGGCGGGGTCATCGTCACCACGCCCCAGGAGGTGGCCCTC
ATTGACGCCGAGCGGGCGGCGGACATGTTCCGGAAGCTCCAGGTCCCGGTCCTCGGCGTCCTGGAGAACATGAGCGCCTT
CCTCTGCCCCCACTGCGGCAAGCCCACCCCCATCTTCGGGGAGGGGGGCGGGAGGCGCCTGGCGGAGAGGCTCAAGACCC
GCTTCCTGGGGGAGATCCCCCTCACCCTGGCCTTGCGGGAGAGCGGGGACCGGGGCGTGCCCGTCCTGGCGCAGGACCCC
GAGGGCCTCGAGGCCCAGGCCTTCCTGAAGGCGGCCCGGGAGCTCGCCGCCGCCTTGAGCGTGCAGACCTTCCTCCCCCT
CCCCATGGCCTGA

Upstream 100 bases:

>100_bases
GCGCCGCTTGCGCCACTCGGGGTACACGAGACGAGTATACCCGGCCTTTGTGCCTTTCGCCCTTGCCCAAAACTATCCTG
GGGTATACTCTAGGCCCGGT

Downstream 100 bases:

>100_bases
ACCATGGTCCTCCTGGAAGGCACCAAGGAACGGGTTCTGGAGCTCCTTAGGGCCAGGCCCCGCACCGCCAAGGAGGTGGC
GGAAGCCTTGGGGGTGAGCC

Product: ATP-binding Mrp/Nbp35 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MALTEERVLEALRTVMDPELGKDLVSLGMVDEVRVEGGRVDLLVNLTTPACPLKGQIEADIRRALAPLGAEEVRVRFGGG
VRPPERYALPGVKHVVAVASGKGGVGKSTVAANLALALSREGAKVGLLDADLYGPSQAKMFGLEGMRLKVDQDRRILPLE
AHGIKVLSIANIVPPGQALAWRGPILHGTLKQFLQDVNWGELDYLVVDLPPGTGDVQLSLSQLTQVSGGVIVTTPQEVAL
IDAERAADMFRKLQVPVLGVLENMSAFLCPHCGKPTPIFGEGGGRRLAERLKTRFLGEIPLTLALRESGDRGVPVLAQDP
EGLEAQAFLKAARELAAALSVQTFLPLPMA

Sequences:

>Translated_350_residues
MALTEERVLEALRTVMDPELGKDLVSLGMVDEVRVEGGRVDLLVNLTTPACPLKGQIEADIRRALAPLGAEEVRVRFGGG
VRPPERYALPGVKHVVAVASGKGGVGKSTVAANLALALSREGAKVGLLDADLYGPSQAKMFGLEGMRLKVDQDRRILPLE
AHGIKVLSIANIVPPGQALAWRGPILHGTLKQFLQDVNWGELDYLVVDLPPGTGDVQLSLSQLTQVSGGVIVTTPQEVAL
IDAERAADMFRKLQVPVLGVLENMSAFLCPHCGKPTPIFGEGGGRRLAERLKTRFLGEIPLTLALRESGDRGVPVLAQDP
EGLEAQAFLKAARELAAALSVQTFLPLPMA
>Mature_349_residues
ALTEERVLEALRTVMDPELGKDLVSLGMVDEVRVEGGRVDLLVNLTTPACPLKGQIEADIRRALAPLGAEEVRVRFGGGV
RPPERYALPGVKHVVAVASGKGGVGKSTVAANLALALSREGAKVGLLDADLYGPSQAKMFGLEGMRLKVDQDRRILPLEA
HGIKVLSIANIVPPGQALAWRGPILHGTLKQFLQDVNWGELDYLVVDLPPGTGDVQLSLSQLTQVSGGVIVTTPQEVALI
DAERAADMFRKLQVPVLGVLENMSAFLCPHCGKPTPIFGEGGGRRLAERLKTRFLGEIPLTLALRESGDRGVPVLAQDPE
GLEAQAFLKAARELAAALSVQTFLPLPMA

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=294, Percent_Identity=45.9183673469388, Blast_Score=242, Evalue=5e-64,
Organism=Homo sapiens, GI6912540, Length=239, Percent_Identity=43.9330543933054, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI118572611, Length=244, Percent_Identity=40.5737704918033, Blast_Score=183, Evalue=2e-46,
Organism=Escherichia coli, GI87082045, Length=294, Percent_Identity=45.578231292517, Blast_Score=254, Evalue=8e-69,
Organism=Caenorhabditis elegans, GI25143050, Length=256, Percent_Identity=39.0625, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6322188, Length=222, Percent_Identity=42.7927927927928, Blast_Score=196, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6321347, Length=258, Percent_Identity=38.3720930232558, Blast_Score=172, Evalue=5e-44,
Organism=Drosophila melanogaster, GI221511043, Length=259, Percent_Identity=36.6795366795367, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24667611, Length=258, Percent_Identity=40.3100775193798, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI19921440, Length=237, Percent_Identity=36.7088607594937, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR002744
- InterPro:   IPR000808 [H]

Pfam domain/function: PF01883 DUF59; PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 37263; Mature: 37132

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTEERVLEALRTVMDPELGKDLVSLGMVDEVRVEGGRVDLLVNLTTPACPLKGQIEAD
CCCCHHHHHHHHHHHHCHHHHHHHHHHCCHHHEEECCCEEEEEEEECCCCCCCCCCHHHH
IRRALAPLGAEEVRVRFGGGVRPPERYALPGVKHVVAVASGKGGVGKSTVAANLALALSR
HHHHHCCCCHHHEEEEECCCCCCCHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHEEEEC
EGAKVGLLDADLYGPSQAKMFGLEGMRLKVDQDRRILPLEAHGIKVLSIANIVPPGQALA
CCCEEEEEECCCCCCCCCEEECCCCEEEEECCCCCEEEEECCCEEEEEEECCCCCCCCEE
WRGPILHGTLKQFLQDVNWGELDYLVVDLPPGTGDVQLSLSQLTQVSGGVIVTTPQEVAL
ECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEHHHHHHHCCCEEEECCCCEEE
IDAERAADMFRKLQVPVLGVLENMSAFLCPHCGKPTPIFGEGGGRRLAERLKTRFLGEIP
EEHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHCCCCC
LTLALRESGDRGVPVLAQDPEGLEAQAFLKAARELAAALSVQTFLPLPMA
EEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ALTEERVLEALRTVMDPELGKDLVSLGMVDEVRVEGGRVDLLVNLTTPACPLKGQIEAD
CCCHHHHHHHHHHHHCHHHHHHHHHHCCHHHEEECCCEEEEEEEECCCCCCCCCCHHHH
IRRALAPLGAEEVRVRFGGGVRPPERYALPGVKHVVAVASGKGGVGKSTVAANLALALSR
HHHHHCCCCHHHEEEEECCCCCCCHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHEEEEC
EGAKVGLLDADLYGPSQAKMFGLEGMRLKVDQDRRILPLEAHGIKVLSIANIVPPGQALA
CCCEEEEEECCCCCCCCCEEECCCCEEEEECCCCCEEEEECCCEEEEEEECCCCCCCCEE
WRGPILHGTLKQFLQDVNWGELDYLVVDLPPGTGDVQLSLSQLTQVSGGVIVTTPQEVAL
ECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEHHHHHHHCCCEEEECCCCEEE
IDAERAADMFRKLQVPVLGVLENMSAFLCPHCGKPTPIFGEGGGRRLAERLKTRFLGEIP
EEHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHCCCCC
LTLALRESGDRGVPVLAQDPEGLEAQAFLKAARELAAALSVQTFLPLPMA
EEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]