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The map label for this gene is infC

Identifier: 55980520

GI number: 55980520

Start: 514382

End: 514816

Strand: Direct

Name: infC

Synonym: TTHA0551

Alternate gene names: 55980520

Gene position: 514382-514816 (Clockwise)

Preceding gene: 55980517

Following gene: 55980521

Centisome position: 27.81

GC content: 63.91

Gene sequence:

>435_bases
ATGGACACCCGGGAGGCCCTGCGCTTGGCCCAGGAGATGGACCTGGACCTGGTCCTGGTGGGCCCCAACGCCGATCCGCC
CGTGGCCCGGATCATGGACTACTCCAAGTGGCGCTACGAGCAGCAGATGGCGGAGAAGGAGGCCCGGAAGAAGGCCAAGC
GCACCGAGGTCAAGTCCATCAAGTTCCGGGTAAAGATAGACGAGCACGACTATCAGACCAAGCTGGGCCATATCAAGCGC
TTCCTGCAGGAGGGCCACAAGGTCAAGGTGACCATCATGTTCCGGGGACGGGAGGTGGCCCACCCCGAGCTCGGGGAGAG
GATCCTCAACCGCGTGACCGAGGACCTCAAGGACCTCGCCGTGGTGGAGATGAAGCCCGAGATGCTGGGGCGGGACATGA
ACATGCTCCTCGCCCCGGTGAAGGTCTCCGCCTAG

Upstream 100 bases:

>100_bases
GGGCTGGGAGGTGATGTAGATAAAGGAGTACCTGACCAACGAACGCATACGCGCCAAACAGGTTCGCGTCGTCGGTCCCG
ACGGCAAGCAGCTCGGCATC

Downstream 100 bases:

>100_bases
ACCCCGCCCAGGGGCCTCTGGTATAGTGGGGGGGCTTTGGGGAGCACCCAAGACCCCCTTTGTGGGGGCGCTTCCCAGGG
CGGAGGAGGCTTATGCCGAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MDTREALRLAQEMDLDLVLVGPNADPPVARIMDYSKWRYEQQMAEKEARKKAKRTEVKSIKFRVKIDEHDYQTKLGHIKR
FLQEGHKVKVTIMFRGREVAHPELGERILNRVTEDLKDLAVVEMKPEMLGRDMNMLLAPVKVSA

Sequences:

>Translated_144_residues
MDTREALRLAQEMDLDLVLVGPNADPPVARIMDYSKWRYEQQMAEKEARKKAKRTEVKSIKFRVKIDEHDYQTKLGHIKR
FLQEGHKVKVTIMFRGREVAHPELGERILNRVTEDLKDLAVVEMKPEMLGRDMNMLLAPVKVSA
>Mature_144_residues
MDTREALRLAQEMDLDLVLVGPNADPPVARIMDYSKWRYEQQMAEKEARKKAKRTEVKSIKFRVKIDEHDYQTKLGHIKR
FLQEGHKVKVTIMFRGREVAHPELGERILNRVTEDLKDLAVVEMKPEMLGRDMNMLLAPVKVSA

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=139, Percent_Identity=55.3956834532374, Blast_Score=135, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_THET2 (Q9ACJ8)

Other databases:

- EMBL:   AJ409350
- EMBL:   AE017221
- RefSeq:   YP_004158.1
- ProteinModelPortal:   Q9ACJ8
- SMR:   Q9ACJ8
- STRING:   Q9ACJ8
- GeneID:   2774489
- GenomeReviews:   AE017221_GR
- eggNOG:   COG0290
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- PhylomeDB:   Q9ACJ8
- ProtClustDB:   PRK00028
- BioCyc:   TTHE262724:TT_C0183-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 16785; Mature: 16785

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTREALRLAQEMDLDLVLVGPNADPPVARIMDYSKWRYEQQMAEKEARKKAKRTEVKSI
CCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
KFRVKIDEHDYQTKLGHIKRFLQEGHKVKVTIMFRGREVAHPELGERILNRVTEDLKDLA
EEEEEECCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
VVEMKPEMLGRDMNMLLAPVKVSA
HHEECHHHHCCCHHHEEECEEECC
>Mature Secondary Structure
MDTREALRLAQEMDLDLVLVGPNADPPVARIMDYSKWRYEQQMAEKEARKKAKRTEVKSI
CCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
KFRVKIDEHDYQTKLGHIKRFLQEGHKVKVTIMFRGREVAHPELGERILNRVTEDLKDLA
EEEEEECCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
VVEMKPEMLGRDMNMLLAPVKVSA
HHEECHHHHCCCHHHEEECEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296217