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The map label for this gene is guaD [H]

Identifier: 54297084

GI number: 54297084

Start: 1255222

End: 1255686

Strand: Direct

Name: guaD [H]

Synonym: lpp1129

Alternate gene names: 54297084

Gene position: 1255222-1255686 (Clockwise)

Preceding gene: 54297082

Following gene: 54297085

Centisome position: 35.83

GC content: 40.65

Gene sequence:

>465_bases
ATGGATTTTATAAAGCGTACTATCGAGCTGGCTCGAGAGAATGTGGGACATGGGGGCAGACCATTTGCTTGTCTTATAGT
TCAGAATGGAAAAATTCTTGCTGAAGCTACCAATACGGTCGCGCAAACCCATGATCCTACAGCCCATGCTGAAGTTAATG
CGATACGGATTGCTACAGCGAAATTAGGTTGTGAGCATTTATACGATTGCGATTTTTATATACTTGCTCATCCTTGCCCG
ATGTGCCTGGCCGCAATGTATTATTGTAGTCCCAGGAAAGTGATCTTTATCACGACGAGAGATGAATATAAAACCTATTA
TGTAGATGATCGAAAATACTTCACTCTTGAGAATTTTTATCAGGAGATCAATAAGCCATGGAGAGAACGTAAGATGCCTA
TGGAGCATAGACCGGACAAAGAGGCAATAGAAGTATATAAAATGCACCAGAAAAAAAAGTCTTAG

Upstream 100 bases:

>100_bases
TATTCTTTTTTTAGCCATTATGCTTTCCTGGATAGTTTCATTTGTTACTTTTTATATTATGGGAAATAATTAATAATTAT
GGGCTAAAAATGGGAAAAAA

Downstream 100 bases:

>100_bases
TCCAAATAACTGTTTAATATTTAAAACAGTTTGATTTTCAACCTTTAAAAAACTTTTATGTTTTAAAGTTCATAGGTTTG
TGTGATCACTTTCAATAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: GDEase; Guanase; Guanine aminase; Guanine aminohydrolase; GAH [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MDFIKRTIELARENVGHGGRPFACLIVQNGKILAEATNTVAQTHDPTAHAEVNAIRIATAKLGCEHLYDCDFYILAHPCP
MCLAAMYYCSPRKVIFITTRDEYKTYYVDDRKYFTLENFYQEINKPWRERKMPMEHRPDKEAIEVYKMHQKKKS

Sequences:

>Translated_154_residues
MDFIKRTIELARENVGHGGRPFACLIVQNGKILAEATNTVAQTHDPTAHAEVNAIRIATAKLGCEHLYDCDFYILAHPCP
MCLAAMYYCSPRKVIFITTRDEYKTYYVDDRKYFTLENFYQEINKPWRERKMPMEHRPDKEAIEVYKMHQKKKS
>Mature_154_residues
MDFIKRTIELARENVGHGGRPFACLIVQNGKILAEATNTVAQTHDPTAHAEVNAIRIATAKLGCEHLYDCDFYILAHPCP
MCLAAMYYCSPRKVIFITTRDEYKTYYVDDRKYFTLENFYQEINKPWRERKMPMEHRPDKEAIEVYKMHQKKKS

Specific function: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17554608, Length=155, Percent_Identity=29.6774193548387, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17541138, Length=136, Percent_Identity=30.1470588235294, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.3 [H]

Molecular weight: Translated: 18067; Mature: 18067

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFIKRTIELARENVGHGGRPFACLIVQNGKILAEATNTVAQTHDPTAHAEVNAIRIATA
CHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEECHHHHHHCCCCCCCCEEEEEEEEHH
KLGCEHLYDCDFYILAHPCPMCLAAMYYCSPRKVIFITTRDEYKTYYVDDRKYFTLENFY
HHCHHHHHCCCEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCEEEEHHHHH
QEINKPWRERKMPMEHRPDKEAIEVYKMHQKKKS
HHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDFIKRTIELARENVGHGGRPFACLIVQNGKILAEATNTVAQTHDPTAHAEVNAIRIATA
CHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEECHHHHHHCCCCCCCCEEEEEEEEHH
KLGCEHLYDCDFYILAHPCPMCLAAMYYCSPRKVIFITTRDEYKTYYVDDRKYFTLENFY
HHCHHHHHCCCEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCEEEEHHHHH
QEINKPWRERKMPMEHRPDKEAIEVYKMHQKKKS
HHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11101664 [H]