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The map label for this gene is aroA [H]

Identifier: 55980426

GI number: 55980426

Start: 428440

End: 429723

Strand: Direct

Name: aroA [H]

Synonym: TTHA0457

Alternate gene names: 55980426

Gene position: 428440-429723 (Clockwise)

Preceding gene: 55980425

Following gene: 55980427

Centisome position: 23.16

GC content: 73.52

Gene sequence:

>1284_bases
ATGGACGCGTTCCGCCTCGCGCCTTGTGGTCCCTTGCGGGGGCGCCTCCGCGTCCCCGGGGACAAGTCCGTGACCCACCG
CGGCCTCATGCTCCTCGCCCTGGCCGAGGGGGAGGGAAGGCTCTTCTACCCCTTGAAGGCGGGGGACACCCTCTCCACGG
CCCGGGTCCTCCAGGCCCTCGGGGCCGAGGTCCGGGAGGAGGGGCCCCACTTCCTCGTGCGGGGAAGGGGCCTAAGGTTC
CAGGAGCCCGAGGACGTCCTGGACTGCGGCAACGCCGGAACCCTCATGCGCCTCCTCCTCGGCCTCCTCGCGGGCCAGGA
GGGGCTTTTCGCCGTCCTCACCGGGGACGCCTCCTTGAGGCGCCGCCCCATGGGCCGGGTGGTGGCCCCCTTGAGGGCCA
TGGGGGCGAGGGTGGACGGGCGGGAGGAGGGGGAGAGGGCGCCCCTCGCCGTCCGGGGGGCGCCCCTGAGGGGTTTGCGC
TACACCCTCCCCGTGCCCAGCGCCCAGGTGAAGAGCGCCCTCCTCCTCGCCGGCCTCTTCGCCGAGGGGGTGACGGAGGT
GGAGGAGCCCACGCCCACCCGGGACCACACGGAGAGGCTCTTCCGCCACTTCGGCCTGCCCTTGGAGGTGGAGGGAAGGA
AGGTGCGCACCTGGCGCACGGGGCCCTTTCCCGCCAAGGACCTCGTGGTGCCCGGGGACTTCTCCTCGGCCGCCTTCTTC
CTGGTGGCGGCCCTCGTCACCCCGGGCTCGGAGGTGGTGGTGGAGGGGGTGGGGCTGAACCCCACCCGCACCGGCCTCCT
CACCGTCCTCAAGGCCATGGGGGCGGACCTGGAGTGGCAGGTCCTCGAGGGCGAGGCGGGGGAGCCCGTGGGGTGGGTGC
GGGCCCGGCATAGCCTCCTGAAGGGCGTGGCCGTGGACCCCGGCCTCATCCCCCTCATGGTGGACGAGGTGCCGGTCCTG
GCGGCGGCCGCCGCCTGGGCGGAAGGGGAGACCTACATCCCGGGCCTCTCCGAGCTTCGGGTCAAGGAGTCCGACCGGGT
CCGGGCCATCGCCGAAAACCTCCGGGCCCTCGGGGTGGAGGTGGAGGAAGGCCCGGACTGGCTCCGCATCCGGGGCGGGG
GGGTGAGGCCGGGCCGGGTGCGGCCCTTCCACGACCACCGCATCGCCATGGCCTTCGCCGTGGCCGGGCTTCCCGTGGGG
GTGGAGGTGGAGGAGCCCCACTGGGCCGAGATCTCCTACCCGGGTTTCTTCCAGGACCTCCTCAGGCTATGCGCGGCATC
GTGA

Upstream 100 bases:

>100_bases
CCACCGAGGAGGAGGTGGACCGGGCGGTGGCGGTCTTCCGGGAGGCCGTGGCCCGGGCCCGGGCTTGACCGGGCCCGAGC
GGAACGGAAGACTAGGGGGG

Downstream 100 bases:

>100_bases
CCATAGACGGGCCTTCGGCCTCCGGCAAGAGCTCCGTGGCCAGGCGGGTGGCGGCGGCCTTGGGCGTGCCCTACCTCTCC
AGCGGCCTCCTCTACCGGGC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MDAFRLAPCGPLRGRLRVPGDKSVTHRGLMLLALAEGEGRLFYPLKAGDTLSTARVLQALGAEVREEGPHFLVRGRGLRF
QEPEDVLDCGNAGTLMRLLLGLLAGQEGLFAVLTGDASLRRRPMGRVVAPLRAMGARVDGREEGERAPLAVRGAPLRGLR
YTLPVPSAQVKSALLLAGLFAEGVTEVEEPTPTRDHTERLFRHFGLPLEVEGRKVRTWRTGPFPAKDLVVPGDFSSAAFF
LVAALVTPGSEVVVEGVGLNPTRTGLLTVLKAMGADLEWQVLEGEAGEPVGWVRARHSLLKGVAVDPGLIPLMVDEVPVL
AAAAAWAEGETYIPGLSELRVKESDRVRAIAENLRALGVEVEEGPDWLRIRGGGVRPGRVRPFHDHRIAMAFAVAGLPVG
VEVEEPHWAEISYPGFFQDLLRLCAAS

Sequences:

>Translated_427_residues
MDAFRLAPCGPLRGRLRVPGDKSVTHRGLMLLALAEGEGRLFYPLKAGDTLSTARVLQALGAEVREEGPHFLVRGRGLRF
QEPEDVLDCGNAGTLMRLLLGLLAGQEGLFAVLTGDASLRRRPMGRVVAPLRAMGARVDGREEGERAPLAVRGAPLRGLR
YTLPVPSAQVKSALLLAGLFAEGVTEVEEPTPTRDHTERLFRHFGLPLEVEGRKVRTWRTGPFPAKDLVVPGDFSSAAFF
LVAALVTPGSEVVVEGVGLNPTRTGLLTVLKAMGADLEWQVLEGEAGEPVGWVRARHSLLKGVAVDPGLIPLMVDEVPVL
AAAAAWAEGETYIPGLSELRVKESDRVRAIAENLRALGVEVEEGPDWLRIRGGGVRPGRVRPFHDHRIAMAFAVAGLPVG
VEVEEPHWAEISYPGFFQDLLRLCAAS
>Mature_427_residues
MDAFRLAPCGPLRGRLRVPGDKSVTHRGLMLLALAEGEGRLFYPLKAGDTLSTARVLQALGAEVREEGPHFLVRGRGLRF
QEPEDVLDCGNAGTLMRLLLGLLAGQEGLFAVLTGDASLRRRPMGRVVAPLRAMGARVDGREEGERAPLAVRGAPLRGLR
YTLPVPSAQVKSALLLAGLFAEGVTEVEEPTPTRDHTERLFRHFGLPLEVEGRKVRTWRTGPFPAKDLVVPGDFSSAAFF
LVAALVTPGSEVVVEGVGLNPTRTGLLTVLKAMGADLEWQVLEGEAGEPVGWVRARHSLLKGVAVDPGLIPLMVDEVPVL
AAAAAWAEGETYIPGLSELRVKESDRVRAIAENLRALGVEVEEGPDWLRIRGGGVRPGRVRPFHDHRIAMAFAVAGLPVG
VEVEEPHWAEISYPGFFQDLLRLCAAS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=443, Percent_Identity=30.9255079006772, Blast_Score=147, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6320332, Length=454, Percent_Identity=26.8722466960352, Blast_Score=108, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46029; Mature: 46029

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAFRLAPCGPLRGRLRVPGDKSVTHRGLMLLALAEGEGRLFYPLKAGDTLSTARVLQAL
CCCCCCCCCCCCCCCEECCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHHHHH
GAEVREEGPHFLVRGRGLRFQEPEDVLDCGNAGTLMRLLLGLLAGQEGLFAVLTGDASLR
HHHHHHCCCEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHH
RRPMGRVVAPLRAMGARVDGREEGERAPLAVRGAPLRGLRYTLPVPSAQVKSALLLAGLF
HCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCEEECCCCCHHHHHHHHHHHHH
AEGVTEVEEPTPTRDHTERLFRHFGLPLEVEGRKVRTWRTGPFPAKDLVVPGDFSSAAFF
HHHHHHHCCCCCCHHHHHHHHHHCCCCEEECCCEEEEEECCCCCCCCEEECCCCCHHHHH
LVAALVTPGSEVVVEGVGLNPTRTGLLTVLKAMGADLEWQVLEGEAGEPVGWVRARHSLL
HHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHH
KGVAVDPGLIPLMVDEVPVLAAAAAWAEGETYIPGLSELRVKESDRVRAIAENLRALGVE
HCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCHHHHEECCCHHHHHHHHHHHHHCCE
VEEGPDWLRIRGGGVRPGRVRPFHDHRIAMAFAVAGLPVGVEVEEPHWAEISYPGFFQDL
EECCCCEEEEECCCCCCCCCCCCCCCHHEEHHHHHCCCCCEEECCCCCEEECCCHHHHHH
LRLCAAS
HHHHCCC
>Mature Secondary Structure
MDAFRLAPCGPLRGRLRVPGDKSVTHRGLMLLALAEGEGRLFYPLKAGDTLSTARVLQAL
CCCCCCCCCCCCCCCEECCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHHHHH
GAEVREEGPHFLVRGRGLRFQEPEDVLDCGNAGTLMRLLLGLLAGQEGLFAVLTGDASLR
HHHHHHCCCEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHH
RRPMGRVVAPLRAMGARVDGREEGERAPLAVRGAPLRGLRYTLPVPSAQVKSALLLAGLF
HCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCEEECCCCCHHHHHHHHHHHHH
AEGVTEVEEPTPTRDHTERLFRHFGLPLEVEGRKVRTWRTGPFPAKDLVVPGDFSSAAFF
HHHHHHHCCCCCCHHHHHHHHHHCCCCEEECCCEEEEEECCCCCCCCEEECCCCCHHHHH
LVAALVTPGSEVVVEGVGLNPTRTGLLTVLKAMGADLEWQVLEGEAGEPVGWVRARHSLL
HHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHH
KGVAVDPGLIPLMVDEVPVLAAAAAWAEGETYIPGLSELRVKESDRVRAIAENLRALGVE
HCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCHHHHEECCCHHHHHHHHHHHHHCCE
VEEGPDWLRIRGGGVRPGRVRPFHDHRIAMAFAVAGLPVGVEVEEPHWAEISYPGFFQDL
EECCCCEEEEECCCCCCCCCCCCCCCHHEEHHHHHCCCCCEEECCCCCEEECCCHHHHHH
LRLCAAS
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA