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The map label for this gene is livK [C]

Identifier: 55980420

GI number: 55980420

Start: 423086

End: 424309

Strand: Direct

Name: livK [C]

Synonym: TTHA0451

Alternate gene names: 55980420

Gene position: 423086-424309 (Clockwise)

Preceding gene: 55980419

Following gene: 55980421

Centisome position: 22.87

GC content: 66.09

Gene sequence:

>1224_bases
ATGGGGTTGGCGAAGGGAGGGAAGCGTATGCGAAGGACACTGGCAGGCATCGCGGCGGTCTTGGGGTTGGCTTTAGGCCA
GCAGCAGGTGACCCTCTTCTGGTCGGGGGCCATCACCGGGCCCACCTCGGACGCGGGGGCCCCTTACGGGGCGGCGGTGG
AGGACTACTGCAAGTGGGCCAACGAGCGGAAGCTCGTGCCCGGGGTGGTCTTCAACTGTGTGGTGCGGGACGACCAGTAC
AACAACGCCAACACCCAGCGCTTCTTTGAGGAGGCGGTGGACCGCTTCAAGATCCCCGTCTTCCTCTCCTACGCCACGGG
GGCGAACCTCCAGCTCAAGCCCCTGATCCAGGAGCTCAGGATCCCCACCATCCCCGCCTCCATGCACATTGAGCTCATTG
ACCCGCCCAACAACGATTACATCTTCCTCCCCACCACCAGCTACTCCGAGCAGGTGGTGGCCCTTCTGGAGTACATCGCC
CGCGAGAAGAAGGGGGCCAAGGTGGCCCTGGTGGTCCACCCCTCCCCCTTCGGCCGGGCTCCGGTGGAGGACGCGAGGAA
GGCGGCCCGGGAGCTCGGGCTTCAGATCGTGGACGTCCAGGAGGTGGGAAGCGGCAACCTGGACAACACCGCCCTCCTCA
AGCGCTTTGAGCAGGCCGGGGTGGAGTACGTGGTCCACCAGAACGTGGCGGGCCCCGTGGCCAACATCCTCAAGGACGCC
AAGCGCCTGGGCCTGAAGATGCGCCACCTGGGGGCCCACTACACGGGGGGGCCGGACCTCATCGCCTTGGCCGGGGACGC
GGCGGAGGGCTTCCTCTGGGCCACGAGCTTCTACATGGCCCACGAGGACACCCCGGGGATCCGGCTGCAGAAGGAGATCG
GGCGGAAGTACGGCCGTCCCGAAAACTTCATTGAGAGCGTGAACTACACGAACGGGATGCTCGTCGCGTCCATCGCCGTG
GAGGCCATCCGCAGGGCCCAGGAGCGGTTCAAGCGGATCACCAACGAGACCGTCTACCAGGCCATCGTCGGCATGAACGG
GCCCAACGCCTTCAAGCCGGGCTTCGCCGTCTCCACCAAGCAGGGCGTGGAGATTGACTTCACCAAGAGCGAGCACACGG
GGGCGGAAGGCCTCCGGATCCTCGAGGCCAAGGGAGGGCGCTTCGTCCCCGTCACGGAGCCCTTCACCTCGGCCCTCTTC
CGCAAGGTGCACTACGGCAAGTAG

Upstream 100 bases:

>100_bases
CCTCTTCCTGGTGTTTGAGCCCAGGGGGCTTTACAACTGGTGGCGCGTGATGCGAAGCTACTTCCGCACCTGGCCCTTTA
GGTACTAGGCAACCCCCCTC

Downstream 100 bases:

>100_bases
ACCCCGGGAGCCCGGGGTGCCCCGGGCCCCTTTCCCACAAGGCCATGGACGCTTTGAACCCGATCCGTCCCGAGGACCTC
GGCCCCATCCTCCTCCTCGT

Product: branched chain amino acid ABC transporter amino acid-binding protein

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: None

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MGLAKGGKRMRRTLAGIAAVLGLALGQQQVTLFWSGAITGPTSDAGAPYGAAVEDYCKWANERKLVPGVVFNCVVRDDQY
NNANTQRFFEEAVDRFKIPVFLSYATGANLQLKPLIQELRIPTIPASMHIELIDPPNNDYIFLPTTSYSEQVVALLEYIA
REKKGAKVALVVHPSPFGRAPVEDARKAARELGLQIVDVQEVGSGNLDNTALLKRFEQAGVEYVVHQNVAGPVANILKDA
KRLGLKMRHLGAHYTGGPDLIALAGDAAEGFLWATSFYMAHEDTPGIRLQKEIGRKYGRPENFIESVNYTNGMLVASIAV
EAIRRAQERFKRITNETVYQAIVGMNGPNAFKPGFAVSTKQGVEIDFTKSEHTGAEGLRILEAKGGRFVPVTEPFTSALF
RKVHYGK

Sequences:

>Translated_407_residues
MGLAKGGKRMRRTLAGIAAVLGLALGQQQVTLFWSGAITGPTSDAGAPYGAAVEDYCKWANERKLVPGVVFNCVVRDDQY
NNANTQRFFEEAVDRFKIPVFLSYATGANLQLKPLIQELRIPTIPASMHIELIDPPNNDYIFLPTTSYSEQVVALLEYIA
REKKGAKVALVVHPSPFGRAPVEDARKAARELGLQIVDVQEVGSGNLDNTALLKRFEQAGVEYVVHQNVAGPVANILKDA
KRLGLKMRHLGAHYTGGPDLIALAGDAAEGFLWATSFYMAHEDTPGIRLQKEIGRKYGRPENFIESVNYTNGMLVASIAV
EAIRRAQERFKRITNETVYQAIVGMNGPNAFKPGFAVSTKQGVEIDFTKSEHTGAEGLRILEAKGGRFVPVTEPFTSALF
RKVHYGK
>Mature_406_residues
GLAKGGKRMRRTLAGIAAVLGLALGQQQVTLFWSGAITGPTSDAGAPYGAAVEDYCKWANERKLVPGVVFNCVVRDDQYN
NANTQRFFEEAVDRFKIPVFLSYATGANLQLKPLIQELRIPTIPASMHIELIDPPNNDYIFLPTTSYSEQVVALLEYIAR
EKKGAKVALVVHPSPFGRAPVEDARKAARELGLQIVDVQEVGSGNLDNTALLKRFEQAGVEYVVHQNVAGPVANILKDAK
RLGLKMRHLGAHYTGGPDLIALAGDAAEGFLWATSFYMAHEDTPGIRLQKEIGRKYGRPENFIESVNYTNGMLVASIAVE
AIRRAQERFKRITNETVYQAIVGMNGPNAFKPGFAVSTKQGVEIDFTKSEHTGAEGLRILEAKGGRFVPVTEPFTSALFR
KVHYGK

Specific function: This Protein Is A Component Of The Leucine-Specific Transport System, Which Is One Of The Two Periplasmic Binding Protein-Dependent Transport Systems Of The High-Affinity Transport Of The Branched-Chain Amino Acids In E.Coli. [C]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 44576; Mature: 44444

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLAKGGKRMRRTLAGIAAVLGLALGQQQVTLFWSGAITGPTSDAGAPYGAAVEDYCKWA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECEECCCCCCCCCCCCCHHHHHHHHC
NERKLVPGVVFNCVVRDDQYNNANTQRFFEEAVDRFKIPVFLSYATGANLQLKPLIQELR
CCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCC
IPTIPASMHIELIDPPNNDYIFLPTTSYSEQVVALLEYIAREKKGAKVALVVHPSPFGRA
CCCCCCCEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
PVEDARKAARELGLQIVDVQEVGSGNLDNTALLKRFEQAGVEYVVHQNVAGPVANILKDA
CHHHHHHHHHHHCCEEEEHHHCCCCCCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHH
KRLGLKMRHLGAHYTGGPDLIALAGDAAEGFLWATSFYMAHEDTPGIRLQKEIGRKYGRP
HHHCCHHHHCCCCCCCCCCEEEEECCCCCCEEEEEEEEEEECCCCCCEEHHHHHHHCCCC
ENFIESVNYTNGMLVASIAVEAIRRAQERFKRITNETVYQAIVGMNGPNAFKPGFAVSTK
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCC
QGVEIDFTKSEHTGAEGLRILEAKGGRFVPVTEPFTSALFRKVHYGK
CCCEEEEECCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
GLAKGGKRMRRTLAGIAAVLGLALGQQQVTLFWSGAITGPTSDAGAPYGAAVEDYCKWA
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECEECCCCCCCCCCCCCHHHHHHHHC
NERKLVPGVVFNCVVRDDQYNNANTQRFFEEAVDRFKIPVFLSYATGANLQLKPLIQELR
CCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCC
IPTIPASMHIELIDPPNNDYIFLPTTSYSEQVVALLEYIAREKKGAKVALVVHPSPFGRA
CCCCCCCEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
PVEDARKAARELGLQIVDVQEVGSGNLDNTALLKRFEQAGVEYVVHQNVAGPVANILKDA
CHHHHHHHHHHHCCEEEEHHHCCCCCCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHH
KRLGLKMRHLGAHYTGGPDLIALAGDAAEGFLWATSFYMAHEDTPGIRLQKEIGRKYGRP
HHHCCHHHHCCCCCCCCCCEEEEECCCCCCEEEEEEEEEEECCCCCCEEHHHHHHHCCCC
ENFIESVNYTNGMLVASIAVEAIRRAQERFKRITNETVYQAIVGMNGPNAFKPGFAVSTK
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCC
QGVEIDFTKSEHTGAEGLRILEAKGGRFVPVTEPFTSALFRKVHYGK
CCCEEEEECCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA