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The map label for this gene is blh [H]

Identifier: 54296804

GI number: 54296804

Start: 946208

End: 946915

Strand: Direct

Name: blh [H]

Synonym: lpp0844

Alternate gene names: 54296804

Gene position: 946208-946915 (Clockwise)

Preceding gene: 54296801

Following gene: 54296805

Centisome position: 27.01

GC content: 33.62

Gene sequence:

>708_bases
ATGATTTTCCACCAGCTATTTGATCAGGATTCCTGCACTTATACTTACCTGATAGGCTCTACTGTTAGCAAGCATGCAAT
TATTATTGATCCGGTACGATCACAAGTTTCGCATTATATTAATCTAATTAACAAGTTAGAATTAAATTTGGTTGCTTCAA
TTGATACACATTTACATGCTGATCATATTACTGGATCAGGCCAATTAACCATCCTTACTGATTGTCATTCTATGATAGGA
ATGGAAAGCAAAGCGAAATTTGTGCACATCAAATTTCATGATAATGAGATTTTAAATTTTGGAAATATTAAAATAAAGGC
TATGCACACGCCAGGGCATACTCCAGATTCCTATTGTTTTGTAATGGAAGATAGAATATTTACTGGCGACACTTTATTAA
TCAATGCTACAGGACGTACTGATTTTCAAAATGGTAGCGCCAGTGCGCAATATGACAGTCTTTTTAACAAACTTTTAAAA
TTACCGGGATTCATGAGAATATATCCTGGCCATGATTATAATCAAAAACAATATAGTACAATTGATGATGAGAAAAAAAA
TAATCCCAGATTGCAGGTAAAATCCAGGCAAGAGTATGTTGAAATGATGGGTAATCTGAATTTGTCTTTTCCTAAAAACA
TGCATTTTGCAGTTCCCGCCAACTTGAATAATGGATTAACTGAGCAGGAAGTTAATGCTTTAGTTTAA

Upstream 100 bases:

>100_bases
TCATTTTTGCGCAGATGAAAAAATAAAATATTTTTACTCAATTAATTCAAGTTATTAAACATGACTAATAACAAAAAGTT
TTTTTATAGGGATTGGTAAA

Downstream 100 bases:

>100_bases
AGATTATTATCATTTATTTTGTTATATTTTATTCATTTATCTAGTCTGGGATTTATAAAGATAAATTGCAATATAAGCTC
AAGATACTTTTGTAATTTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MIFHQLFDQDSCTYTYLIGSTVSKHAIIIDPVRSQVSHYINLINKLELNLVASIDTHLHADHITGSGQLTILTDCHSMIG
MESKAKFVHIKFHDNEILNFGNIKIKAMHTPGHTPDSYCFVMEDRIFTGDTLLINATGRTDFQNGSASAQYDSLFNKLLK
LPGFMRIYPGHDYNQKQYSTIDDEKKNNPRLQVKSRQEYVEMMGNLNLSFPKNMHFAVPANLNNGLTEQEVNALV

Sequences:

>Translated_235_residues
MIFHQLFDQDSCTYTYLIGSTVSKHAIIIDPVRSQVSHYINLINKLELNLVASIDTHLHADHITGSGQLTILTDCHSMIG
MESKAKFVHIKFHDNEILNFGNIKIKAMHTPGHTPDSYCFVMEDRIFTGDTLLINATGRTDFQNGSASAQYDSLFNKLLK
LPGFMRIYPGHDYNQKQYSTIDDEKKNNPRLQVKSRQEYVEMMGNLNLSFPKNMHFAVPANLNNGLTEQEVNALV
>Mature_235_residues
MIFHQLFDQDSCTYTYLIGSTVSKHAIIIDPVRSQVSHYINLINKLELNLVASIDTHLHADHITGSGQLTILTDCHSMIG
MESKAKFVHIKFHDNEILNFGNIKIKAMHTPGHTPDSYCFVMEDRIFTGDTLLINATGRTDFQNGSASAQYDSLFNKLLK
LPGFMRIYPGHDYNQKQYSTIDDEKKNNPRLQVKSRQEYVEMMGNLNLSFPKNMHFAVPANLNNGLTEQEVNALV

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=230, Percent_Identity=44.3478260869565, Blast_Score=196, Evalue=1e-50,
Organism=Homo sapiens, GI94538320, Length=168, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI94538322, Length=168, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI21703352, Length=171, Percent_Identity=28.6549707602339, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI116642887, Length=171, Percent_Identity=28.6549707602339, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538952, Length=230, Percent_Identity=42.6086956521739, Blast_Score=173, Evalue=7e-44,
Organism=Caenorhabditis elegans, GI17536925, Length=250, Percent_Identity=24.4, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6320478, Length=184, Percent_Identity=28.2608695652174, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324614, Length=187, Percent_Identity=31.0160427807487, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221330176, Length=226, Percent_Identity=43.8053097345133, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24667711, Length=169, Percent_Identity=28.9940828402367, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356335, Length=169, Percent_Identity=28.9940828402367, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24667703, Length=174, Percent_Identity=28.735632183908, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 26664; Mature: 26664

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFHQLFDQDSCTYTYLIGSTVSKHAIIIDPVRSQVSHYINLINKLELNLVASIDTHLHA
CCCHHHCCCCCCEEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHCEEEEEEECCEEEE
DHITGSGQLTILTDCHSMIGMESKAKFVHIKFHDNEILNFGNIKIKAMHTPGHTPDSYCF
EEECCCCCEEEEECCHHHHCCCCCCEEEEEEEECCCEEEECCEEEEEEECCCCCCCCEEE
VMEDRIFTGDTLLINATGRTDFQNGSASAQYDSLFNKLLKLPGFMRIYPGHDYNQKQYST
EEECEEEECCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCC
IDDEKKNNPRLQVKSRQEYVEMMGNLNLSFPKNMHFAVPANLNNGLTEQEVNALV
CCCCCCCCCEEEEECHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHCC
>Mature Secondary Structure
MIFHQLFDQDSCTYTYLIGSTVSKHAIIIDPVRSQVSHYINLINKLELNLVASIDTHLHA
CCCHHHCCCCCCEEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHCEEEEEEECCEEEE
DHITGSGQLTILTDCHSMIGMESKAKFVHIKFHDNEILNFGNIKIKAMHTPGHTPDSYCF
EEECCCCCEEEEECCHHHHCCCCCCEEEEEEEECCCEEEECCEEEEEEECCCCCCCCEEE
VMEDRIFTGDTLLINATGRTDFQNGSASAQYDSLFNKLLKLPGFMRIYPGHDYNQKQYST
EEECEEEECCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCC
IDDEKKNNPRLQVKSRQEYVEMMGNLNLSFPKNMHFAVPANLNNGLTEQEVNALV
CCCCCCCCCEEEEECHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]