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The map label for this gene is dcd

Identifier: 54295795

GI number: 54295795

Start: 3291317

End: 3291883

Strand: Reverse

Name: dcd

Synonym: lpl2885

Alternate gene names: 54295795

Gene position: 3291883-3291317 (Counterclockwise)

Preceding gene: 54295796

Following gene: 54295791

Centisome position: 98.39

GC content: 43.03

Gene sequence:

>567_bases
GTGTCAATCAAATCAGACAGATGGATAGAGAAAATGGCCCTTGAGCATGGGATGATTTCTCCATTTCAGGCCGGTCAAGT
GCGAGAAAACCAAAATGGTAGGATTATTTCTTATGGCGTCTCCAGTTATGGGTATGATGTTCGCTGTTCGAATGAATTCA
AGATTTTTACGAATATTAATTCAGCGATTGTTGATCCCAAGGCGTTTGATGAAAATAGCTTTGTAGATGTTCAGTCTGAT
GTCTGCATTATTCCCCCCAATTCGTTTGCCTTGGCAAGAACTGTCGAATATTTCCGTATACCCCGCAATATATTAACGAT
ATGCTTAGGTAAATCCACTTACGCTCGTTGCGGGATTATAGTGAATGTTACTCCTCTGGAACCGGAATGGGAGGGGCATG
TTACTCTCGAGTTCTCCAATACGACCACTTTGCCAGCCAAGATTTATGCGTATGAGGGTGTTGCTCAAATGCTGTTTTTA
GAGGCTAATGAGGTTTGTGCTGTTTCTTATCGTGATCGAAACGGAAAGTACCAGGGACAAACCGGGGTTACACTACCACG
CACTTAG

Upstream 100 bases:

>100_bases
GAAGTTTCAATCATCTTATTCTGTATAATTTCCCAAAACAAACTTTCGTTTCATTGACTTTTATGATAGAAATCTATCTT
TTTAAGAAAAGAGGAATATC

Downstream 100 bases:

>100_bases
GATGAAAAATAAAATTTAATCTTTATCCAAAAGTGGGAACTTGGCTCGCGACGAATTGACCCGCTCCCGTAATTCCTTTC
CAGGTTTAAAGTGAGGACTG

Product: deoxycytidine triphosphate deaminase

Products: NA

Alternate protein names: dCTP deaminase

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MSIKSDRWIEKMALEHGMISPFQAGQVRENQNGRIISYGVSSYGYDVRCSNEFKIFTNINSAIVDPKAFDENSFVDVQSD
VCIIPPNSFALARTVEYFRIPRNILTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTTLPAKIYAYEGVAQMLFL
EANEVCAVSYRDRNGKYQGQTGVTLPRT

Sequences:

>Translated_188_residues
MSIKSDRWIEKMALEHGMISPFQAGQVRENQNGRIISYGVSSYGYDVRCSNEFKIFTNINSAIVDPKAFDENSFVDVQSD
VCIIPPNSFALARTVEYFRIPRNILTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTTLPAKIYAYEGVAQMLFL
EANEVCAVSYRDRNGKYQGQTGVTLPRT
>Mature_187_residues
SIKSDRWIEKMALEHGMISPFQAGQVRENQNGRIISYGVSSYGYDVRCSNEFKIFTNINSAIVDPKAFDENSFVDVQSDV
CIIPPNSFALARTVEYFRIPRNILTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTTLPAKIYAYEGVAQMLFLE
ANEVCAVSYRDRNGKYQGQTGVTLPRT

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCD_LEGPA (Q5X0R9)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_125329.1
- ProteinModelPortal:   Q5X0R9
- SMR:   Q5X0R9
- STRING:   Q5X0R9
- GeneID:   3119409
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp3027
- LegioList:   lpp3027
- eggNOG:   COG0717
- HOGENOM:   HBG553199
- OMA:   MEYFRIP
- ProtClustDB:   PRK00416
- BioCyc:   LPNE297246:LPP3027-MONOMER
- HAMAP:   MF_00146
- InterPro:   IPR011962
- InterPro:   IPR008180
- TIGRFAMs:   TIGR02274

Pfam domain/function: PF00692 dUTPase

EC number: =3.5.4.13

Molecular weight: Translated: 21137; Mature: 21006

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKSDRWIEKMALEHGMISPFQAGQVRENQNGRIISYGVSSYGYDVRCSNEFKIFTNIN
CCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEEEECCCCCEEEEECCCEEEEEECC
SAIVDPKAFDENSFVDVQSDVCIIPPNSFALARTVEYFRIPRNILTICLGKSTYARCGII
CEEECCCCCCCCCEEEECCCEEEECCCCCCHHHHHHHHHCCCHHEEEEECCCCHHEEEEE
VNVTPLEPEWEGHVTLEFSNTTTLPAKIYAYEGVAQMLFLEANEVCAVSYRDRNGKYQGQ
EEEECCCCCCCCEEEEEECCCCCCCEEEEEHHCHHEEEEEECCCEEEEEEECCCCCCCCC
TGVTLPRT
CCEECCCC
>Mature Secondary Structure 
SIKSDRWIEKMALEHGMISPFQAGQVRENQNGRIISYGVSSYGYDVRCSNEFKIFTNIN
CCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEEEECCCCCEEEEECCCEEEEEECC
SAIVDPKAFDENSFVDVQSDVCIIPPNSFALARTVEYFRIPRNILTICLGKSTYARCGII
CEEECCCCCCCCCEEEECCCEEEECCCCCCHHHHHHHHHCCCHHEEEEECCCCHHEEEEE
VNVTPLEPEWEGHVTLEFSNTTTLPAKIYAYEGVAQMLFLEANEVCAVSYRDRNGKYQGQ
EEEECCCCCCCCEEEEEECCCCCCCEEEEEHHCHHEEEEEECCCEEEEEEECCCCCCCCC
TGVTLPRT
CCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA