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The map label for this gene is lolD [H]

Identifier: 55980083

GI number: 55980083

Start: 113326

End: 115083

Strand: Reverse

Name: lolD [H]

Synonym: TTHA0114

Alternate gene names: 55980083

Gene position: 115083-113326 (Counterclockwise)

Preceding gene: 55980084

Following gene: 55980081

Centisome position: 6.22

GC content: 70.25

Gene sequence:

>1758_bases
ATGGGGTACCATGGGGGCACGATGCGCGTCTTGGGGCGGAGGATCTACTGGCGCTGGTACGGGGAGGTCCTCCTGGAGGG
GGGCGTGACCTTGCGCATGACCGGGGACGTGGCCAAGTGGCTGAGGCCCGGGGATAGGGTGAGGCTTCGCACCGAGTTCA
AGAAGCCCGTCCTCGGCTTTGACGAGTACGCCCTCGAGGCCGCCTTCCCCCTCTGGCCCCCCTTCGCCAAGACCCTGGAG
CACGTGCGGGAAAGCCCCTTTGGGGGCGAGGCCTACCGCTACCGCCTGAAGGTGCGGGAGGCCACCTACGAGGGGGATTA
CGAGGCCATCGCCGAGCTGGAGCAGTTCCACTACGCCTCGGAGAAGGAGGTGGTGGCCCTCTGGGTCTGCACCCAGTGCC
AGAAGACCCTCCCCGCCAACGCCAGGCCCCTCTGCGACTGCGGCGGGGAGGCGAGGCTTAAAGAGATCCGGGGCTCCACC
CCGGCGAGCCGCTTTCTGGTGCTGGAGCTTGCGGAGCGCCTCCCCTTTGAGCCCAGGATCCTGGGCTACCTCCGCCTAGA
CCCCCCTATCCCCCGGATGCACCGAAGGACCCCCGAGGGCGTGGAGCGGGACATCCGGGAAAGGATCTTCCCCCGGGACT
GGTTCCACCCCACTTACGAGGGCGGGGCGGACTGGCAGAGGGCCCTGGACCGGGTGAACACCGCTGCCGCCCGCATCGCC
CGGGTGGTGGTCCACCCCGACTACCGCTCCGAGGGGTTTGGGGCCCTTCTCGTGCGGGTGGCCCTGGAGTGGGCGAAGGA
GCGGGGGGCGCCTGAAGCCAGGCGGGAGAAGCACCTCGTCTACACCATCGCCCAGATGGCCCGCTACCACCCCTTCTTTG
AGAAGGTGGGGTTCCGCTACCTCTTTGACACCGCCTCGGGAAGGCCCGTCCTCTTCTACCCCCTCACGGAGGAGGCCGAG
GCCCACCTGGAGCGCTTCCTCCGGGAGGACCCCTACGCCAAGGCCCACGGGGGAAGGCTCTATAAGCCCCGGTTCGGGCG
GGTCCCGGGGCTTCCTGGCCCGATCCGCCTGAGGGGCGTCCACAAGGCCTACCGGAGCCACCTGGACCTAGAGGGCCTTT
CCCGGGAGGTTCAGGAGGCCCTCCTCGCCTTCGGGGTGAAGGCCCGGGTGGTGGAGCGGGCGGTGCTCCGGGGGGCGAGC
CTGGAGATCCCCCCGGGAAGCCTCGTGGTCCTGGCGGGGGCGAGCGGGGCGGGGAAGACCACCCTCCTAAGGCTGCTCCT
TGGCGAGGCGCCGGATGCCGGGGAGGTGGCGGTGCCCCCGGGGAGGCGGGTGGCCTACATCCCGGGGGAGAGGGAGGTGG
ACCTGGGGGAGGACCCCATCCTCGAGGCCGTTTACCGGAGGCTAAAGGACGTGGGGGCGGCCATAGAGGTGCTGAACCGG
GTGGGCCTCTCCGACGCCGTGCTTTACCGGGCAAGGCCCCATGAGCTTTCCACCGGGCAGAGGGAGCGCTTCCGCTTGGC
CCTCCTCCTCGCGGAAAGGCCCGACCTCCTCCTCATAGACGAGTTCGCCGCCCACCTGGACGTGCCCACGGCGCGGCGGG
TGGCCCTGGGCCTGGGGAAGCTCTGCCGGGAGGCGGGGGTCACCCTGGTGGCCGCCACCCACCGGCCCGAGGTGGTGGCC
GCCCTGGACCCCGACCTCCTCGTCTACGTGGGCTACGGGGGGCTTACCACCGTACCTCGGAGAGGTCCACGAACATGA

Upstream 100 bases:

>100_bases
CGGCAGGCCCTCCGCCTACGGCAAGCGGGTGGTCTTCGCCAAGGCGTACTGAGGGGGAAGGGCGCTTCCGGGGCGCCCCT
CGAGGGGCGCCCCGCGCCTT

Downstream 100 bases:

>100_bases
CCCGGCCCGGGCGCCTGGGCACGTGGAGGGGCTTCTCGTAGCGGAAGGCGTTTTCCAGGACCCAGGCGTAGAGGGGCTCG
TCCTTGGCGTAGGCCCGGAG

Product: ABC transporter ATP-binding protein

Products: ADP; phosphate; putrescine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 584

Protein sequence:

>585_residues
MGYHGGTMRVLGRRIYWRWYGEVLLEGGVTLRMTGDVAKWLRPGDRVRLRTEFKKPVLGFDEYALEAAFPLWPPFAKTLE
HVRESPFGGEAYRYRLKVREATYEGDYEAIAELEQFHYASEKEVVALWVCTQCQKTLPANARPLCDCGGEARLKEIRGST
PASRFLVLELAERLPFEPRILGYLRLDPPIPRMHRRTPEGVERDIRERIFPRDWFHPTYEGGADWQRALDRVNTAAARIA
RVVVHPDYRSEGFGALLVRVALEWAKERGAPEARREKHLVYTIAQMARYHPFFEKVGFRYLFDTASGRPVLFYPLTEEAE
AHLERFLREDPYAKAHGGRLYKPRFGRVPGLPGPIRLRGVHKAYRSHLDLEGLSREVQEALLAFGVKARVVERAVLRGAS
LEIPPGSLVVLAGASGAGKTTLLRLLLGEAPDAGEVAVPPGRRVAYIPGEREVDLGEDPILEAVYRRLKDVGAAIEVLNR
VGLSDAVLYRARPHELSTGQRERFRLALLLAERPDLLLIDEFAAHLDVPTARRVALGLGKLCREAGVTLVAATHRPEVVA
ALDPDLLVYVGYGGLTTVPRRGPRT

Sequences:

>Translated_585_residues
MGYHGGTMRVLGRRIYWRWYGEVLLEGGVTLRMTGDVAKWLRPGDRVRLRTEFKKPVLGFDEYALEAAFPLWPPFAKTLE
HVRESPFGGEAYRYRLKVREATYEGDYEAIAELEQFHYASEKEVVALWVCTQCQKTLPANARPLCDCGGEARLKEIRGST
PASRFLVLELAERLPFEPRILGYLRLDPPIPRMHRRTPEGVERDIRERIFPRDWFHPTYEGGADWQRALDRVNTAAARIA
RVVVHPDYRSEGFGALLVRVALEWAKERGAPEARREKHLVYTIAQMARYHPFFEKVGFRYLFDTASGRPVLFYPLTEEAE
AHLERFLREDPYAKAHGGRLYKPRFGRVPGLPGPIRLRGVHKAYRSHLDLEGLSREVQEALLAFGVKARVVERAVLRGAS
LEIPPGSLVVLAGASGAGKTTLLRLLLGEAPDAGEVAVPPGRRVAYIPGEREVDLGEDPILEAVYRRLKDVGAAIEVLNR
VGLSDAVLYRARPHELSTGQRERFRLALLLAERPDLLLIDEFAAHLDVPTARRVALGLGKLCREAGVTLVAATHRPEVVA
ALDPDLLVYVGYGGLTTVPRRGPRT
>Mature_584_residues
GYHGGTMRVLGRRIYWRWYGEVLLEGGVTLRMTGDVAKWLRPGDRVRLRTEFKKPVLGFDEYALEAAFPLWPPFAKTLEH
VRESPFGGEAYRYRLKVREATYEGDYEAIAELEQFHYASEKEVVALWVCTQCQKTLPANARPLCDCGGEARLKEIRGSTP
ASRFLVLELAERLPFEPRILGYLRLDPPIPRMHRRTPEGVERDIRERIFPRDWFHPTYEGGADWQRALDRVNTAAARIAR
VVVHPDYRSEGFGALLVRVALEWAKERGAPEARREKHLVYTIAQMARYHPFFEKVGFRYLFDTASGRPVLFYPLTEEAEA
HLERFLREDPYAKAHGGRLYKPRFGRVPGLPGPIRLRGVHKAYRSHLDLEGLSREVQEALLAFGVKARVVERAVLRGASL
EIPPGSLVVLAGASGAGKTTLLRLLLGEAPDAGEVAVPPGRRVAYIPGEREVDLGEDPILEAVYRRLKDVGAAIEVLNRV
GLSDAVLYRARPHELSTGQRERFRLALLLAERPDLLLIDEFAAHLDVPTARRVALGLGKLCREAGVTLVAATHRPEVVAA
LDPDLLVYVGYGGLTTVPRRGPRT

Specific function: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-de

COG id: COG2401

COG function: function code R; ABC-type ATPase fused to a predicted acetyltransferase domain

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI87081791, Length=173, Percent_Identity=35.2601156069364, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787370, Length=194, Percent_Identity=29.8969072164948, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790467, Length=220, Percent_Identity=30, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787712, Length=174, Percent_Identity=32.183908045977, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1787164, Length=216, Percent_Identity=35.1851851851852, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789751, Length=154, Percent_Identity=34.4155844155844, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788165, Length=178, Percent_Identity=30.8988764044944, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1786563, Length=187, Percent_Identity=30.4812834224599, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015854
- InterPro:   IPR003593
- InterPro:   IPR011924 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 65843; Mature: 65712

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYHGGTMRVLGRRIYWRWYGEVLLEGGVTLRMTGDVAKWLRPGDRVRLRTEFKKPVLGF
CCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHCCCCCCEEEEEHHCCCCCCC
DEYALEAAFPLWPPFAKTLEHVRESPFGGEAYRYRLKVREATYEGDYEAIAELEQFHYAS
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHCCC
EKEVVALWVCTQCQKTLPANARPLCDCGGEARLKEIRGSTPASRFLVLELAERLPFEPRI
CCCEEEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCE
LGYLRLDPPIPRMHRRTPEGVERDIRERIFPRDWFHPTYEGGADWQRALDRVNTAAARIA
EEEEECCCCCCHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RVVVHPDYRSEGFGALLVRVALEWAKERGAPEARREKHLVYTIAQMARYHPFFEKVGFRY
HEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHCCCEE
LFDTASGRPVLFYPLTEEAEAHLERFLREDPYAKAHGGRLYKPRFGRVPGLPGPIRLRGV
EEECCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCEEEHHH
HKAYRSHLDLEGLSREVQEALLAFGVKARVVERAVLRGASLEIPPGSLVVLAGASGAGKT
HHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHH
TLLRLLLGEAPDAGEVAVPPGRRVAYIPGEREVDLGEDPILEAVYRRLKDVGAAIEVLNR
HHHHHHHCCCCCCCCEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VGLSDAVLYRARPHELSTGQRERFRLALLLAERPDLLLIDEFAAHLDVPTARRVALGLGK
CCCCHHHEEECCCCCCCCCCHHHEEEEEEEECCCCEEEEEHHHHHCCCCHHHHHHHHHHH
LCREAGVTLVAATHRPEVVAALDPDLLVYVGYGGLTTVPRRGPRT
HHHHCCCEEEEECCCCCEEEECCCCEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
GYHGGTMRVLGRRIYWRWYGEVLLEGGVTLRMTGDVAKWLRPGDRVRLRTEFKKPVLGF
CCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHCCCCCCEEEEEHHCCCCCCC
DEYALEAAFPLWPPFAKTLEHVRESPFGGEAYRYRLKVREATYEGDYEAIAELEQFHYAS
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHCCC
EKEVVALWVCTQCQKTLPANARPLCDCGGEARLKEIRGSTPASRFLVLELAERLPFEPRI
CCCEEEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCE
LGYLRLDPPIPRMHRRTPEGVERDIRERIFPRDWFHPTYEGGADWQRALDRVNTAAARIA
EEEEECCCCCCHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RVVVHPDYRSEGFGALLVRVALEWAKERGAPEARREKHLVYTIAQMARYHPFFEKVGFRY
HEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHCCCEE
LFDTASGRPVLFYPLTEEAEAHLERFLREDPYAKAHGGRLYKPRFGRVPGLPGPIRLRGV
EEECCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCEEEHHH
HKAYRSHLDLEGLSREVQEALLAFGVKARVVERAVLRGASLEIPPGSLVVLAGASGAGKT
HHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHH
TLLRLLLGEAPDAGEVAVPPGRRVAYIPGEREVDLGEDPILEAVYRRLKDVGAAIEVLNR
HHHHHHHCCCCCCCCEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VGLSDAVLYRARPHELSTGQRERFRLALLLAERPDLLLIDEFAAHLDVPTARRVALGLGK
CCCCHHHEEECCCCCCCCCCHHHEEEEEEEECCCCEEEEEHHHHHCCCCHHHHHHHHHHH
LCREAGVTLVAATHRPEVVAALDPDLLVYVGYGGLTTVPRRGPRT
HHHHCCCEEEEECCCCCEEEECCCCEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; putrescine [Periplasm]; H2O [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA