Definition Thermus thermophilus HB8 chromosome, complete genome.
Accession NC_006461
Length 1,849,742

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The map label for this gene is mntB [H]

Identifier: 55980422

GI number: 55980422

Start: 425254

End: 425994

Strand: Direct

Name: mntB [H]

Synonym: TTHA0453

Alternate gene names: 55980422

Gene position: 425254-425994 (Clockwise)

Preceding gene: 55980421

Following gene: 55980423

Centisome position: 22.99

GC content: 71.52

Gene sequence:

>741_bases
ATGTGGGCGGTGGAGACCCAGGGGCTTGCGGTGCGCTTCGGGCAGTACCAGGCCTTGGAGGACGTCTCCTTGAGGGTGCC
CGAGGGCAGCTTCGTGGCCGTGGTGGGCCCCAACGGGGCAGGGAAGAGCACCCTTCTCAAGGCCCTTTTGGGCCTCGTGC
CCTTCCGGGGGGAGGTGCGGATCTTCGGCCGCCCCTTGGGCCAGGCCGATCCCTTCTGGTTCGGCTACGTGCCCCAGATC
AAGACCTTTGACCGCACCTTCCCCGCCCTGGCCTTGGAGCTCGTGGTCTCGGGGCTCCGCCGCGCCTGGCCCTTTCGCGT
GGGGGAGGAGGAGCGCAGGCGGGCCCTCGAGGCCTTGGGGCGGGTGGGGGCGTTGGAGCTCGCCCACCGCCCCTTGGGGC
GGCTTTCCGGGGGGCAGTTGCAGCGGGTCTACCTGGCCCGGGCCCTGGTGCGCAGGCCCCGCCTCCTCCTTTTGGACGAG
CCCGCCACCGGGGTGGACCGGCTGGGGGAGGTGGACCTCTACCGGCACCTGGAGGCCTACCAGGAGGAGACGGGGGCCAC
GATCCTCATGATCACCCACGACTGGGAGGCGGCCCACCACGCCAGCCACGTCCTGGTGCTGAACCGCCGCGTGATCGGCT
TCGGCCCGCCGGAGCGGGCCCTCTCCGAGGAGTGCCTCCGCCAGGCCTTCGGCCATTTGGGGCACGAGCACGCCCTTTTC
CTGGGAGGCGGCCGTGCTTGA

Upstream 100 bases:

>100_bases
CAAGGCCTACAAGCGGCGCAAGCGCTTCATGTGAGCCCAAAAGGCCCCTGCGCAAGCGGGGGCCTGGCGGCGCAAATGAA
AATGCGCTATCGTTATTGGT

Downstream 100 bases:

>100_bases
GGCCTTGGGCTACCCCTTCTTCCAGAGGGCCCTCCTCGCCGGCCTCTTGGTGAGCCTGCTTGGAGGGGCGCTTTCCGCCT
TCGTGGTGCAGAGAAGGCTT

Product: Mn2+/Zn2+ ABC transporter ATP-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MWAVETQGLAVRFGQYQALEDVSLRVPEGSFVAVVGPNGAGKSTLLKALLGLVPFRGEVRIFGRPLGQADPFWFGYVPQI
KTFDRTFPALALELVVSGLRRAWPFRVGEEERRRALEALGRVGALELAHRPLGRLSGGQLQRVYLARALVRRPRLLLLDE
PATGVDRLGEVDLYRHLEAYQEETGATILMITHDWEAAHHASHVLVLNRRVIGFGPPERALSEECLRQAFGHLGHEHALF
LGGGRA

Sequences:

>Translated_246_residues
MWAVETQGLAVRFGQYQALEDVSLRVPEGSFVAVVGPNGAGKSTLLKALLGLVPFRGEVRIFGRPLGQADPFWFGYVPQI
KTFDRTFPALALELVVSGLRRAWPFRVGEEERRRALEALGRVGALELAHRPLGRLSGGQLQRVYLARALVRRPRLLLLDE
PATGVDRLGEVDLYRHLEAYQEETGATILMITHDWEAAHHASHVLVLNRRVIGFGPPERALSEECLRQAFGHLGHEHALF
LGGGRA
>Mature_246_residues
MWAVETQGLAVRFGQYQALEDVSLRVPEGSFVAVVGPNGAGKSTLLKALLGLVPFRGEVRIFGRPLGQADPFWFGYVPQI
KTFDRTFPALALELVVSGLRRAWPFRVGEEERRRALEALGRVGALELAHRPLGRLSGGQLQRVYLARALVRRPRLLLLDE
PATGVDRLGEVDLYRHLEAYQEETGATILMITHDWEAAHHASHVLVLNRRVIGFGPPERALSEECLRQAFGHLGHEHALF
LGGGRA

Specific function: This protein is probably a component of a manganese permease, a binding protein-dependent, ATP-driven transport system. Probably responsible for energy coupling to the transport system [H]

COG id: COG1121

COG function: function code P; ABC-type Mn/Zn transport systems, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI171184400, Length=218, Percent_Identity=32.1100917431193, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI9955966, Length=214, Percent_Identity=29.4392523364486, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI45243524, Length=214, Percent_Identity=29.4392523364486, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI9955968, Length=214, Percent_Identity=29.4392523364486, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI31657092, Length=196, Percent_Identity=31.1224489795918, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI27436953, Length=193, Percent_Identity=30.5699481865285, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI148612853, Length=169, Percent_Identity=38.4615384615385, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI156105685, Length=200, Percent_Identity=29.5, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI255708477, Length=219, Percent_Identity=29.6803652968037, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI27881501, Length=214, Percent_Identity=28.0373831775701, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI30795238, Length=214, Percent_Identity=28.0373831775701, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI148612844, Length=219, Percent_Identity=29.6803652968037, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI11967969, Length=161, Percent_Identity=33.5403726708075, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI153792144, Length=160, Percent_Identity=32.5, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI27477115, Length=212, Percent_Identity=31.6037735849057, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI46592898, Length=159, Percent_Identity=34.5911949685535, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI46592915, Length=159, Percent_Identity=34.5911949685535, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI46592964, Length=159, Percent_Identity=34.5911949685535, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI46592971, Length=159, Percent_Identity=34.5911949685535, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI46592956, Length=159, Percent_Identity=34.5911949685535, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI46592978, Length=159, Percent_Identity=34.5911949685535, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI6005701, Length=207, Percent_Identity=31.4009661835749, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1788165, Length=217, Percent_Identity=40.5529953917051, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI87081791, Length=235, Percent_Identity=33.1914893617021, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786803, Length=230, Percent_Identity=30.4347826086957, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1790739, Length=239, Percent_Identity=32.2175732217573, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787712, Length=220, Percent_Identity=31.8181818181818, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI87081709, Length=224, Percent_Identity=32.5892857142857, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1790544, Length=214, Percent_Identity=32.2429906542056, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788761, Length=214, Percent_Identity=36.4485981308411, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87081834, Length=206, Percent_Identity=36.8932038834951, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787029, Length=241, Percent_Identity=31.9502074688797, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786345, Length=227, Percent_Identity=33.920704845815, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1786563, Length=206, Percent_Identity=33.9805825242718, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787370, Length=226, Percent_Identity=33.1858407079646, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789032, Length=223, Percent_Identity=31.390134529148, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787164, Length=206, Percent_Identity=35.9223300970874, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87081782, Length=252, Percent_Identity=30.1587301587302, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787500, Length=201, Percent_Identity=32.8358208955224, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI48994943, Length=240, Percent_Identity=29.5833333333333, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790467, Length=248, Percent_Identity=30.6451612903226, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789873, Length=193, Percent_Identity=34.7150259067358, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789891, Length=192, Percent_Identity=38.0208333333333, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI87082267, Length=202, Percent_Identity=31.1881188118812, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789593, Length=243, Percent_Identity=28.3950617283951, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786398, Length=222, Percent_Identity=31.0810810810811, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789864, Length=235, Percent_Identity=29.7872340425532, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786698, Length=206, Percent_Identity=28.1553398058252, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1788506, Length=215, Percent_Identity=27.4418604651163, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787089, Length=222, Percent_Identity=31.5315315315315, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786975, Length=198, Percent_Identity=30.3030303030303, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786703, Length=217, Percent_Identity=34.5622119815668, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1786319, Length=208, Percent_Identity=33.6538461538462, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1786654, Length=203, Percent_Identity=33.4975369458128, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788225, Length=221, Percent_Identity=33.4841628959276, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1786872, Length=219, Percent_Identity=31.0502283105023, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789672, Length=197, Percent_Identity=27.9187817258883, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1787041, Length=217, Percent_Identity=29.0322580645161, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787105, Length=216, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI48995001, Length=218, Percent_Identity=28.8990825688073, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789991, Length=230, Percent_Identity=26.0869565217391, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI87082064, Length=179, Percent_Identity=34.6368715083799, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788644, Length=234, Percent_Identity=31.6239316239316, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787112, Length=207, Percent_Identity=31.8840579710145, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788002, Length=227, Percent_Identity=29.9559471365639, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787772, Length=179, Percent_Identity=30.1675977653631, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788897, Length=189, Percent_Identity=29.6296296296296, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789751, Length=213, Percent_Identity=29.5774647887324, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=202, Percent_Identity=29.7029702970297, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115534520, Length=219, Percent_Identity=27.3972602739726, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71992290, Length=218, Percent_Identity=33.0275229357798, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17569145, Length=222, Percent_Identity=30.6306306306306, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17510237, Length=191, Percent_Identity=26.1780104712042, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115533592, Length=218, Percent_Identity=27.9816513761468, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565938, Length=199, Percent_Identity=28.643216080402, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533608, Length=190, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=224, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI212646699, Length=205, Percent_Identity=27.3170731707317, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71983523, Length=210, Percent_Identity=27.6190476190476, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=210, Percent_Identity=27.6190476190476, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71983510, Length=210, Percent_Identity=27.6190476190476, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538654, Length=187, Percent_Identity=28.3422459893048, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=230, Percent_Identity=30, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=179, Percent_Identity=35.7541899441341, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323217, Length=215, Percent_Identity=29.3023255813954, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24650855, Length=198, Percent_Identity=31.8181818181818, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24650853, Length=198, Percent_Identity=31.8181818181818, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641565, Length=226, Percent_Identity=30.0884955752212, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281362751, Length=198, Percent_Identity=31.8181818181818, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28574259, Length=256, Percent_Identity=29.6875, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24666092, Length=195, Percent_Identity=29.2307692307692, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28574744, Length=195, Percent_Identity=31.7948717948718, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920532, Length=144, Percent_Identity=31.9444444444444, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24580930, Length=144, Percent_Identity=31.9444444444444, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17647959, Length=214, Percent_Identity=32.2429906542056, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI85725262, Length=180, Percent_Identity=32.2222222222222, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI85726357, Length=208, Percent_Identity=27.8846153846154, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI45552805, Length=165, Percent_Identity=30.3030303030303, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17647219, Length=165, Percent_Identity=30.3030303030303, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27277; Mature: 27277

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MWAVETQGLAVRFGQYQALEDVSLRVPEGSFVAVVGPNGAGKSTLLKALLGLVPFRGEVR
CCCCCCCCEEEECCCHHHHCCCEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEE
IFGRPLGQADPFWFGYVPQIKTFDRTFPALALELVVSGLRRAWPFRVGEEERRRALEALG
EEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
RVGALELAHRPLGRLSGGQLQRVYLARALVRRPRLLLLDEPATGVDRLGEVDLYRHLEAY
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHCHHHHHHHHHHH
QEETGATILMITHDWEAAHHASHVLVLNRRVIGFGPPERALSEECLRQAFGHLGHEHALF
HHHCCCEEEEEECCCCHHHHCCEEEEEECEEEECCCCHHHHHHHHHHHHHHHCCCCCEEE
LGGGRA
ECCCCC
>Mature Secondary Structure
MWAVETQGLAVRFGQYQALEDVSLRVPEGSFVAVVGPNGAGKSTLLKALLGLVPFRGEVR
CCCCCCCCEEEECCCHHHHCCCEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEE
IFGRPLGQADPFWFGYVPQIKTFDRTFPALALELVVSGLRRAWPFRVGEEERRRALEALG
EEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
RVGALELAHRPLGRLSGGQLQRVYLARALVRRPRLLLLDEPATGVDRLGEVDLYRHLEAY
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHCHHHHHHHHHHH
QEETGATILMITHDWEAAHHASHVLVLNRRVIGFGPPERALSEECLRQAFGHLGHEHALF
HHHCCCEEEEEECCCCHHHHCCEEEEEECEEEECCCCHHHHHHHHHHHHHHHCCCCCEEE
LGGGRA
ECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]