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The map label for this gene is glcD [H]

Identifier: 55980009

GI number: 55980009

Start: 41137

End: 42486

Strand: Direct

Name: glcD [H]

Synonym: TTHA0040

Alternate gene names: 55980009

Gene position: 41137-42486 (Clockwise)

Preceding gene: 55980008

Following gene: 55980012

Centisome position: 2.22

GC content: 68.59

Gene sequence:

>1350_bases
ATGGAAAAGCTGGAAGCCCTGAAGCGCCTCTTCCCGGGGAAGGTGGACCTCTCGGAAAGCGAGCGCCTGCGCCACGGCAA
AGACGAGGGCTACCCCGAGGCGAGGCCCGTGTTGGCCGTGGTCTACCCGGAGGGCGTGGAGGACGTGCAGAAGGCCCTCC
GTTGGGCACGGGAATGGGGCGTGGCGGTGATCCCCTTCGGGGCGGGGACGAGCCTCGAGGGCCACCTCTACCCCGTCAGG
GAGGCCATCAGCCTGGACCTGAGCCGGATGAACCGGGTCCTGGAGGTGAGGCCCCAGGACTTCTCTTGCGTGGTGGAGCC
CGGCCTCACCCGCAAGGCCTTAAACGAGGCCCTGAAGGGCACGGGCCTCTTCTTCCCCGTGGACCCGGGGGCGGACGCCT
CCTTGGGCGGCATGGCGGCCACGAACGCCAGCGGCACCACCACGGTGCGCTACGGAGGGATGCGGCAGAACGTCCTCGCC
CTCCAGGTGGTCCTGGCAAGCGGCGAGGTCTTAGAGCTCGGGCGGGGCGTGCGCAAGACCTCCTCGGGCTACGACCTCAA
GGACCTTTTCATTGGCTCGGAGGGCACCTTAGGGGTCATCACCCGCCTCACCCTTAGGCTCCACCCCCTCCCCGAGCACG
TCCACACCTTAAGGGTCTTCTTCCCCGGGGTGGAGGAGGCGGCGGAGGCGAGCTACCGGATCATGGCCTCCGGGCTTCCC
GTGGCGAGGCTGGAACTTTTGGACGAGCTCGCCATGCGGGCGCTAAACCGGTACCTAAAGGCGGGCTTCCCCGAGCGGCC
CGCCCTCTTCCTGGAGTTCCACGCCTCCACCAAGGAGGCCCTGGAGGCGGAGAGGGCCTCGGCCCTGGAGCTCGTGCGGG
AGGCCGGGGCCCTCGAGGTGGAGGCGGCCACAACGGAGGAGGAGAGGCGCCGCCAGTGGGAAGCCCGGCACCAGGCCTAC
TGGGCCCTCGTCCACCTCTTCCCCGGCCACCGCTTCATGATCACCGACACCGCCGTCCCCCTCTCCCGGCTTCCCGAGAT
GGTGCGCTTCGCCCAAGGGCTTCTAAGGGAGATGGGCCTCACCGGGAACATCCTGGGCCACGTGGGGGACGGGAACTTCC
ACACCCTAATTCCCGTCCTCCCCGAGGACTACCCCAAGGCCGAGGCCTACGCCGAGAGGCTCGTGGAAAAGGCCCTGGAG
CTTGGGGGCACCTGCACCGCCGAGCACGGGGTGGGCCTCCGCAAAAGGAAGTTCCTCCCCAAGGAGCACGGCCCCGCCCT
GGAGTGGATGCGGAGGCTCAAGGCCCTCTTTGACCCCGAAGGGCTCCTGAACCCGGGTAAGGTCGTCTAG

Upstream 100 bases:

>100_bases
GCGGGGGTGGCCCTCCCCCTCCCCTTCCTCTTGGCCGGGGGGCTCCTCCTCGGCTTCGCGGCCCTTTTGGGGAGGCGAAG
GGCGGCGTAAACTCAAGGGC

Downstream 100 bases:

>100_bases
GGAAGGCCGAAGAAGGCCCGGGCCCGGCGGAGGAGCTCCTCCCCCTCCAGGCCCTGGAAGAGGAAGGCGCTCCGGTCGGG
CTCCCCCTCCCAGACCTCGA

Product: FAD/FMN-containing dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MEKLEALKRLFPGKVDLSESERLRHGKDEGYPEARPVLAVVYPEGVEDVQKALRWAREWGVAVIPFGAGTSLEGHLYPVR
EAISLDLSRMNRVLEVRPQDFSCVVEPGLTRKALNEALKGTGLFFPVDPGADASLGGMAATNASGTTTVRYGGMRQNVLA
LQVVLASGEVLELGRGVRKTSSGYDLKDLFIGSEGTLGVITRLTLRLHPLPEHVHTLRVFFPGVEEAAEASYRIMASGLP
VARLELLDELAMRALNRYLKAGFPERPALFLEFHASTKEALEAERASALELVREAGALEVEAATTEEERRRQWEARHQAY
WALVHLFPGHRFMITDTAVPLSRLPEMVRFAQGLLREMGLTGNILGHVGDGNFHTLIPVLPEDYPKAEAYAERLVEKALE
LGGTCTAEHGVGLRKRKFLPKEHGPALEWMRRLKALFDPEGLLNPGKVV

Sequences:

>Translated_449_residues
MEKLEALKRLFPGKVDLSESERLRHGKDEGYPEARPVLAVVYPEGVEDVQKALRWAREWGVAVIPFGAGTSLEGHLYPVR
EAISLDLSRMNRVLEVRPQDFSCVVEPGLTRKALNEALKGTGLFFPVDPGADASLGGMAATNASGTTTVRYGGMRQNVLA
LQVVLASGEVLELGRGVRKTSSGYDLKDLFIGSEGTLGVITRLTLRLHPLPEHVHTLRVFFPGVEEAAEASYRIMASGLP
VARLELLDELAMRALNRYLKAGFPERPALFLEFHASTKEALEAERASALELVREAGALEVEAATTEEERRRQWEARHQAY
WALVHLFPGHRFMITDTAVPLSRLPEMVRFAQGLLREMGLTGNILGHVGDGNFHTLIPVLPEDYPKAEAYAERLVEKALE
LGGTCTAEHGVGLRKRKFLPKEHGPALEWMRRLKALFDPEGLLNPGKVV
>Mature_449_residues
MEKLEALKRLFPGKVDLSESERLRHGKDEGYPEARPVLAVVYPEGVEDVQKALRWAREWGVAVIPFGAGTSLEGHLYPVR
EAISLDLSRMNRVLEVRPQDFSCVVEPGLTRKALNEALKGTGLFFPVDPGADASLGGMAATNASGTTTVRYGGMRQNVLA
LQVVLASGEVLELGRGVRKTSSGYDLKDLFIGSEGTLGVITRLTLRLHPLPEHVHTLRVFFPGVEEAAEASYRIMASGLP
VARLELLDELAMRALNRYLKAGFPERPALFLEFHASTKEALEAERASALELVREAGALEVEAATTEEERRRQWEARHQAY
WALVHLFPGHRFMITDTAVPLSRLPEMVRFAQGLLREMGLTGNILGHVGDGNFHTLIPVLPEDYPKAEAYAERLVEKALE
LGGTCTAEHGVGLRKRKFLPKEHGPALEWMRRLKALFDPEGLLNPGKVV

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=454, Percent_Identity=49.3392070484581, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI37595754, Length=477, Percent_Identity=47.1698113207547, Blast_Score=404, Evalue=1e-112,
Organism=Homo sapiens, GI119964728, Length=466, Percent_Identity=32.618025751073, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI4501993, Length=260, Percent_Identity=31.5384615384615, Blast_Score=112, Evalue=5e-25,
Organism=Escherichia coli, GI1789351, Length=457, Percent_Identity=32.6039387308534, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1787977, Length=519, Percent_Identity=27.9383429672447, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI48994907, Length=201, Percent_Identity=26.865671641791, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994914, Length=169, Percent_Identity=27.810650887574, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71992373, Length=443, Percent_Identity=40.6320541760722, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI71992381, Length=444, Percent_Identity=39.4144144144144, Blast_Score=348, Evalue=4e-96,
Organism=Caenorhabditis elegans, GI71992392, Length=361, Percent_Identity=43.213296398892, Blast_Score=330, Evalue=8e-91,
Organism=Caenorhabditis elegans, GI17534361, Length=452, Percent_Identity=27.212389380531, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17556096, Length=474, Percent_Identity=21.9409282700422, Blast_Score=104, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6320027, Length=431, Percent_Identity=34.1067285382831, Blast_Score=273, Evalue=6e-74,
Organism=Saccharomyces cerevisiae, GI6320023, Length=438, Percent_Identity=29.4520547945205, Blast_Score=169, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6320764, Length=433, Percent_Identity=28.175519630485, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI18921117, Length=430, Percent_Identity=30.4651162790698, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24639277, Length=430, Percent_Identity=30.4651162790698, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24639275, Length=430, Percent_Identity=30.4651162790698, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24653753, Length=193, Percent_Identity=34.1968911917098, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 49585; Mature: 49585

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLEALKRLFPGKVDLSESERLRHGKDEGYPEARPVLAVVYPEGVEDVQKALRWAREWG
CCHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCC
VAVIPFGAGTSLEGHLYPVREAISLDLSRMNRVLEVRPQDFSCVVEPGLTRKALNEALKG
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCCCHHHHHHHHHC
TGLFFPVDPGADASLGGMAATNASGTTTVRYGGMRQNVLALQVVLASGEVLELGRGVRKT
CCEEEECCCCCCCCCCCCEECCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHCCCCCCC
SSGYDLKDLFIGSEGTLGVITRLTLRLHPLPEHVHTLRVFFPGVEEAAEASYRIMASGLP
CCCCCHHHEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHCEEEEECCCC
VARLELLDELAMRALNRYLKAGFPERPALFLEFHASTKEALEAERASALELVREAGALEV
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEE
EAATTEEERRRQWEARHQAYWALVHLFPGHRFMITDTAVPLSRLPEMVRFAQGLLREMGL
EECCCHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCC
TGNILGHVGDGNFHTLIPVLPEDYPKAEAYAERLVEKALELGGTCTAEHGVGLRKRKFLP
CCCEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEHHCCCCCHHHHCCC
KEHGPALEWMRRLKALFDPEGLLNPGKVV
CCCCCHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MEKLEALKRLFPGKVDLSESERLRHGKDEGYPEARPVLAVVYPEGVEDVQKALRWAREWG
CCHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCC
VAVIPFGAGTSLEGHLYPVREAISLDLSRMNRVLEVRPQDFSCVVEPGLTRKALNEALKG
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCCCHHHHHHHHHC
TGLFFPVDPGADASLGGMAATNASGTTTVRYGGMRQNVLALQVVLASGEVLELGRGVRKT
CCEEEECCCCCCCCCCCCEECCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHCCCCCCC
SSGYDLKDLFIGSEGTLGVITRLTLRLHPLPEHVHTLRVFFPGVEEAAEASYRIMASGLP
CCCCCHHHEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHCEEEEECCCC
VARLELLDELAMRALNRYLKAGFPERPALFLEFHASTKEALEAERASALELVREAGALEV
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEE
EAATTEEERRRQWEARHQAYWALVHLFPGHRFMITDTAVPLSRLPEMVRFAQGLLREMGL
EECCCHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCC
TGNILGHVGDGNFHTLIPVLPEDYPKAEAYAERLVEKALELGGTCTAEHGVGLRKRKFLP
CCCEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEHHCCCCCHHHHCCC
KEHGPALEWMRRLKALFDPEGLLNPGKVV
CCCCCHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]