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The map label for this gene is asd [H]

Identifier: 55980514

GI number: 55980514

Start: 509255

End: 510250

Strand: Direct

Name: asd [H]

Synonym: TTHA0545

Alternate gene names: 55980514

Gene position: 509255-510250 (Clockwise)

Preceding gene: 55980513

Following gene: 55980516

Centisome position: 27.53

GC content: 68.57

Gene sequence:

>996_bases
ATGAGGGTAGCCGTGGTGGGGGCCACGGGGGCCGTGGGGCGGGAGATCCTCAAGGTCCTCGAGGCCCGAAACTTCCCCCT
TTCGGAGCTCAGGCTCTACGCCTCTCCCCGTTCCGCCGGGGTGCGCCTCGCGTTCAGGGGCGAGGAGATCCCCGTGGAGC
CCCTACCCGAGGGGCCTCTCCCTGTGGACCTCGTCCTGGCGAGCGCCGGGGGGGGCATCTCCAGGGCCAAGGCCTTGGTC
TGGGCGGAGGGCGGGGCCTTGGTGGTGGACAACTCCAGCGCCTGGCGCTACGAGCCCTGGGTGCCCCTGGTGGTGCCCGA
GGTGAACCGGGAGAAGATCTTCCAGCACCGGGGGATCATCGCTAACCCCAACTGCACCACGGCCATTTTGGCCATGGCCC
TTTGGCCCTTGCACCGGGCCTTCCAGGCCAAGCGGGTCATCGTGGCCACCTACCAGGCGGCTTCCGGGGCCGGGGCCAAG
GCCATGGAGGAGCTCCTTACCGAAACCCACCGCTTCCTCCACGGGGAGGCCCCCAAGGCCGAGGCCTTCGCCCACCCCCT
GCCCTTCAACGTCATCCCCCATATAGACGCCTTCCAGGAGAACGGCTACACCCGCGAGGAGATGAAGGTGGTCTGGGAGA
CCCACAAGATCTTCGGAGACGACACCATCCGGATCAGCGCCACGGCGGTGCGGGTGCCCACCTTAAGGGCCCACGCCGAG
GCGGTGAGCGTGGAGTTTGCCCGCCCCGTGACCCCGGAGGCGGCCCGGGAGGTCCTCAAGGAGGCCCCGGGGGTGGAGGT
GGTGGACGAGCCCGAGGCCAAGCGCTACCCCATGCCCCTCACCGCGAGCGGCAAGTGGGACGTGGAGGTGGGGAGGATCC
GGAAAAGCCTCGCCTTTGAAAACGGCCTGGACTTCTTCGTGGTGGGGGACCAGCTCTTGAAGGGGGCCGCCTTAAACGCC
GTGCAGATCGCCGAGGAGTGGCTTAAGGGCGCCTGA

Upstream 100 bases:

>100_bases
CTTCCCGCGAGCTGGAGCGGGAACTCTTTGGCGCCTTGACCCACCTGGTGGGCCACGTGAGCGCCATGTGGGAAGAGGCC
GAGTTTTTGGAGGAGGACGC

Downstream 100 bases:

>100_bases
GCCAAAGCCAGTACTCTAGGTTCCCCTCCTTTCCCGGGAGGGGGCTTTCCTTTTCCCCCAGGACCTGGAAGCCAAGCTCT
AGGGCCTTTTCCCGCACCCG

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MRVAVVGATGAVGREILKVLEARNFPLSELRLYASPRSAGVRLAFRGEEIPVEPLPEGPLPVDLVLASAGGGISRAKALV
WAEGGALVVDNSSAWRYEPWVPLVVPEVNREKIFQHRGIIANPNCTTAILAMALWPLHRAFQAKRVIVATYQAASGAGAK
AMEELLTETHRFLHGEAPKAEAFAHPLPFNVIPHIDAFQENGYTREEMKVVWETHKIFGDDTIRISATAVRVPTLRAHAE
AVSVEFARPVTPEAAREVLKEAPGVEVVDEPEAKRYPMPLTASGKWDVEVGRIRKSLAFENGLDFFVVGDQLLKGAALNA
VQIAEEWLKGA

Sequences:

>Translated_331_residues
MRVAVVGATGAVGREILKVLEARNFPLSELRLYASPRSAGVRLAFRGEEIPVEPLPEGPLPVDLVLASAGGGISRAKALV
WAEGGALVVDNSSAWRYEPWVPLVVPEVNREKIFQHRGIIANPNCTTAILAMALWPLHRAFQAKRVIVATYQAASGAGAK
AMEELLTETHRFLHGEAPKAEAFAHPLPFNVIPHIDAFQENGYTREEMKVVWETHKIFGDDTIRISATAVRVPTLRAHAE
AVSVEFARPVTPEAAREVLKEAPGVEVVDEPEAKRYPMPLTASGKWDVEVGRIRKSLAFENGLDFFVVGDQLLKGAALNA
VQIAEEWLKGA
>Mature_331_residues
MRVAVVGATGAVGREILKVLEARNFPLSELRLYASPRSAGVRLAFRGEEIPVEPLPEGPLPVDLVLASAGGGISRAKALV
WAEGGALVVDNSSAWRYEPWVPLVVPEVNREKIFQHRGIIANPNCTTAILAMALWPLHRAFQAKRVIVATYQAASGAGAK
AMEELLTETHRFLHGEAPKAEAFAHPLPFNVIPHIDAFQENGYTREEMKVVWETHKIFGDDTIRISATAVRVPTLRAHAE
AVSVEFARPVTPEAAREVLKEAPGVEVVDEPEAKRYPMPLTASGKWDVEVGRIRKSLAFENGLDFFVVGDQLLKGAALNA
VQIAEEWLKGA

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=333, Percent_Identity=33.9339339339339, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789841, Length=355, Percent_Identity=29.0140845070423, Blast_Score=105, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36080; Mature: 36080

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAVVGATGAVGREILKVLEARNFPLSELRLYASPRSAGVRLAFRGEEIPVEPLPEGPL
CEEEEEECCCHHHHHHHHHHHHCCCCHHHHEEEECCCCCCEEEEEECCCCCCCCCCCCCC
PVDLVLASAGGGISRAKALVWAEGGALVVDNSSAWRYEPWVPLVVPEVNREKIFQHRGII
CCEEEEECCCCCHHHCEEEEEECCCEEEEECCCCEEECCCCEEEECCCCHHHHHHHCCEE
ANPNCTTAILAMALWPLHRAFQAKRVIVATYQAASGAGAKAMEELLTETHRFLHGEAPKA
ECCCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCH
EAFAHPLPFNVIPHIDAFQENGYTREEMKVVWETHKIFGDDTIRISATAVRVPTLRAHAE
HHHCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHH
AVSVEFARPVTPEAAREVLKEAPGVEVVDEPEAKRYPMPLTASGKWDVEVGRIRKSLAFE
HEEEEECCCCCHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
NGLDFFVVGDQLLKGAALNAVQIAEEWLKGA
CCCEEEEECHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRVAVVGATGAVGREILKVLEARNFPLSELRLYASPRSAGVRLAFRGEEIPVEPLPEGPL
CEEEEEECCCHHHHHHHHHHHHCCCCHHHHEEEECCCCCCEEEEEECCCCCCCCCCCCCC
PVDLVLASAGGGISRAKALVWAEGGALVVDNSSAWRYEPWVPLVVPEVNREKIFQHRGII
CCEEEEECCCCCHHHCEEEEEECCCEEEEECCCCEEECCCCEEEECCCCHHHHHHHCCEE
ANPNCTTAILAMALWPLHRAFQAKRVIVATYQAASGAGAKAMEELLTETHRFLHGEAPKA
ECCCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCH
EAFAHPLPFNVIPHIDAFQENGYTREEMKVVWETHKIFGDDTIRISATAVRVPTLRAHAE
HHHCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHH
AVSVEFARPVTPEAAREVLKEAPGVEVVDEPEAKRYPMPLTASGKWDVEVGRIRKSLAFE
HEEEEECCCCCHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
NGLDFFVVGDQLLKGAALNAVQIAEEWLKGA
CCCEEEEECHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]