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The map label for this gene is lolC [H]

Identifier: 55980180

GI number: 55980180

Start: 207069

End: 208184

Strand: Reverse

Name: lolC [H]

Synonym: TTHA0211

Alternate gene names: 55980180

Gene position: 208184-207069 (Counterclockwise)

Preceding gene: 55980181

Following gene: 55980174

Centisome position: 11.25

GC content: 71.15

Gene sequence:

>1116_bases
GTGCGCTTCGCCCTCTTCCTCGCCTGGGCCCACATCTGGCGCCGCCCCCTTCAAAGCGCCCTCGCCGTCTTGGGCGTGGG
CGTGGGGGTGGGGGTGCTTTTGGTGGCCCTTTCCCTGGCCAACGGCTTCATGGACGGCCTCGTCCGGGCCACGCTCAAGG
CCTACCCCCAGCTCGTTCTCTTCAGCCTGGAGCCCACCCTTCCCCCCCTCCCTTCCCACCCGGAGGTGGAGGCGGCGGCC
CCCTTCGCCGCCACCAAGGCCCTCCTCACCCGGCCCGCCGAGGCGGGCCGGGGGCCCGGGGTGGACTTCGCCACCCTGGT
GGGGCTCGGTGCGGGCGGGGAGGCCCTTTACCCCGAGCTCGGGCTCAGGCTGGAGCCTGGGGGGATCTACCTGGGCGCGG
CCCTGATGCAGAGCCTGGACGCCCGGCCCGGGGACCGGCTCTACGCCCTTTCCGCCACGCAGGAGCGGGTGGAGCTCAAG
GTGCTCGGGAGCTTCCGCACAGGGAACTACCTCATTGACAGCGGCTTCGCCTTCACCGACCTGGAGAGCGTGAAGCGCCT
TTCCGGCCTCGAGGCCCAGGGGTACCAGGTGCGCTTAAAGGACCCCTGGCGGGCCCGGGAGGTGGGGTGGGCCCTGGCGG
GAAGCCGCTTCTTCCCCCAGCCCTGGCAGGACACCCAGCGCACCCTCTTGGAGCAGCTTTCCCTGCAGCGGCAGGTCCTC
GGCCTTTTGATCTTCCTCATCGTGGCCGTGGCCGCCCTTGGGGTGGCCAACCTCCTCTTCCTCAAGGTGGTGGAGAAGAC
CCCGGAGATCGCCCTCCTCCGGGCCATGGGGGCCTCGAGGGGGACCGTGGGCCTGGTCTTCGCCCTGGAGGGGGCGATCC
TTGGGGTGGGGGGCGTGGCCTTGGGCAACCTCCTCGGCTACCTCCTCGGCCTCTACCTGGCCCGCCGCCCCCTGGACCTC
CCCGGGGAGCTCTACTTCCTCACCCACCTCCCCGTGGAGATGCGCCTCGCCGACTTCCTCTGGGTAAGCGGGGCGAGCCT
TCTCGCCGTCCTCCTCTCCGCCCTTCTTCCCCTTCTCCGGGCCCTAAGGGTGCGGCCCGGGGTTGTCCTGCGCTAA

Upstream 100 bases:

>100_bases
CTGGTTCCCTGACCGGGCCACGGCCCTCCGCTTTGGCCGCCGCAAGGTCCAGCTGGAGGTGGTGGCCTACCCCGAGTAAG
GGCGAGCGTATCCTGAAGGC

Downstream 100 bases:

>100_bases
AGGAAAACCCGGGCCCCACATGGCCCGGGGGCACCCCGCAGGGCGGCGGTTACTTGAGCTCCACCACCGCGCCCACGGCC
TCGAGCTTCTTCTTGATCTC

Product: lipoprotein releasing system transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MRFALFLAWAHIWRRPLQSALAVLGVGVGVGVLLVALSLANGFMDGLVRATLKAYPQLVLFSLEPTLPPLPSHPEVEAAA
PFAATKALLTRPAEAGRGPGVDFATLVGLGAGGEALYPELGLRLEPGGIYLGAALMQSLDARPGDRLYALSATQERVELK
VLGSFRTGNYLIDSGFAFTDLESVKRLSGLEAQGYQVRLKDPWRAREVGWALAGSRFFPQPWQDTQRTLLEQLSLQRQVL
GLLIFLIVAVAALGVANLLFLKVVEKTPEIALLRAMGASRGTVGLVFALEGAILGVGGVALGNLLGYLLGLYLARRPLDL
PGELYFLTHLPVEMRLADFLWVSGASLLAVLLSALLPLLRALRVRPGVVLR

Sequences:

>Translated_371_residues
MRFALFLAWAHIWRRPLQSALAVLGVGVGVGVLLVALSLANGFMDGLVRATLKAYPQLVLFSLEPTLPPLPSHPEVEAAA
PFAATKALLTRPAEAGRGPGVDFATLVGLGAGGEALYPELGLRLEPGGIYLGAALMQSLDARPGDRLYALSATQERVELK
VLGSFRTGNYLIDSGFAFTDLESVKRLSGLEAQGYQVRLKDPWRAREVGWALAGSRFFPQPWQDTQRTLLEQLSLQRQVL
GLLIFLIVAVAALGVANLLFLKVVEKTPEIALLRAMGASRGTVGLVFALEGAILGVGGVALGNLLGYLLGLYLARRPLDL
PGELYFLTHLPVEMRLADFLWVSGASLLAVLLSALLPLLRALRVRPGVVLR
>Mature_371_residues
MRFALFLAWAHIWRRPLQSALAVLGVGVGVGVLLVALSLANGFMDGLVRATLKAYPQLVLFSLEPTLPPLPSHPEVEAAA
PFAATKALLTRPAEAGRGPGVDFATLVGLGAGGEALYPELGLRLEPGGIYLGAALMQSLDARPGDRLYALSATQERVELK
VLGSFRTGNYLIDSGFAFTDLESVKRLSGLEAQGYQVRLKDPWRAREVGWALAGSRFFPQPWQDTQRTLLEQLSLQRQVL
GLLIFLIVAVAALGVANLLFLKVVEKTPEIALLRAMGASRGTVGLVFALEGAILGVGGVALGNLLGYLLGLYLARRPLDL
PGELYFLTHLPVEMRLADFLWVSGASLLAVLLSALLPLLRALRVRPGVVLR

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=322, Percent_Identity=28.2608695652174, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 39797; Mature: 39797

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFALFLAWAHIWRRPLQSALAVLGVGVGVGVLLVALSLANGFMDGLVRATLKAYPQLVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
FSLEPTLPPLPSHPEVEAAAPFAATKALLTRPAEAGRGPGVDFATLVGLGAGGEALYPEL
EEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHCCCCCCCCHHHHHCCCCCCCCCCCCC
GLRLEPGGIYLGAALMQSLDARPGDRLYALSATQERVELKVLGSFRTGNYLIDSGFAFTD
CCEECCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHEEEEEEECCCCCCEEEECCCCHHH
LESVKRLSGLEAQGYQVRLKDPWRAREVGWALAGSRFFPQPWQDTQRTLLEQLSLQRQVL
HHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
GLLIFLIVAVAALGVANLLFLKVVEKTPEIALLRAMGASRGTVGLVFALEGAILGVGGVA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEECCHHHCCHHHH
LGNLLGYLLGLYLARRPLDLPGELYFLTHLPVEMRLADFLWVSGASLLAVLLSALLPLLR
HHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALRVRPGVVLR
HHHCCCCCCCC
>Mature Secondary Structure
MRFALFLAWAHIWRRPLQSALAVLGVGVGVGVLLVALSLANGFMDGLVRATLKAYPQLVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
FSLEPTLPPLPSHPEVEAAAPFAATKALLTRPAEAGRGPGVDFATLVGLGAGGEALYPEL
EEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHCCCCCCCCHHHHHCCCCCCCCCCCCC
GLRLEPGGIYLGAALMQSLDARPGDRLYALSATQERVELKVLGSFRTGNYLIDSGFAFTD
CCEECCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHEEEEEEECCCCCCEEEECCCCHHH
LESVKRLSGLEAQGYQVRLKDPWRAREVGWALAGSRFFPQPWQDTQRTLLEQLSLQRQVL
HHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
GLLIFLIVAVAALGVANLLFLKVVEKTPEIALLRAMGASRGTVGLVFALEGAILGVGGVA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEECCHHHCCHHHH
LGNLLGYLLGLYLARRPLDLPGELYFLTHLPVEMRLADFLWVSGASLLAVLLSALLPLLR
HHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALRVRPGVVLR
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]