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The map label for this gene is tagA [H]

Identifier: 55980391

GI number: 55980391

Start: 399987

End: 400691

Strand: Reverse

Name: tagA [H]

Synonym: TTHA0422

Alternate gene names: 55980391

Gene position: 400691-399987 (Counterclockwise)

Preceding gene: 55980392

Following gene: 55980390

Centisome position: 21.66

GC content: 70.07

Gene sequence:

>705_bases
ATGGAAAGGCTGACCCTCCTCGGCCTCCCCCTAGACCCCGTGGACATGGAGGAGGCCCTCAAGCGCATCGGGGGCTTCCT
CCAAGAGGAAAGGACCCACCAGGTGGTGACCCTGAACCCCGAGATCGCCGTAAGGGCCCAGGAGGACGAGGCCCTGAGGC
GGGCCGTCCTCGAGGCCGAGCTCGTCACCCCGGACGGGGTGGGGATCCTCTGGGCGGTGCGGCGCCTCCACGGCCTTTCC
CTCAAGGAACGGGTCACGGGGATTGACCTCACCCTCGCCCTCCTCCGCCGGTTTCCGGGGGTCCGGGTCTACCTCCTCGG
GGGGAAGCCGGGGGTGGCCGAGGGAGCCGCCCGGGAGGTGGAGCGCCTGGGGGGCGTGGTGGTGGGCCTCCACCACGGCT
ACTTCCAGGAGGAGGCCCCGGTGGTGGCGGCCATCCAAAAGGCCGCCCCCGACCTCCTCCTGGTGGGCATGGGGGAAAGG
CAGGAAGCCTTCATCCACCGCCACAAGCCCCACCTCGAGGCCCGGGTGGCCATAGGGGTGGGGGGCACCCTGGACGTCCT
TGCGGGAGAGGCCAGGCGCCCCCCCCTTTGGGCCCAGAGGCTCGGCCTGGAGTGGCTTTTAAGGGTGGGGCTAGACCCAA
AGCGCTGGCGGAGGGCCCCCAGGCTTTTCCGCTTCGCTTACCTCGTCCTCAAGGAGAAGCGCTAA

Upstream 100 bases:

>100_bases
TCGGGGTGGACCCCGTGGTGCCCAAGCTCGCCGAGGTCCGCTTCTTTCCCAAGGAGGCCCACGGGCTTAGCCGGGACCGG
TACGCCCAAAGGTTCATCCC

Downstream 100 bases:

>100_bases
AGTAGACCCATGCGGCGCTTCCTCGCAGGCCTTTGGCTTCTCGGCCTCGCCCTCGGCCAGGGCCTCGTCCTTCCCTTTGA
GGGGCCCAAAGGGTACGGCC

Product: UDP-N-acetyl-D-mannosaminuronic acid transferase

Products: NA

Alternate protein names: Major teichoic acid biosynthesis protein A; N-acetylglucosaminyldiphospho-undecaprenol N-acetyl-beta-D-mannosaminyltransferase; UDP-N-acetylmannosamine transferase [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MERLTLLGLPLDPVDMEEALKRIGGFLQEERTHQVVTLNPEIAVRAQEDEALRRAVLEAELVTPDGVGILWAVRRLHGLS
LKERVTGIDLTLALLRRFPGVRVYLLGGKPGVAEGAAREVERLGGVVVGLHHGYFQEEAPVVAAIQKAAPDLLLVGMGER
QEAFIHRHKPHLEARVAIGVGGTLDVLAGEARRPPLWAQRLGLEWLLRVGLDPKRWRRAPRLFRFAYLVLKEKR

Sequences:

>Translated_234_residues
MERLTLLGLPLDPVDMEEALKRIGGFLQEERTHQVVTLNPEIAVRAQEDEALRRAVLEAELVTPDGVGILWAVRRLHGLS
LKERVTGIDLTLALLRRFPGVRVYLLGGKPGVAEGAAREVERLGGVVVGLHHGYFQEEAPVVAAIQKAAPDLLLVGMGER
QEAFIHRHKPHLEARVAIGVGGTLDVLAGEARRPPLWAQRLGLEWLLRVGLDPKRWRRAPRLFRFAYLVLKEKR
>Mature_234_residues
MERLTLLGLPLDPVDMEEALKRIGGFLQEERTHQVVTLNPEIAVRAQEDEALRRAVLEAELVTPDGVGILWAVRRLHGLS
LKERVTGIDLTLALLRRFPGVRVYLLGGKPGVAEGAAREVERLGGVVVGLHHGYFQEEAPVVAAIQKAAPDLLLVGMGER
QEAFIHRHKPHLEARVAIGVGGTLDVLAGEARRPPLWAQRLGLEWLLRVGLDPKRWRRAPRLFRFAYLVLKEKR

Specific function: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, a key lipid intermediate in the de novo synthesis of teichoic acid (Potential) [H]

COG id: COG1922

COG function: function code M; Teichoic acid biosynthesis proteins

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 26 family [H]

Homologues:

Organism=Escherichia coli, GI2367289, Length=208, Percent_Identity=31.7307692307692, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004629 [H]

Pfam domain/function: PF03808 Glyco_tran_WecB [H]

EC number: =2.4.1.187 [H]

Molecular weight: Translated: 26108; Mature: 26108

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERLTLLGLPLDPVDMEEALKRIGGFLQEERTHQVVTLNPEIAVRAQEDEALRRAVLEAE
CCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEEECHHHHHHHHHHHHH
LVTPDGVGILWAVRRLHGLSLKERVTGIDLTLALLRRFPGVRVYLLGGKPGVAEGAAREV
CCCCCCCHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
ERLGGVVVGLHHGYFQEEAPVVAAIQKAAPDLLLVGMGERQEAFIHRHKPHLEARVAIGV
HHHCCEEEEECCCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEEEEEC
GGTLDVLAGEARRPPLWAQRLGLEWLLRVGLDPKRWRRAPRLFRFAYLVLKEKR
CCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MERLTLLGLPLDPVDMEEALKRIGGFLQEERTHQVVTLNPEIAVRAQEDEALRRAVLEAE
CCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEEECHHHHHHHHHHHHH
LVTPDGVGILWAVRRLHGLSLKERVTGIDLTLALLRRFPGVRVYLLGGKPGVAEGAAREV
CCCCCCCHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
ERLGGVVVGLHHGYFQEEAPVVAAIQKAAPDLLLVGMGERQEAFIHRHKPHLEARVAIGV
HHHCCEEEEECCCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEEEEEC
GGTLDVLAGEARRPPLWAQRLGLEWLLRVGLDPKRWRRAPRLFRFAYLVLKEKR
CCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906926; 9384377; 11882717 [H]