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The map label for this gene is dnaN [H]

Identifier: 55979970

GI number: 55979970

Start: 55

End: 1182

Strand: Direct

Name: dnaN [H]

Synonym: TTHA0001

Alternate gene names: 55979970

Gene position: 55-1182 (Clockwise)

Preceding gene: NA

Following gene: 55979971

Centisome position: 0.0

GC content: 71.45

Gene sequence:

>1128_bases
ATGAACATAACGGTTCCCAAAAAACTCCTCTCGGACCAGCTTTCCCTCCTGGAGCGCATCGTCCCCTCTAGAAGCGCCAA
CCCCCTCTACACCTACCTGGGGCTTTACGCCGAGGAAGGGGCCTTGATCCTCTTCGGGACCAACGGGGAGGTGGACCTCG
AGGTCCGCCTCCCCGCCGAGGCCCAAAGCCTTCCCCGGGTGCTCGTCCCCGCCCAGCCCTTCTTCCAGCTGGTGCGGAGC
CTTCCTGGGGACCTCGTGGCCCTCGGCCTCGCCTCGGAGCCGGGCCAGGGGGGGCAGCTGGAGCTCTCCTCCGGGCGCTT
CCGCACCCGGCTCAGCCTGGCCCCTGCCGAGGGCTACCCCGAGCTTCTGGTGCCCGAGGGGGAGGACAAGGGGGCCTTCC
CCCTCCGGACGCGGATGCCCTCCGGGGAGCTCGTCAAGGCCTTGACCCACGTGCGCTACGCCGCGAGCAACGAGGAGTAC
CGGGCCATCTTCCGCGGGGTGCAGCTGGAGTTCTCCCCCCAGGGCTTCCGGGCGGTGGCCTCCGACGGGTACCGCCTCGC
CCTCTACGACCTGCCCCTGCCCCAAGGGTTCCAGGCCAAGGCCGTGGTCCCCGCCCGGAGCGTGGACGAGATGGTGCGGG
TCCTGAAGGGGGCGGACGGGGCCGAGGCCGACCTCGCCCTGGGCGAGGGGGTGTTGGCCCTGGCCCTCGAGGGCGGAAGC
GGGGTCCGGATGGCCCTCCGCCTCATGGAAGGGGAGTTCCCCGACTACCAGAGGGTCATCCCCCAGGAGTTCGCCCTCAA
GGTCCAGGTGGAGGGGGAGGCCCTCAGGGAGGCGGTGCGCCGGGTGAGCGTCCTCTCCGACCGGCAGAACCACCGGGTGG
ACCTCCTTTTGGAGGAAGGCCGGATCCTCCTCTCCGCCGAGGGGGACTACGGCAAGGGGCAGGAGGAGGTGCCCGCCCAG
GTGGAGGGGCCGGGCATGGCCGTGGCCTACAACGCCCGCTACCTCCTCGAGGCCCTCGCCCCCGTGGGGGACCGGGCCCA
CCTGGGCATCTCCGGGCCCACGAGCCCGAGCCTCATCTGGGGGGACGGGGAGGGGTACCGGGCGGTGGTGGTGCCCCTCA
GGGTCTAG

Upstream 100 bases:

>100_bases
CCGCTTATCCACATTTCCACAGGCCCTACTACTACGACTACGGATCTTTTAAAAGCTTTAAAAAGAGAGTCGTAATAGCC
GTTAAAGGAGGCGTCGGGCA

Downstream 100 bases:

>100_bases
GGGGTAGTATGGGGTGGGGGAGCGTGAAGCGCTTCCACAAGGGAGGTTGGGCATGACCACCATCGTCGGCGTCCGGGCAC
GCGAGGTTTTGGATTCCAGG

Product: DNA polymerase III subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MNITVPKKLLSDQLSLLERIVPSRSANPLYTYLGLYAEEGALILFGTNGEVDLEVRLPAEAQSLPRVLVPAQPFFQLVRS
LPGDLVALGLASEPGQGGQLELSSGRFRTRLSLAPAEGYPELLVPEGEDKGAFPLRTRMPSGELVKALTHVRYAASNEEY
RAIFRGVQLEFSPQGFRAVASDGYRLALYDLPLPQGFQAKAVVPARSVDEMVRVLKGADGAEADLALGEGVLALALEGGS
GVRMALRLMEGEFPDYQRVIPQEFALKVQVEGEALREAVRRVSVLSDRQNHRVDLLLEEGRILLSAEGDYGKGQEEVPAQ
VEGPGMAVAYNARYLLEALAPVGDRAHLGISGPTSPSLIWGDGEGYRAVVVPLRV

Sequences:

>Translated_375_residues
MNITVPKKLLSDQLSLLERIVPSRSANPLYTYLGLYAEEGALILFGTNGEVDLEVRLPAEAQSLPRVLVPAQPFFQLVRS
LPGDLVALGLASEPGQGGQLELSSGRFRTRLSLAPAEGYPELLVPEGEDKGAFPLRTRMPSGELVKALTHVRYAASNEEY
RAIFRGVQLEFSPQGFRAVASDGYRLALYDLPLPQGFQAKAVVPARSVDEMVRVLKGADGAEADLALGEGVLALALEGGS
GVRMALRLMEGEFPDYQRVIPQEFALKVQVEGEALREAVRRVSVLSDRQNHRVDLLLEEGRILLSAEGDYGKGQEEVPAQ
VEGPGMAVAYNARYLLEALAPVGDRAHLGISGPTSPSLIWGDGEGYRAVVVPLRV
>Mature_375_residues
MNITVPKKLLSDQLSLLERIVPSRSANPLYTYLGLYAEEGALILFGTNGEVDLEVRLPAEAQSLPRVLVPAQPFFQLVRS
LPGDLVALGLASEPGQGGQLELSSGRFRTRLSLAPAEGYPELLVPEGEDKGAFPLRTRMPSGELVKALTHVRYAASNEEY
RAIFRGVQLEFSPQGFRAVASDGYRLALYDLPLPQGFQAKAVVPARSVDEMVRVLKGADGAEADLALGEGVLALALEGGS
GVRMALRLMEGEFPDYQRVIPQEFALKVQVEGEALREAVRRVSVLSDRQNHRVDLLLEEGRILLSAEGDYGKGQEEVPAQ
VEGPGMAVAYNARYLLEALAPVGDRAHLGISGPTSPSLIWGDGEGYRAVVVPLRV

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped

COG id: COG0592

COG function: function code L; DNA polymerase sliding clamp subunit (PCNA homolog)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790136, Length=343, Percent_Identity=26.8221574344023, Blast_Score=112, Evalue=5e-26,

Paralogues:

None

Copy number: 5954 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001001
- InterPro:   IPR022635
- InterPro:   IPR022637
- InterPro:   IPR022634 [H]

Pfam domain/function: PF00712 DNA_pol3_beta; PF02767 DNA_pol3_beta_2; PF02768 DNA_pol3_beta_3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 40521; Mature: 40521

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNITVPKKLLSDQLSLLERIVPSRSANPLYTYLGLYAEEGALILFGTNGEVDLEVRLPAE
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEEEECCCCEEEEEECCCC
AQSLPRVLVPAQPFFQLVRSLPGDLVALGLASEPGQGGQLELSSGRFRTRLSLAPAEGYP
HHHCCEEECCCHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECCCCEEEEEEECCCCCCC
ELLVPEGEDKGAFPLRTRMPSGELVKALTHVRYAASNEEYRAIFRGVQLEFSPQGFRAVA
CEEECCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCHHHHHHHCCCEEEECCCCCCHHH
SDGYRLALYDLPLPQGFQAKAVVPARSVDEMVRVLKGADGAEADLALGEGVLALALEGGS
CCCEEEEEEECCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCC
GVRMALRLMEGEFPDYQRVIPQEFALKVQVEGEALREAVRRVSVLSDRQNHRVDLLLEEG
CHHHHHHHHCCCCCCHHHHCCCHHEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEECC
RILLSAEGDYGKGQEEVPAQVEGPGMAVAYNARYLLEALAPVGDRAHLGISGPTSPSLIW
EEEEEECCCCCCCCCCCCCEECCCCEEEEECHHHHHHHHCCCCCCEEECCCCCCCCCEEE
GDGEGYRAVVVPLRV
ECCCCCEEEEEEEEC
>Mature Secondary Structure
MNITVPKKLLSDQLSLLERIVPSRSANPLYTYLGLYAEEGALILFGTNGEVDLEVRLPAE
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEEEECCCCEEEEEECCCC
AQSLPRVLVPAQPFFQLVRSLPGDLVALGLASEPGQGGQLELSSGRFRTRLSLAPAEGYP
HHHCCEEECCCHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECCCCEEEEEEECCCCCCC
ELLVPEGEDKGAFPLRTRMPSGELVKALTHVRYAASNEEYRAIFRGVQLEFSPQGFRAVA
CEEECCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCHHHHHHHCCCEEEECCCCCCHHH
SDGYRLALYDLPLPQGFQAKAVVPARSVDEMVRVLKGADGAEADLALGEGVLALALEGGS
CCCEEEEEEECCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCC
GVRMALRLMEGEFPDYQRVIPQEFALKVQVEGEALREAVRRVSVLSDRQNHRVDLLLEEG
CHHHHHHHHCCCCCCHHHHCCCHHEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEECC
RILLSAEGDYGKGQEEVPAQVEGPGMAVAYNARYLLEALAPVGDRAHLGISGPTSPSLIW
EEEEEECCCCCCCCCCCCCEECCCCEEEEECHHHHHHHHCCCCCCEEECCCCCCCCCEEE
GDGEGYRAVVVPLRV
ECCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9079919; 8226640 [H]