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The map label for this gene is prsA [H]

Identifier: 55980321

GI number: 55980321

Start: 331985

End: 333811

Strand: Direct

Name: prsA [H]

Synonym: TTHA0352

Alternate gene names: 55980321

Gene position: 331985-333811 (Clockwise)

Preceding gene: 55980317

Following gene: 55980322

Centisome position: 17.95

GC content: 67.49

Gene sequence:

>1827_bases
GTGTTCGGTCTCAGCAAACGCGCCATCACCATCCTCTTCGGCCTTCTGGCCCTGGCCTTCGCCCTGGGGGCCATCCTCCT
CTTCACCCCCCAGGCGGCGCAGCAGACCCGGGGCAAGCCGGTCCTTTGGGTGAACGGCAAGGCCCTCTACGAGCTGGACC
TCCTCCGGCTCCAAGGAAACGACCCCCTCTACGCCGCAAGCCCCGAGGGCCTGCTCAAGACCTTGGTGGACACCTACTTC
CTGGAGCAGGTCATCCTCACCGAGGCCCTGAAGCAGGACGCCGCCCGGGTGCGGGTCTCCAGCGCCGAGGTGCGCCAGGA
GGTGAACCGCATCCGGGAGCAGTTCGGCCTAAAGGACAAGGCGGCCTACGAGCAGTTCCTCAACCAGGTGGGTTACACGG
ACGCCCAGCTTAGGGCCGAGGTCAAGACCCAGCTCCAGATCCAGAAGCGTCTGGAGCAGATCCGCTCGGGCGCTAAGCCC
ACCGAGGAGGAGGTGCGGTTCTACTACGAGGTCTTCAAGGAGAACTACAGGACCGAGCCCCGGGTGAAGGCCCGCCAGAT
CGTGGTGGACGACAAGGCCCTCGCCGAGGAGCTCGCCGCCAAGGCCAAGGCCGGGGAGGACTTCGCCGCCCTGGCCCGCC
AGCACTCCAAGGTGGGGGCGGAGCAGGGGGGCGCTTTGGGGGCGGGCCCCGGGGAGGCGGAGCCCAAGCCCGTGACCCAG
GTGGTCTTCCCCACGGAGGTGGGGGAAGCGGTCTTCGCCCTGAAGGGGCCGGGCGTGGTGGGGCCCATCGCCGCAGGAGG
CCGGTACTACATCGTGAAGGTGGAGGAATACCTCCCCTCTACCCTCCCCGCCTTTGAGGAGGTCAAGGACCGGGTGGCCC
AGGACGCAGAGAGGGCCAAGGGGAACGGCGTCCTCGAGGCCTACCTGGAAGAGCTCCGCAAGAAGGCCCAGGTCCGCTTC
GCCGAGGACAACCCCTACGCCTACCAGAACCCGCCCGTGGCCAAGGTCAACGAGAAGGAGATCCTCCTCAGCGAGGTGCT
CCAGCCCGTCTTCTCCAACCAGCAGACGGTGGCCCTGGTCCAGCAGGGCCTGGGGGAGCTCGCCGTCCAGTTCTTCCTTC
CCCAGACCCTGGAGAACCTCATTGACCGGGAGCTCCTGGTGGAGGCGGCCCGAAAAAGCGGCAAGCCCTTCATCGGCTCC
AAGGCGGAGATCGCCGAGGCCTACCTCCGCTACGAGACCCGGGACGTGACGGCGAGCGAGGAGGAGGCCCGGGCCTTCTA
CAGCGAGAACCCCGCCCTCTTCACCGTGCCCGCGAGCGCCAAGGTGATCGGGGTGAACTTCAAGGAGGAAGCCCAGGCCA
AGGCCTTCCGGGCCGCGGCCCTTAGGGGCGGGGACCTCGAGGCCCTGGCCAAGGCCCAAGAAGGCACGGTCACCGACTAC
GGCACCGTGAACCCCAACCAGCTCCCCGCCGTCCTGGACCGCCTGGTCTTCAAGATCACCGAGACCTTCCCCCAAGGCCC
CTTGGGGGAGGTGAGCGAGGTGATCAAGATGGAAGACGGCTCCTACACCGTCCTCCTCATCTCCGACCGCAAGGCGGAGG
AGCTGAAGGGCTTCGCCCAGGTGGCCGAGGAGGCCCGGCAGGGAGCGGTCAACCGGAAGCGGAGCGAAAAGGCCCAGGCC
CTGATCCAGGCCCTGCGCGAGGAGGCGAAAATCGAGAACCGGCTGGCCGAGGTGCTGCAGGCCCTCACCCCCAAAACCCC
CTCCCAGGACCAACCCAACTCCCAGGAACAACCCCAGCCTGAAGAGGCCCCGGCCAACAACCCCTAA

Upstream 100 bases:

>100_bases
GAACCTCTGACCTTCGGCTCCGGAGGCCGACGCTCTATCCAGCTGAGCTACGGGCGCATACAGCAAGAGCTACTTTAGCA
CCCGCAAAGGAGGCAGTCAA

Downstream 100 bases:

>100_bases
CCCTGGGGCCCGGAGAGAAGGGGCGGGGGCTTCCCCGCCCTTTTACAATGGCCCCATGGAGATCACCCGGCTCCTCACCC
TCTACTACGAGGCGACCCCA

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 608; Mature: 608

Protein sequence:

>608_residues
MFGLSKRAITILFGLLALAFALGAILLFTPQAAQQTRGKPVLWVNGKALYELDLLRLQGNDPLYAASPEGLLKTLVDTYF
LEQVILTEALKQDAARVRVSSAEVRQEVNRIREQFGLKDKAAYEQFLNQVGYTDAQLRAEVKTQLQIQKRLEQIRSGAKP
TEEEVRFYYEVFKENYRTEPRVKARQIVVDDKALAEELAAKAKAGEDFAALARQHSKVGAEQGGALGAGPGEAEPKPVTQ
VVFPTEVGEAVFALKGPGVVGPIAAGGRYYIVKVEEYLPSTLPAFEEVKDRVAQDAERAKGNGVLEAYLEELRKKAQVRF
AEDNPYAYQNPPVAKVNEKEILLSEVLQPVFSNQQTVALVQQGLGELAVQFFLPQTLENLIDRELLVEAARKSGKPFIGS
KAEIAEAYLRYETRDVTASEEEARAFYSENPALFTVPASAKVIGVNFKEEAQAKAFRAAALRGGDLEALAKAQEGTVTDY
GTVNPNQLPAVLDRLVFKITETFPQGPLGEVSEVIKMEDGSYTVLLISDRKAEELKGFAQVAEEARQGAVNRKRSEKAQA
LIQALREEAKIENRLAEVLQALTPKTPSQDQPNSQEQPQPEEAPANNP

Sequences:

>Translated_608_residues
MFGLSKRAITILFGLLALAFALGAILLFTPQAAQQTRGKPVLWVNGKALYELDLLRLQGNDPLYAASPEGLLKTLVDTYF
LEQVILTEALKQDAARVRVSSAEVRQEVNRIREQFGLKDKAAYEQFLNQVGYTDAQLRAEVKTQLQIQKRLEQIRSGAKP
TEEEVRFYYEVFKENYRTEPRVKARQIVVDDKALAEELAAKAKAGEDFAALARQHSKVGAEQGGALGAGPGEAEPKPVTQ
VVFPTEVGEAVFALKGPGVVGPIAAGGRYYIVKVEEYLPSTLPAFEEVKDRVAQDAERAKGNGVLEAYLEELRKKAQVRF
AEDNPYAYQNPPVAKVNEKEILLSEVLQPVFSNQQTVALVQQGLGELAVQFFLPQTLENLIDRELLVEAARKSGKPFIGS
KAEIAEAYLRYETRDVTASEEEARAFYSENPALFTVPASAKVIGVNFKEEAQAKAFRAAALRGGDLEALAKAQEGTVTDY
GTVNPNQLPAVLDRLVFKITETFPQGPLGEVSEVIKMEDGSYTVLLISDRKAEELKGFAQVAEEARQGAVNRKRSEKAQA
LIQALREEAKIENRLAEVLQALTPKTPSQDQPNSQEQPQPEEAPANNP
>Mature_608_residues
MFGLSKRAITILFGLLALAFALGAILLFTPQAAQQTRGKPVLWVNGKALYELDLLRLQGNDPLYAASPEGLLKTLVDTYF
LEQVILTEALKQDAARVRVSSAEVRQEVNRIREQFGLKDKAAYEQFLNQVGYTDAQLRAEVKTQLQIQKRLEQIRSGAKP
TEEEVRFYYEVFKENYRTEPRVKARQIVVDDKALAEELAAKAKAGEDFAALARQHSKVGAEQGGALGAGPGEAEPKPVTQ
VVFPTEVGEAVFALKGPGVVGPIAAGGRYYIVKVEEYLPSTLPAFEEVKDRVAQDAERAKGNGVLEAYLEELRKKAQVRF
AEDNPYAYQNPPVAKVNEKEILLSEVLQPVFSNQQTVALVQQGLGELAVQFFLPQTLENLIDRELLVEAARKSGKPFIGS
KAEIAEAYLRYETRDVTASEEEARAFYSENPALFTVPASAKVIGVNFKEEAQAKAFRAAALRGGDLEALAKAQEGTVTDY
GTVNPNQLPAVLDRLVFKITETFPQGPLGEVSEVIKMEDGSYTVLLISDRKAEELKGFAQVAEEARQGAVNRKRSEKAQA
LIQALREEAKIENRLAEVLQALTPKTPSQDQPNSQEQPQPEEAPANNP

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF05698 Trigger_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 66912; Mature: 66912

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGLSKRAITILFGLLALAFALGAILLFTPQAAQQTRGKPVLWVNGKALYELDLLRLQGN
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCEEEEEEEEEECCC
DPLYAASPEGLLKTLVDTYFLEQVILTEALKQDAARVRVSSAEVRQEVNRIREQFGLKDK
CCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AAYEQFLNQVGYTDAQLRAEVKTQLQIQKRLEQIRSGAKPTEEEVRFYYEVFKENYRTEP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC
RVKARQIVVDDKALAEELAAKAKAGEDFAALARQHSKVGAEQGGALGAGPGEAEPKPVTQ
CHHHHHEEECHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCEE
VVFPTEVGEAVFALKGPGVVGPIAAGGRYYIVKVEEYLPSTLPAFEEVKDRVAQDAERAK
EECCHHHCCEEEEECCCCCCCCCCCCCEEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHC
GNGVLEAYLEELRKKAQVRFAEDNPYAYQNPPVAKVNEKEILLSEVLQPVFSNQQTVALV
CCCHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
QQGLGELAVQFFLPQTLENLIDRELLVEAARKSGKPFIGSKAEIAEAYLRYETRDVTASE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCH
EEARAFYSENPALFTVPASAKVIGVNFKEEAQAKAFRAAALRGGDLEALAKAQEGTVTDY
HHHHHHHCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCC
GTVNPNQLPAVLDRLVFKITETFPQGPLGEVSEVIKMEDGSYTVLLISDRKAEELKGFAQ
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHH
VAEEARQGAVNRKRSEKAQALIQALREEAKIENRLAEVLQALTPKTPSQDQPNSQEQPQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
EEAPANNP
CCCCCCCC
>Mature Secondary Structure
MFGLSKRAITILFGLLALAFALGAILLFTPQAAQQTRGKPVLWVNGKALYELDLLRLQGN
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCEEEEEEEEEECCC
DPLYAASPEGLLKTLVDTYFLEQVILTEALKQDAARVRVSSAEVRQEVNRIREQFGLKDK
CCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AAYEQFLNQVGYTDAQLRAEVKTQLQIQKRLEQIRSGAKPTEEEVRFYYEVFKENYRTEP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC
RVKARQIVVDDKALAEELAAKAKAGEDFAALARQHSKVGAEQGGALGAGPGEAEPKPVTQ
CHHHHHEEECHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCEE
VVFPTEVGEAVFALKGPGVVGPIAAGGRYYIVKVEEYLPSTLPAFEEVKDRVAQDAERAK
EECCHHHCCEEEEECCCCCCCCCCCCCEEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHC
GNGVLEAYLEELRKKAQVRFAEDNPYAYQNPPVAKVNEKEILLSEVLQPVFSNQQTVALV
CCCHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
QQGLGELAVQFFLPQTLENLIDRELLVEAARKSGKPFIGSKAEIAEAYLRYETRDVTASE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCH
EEARAFYSENPALFTVPASAKVIGVNFKEEAQAKAFRAAALRGGDLEALAKAQEGTVTDY
HHHHHHHCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCC
GTVNPNQLPAVLDRLVFKITETFPQGPLGEVSEVIKMEDGSYTVLLISDRKAEELKGFAQ
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHH
VAEEARQGAVNRKRSEKAQALIQALREEAKIENRLAEVLQALTPKTPSQDQPNSQEQPQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
EEAPANNP
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA