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The map label for this gene is fabD [H]

Identifier: 54297304

GI number: 54297304

Start: 1503185

End: 1504132

Strand: Direct

Name: fabD [H]

Synonym: lpp1349

Alternate gene names: 54297304

Gene position: 1503185-1504132 (Clockwise)

Preceding gene: 54297303

Following gene: 54297305

Centisome position: 42.9

GC content: 42.51

Gene sequence:

>948_bases
ATGGTAAAATCAGCATTTGTATTTCCTGGACAGGGATCGCAGTCTATCGGCATGTTGTCTGACTTTATGCCACAGTATAC
TGTTGTCACCGATGCTTTTGCAGAGGCCTCAGAGGCCTTAGGCTATGATTTGTGGGATTTGGTTCAAAATGGGCCAGAGA
CAAAGCTAAACCAGACTGAATACACGCAGGCTGCCATGTTAACTGCTGATGTTGCAATTTATCGCTTATTAATGCAATTA
GGCGTACCTCAGCCTCAAGTAATGGCTGGCCATAGCTTAGGGGAATACGCTGCTTTGGTTTGCGCTAATTCTTTATCTTT
AAAGGATGCCGCACAGTTAGTTGCTCGTAGAGGACAGGTGATGCAAAACGCTATTCCTCTGGGAGAGGGGGCTATGGCTG
CCATAGTAGGCTTATCTGATGAACAGGTTCGTTCATTGTGTGAGCAAGCCAGCACAGCCAATCATCTTGTTACCCCGGCG
AATTATAATGCCCTGGGCCAAATTGTTGTTGCTGGACATCGAGTGGCCGTTGATAAACTAATACAATTGGCTGAAGAGAC
TGGCGCTAGACTGGCAATGATAATTCCTGTAAGTGTGCCTTGTCATTGCCCTTTATTAAAAAATGCTGCGGAATTATTTG
CTGAAAATCTTGCTCAAATTGAATTTCAAATTCCTTCAGTCGATGTGATAAGCAATGTTGATTTAAGTATTTATCATTCC
ACCCAACATATAAGAGATAAACTCAAAGAGCAACTATACAGCCCTGTGCGTTGGGTTGAAACAGTTCAGTTAATTCAACA
GCGTGGAATTGAACTGGTTGTGGAGTGTGGACCAGGAAAAGTTCTGAACGGTTTGATAAAAAGAATTGAGAGAAATTTAA
CTACGATTAGCGTTTATGACACCATTAGTCTTGATCAAGTCATAGAGCGTTTACATATCCCAGTTTGA

Upstream 100 bases:

>100_bases
AAAGGGATGAAATATTATTAATTGAATCCTTTGGTGGTGGAATGACCTGGGGCGCTATGGTTATTCGTTACTAAATTAAT
TAATAAGGATTAATTCTATT

Downstream 100 bases:

>100_bases
GAGGAAACTAGATGATCAATTTAGAAGGTAAAATTGCATTAGTTACTGGTGCCAGCCGTGGCATAGGTCGTGCTGTTGCC
GAGAAATTGGCAAGAAATGG

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MVKSAFVFPGQGSQSIGMLSDFMPQYTVVTDAFAEASEALGYDLWDLVQNGPETKLNQTEYTQAAMLTADVAIYRLLMQL
GVPQPQVMAGHSLGEYAALVCANSLSLKDAAQLVARRGQVMQNAIPLGEGAMAAIVGLSDEQVRSLCEQASTANHLVTPA
NYNALGQIVVAGHRVAVDKLIQLAEETGARLAMIIPVSVPCHCPLLKNAAELFAENLAQIEFQIPSVDVISNVDLSIYHS
TQHIRDKLKEQLYSPVRWVETVQLIQQRGIELVVECGPGKVLNGLIKRIERNLTTISVYDTISLDQVIERLHIPV

Sequences:

>Translated_315_residues
MVKSAFVFPGQGSQSIGMLSDFMPQYTVVTDAFAEASEALGYDLWDLVQNGPETKLNQTEYTQAAMLTADVAIYRLLMQL
GVPQPQVMAGHSLGEYAALVCANSLSLKDAAQLVARRGQVMQNAIPLGEGAMAAIVGLSDEQVRSLCEQASTANHLVTPA
NYNALGQIVVAGHRVAVDKLIQLAEETGARLAMIIPVSVPCHCPLLKNAAELFAENLAQIEFQIPSVDVISNVDLSIYHS
TQHIRDKLKEQLYSPVRWVETVQLIQQRGIELVVECGPGKVLNGLIKRIERNLTTISVYDTISLDQVIERLHIPV
>Mature_315_residues
MVKSAFVFPGQGSQSIGMLSDFMPQYTVVTDAFAEASEALGYDLWDLVQNGPETKLNQTEYTQAAMLTADVAIYRLLMQL
GVPQPQVMAGHSLGEYAALVCANSLSLKDAAQLVARRGQVMQNAIPLGEGAMAAIVGLSDEQVRSLCEQASTANHLVTPA
NYNALGQIVVAGHRVAVDKLIQLAEETGARLAMIIPVSVPCHCPLLKNAAELFAENLAQIEFQIPSVDVISNVDLSIYHS
TQHIRDKLKEQLYSPVRWVETVQLIQQRGIELVVECGPGKVLNGLIKRIERNLTTISVYDTISLDQVIERLHIPV

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=327, Percent_Identity=30.2752293577982, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI27477045, Length=114, Percent_Identity=37.719298245614, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787334, Length=309, Percent_Identity=48.8673139158576, Blast_Score=301, Evalue=4e-83,
Organism=Caenorhabditis elegans, GI71984332, Length=294, Percent_Identity=29.9319727891156, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=295, Percent_Identity=27.1186440677966, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24665753, Length=305, Percent_Identity=34.4262295081967, Blast_Score=144, Evalue=1e-34,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34302; Mature: 34302

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKSAFVFPGQGSQSIGMLSDFMPQYTVVTDAFAEASEALGYDLWDLVQNGPETKLNQTE
CCCCEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCHHH
YTQAAMLTADVAIYRLLMQLGVPQPQVMAGHSLGEYAALVCANSLSLKDAAQLVARRGQV
HHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
MQNAIPLGEGAMAAIVGLSDEQVRSLCEQASTANHLVTPANYNALGQIVVAGHRVAVDKL
HHHCCCCCCCCHHHEECCCHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHCCHHHHHHHH
IQLAEETGARLAMIIPVSVPCHCPLLKNAAELFAENLAQIEFQIPSVDVISNVDLSIYHS
HHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEECCCCHHHCCCCEEEEEC
TQHIRDKLKEQLYSPVRWVETVQLIQQRGIELVVECGPGKVLNGLIKRIERNLTTISVYD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEC
TISLDQVIERLHIPV
CCCHHHHHHHHCCCC
>Mature Secondary Structure
MVKSAFVFPGQGSQSIGMLSDFMPQYTVVTDAFAEASEALGYDLWDLVQNGPETKLNQTE
CCCCEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCHHH
YTQAAMLTADVAIYRLLMQLGVPQPQVMAGHSLGEYAALVCANSLSLKDAAQLVARRGQV
HHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
MQNAIPLGEGAMAAIVGLSDEQVRSLCEQASTANHLVTPANYNALGQIVVAGHRVAVDKL
HHHCCCCCCCCHHHEECCCHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHCCHHHHHHHH
IQLAEETGARLAMIIPVSVPCHCPLLKNAAELFAENLAQIEFQIPSVDVISNVDLSIYHS
HHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEECCCCHHHCCCCEEEEEC
TQHIRDKLKEQLYSPVRWVETVQLIQQRGIELVVECGPGKVLNGLIKRIERNLTTISVYD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEC
TISLDQVIERLHIPV
CCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]