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The map label for this gene is aroA

Identifier: 54297329

GI number: 54297329

Start: 1531152

End: 1532453

Strand: Direct

Name: aroA

Synonym: lpp1374

Alternate gene names: 54297329

Gene position: 1531152-1532453 (Clockwise)

Preceding gene: 54297328

Following gene: 54297330

Centisome position: 43.7

GC content: 41.55

Gene sequence:

>1302_bases
ATGTTGAATTTTATAAGTAAACCAGTTGGCTGCCTTAAGGGCGAAATCACAGTACCTGGAGATAAATCCATTTCCCATCG
TTCTATTATTTTTGGCGCGATTGCTATTGGAACTTCAGTAATCGATGGTTTTTTAGATGGTGAAGATTGCATAGCTACCC
TTAAAGCATTCCAATCGATGGGTGTTAGGATAGAGGGGCCTGATAAGCAACGTGTCATTATTCATGGGGTTGGGAAATAT
GGTTTAAAACAACCTCAAAATATTATTGATTGTGTCAACTCAGGTACCAGTATGCGCTTGCTGGCTGGATTGCTTGCAGC
ACAACAATTTGATAGCCAGTTAACGGGAGACGAAAGTTTACTTAAACGCCCAATGTTAAGAATCAGTAGACCCTTAAGTC
AAATGGGTGCAGACGTTACTACTCAGGATGGGAAGCCGCCTATAGTAATCAAAGGCGGAAAAAAATTAAATGGAATACAT
TATGTTATGCCGGAAGCCAGTGCTCAGGTAAAGTCGTGCCTGTTGTTAGCTGGTATGTATGCTGAAGGACAAACAAAAAT
AACTGAAAATGCAGTCAGTCGGGATCATACCGAAAGAATGTTAAGAACATTTTCTTATCCAGTTCAGATACAAGATGGTG
CTATCGTAATTGATCGTAATGGCGAGTGCCATGGAACTCGTCTGAATATCCCAGGAGACATTTCATCTGCTGCTTTTTTT
ATTGTTGCAGCTTCTATTACTCCAGGCTCCGATGTTTTAATTCGTAATGTAGGTATTAATCCTACACGAACTGGCATTAT
TCATATTTTAACTGAAATGGGAGCGGACATAAGAGTTTTGAATCAACGTGCCTATGGAGAGGAACCAGTTGCTGATTTGC
ATATCAGATATTCCCAATTAAAAGGAATCGATATTCCTGCCTCTATGGTGCCTTTGGCCATTGATGAATTCCCGGTTATT
TTTATTGCAGCTGCTTGCGCACAAGGGAAAACAACTCTTCATGGAGCTAAAGAGCTGCGCTTGAAGGAAAGTGATCGTAT
TGGCGCGATGGTGGATGGCTTAAACCAATTGGGGGTTCACGCTGAGGGTTTTGATGATGGAATATTAATAGAGGGTGGAA
GTATACAGGGTGGTGAGGTTAATAGTCGAGGAGATCACCGTATTGCCATGTCATTTGCCATTGCTGGCGCTGTCGCCAGT
GCTCCTGTAACGATTAAAAACTGCGCCAATGTTGCAACTTCATTTCCATCTTTTGTTACTACCGCTAACATGCTTCATTT
TCAGATAGAGGAATACAGCTGA

Upstream 100 bases:

>100_bases
GAGGATTGCGAGCCAGTTTGTACAATGCCATGCCTATGGCTGGAGTTGATGCTCTCATTGAGTTTATGTCTGAATTTGCA
AAAGAAAATGGTTAATAAGC

Downstream 100 bases:

>100_bases
TGGTTTTTAATAATGAGGTTCCTGTCATTACGTTGGATGGTCCAAGTGGAACAGGAAAGGGGACAATTTGTCATTTGGTA
GCCAAGAGACTGCATTGGAA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MLNFISKPVGCLKGEITVPGDKSISHRSIIFGAIAIGTSVIDGFLDGEDCIATLKAFQSMGVRIEGPDKQRVIIHGVGKY
GLKQPQNIIDCVNSGTSMRLLAGLLAAQQFDSQLTGDESLLKRPMLRISRPLSQMGADVTTQDGKPPIVIKGGKKLNGIH
YVMPEASAQVKSCLLLAGMYAEGQTKITENAVSRDHTERMLRTFSYPVQIQDGAIVIDRNGECHGTRLNIPGDISSAAFF
IVAASITPGSDVLIRNVGINPTRTGIIHILTEMGADIRVLNQRAYGEEPVADLHIRYSQLKGIDIPASMVPLAIDEFPVI
FIAAACAQGKTTLHGAKELRLKESDRIGAMVDGLNQLGVHAEGFDDGILIEGGSIQGGEVNSRGDHRIAMSFAIAGAVAS
APVTIKNCANVATSFPSFVTTANMLHFQIEEYS

Sequences:

>Translated_433_residues
MLNFISKPVGCLKGEITVPGDKSISHRSIIFGAIAIGTSVIDGFLDGEDCIATLKAFQSMGVRIEGPDKQRVIIHGVGKY
GLKQPQNIIDCVNSGTSMRLLAGLLAAQQFDSQLTGDESLLKRPMLRISRPLSQMGADVTTQDGKPPIVIKGGKKLNGIH
YVMPEASAQVKSCLLLAGMYAEGQTKITENAVSRDHTERMLRTFSYPVQIQDGAIVIDRNGECHGTRLNIPGDISSAAFF
IVAASITPGSDVLIRNVGINPTRTGIIHILTEMGADIRVLNQRAYGEEPVADLHIRYSQLKGIDIPASMVPLAIDEFPVI
FIAAACAQGKTTLHGAKELRLKESDRIGAMVDGLNQLGVHAEGFDDGILIEGGSIQGGEVNSRGDHRIAMSFAIAGAVAS
APVTIKNCANVATSFPSFVTTANMLHFQIEEYS
>Mature_433_residues
MLNFISKPVGCLKGEITVPGDKSISHRSIIFGAIAIGTSVIDGFLDGEDCIATLKAFQSMGVRIEGPDKQRVIIHGVGKY
GLKQPQNIIDCVNSGTSMRLLAGLLAAQQFDSQLTGDESLLKRPMLRISRPLSQMGADVTTQDGKPPIVIKGGKKLNGIH
YVMPEASAQVKSCLLLAGMYAEGQTKITENAVSRDHTERMLRTFSYPVQIQDGAIVIDRNGECHGTRLNIPGDISSAAFF
IVAASITPGSDVLIRNVGINPTRTGIIHILTEMGADIRVLNQRAYGEEPVADLHIRYSQLKGIDIPASMVPLAIDEFPVI
FIAAACAQGKTTLHGAKELRLKESDRIGAMVDGLNQLGVHAEGFDDGILIEGGSIQGGEVNSRGDHRIAMSFAIAGAVAS
APVTIKNCANVATSFPSFVTTANMLHFQIEEYS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=434, Percent_Identity=29.9539170506912, Blast_Score=137, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_LEGPA (Q5X5E6)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_123698.1
- HSSP:   Q9S400
- ProteinModelPortal:   Q5X5E6
- SMR:   Q5X5E6
- STRING:   Q5X5E6
- GeneID:   3117819
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp1374
- LegioList:   lpp1374
- eggNOG:   COG0128
- HOGENOM:   HBG646626
- OMA:   PAPSRDH
- ProtClustDB:   PRK02427
- BioCyc:   LPNE297246:LPP1374-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 46247; Mature: 46247

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNFISKPVGCLKGEITVPGDKSISHRSIIFGAIAIGTSVIDGFLDGEDCIATLKAFQSM
CCCCCCCCHHHHCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
GVRIEGPDKQRVIIHGVGKYGLKQPQNIIDCVNSGTSMRLLAGLLAAQQFDSQLTGDESL
CCEEECCCCCEEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHH
LKRPMLRISRPLSQMGADVTTQDGKPPIVIKGGKKLNGIHYVMPEASAQVKSCLLLAGMY
HHHHHHHHHCCHHHHCCCCCCCCCCCCEEEECCCEECCEEEECCCCHHHHHHHHHHHHHC
AEGQTKITENAVSRDHTERMLRTFSYPVQIQDGAIVIDRNGECHGTRLNIPGDISSAAFF
CCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEECCCCCCCEEECCCCCCCCCEEE
IVAASITPGSDVLIRNVGINPTRTGIIHILTEMGADIRVLNQRAYGEEPVADLHIRYSQL
EEEEECCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEEHHCCCCCCCHHHEEEHHHH
KGIDIPASMVPLAIDEFPVIFIAAACAQGKTTLHGAKELRLKESDRIGAMVDGLNQLGVH
CCCCCCHHHHCEECCCCCEEEEEEHHHCCCCCCCCHHHHEECCCCCHHHHHHCHHHHCCC
AEGFDDGILIEGGSIQGGEVNSRGDHRIAMSFAIAGAVASAPVTIKNCANVATSFPSFVT
CCCCCCCEEEECCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCEEHHHHHHHHHCCCHHHH
TANMLHFQIEEYS
HCEEEEEEEECCC
>Mature Secondary Structure
MLNFISKPVGCLKGEITVPGDKSISHRSIIFGAIAIGTSVIDGFLDGEDCIATLKAFQSM
CCCCCCCCHHHHCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
GVRIEGPDKQRVIIHGVGKYGLKQPQNIIDCVNSGTSMRLLAGLLAAQQFDSQLTGDESL
CCEEECCCCCEEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHH
LKRPMLRISRPLSQMGADVTTQDGKPPIVIKGGKKLNGIHYVMPEASAQVKSCLLLAGMY
HHHHHHHHHCCHHHHCCCCCCCCCCCCEEEECCCEECCEEEECCCCHHHHHHHHHHHHHC
AEGQTKITENAVSRDHTERMLRTFSYPVQIQDGAIVIDRNGECHGTRLNIPGDISSAAFF
CCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEECCCCCCCEEECCCCCCCCCEEE
IVAASITPGSDVLIRNVGINPTRTGIIHILTEMGADIRVLNQRAYGEEPVADLHIRYSQL
EEEEECCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEEHHCCCCCCCHHHEEEHHHH
KGIDIPASMVPLAIDEFPVIFIAAACAQGKTTLHGAKELRLKESDRIGAMVDGLNQLGVH
CCCCCCHHHHCEECCCCCEEEEEEHHHCCCCCCCCHHHHEECCCCCHHHHHHCHHHHCCC
AEGFDDGILIEGGSIQGGEVNSRGDHRIAMSFAIAGAVASAPVTIKNCANVATSFPSFVT
CCCCCCCEEEECCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCEEHHHHHHHHHCCCHHHH
TANMLHFQIEEYS
HCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA